Published in Nat Med on August 04, 2011
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease. J Am Soc Nephrol (2014) 1.09
Primary focal and segmental glomerulosclerosis and soluble factor urokinase-type plasminogen activator receptor. World J Nephrol (2013) 0.92
Podocyte-actin dynamics in health and disease. Nat Rev Nephrol (2016) 0.85
Cyclic nucleotide signalling in kidney fibrosis. Int J Mol Sci (2015) 0.80
Urine soluble urokinase-type plasminogen activator receptor levels correlate with proteinuria in Puumala hantavirus infection. J Intern Med (2014) 0.78
Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35
Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet (2010) 5.68
Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N Engl J Med (1996) 4.41
Hereditary proteinuria syndromes and mechanisms of proteinuria. N Engl J Med (2006) 4.26
Modification of kidney barrier function by the urokinase receptor. Nat Med (2007) 4.01
Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling. J Am Soc Nephrol (2010) 2.52
Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med (2010) 2.32
Recurrence of idiopathic nephrotic syndrome after renal transplantation. Lancet (1972) 1.71
The spectrum of focal segmental glomerulosclerosis: new insights. Curr Opin Nephrol Hypertens (2008) 1.61
Humoral permeability factors in the nephrotic syndrome: a compendium and prospectus. J Nephrol (2002) 0.84
Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature (2005) 5.54
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet (2005) 5.53
Podocyte biology and response to injury. J Am Soc Nephrol (2002) 3.25
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis. Nat Genet (2009) 3.20
The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans. J Am Soc Nephrol (2010) 3.15
Population-based risk assessment of APOL1 on renal disease. J Am Soc Nephrol (2011) 2.81
Mechanical stretch induces podocyte hypertrophy in vitro. Kidney Int (2005) 2.39
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol (2006) 2.32
TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol (2008) 2.23
A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. Kidney Int (2010) 2.22
Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int (2004) 2.21
Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol (2005) 2.18
BTBR Ob/Ob mutant mice model progressive diabetic nephropathy. J Am Soc Nephrol (2010) 2.16
Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease. Am J Pathol (2013) 2.12
Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol (2003) 2.12
Inducible rodent models of acquired podocyte diseases. Am J Physiol Renal Physiol (2008) 2.06
Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int (2003) 2.03
Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res (2013) 1.82
NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele. J Clin Invest (2002) 1.81
Mutational and Biological Analysis of alpha-actinin-4 in focal segmental glomerulosclerosis. J Am Soc Nephrol (2005) 1.80
Cellular response to injury in membranous nephropathy. J Am Soc Nephrol (2005) 1.77
Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci U S A (2008) 1.70
Genetic variation in APOL1 associates with younger age at hemodialysis initiation. J Am Soc Nephrol (2011) 1.70
Genetics of kidney failure and the evolving story of APOL1. J Clin Invest (2011) 1.69
Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest (2003) 1.69
p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency. Kidney Int (2005) 1.67
A SNP streak model for the identification of genetic regions identical-by-descent. Stat Appl Genet Mol Biol (2008) 1.63
Metabolite profiling identifies markers of uremia. J Am Soc Nephrol (2010) 1.63
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol (2012) 1.59
Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem (2006) 1.58
Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol (2004) 1.58
Activation of a local renin angiotensin system in podocytes by glucose. Am J Physiol Renal Physiol (2008) 1.56
The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. J Clin Invest (2003) 1.53
Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity. Proc Natl Acad Sci U S A (2007) 1.53
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing. Nat Genet (2013) 1.52
Establishment of conditionally immortalized mouse glomerular parietal epithelial cells in culture. J Am Soc Nephrol (2008) 1.51
Effects of cyclosporine in osteopontin null mice. Kidney Int (2002) 1.47
De novo expression of podocyte proteins in parietal epithelial cells during experimental glomerular disease. Am J Physiol Renal Physiol (2009) 1.45
APOL1 variants and kidney disease in people of recent African ancestry. Nat Rev Nephrol (2013) 1.43
Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: role of p53 and Bcl-2-related family proteins. J Am Soc Nephrol (2005) 1.43
Using population admixture to help complete maps of the human genome. Nat Genet (2013) 1.35
NPHS2 R229Q functional variant is associated with microalbuminuria in the general population. Kidney Int (2004) 1.35
ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo. Kidney Int (2005) 1.34
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion. Am J Physiol Endocrinol Metab (2009) 1.32
Reversibility of structural and functional damage in a model of advanced diabetic nephropathy. J Am Soc Nephrol (2013) 1.30
A new function for parietal epithelial cells: a second glomerular barrier. Am J Physiol Renal Physiol (2009) 1.29
De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy. Am J Physiol Renal Physiol (2011) 1.28
Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells. J Clin Invest (2009) 1.28
Podocyte injury and targeting therapy: an update. Curr Opin Nephrol Hypertens (2006) 1.25
The enigmatic parietal epithelial cell is finally getting noticed: a review. Kidney Int (2009) 1.24
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. J Clin Invest (2014) 1.24
Viable podocytes detach in experimental diabetic nephropathy: potential mechanism underlying glomerulosclerosis. Nephron Exp Nephrol (2004) 1.23
TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription. Am J Physiol Cell Physiol (2009) 1.21
DNA damage is a novel response to sublytic complement C5b-9-induced injury in podocytes. J Clin Invest (2003) 1.18
Retinoids augment the expression of podocyte proteins by glomerular parietal epithelial cells in experimental glomerular disease. Nephron Exp Nephrol (2012) 1.17
Plasma apolipoprotein L1 levels do not correlate with CKD. J Am Soc Nephrol (2013) 1.15
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data. BMC Genet (2005) 1.14
Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion. Proc Natl Acad Sci U S A (2010) 1.13
Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS. Am J Physiol Renal Physiol (2013) 1.13
p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo. Kidney Int (2010) 1.12
α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts. PLoS One (2010) 1.11
Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2). Proc Natl Acad Sci U S A (2011) 1.10
Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis. Kidney Int (2012) 1.10
Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis. Kidney Int (2005) 1.09
Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology. Am J Pathol (2004) 1.08
Biophysical properties of normal and diseased renal glomeruli. Am J Physiol Cell Physiol (2010) 1.07
The cyclin-dependent kinase inhibitor p21 is required for TGF-beta1-induced podocyte apoptosis. Kidney Int (2005) 1.07
Dexamethasone's prosurvival benefits in podocytes require extracellular signal-regulated kinase phosphorylation. Nephron Exp Nephrol (2008) 1.06
NPHS2 variation in focal and segmental glomerulosclerosis. BMC Nephrol (2008) 1.04
Aberrant Notch1-dependent effects on glomerular parietal epithelial cells promotes collapsing focal segmental glomerulosclerosis with progressive podocyte loss. Kidney Int (2013) 1.04
Mannose receptor 2 attenuates renal fibrosis. J Am Soc Nephrol (2011) 1.04
Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury. J Am Soc Nephrol (2006) 1.04
Podocyte proliferation and differentiation in glomerular disease: role of cell-cycle regulatory proteins. Nephrol Dial Transplant (2003) 1.03
Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4. Biophys J (2008) 1.02
Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2. Nephrol Dial Transplant (2011) 1.02
Cyclin I protects podocytes from apoptosis. J Biol Chem (2006) 1.01
Cell cycle regulatory proteins in podocyte health and disease. Nephron Exp Nephrol (2007) 1.00
Both cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes. Am J Physiol Renal Physiol (2012) 1.00
Cell cycle and glomerular disease: a minireview. Nephron Exp Nephrol (2005) 1.00
Dystroglycan does not contribute significantly to kidney development or function, in health or after injury. Am J Physiol Renal Physiol (2011) 1.00
Experimental Models of Membranous Nephropathy. Drug Discov Today Dis Models (2010) 1.00
Intravital imaging of podocyte calcium in glomerular injury and disease. J Clin Invest (2014) 0.99
Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation. J Am Soc Nephrol (2005) 0.97
Patients with ACTN4 mutations demonstrate distinctive features of glomerular injury. J Am Soc Nephrol (2009) 0.97
Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling. J Am Soc Nephrol (2013) 0.97
Novel siRNA delivery system to target podocytes in vivo. PLoS One (2010) 0.96
Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells. J Clin Invest (2009) 0.96
SSeCKS sequesters cyclin D1 in glomerular parietal epithelial cells and influences proliferative injury in the glomerulus. Lab Invest (2012) 0.95
Cross-link-governed dynamics of biopolymer networks. Phys Rev Lett (2010) 0.95
The hypertrophic effect of transforming growth factor-beta is reduced in the absence of cyclin-dependent kinase-inhibitors p21 and p27. J Am Soc Nephrol (2002) 0.95
Podocyte disorders: Core Curriculum 2011. Am J Kidney Dis (2011) 0.94
Podocyte biology for the bedside. Am J Kidney Dis (2011) 0.94
The rapamycin derivative RAD inhibits mesangial cell migration through the CDK-inhibitor p27KIP1. Lab Invest (2004) 0.93
The contribution of podocytes to chronic allograft nephropathy. Nephron Exp Nephrol (2008) 0.93
The renin-angiotensin system in glomerular podocytes: mediator of glomerulosclerosis and link to hypertensive nephropathy. Curr Hypertens Rep (2006) 0.93
Microarray and bioinformatics analysis of gene expression in experimental membranous nephropathy. Nephron Exp Nephrol (2009) 0.93
Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis. J Mol Biol (2007) 0.93
TRPC6 in glomerular health and disease: what we know and what we believe. Semin Cell Dev Biol (2006) 0.93
The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration. Am J Pathol (2013) 0.92