Published in Am J Respir Cell Mol Biol on January 01, 2012
Chitinase dependent control of protozoan cyst burden in the brain. PLoS Pathog (2012) 1.68
Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology. Nat Chem Biol (2012) 1.21
Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog (2015) 1.02
Innate immune responses in house dust mite allergy. ISRN Allergy (2013) 0.92
Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. Int Immunopharmacol (2013) 0.85
PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production. Mucosal Immunol (2012) 0.82
Acidic chitinase primes the protective immune response to gastrointestinal nematodes. Nat Immunol (2016) 0.82
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites. Proc Natl Acad Sci U S A (2015) 0.81
Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease. Cell (2017) 0.78
Gastric and intestinal proteases resistance of chicken acidic chitinase nominates chitin-containing organisms for alternative whole edible diets for poultry. Sci Rep (2017) 0.77
Protease resistance of porcine acidic mammalian chitinase under gastrointestinal conditions implies that chitin-containing organisms can be sustainable dietary resources. Sci Rep (2017) 0.75
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science (2011) 6.19
Mast cells as "tunable" effector and immunoregulatory cells: recent advances. Annu Rev Immunol (2005) 5.22
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A (2004) 4.59
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem Biophys Res Commun (2003) 2.82
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J Neurosci (2010) 2.78
An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment. J Immunol (2007) 2.46
Cell size and growth rate are major determinants of replicative lifespan. Cell Cycle (2011) 2.26
Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells. J Biol Chem (2007) 2.06
IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis. J Immunol (2007) 1.96
The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. J Immunol (2008) 1.82
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system. Mol Pharmacol (2010) 1.81
Chitinase dependent control of protozoan cyst burden in the brain. PLoS Pathog (2012) 1.68
Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit. J Med Chem (2012) 1.55
Allergen-independent maternal transmission of asthma susceptibility. J Immunol (2003) 1.42
Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infect Immun (2005) 1.31
An fMRI study of cerebral processing of brush-evoked allodynia in neuropathic pain patients. Neuroimage (2006) 1.27
Bone marrow production of lung cells: the impact of G-CSF, cardiotoxin, graded doses of irradiation, and subpopulation phenotype. Exp Hematol (2006) 1.20
The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders? Mol Cell Neurosci (2009) 1.16
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learn Mem (2006) 1.16
Broca's area supports enhanced visuospatial cognition in orchestral musicians. J Neurosci (2007) 1.16
Homing and conversion of murine hematopoietic stem cells to lung. Blood Cells Mol Dis (2004) 1.15
Gob-5 contributes to goblet cell hyperplasia and modulates pulmonary tissue inflammation. Am J Respir Cell Mol Biol (2006) 1.13
Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling. J Immunol (2006) 1.13
Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology. Anal Biochem (2006) 1.11
Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood. J Biol Chem (2007) 1.11
Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain. PLoS One (2011) 1.10
Measured solar ultraviolet radiation exposures of outdoor workers in Queensland in the building and construction industry. Photochem Photobiol (2003) 1.07
Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality. J Leukoc Biol (2010) 1.01
Cloning and expression of MRG receptors in macaque, mouse, and human. Brain Res Mol Brain Res (2005) 1.01
Kinetic characterization of recombinant human acidic mammalian chitinase. Biochemistry (2006) 1.01
Human alveolar macrophage gene responses to Mycobacterium tuberculosis strains H37Ra and H37Rv. Am J Respir Cell Mol Biol (2008) 1.01
Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity. J Allergy Clin Immunol (2012) 1.01
TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation. J Allergy Clin Immunol (2005) 1.01
Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis. Atherosclerosis (2008) 0.98
Role of breast milk in a mouse model of maternal transmission of asthma susceptibility. J Immunol (2006) 0.98
Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease. Am J Pathol (2010) 0.98
In vitro modeling of human alveolar macrophage smoke exposure: enhanced inflammation and impaired function. Exp Lung Res (2008) 0.98
Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem (2008) 0.98
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase. Protein Sci (2009) 0.97
Maternal allergic contact dermatitis causes increased asthma risk in offspring. Respir Res (2007) 0.97
Cytokine pathways in allergic disease. Toxicol Pathol (2012) 0.97
Identification and characterization of a leucine-rich repeat kinase 2 (LRRK2) consensus phosphorylation motif. PLoS One (2010) 0.96
Meeting report: consensus statement-Parkinson's disease and the environment: collaborative on health and the environment and Parkinson's Action Network (CHE PAN) conference 26-28 June 2007. Environ Health Perspect (2008) 0.94
A fluorescent assay suitable for inhibitor screening and vanin tissue quantification. Anal Biochem (2009) 0.93
A comparison of strength training, self-management, and the combination for early osteoarthritis of the knee. Arthritis Care Res (Hoboken) (2010) 0.93
Three-dimensional sonography of the endometrium and adjacent myometrium: preliminary observations. J Ultrasound Med (2006) 0.93
Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner. J Immunol (2010) 0.92
Amygdala activity contributes to the dissociative effect of cannabis on pain perception. Pain (2013) 0.92
A global benchmark study using affinity-based biosensors. Anal Biochem (2008) 0.91
IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13. J Immunol (2005) 0.89
MicroRNA-27b targets gremlin 1 to modulate fibrotic responses in pulmonary cells. J Cell Biochem (2014) 0.89
Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults. J Allergy Clin Immunol (2010) 0.89
Smoke exposure of human macrophages reduces HDAC3 activity, resulting in enhanced inflammatory cytokine production. Pulm Pharmacol Ther (2012) 0.88
Functional expression of human and mouse P2Y12 receptors in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2004) 0.88
Identification and characterization of acidic mammalian chitinase inhibitors. J Med Chem (2010) 0.87
Retention of 125I-labeled recombinant human bone morphogenetic protein-2 by biphasic calcium phosphate or a composite sponge in a rabbit posterolateral spine arthrodesis model. J Orthop Res (2002) 0.87
A role for endothelial selectins in allergic and nonallergic inflammatory disease. Ann Allergy Asthma Immunol (2007) 0.86
Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J Immunol (2009) 0.86
Smell identification ability in twin pairs discordant for Parkinson's disease. Mov Disord (2005) 0.86
Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma. Cytokine (2009) 0.85
Identification and quantification of osteopontin splice variants in the plasma of lung cancer patients using immunoaffinity capture and targeted mass spectrometry. Biomarkers (2011) 0.85
Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78. Biochim Biophys Acta (2007) 0.84
SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1. Eur J Immunol (2008) 0.84
Characterization of protein kinase C theta activation loop autophosphorylation and the kinase domain catalytic mechanism. Biochemistry (2005) 0.83
Stem cell plasticity: an overview. Blood Cells Mol Dis (2004) 0.82
An IL-4/IL-13 dual antagonist reduces lung inflammation, airway hyperresponsiveness, and IgE production in mice. Am J Respir Cell Mol Biol (2013) 0.82
Differentiation hotspots: the deterioration of hierarchy and stochasm. Blood Cells Mol Dis (2004) 0.82
A method for clonal analysis of epidermal growth factor-responsive neural progenitors. J Neurosci Methods (2002) 0.81
Interleukin-6 neutralization alleviates pulmonary inflammation in mice exposed to cigarette smoke and poly(I:C). Clin Sci (Lond) (2013) 0.81
The stem cell continuum. Ann N Y Acad Sci (2005) 0.80
Identification of new cell size control genes in S. cerevisiae. Cell Div (2012) 0.80
The pathology and immunology of atopic dermatitis. Inflamm Allergy Drug Targets (2011) 0.80
Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice. Immunology (2014) 0.80
A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-κB pathway. J Biomol Screen (2013) 0.79
An approach to quantifying N-linked glycoproteins by enzyme-catalyzed 18O3-labeling of solid-phase enriched glycopeptides. Anal Chem (2010) 0.79
Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell line. Protein Expr Purif (2012) 0.79
Central representation of somatic sensations in the parietal operculum (SII) and insula. Eur Neurol (2004) 0.78
CAT-2 amplifies the agonist-evoked force of airway smooth muscle by enhancing spermine-mediated phosphatidylinositol-(4)-phosphate-5-kinase-gamma activity. Am J Physiol Lung Cell Mol Physiol (2007) 0.78
Evolutionary and biochemical differences between human and monkey acidic mammalian chitinases. Gene (2009) 0.78
Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum. BMC Pulm Med (2010) 0.78
A growing role for hypertrophy in senescence. FEMS Yeast Res (2012) 0.78
Effect of von Willebrand factor on the pharmacokinetics of recombinant human platelet glycoprotein Ibalpha-immunoglobulin G1 chimeric proteins. Pharm Res (2006) 0.78
Binding characterization of the interleukin-13 signaling complex and development of a ternary time-resolved fluorescence resonance energy transfer assay. Anal Biochem (2008) 0.75
Partnership working is key to providing seamless care. BMJ (2012) 0.75
Discovery of isoquinolinone indole acetic acids as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseases. J Med Chem (2014) 0.75
On harnessing the power of medical students to reach their peers. Explore (NY) (2014) 0.75
"Supersaturated" self-assembled charge-selective interfacial layers for organic solar cells. J Am Chem Soc (2014) 0.75
Introduction to the pulmonary research group's symposium: Preclinical research in COPD and pulmonary fibrosis. Pulm Pharmacol Ther (2012) 0.75