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1
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Signal transducer and activator of transcription proteins in leukemias.
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Blood
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2.23
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2
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Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.
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Nat Med
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2005
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2.06
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3
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Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism.
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Nat Immunol
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2006
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2.05
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4
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Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress.
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Immunity
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2004
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1.76
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5
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Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties.
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Cytokine Growth Factor Rev
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2003
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1.72
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6
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Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival.
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Blood
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2002
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1.67
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7
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Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction.
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J Immunol
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2002
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1.65
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8
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IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells.
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J Clin Invest
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2011
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1.46
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9
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Targeting signal transducer and activator of transcription signaling pathway in leukemias.
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J Clin Oncol
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2009
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1.40
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10
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Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis.
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Blood
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2002
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1.34
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11
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Monitoring photobleaching and hemodynamic responses to HPPH-mediated photodynamic therapy of head and neck cancer: a case report.
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Opt Express
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2010
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1.30
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12
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Interleukin-31 and oncostatin-M mediate distinct signaling reactions and response patterns in lung epithelial cells.
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J Biol Chem
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2006
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1.27
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13
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Interleukin-6 in surgery, trauma, and critical care part II: clinical implications.
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J Intensive Care Med
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2011
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1.26
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14
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Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.
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Mol Biol Cell
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2002
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1.24
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15
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Systemic inflammation in cardiovascular and periodontal disease: comparative study.
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Clin Diagn Lab Immunol
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2002
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1.19
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16
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Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo.
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Immunology
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2005
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1.11
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17
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The acute phase protein haptoglobin regulates host immunity.
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J Leukoc Biol
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2008
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1.10
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18
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Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung.
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Lung Cancer
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2006
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1.09
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19
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Cross-linking of signal transducer and activator of transcription 3--a molecular marker for the photodynamic reaction in cells and tumors.
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Clin Cancer Res
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2007
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1.08
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20
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Conjugation of 2-(1'-hexyloxyethyl)-2-devinylpyropheophorbide-a (HPPH) to carbohydrates changes its subcellular distribution and enhances photodynamic activity in vivo.
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J Med Chem
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2009
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1.07
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21
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Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation.
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Clin Cancer Res
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2006
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1.05
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22
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Analytic review: Interleukin-6 in surgery, trauma, and critical care: part I: basic science.
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J Intensive Care Med
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2011
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1.04
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23
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Photodynamic therapy causes cross-linking of signal transducer and activator of transcription proteins and attenuation of interleukin-6 cytokine responsiveness in epithelial cells.
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Cancer Res
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2004
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1.01
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24
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Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine.
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Cancer Lett
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2004
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0.99
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25
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Photodynamic therapy mediates immediate loss of cellular responsiveness to cytokines and growth factors.
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Cancer Res
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2003
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0.98
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26
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Photophysical, electrochemical characteristics and cross-linking of STAT-3 protein by an efficient bifunctional agent for fluorescence image-guided photodynamic therapy.
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Photochem Photobiol Sci
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2007
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0.94
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27
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Regulation of a lymphocyte-endothelial-IL-6 trans-signaling axis by fever-range thermal stress: hot spot of immune surveillance.
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Cytokine
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2007
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0.94
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28
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Transformation of human bronchial epithelial cells alters responsiveness to inflammatory cytokines.
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BMC Cancer
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2005
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0.93
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Development of head and neck squamous cell carcinoma is associated with altered cytokine responsiveness.
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Mol Cancer Res
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2004
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0.92
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30
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Photodynamic therapy with 3-(1'-hexyloxyethyl) pyropheophorbide a for cancer of the oral cavity.
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Clin Cancer Res
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0.92
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31
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Regulated expression of the IL-31 receptor in bronchial and alveolar epithelial cells, pulmonary fibroblasts, and pulmonary macrophages.
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J Interferon Cytokine Res
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2008
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0.89
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32
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Interlesion differences in the local photodynamic therapy response of oral cavity lesions assessed by diffuse optical spectroscopies.
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Biomed Opt Express
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2012
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0.89
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33
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Enhancer-dependent inhibition of mouse renin transcription by inflammatory cytokines.
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Am J Physiol Renal Physiol
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2004
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0.86
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34
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FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins.
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Oncogene
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2002
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0.85
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35
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Cell-type selective phototoxicity achieved with chlorophyll-a derived photosensitizers in a co-culture system of primary human tumor and normal lung cells.
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Photochem Photobiol
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2011
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0.85
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36
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Phase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia.
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Cancer
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2011
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0.85
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37
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What is new in cytokine research related to trauma/critical care.
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J Intensive Care Med
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2006
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0.85
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38
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Epigenetic regulation of signal transducer and activator of transcription 3 in acute myeloid leukemia.
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Leuk Res
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2008
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0.84
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39
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DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.
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Hepatology
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2003
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0.83
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40
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In vitro cellular uptake and dimerization of signal transducer and activator of transcription-3 (STAT3) identify the photosensitizing and imaging-potential of isomeric photosensitizers derived from chlorophyll-a and bacteriochlorophyll-a.
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J Med Chem
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2011
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0.82
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41
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Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop.
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Mol Biol Evol
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2002
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0.81
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42
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The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure.
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Genomics
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2002
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0.81
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43
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Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus.
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Diabetes Metab Res Rev
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2005
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0.80
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44
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Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress.
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Eur J Immunol
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2007
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0.79
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45
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Administration of two macrophage-derived interferon-gamma-inducing factors (IL-12 and IL-15) induces a lethal systemic inflammatory response in mice that is dependent on natural killer cells but does not require interferon-gamma.
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Cell Immunol
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2002
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0.78
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46
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Down-regulation of signal transducer and activator of transcription 3 improves human acute myeloid leukemia-derived dendritic cell function.
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Leuk Res
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2013
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0.77
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47
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Effect of Metalation on Porphyrin-Based Bifunctional Agents in Tumor Imaging and Photodynamic Therapy.
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Bioconjug Chem
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2016
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0.76
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Proinflammatory cytokines increase hepatocellular carcinoma cells thermotolerance: evidence of how local inflammation may negatively impact radiofrequency ablation local control rates.
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J Surg Res
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2007
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0.75
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49
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A unique form of haptoglobin produced by murine hematopoietic cells supports B-cell survival, differentiation and immune response.
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Mol Immunol
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2013
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0.75
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50
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Highly Effective Dual-Function Near-Infrared (NIR) Photosensitizer for Fluorescence Imaging and Photodynamic Therapy (PDT) of Cancer.
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J Med Chem
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2016
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0.75
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51
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Structural and Epimeric Isomers of HPPH [3-Devinyl 3-{1-(1-hexyloxy) ethyl}pyropheophorbide-a]: Effects on Uptake and Photodynamic Therapy of Cancer.
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ACS Chem Biol
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2017
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0.75
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