|
1
|
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
Nat Genet
|
2013
|
8.24
|
|
2
|
A common coding variant in CASP8 is associated with breast cancer risk.
|
Nat Genet
|
2007
|
7.35
|
|
3
|
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
|
Nat Genet
|
2009
|
7.30
|
|
4
|
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies.
|
PLoS Med
|
2010
|
6.04
|
|
5
|
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.
|
J Natl Cancer Inst
|
2010
|
4.54
|
|
6
|
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
|
Nat Genet
|
2013
|
4.35
|
|
7
|
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
Nat Genet
|
2013
|
3.81
|
|
8
|
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types.
|
Hum Mutat
|
2011
|
3.63
|
|
9
|
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.
|
Nat Genet
|
2011
|
3.37
|
|
10
|
Genome-wide association analysis identifies three new breast cancer susceptibility loci.
|
Nat Genet
|
2012
|
3.20
|
|
11
|
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.
|
Hum Mol Genet
|
2011
|
2.72
|
|
12
|
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
|
Am J Hum Genet
|
2013
|
2.24
|
|
13
|
Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.
|
Lancet Oncol
|
2009
|
2.17
|
|
14
|
The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study.
|
Breast Cancer Res Treat
|
2008
|
1.96
|
|
15
|
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk.
|
PLoS Genet
|
2013
|
1.88
|
|
16
|
19p13.1 is a triple-negative-specific breast cancer susceptibility locus.
|
Cancer Res
|
2012
|
1.81
|
|
17
|
Common breast cancer susceptibility loci are associated with triple-negative breast cancer.
|
Cancer Res
|
2011
|
1.65
|
|
18
|
Association of ESR1 gene tagging SNPs with breast cancer risk.
|
Hum Mol Genet
|
2009
|
1.58
|
|
19
|
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.
|
Hum Mol Genet
|
2011
|
1.56
|
|
20
|
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.
|
PLoS Genet
|
2013
|
1.56
|
|
21
|
Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells.
|
Proc Natl Acad Sci U S A
|
2010
|
1.42
|
|
22
|
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
|
Am J Hum Genet
|
2013
|
1.39
|
|
23
|
The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes.
|
Eur J Hum Genet
|
2006
|
1.32
|
|
24
|
Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium.
|
Cancer Epidemiol Biomarkers Prev
|
2009
|
1.29
|
|
25
|
CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer.
|
J Clin Oncol
|
2012
|
1.29
|
|
26
|
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
|
Hum Mutat
|
2012
|
1.26
|
|
27
|
Independent prognostic value of screen detection in invasive breast cancer.
|
J Natl Cancer Inst
|
2011
|
1.23
|
|
28
|
Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2011
|
1.23
|
|
29
|
The role of genetic breast cancer susceptibility variants as prognostic factors.
|
Hum Mol Genet
|
2012
|
1.23
|
|
30
|
Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).
|
PLoS One
|
2012
|
1.13
|
|
31
|
Family history, genetic testing, and clinical risk prediction: pooled analysis of CHEK2 1100delC in 1,828 bilateral breast cancers and 7,030 controls.
|
Cancer Epidemiol Biomarkers Prev
|
2009
|
1.13
|
|
32
|
Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study.
|
Breast Cancer Res
|
2007
|
1.12
|
|
33
|
A role for XRCC2 gene polymorphisms in breast cancer risk and survival.
|
J Med Genet
|
2011
|
1.10
|
|
34
|
Use of insulin and insulin analogs and risk of cancer - systematic review and meta-analysis of observational studies.
|
Curr Drug Saf
|
2013
|
1.05
|
|
35
|
The spectrum of ATM missense variants and their contribution to contralateral breast cancer.
|
Breast Cancer Res Treat
|
2007
|
1.03
|
|
36
|
CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women.
|
J Med Genet
|
2011
|
1.01
|
|
37
|
Obtaining 'fresh' consent for genetic research with biological samples archived 10 years ago.
|
Eur J Cancer
|
2009
|
1.01
|
|
38
|
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.
|
Hum Mol Genet
|
2013
|
1.00
|
|
39
|
Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
|
Breast Cancer Res
|
2014
|
0.99
|
|
40
|
Use of metformin and survival of diabetic women with breast cancer.
|
Curr Drug Saf
|
2013
|
0.98
|
|
41
|
9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.95
|
|
42
|
Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.
|
Cancer Epidemiol Biomarkers Prev
|
2010
|
0.91
|
|
43
|
Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors.
|
Int J Cancer
|
2014
|
0.90
|
|
44
|
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
|
J Natl Cancer Inst
|
2015
|
0.90
|
|
45
|
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.
|
Breast Cancer Res
|
2014
|
0.89
|
|
46
|
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
|
Hum Mol Genet
|
2013
|
0.88
|
|
47
|
Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.
|
Genet Epidemiol
|
2013
|
0.86
|
|
48
|
ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism.
|
BMC Cancer
|
2008
|
0.86
|
|
49
|
Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive familial breast cancer cases.
|
Eur J Cancer
|
2013
|
0.85
|
|
50
|
An information-theoretic analysis of genetics, gender and age in cancer patients.
|
PLoS One
|
2008
|
0.83
|
|
51
|
Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome.
|
Int J Cancer
|
2012
|
0.82
|
|
52
|
Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups.
|
Breast Cancer Res Treat
|
2011
|
0.81
|
|
53
|
Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.
|
PLoS One
|
2012
|
0.80
|
|
54
|
Genetic variants in TGFβ-1 and PAI-1 as possible risk factors for cardiovascular disease after radiotherapy for breast cancer.
|
Radiother Oncol
|
2011
|
0.79
|
|
55
|
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy.
|
Breast Cancer Res
|
2015
|
0.79
|
|
56
|
Tumour tissue: who is in control?
|
Lancet Oncol
|
2009
|
0.78
|
|
57
|
[Secondary use of human tissue: consent and better information required].
|
Ned Tijdschr Geneeskd
|
2009
|
0.77
|
|
58
|
[Gene expression classifiers in the prognosis of breast cancer].
|
Ned Tijdschr Geneeskd
|
2014
|
0.77
|
|
59
|
[Biobanks and the return of results to donors].
|
Ned Tijdschr Geneeskd
|
2014
|
0.76
|
|
60
|
The BIO-PIN paradigm: 'access to' or 'return of' results?
|
Nat Rev Cancer
|
2011
|
0.75
|
|
61
|
Cause-specific Mortality in a Population-based Cohort of 9799 Women Treated for Ductal Carcinoma In Situ.
|
Ann Surg
|
2017
|
0.75
|
|
62
|
[Consent for the secondary use of human residual tissue: the patient is best served by an 'opting-out' procedure].
|
Ned Tijdschr Geneeskd
|
2012
|
0.75
|