Published in Virology on May 01, 1990
Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function. J Virol (1993) 2.16
Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen. Mol Cell Biol (1993) 1.98
Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activators. J Virol (1992) 1.68
Identification of lentivirus tat functional domains through generation of equine infectious anemia virus/human immunodeficiency virus type 1 tat gene chimeras. J Virol (1991) 1.61
Detailed mutational analysis of TAR RNA: critical spacing between the bulge and loop recognition domains. Nucleic Acids Res (1991) 1.44
Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure. J Virol (1992) 1.43
The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA. Proc Natl Acad Sci U S A (1991) 1.32
Mutational analysis of the equine infectious anemia virus Tat-responsive element. J Virol (1991) 1.28
Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins. J Virol (1990) 1.25
Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an arginine-rich motif required for transactivation. EMBO J (1991) 1.24
Protein B23 is an important human factor for the nucleolar localization of the human immunodeficiency virus protein Tat. J Virol (1997) 1.16
Maedi-visna virus and caprine arthritis encephalitis virus genomes encode a Vpr-like but no Tat protein. J Virol (2003) 1.06
Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides. J Virol (1994) 1.00
Functional comparison of the basic domains of the Tat proteins of human immunodeficiency virus types 1 and 2 in trans activation. J Virol (1992) 0.92
Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator. J Virol (1995) 0.90
Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm. J Virol (1996) 0.88
Site-specific cleavage of the transactivation response site of human immunodeficiency virus RNA with a tat-based chemical nuclease. Proc Natl Acad Sci U S A (1992) 0.83
Molecular mechanisms in the dramatic enhancement of HIV-1 Tat transduction by cationic liposomes. FASEB J (2012) 0.79
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect (2011) 17.47
Two CD95 (APO-1/Fas) signaling pathways. EMBO J (1998) 10.42
Scaling of connectivity in marine populations. Science (2005) 8.41
Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature (1982) 5.11
An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J Virol (1992) 4.85
Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity. Proc Natl Acad Sci U S A (1983) 4.32
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell (1994) 3.86
Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys). Proc Natl Acad Sci U S A (1986) 3.76
A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J (1995) 3.70
A comprehensive panel of near-full-length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1. J Virol (1998) 3.65
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci U S A (1995) 3.28
Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate. Virology (1994) 3.16
Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis. Nucleic Acids Res (1989) 2.72
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci (1998) 2.55
Physical mapping of a large-plaque mutation of adenovirus type 2. J Virol (1979) 2.50
Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA. Proc Natl Acad Sci U S A (1981) 2.34
Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci U S A (1991) 2.17
BH3-only proteins in apoptosis and beyond: an overview. Oncogene (2008) 2.13
Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology (1996) 2.12
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat Med (2000) 2.11
[177Lu-DOTAOTyr3]octreotate: comparison with [111In-DTPAo]octreotide in patients. Eur J Nucl Med (2001) 2.11
Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J Biol Chem (1998) 2.06
Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases. J Neurosci (2000) 2.04
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol (2000) 2.04
Adenovirus 2 Ip+ locus codes for a 19 kd tumor antigen that plays an essential role in cell transformation. Cell (1983) 2.01
Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release. J Biol Chem (1997) 1.97
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci U S A (2000) 1.97
Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose. J Nucl Med (1998) 1.97
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis. J Hepatol (2001) 1.93
The phylogenetic history of immunodeficiency viruses. Nature (1988) 1.89
Organic aerosol formation downwind from the Deepwater Horizon oil spill. Science (2011) 1.89
Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J Biol Chem (1998) 1.81
Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation. Cell (1984) 1.80
Neuroimaging in child and adolescent psychiatry. J Am Acad Child Adolesc Psychiatry (1990) 1.73
Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. Am J Pathol (1999) 1.71
PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels. Mol Cell Biol (1992) 1.67
Treatment of patients with gastro-entero-pancreatic (GEP) tumours with the novel radiolabelled somatostatin analogue [177Lu-DOTA(0),Tyr3]octreotate. Eur J Nucl Med Mol Imaging (2003) 1.66
Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53. Virology (1989) 1.66
An efficient and simple method of DNA extraction from whole blood and cell lines to identify infectious agents. J Virol Methods (1991) 1.65
Distinct cis-acting regions in U3 regulate trans-activation of the human spumaretrovirus long terminal repeat by the viral bel1 gene product. Nucleic Acids Res (1991) 1.63
NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis. Am J Physiol (1998) 1.63
Molecular cloning and primary nucleotide sequence analysis of a distinct human immunodeficiency virus isolate reveal significant divergence in its genomic sequences. Proc Natl Acad Sci U S A (1986) 1.61
Apoptosis after traumatic human spinal cord injury. J Neurosurg (1998) 1.58
Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J Biol Chem (1999) 1.57
The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions. J Org Chem (2001) 1.57
Transactivation of human immunodeficiency virus by herpesviruses. Oncogene (1987) 1.57
Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism. Transplantation (1999) 1.56
trans-activation of viral enhancers including long terminal repeat of the human immunodeficiency virus by the hepatitis B virus X protein. Virology (1989) 1.55
[177Lu-DOTA(0),Tyr3] octreotate for somatostatin receptor-targeted radionuclide therapy. Int J Cancer (2001) 1.53
Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic. Curr Opin Immunol (1999) 1.49
Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex. Mol Cell Biol (2007) 1.49
Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotype. Virology (1990) 1.48
Superinfection of a chimpanzee with a second strain of human immunodeficiency virus. J Virol (1987) 1.47
19-kDa tumor antigen coded by early region E1b of adenovirus 2 is required for efficient synthesis and for protection of viral DNA. J Biol Chem (1984) 1.47
A unique pattern of integrated viral genes in hamster cells transformed by highly oncogenic human adenovirus 12. Cell (1976) 1.45
Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol (2000) 1.43
Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infection. Virology (1994) 1.42
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes. Circ Res (1999) 1.42
Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation. Virology (1995) 1.41
An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor. Oncogene (1988) 1.41
Enhanced infectivity of adenovirus type 2 DNA and a DNA-protein complex. J Virol (1978) 1.40
Enhanced ras oncogene mediated cell transformation and tumorigenesis by adenovirus 2 mutants lacking the C-terminal region of E1a protein. Oncogene (1989) 1.40
Nicotinamide adenine dinucleotide stimulates oligomerization, interaction with adenovirus E1A and an intrinsic dehydrogenase activity of CtBP. FEBS Lett (2003) 1.38
Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Res (2001) 1.36
Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system. Proc Natl Acad Sci U S A (2000) 1.35
Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7. J Biol Chem (1998) 1.34
The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation. Nucleic Acids Res (1996) 1.33
SV40 T antigen abrogates p53-mediated transcriptional activity. Oncogene (1993) 1.31
Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes. Genes Dev (1987) 1.30
Evidence that a second tumor antigen coded by adenovirus early gene region E1a is required for efficient cell transformation. Proc Natl Acad Sci U S A (1985) 1.27
BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia. Neurobiol Dis (2000) 1.26
Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1. J Virol (1992) 1.25
Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an arginine-rich motif required for transactivation. EMBO J (1991) 1.24
Relationship between the transforming and transcriptional regulatory functions of adenovirus 2 E1a oncogene. Virology (1987) 1.24
V3-independent determinants of macrophage tropism in a primary human immunodeficiency virus type 1 isolate. J Virol (1995) 1.24
Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins. J Virol (2001) 1.24
Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses. Proc Natl Acad Sci U S A (1991) 1.24
Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation. Proc Natl Acad Sci U S A (1995) 1.24
Functional dissection of the human spumaretrovirus transactivator identifies distinct classes of dominant-negative mutants. J Virol (1993) 1.24
p53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: suppression by E1B 19K and Bcl-2 proteins. Cell Growth Differ (1995) 1.23
BH3-only protein BIK induces caspase-independent cell death with autophagic features in Bcl-2 null cells. Oncogene (2007) 1.22
Pre-early polypeptides of bacteriophages T5 and BF23. J Virol (1977) 1.21
Crystal structure of lactoperoxidase at 2.4 A resolution. J Mol Biol (2007) 1.19
ATP-dependent steps in apoptotic signal transduction. Cancer Res (1999) 1.17
Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities. Oncogene (1998) 1.17
Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2. J Biol Chem (2005) 1.17
Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins. J Biol Chem (1998) 1.17
Association of class I histone deacetylases with transcriptional corepressor CtBP. FEBS Lett (2003) 1.16
Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells. Cancer Res (2002) 1.16
Genetic identification of adenovirus type 5 genes that influence viral spread. J Virol (2006) 1.14
Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization. Virology (1995) 1.14