Published in J Med Chem on August 26, 2011
Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr (2013) 1.08
[6]-shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2. Carcinogenesis (2013) 0.85
Effect of ginger and cinnamon intake on oxidative stress and exercise performance and body composition in Iranian female athletes. Int J Prev Med (2013) 0.83
Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot study. Metabolism (2012) 0.82
Hepatoprotective effect of herb formula KIOM2012H against nonalcoholic fatty liver disease. Nutrients (2015) 0.76
N-[(1,3-Benzodioxol-5-yl)meth-yl]-4-methyl-benzamide: an analogue of capsaicin. Acta Crystallogr Sect E Struct Rep Online (2013) 0.75
High-fat diet intake from senescence inhibits the attenuation of cell functions and the degeneration of villi with aging in the small intestine, and inhibits the attenuation of lipid absorption ability in SAMP8 mice. J Clin Biochem Nutr (2015) 0.75
Changes of serum adipocytokines and body weight following Zingiber officinale supplementation in obese women: a RCT. Eur J Nutr (2015) 0.75
Heat-evoked activation of the ion channel, TRPV4. J Neurosci (2002) 4.69
KIF5B-RET fusions in lung adenocarcinoma. Nat Med (2012) 4.38
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes (2002) 3.04
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nat Genet (2010) 2.81
Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A (2006) 2.29
Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. J Clin Endocrinol Metab (2008) 1.91
Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer. Cell Metab (2012) 1.84
Adrenergic regulation of clock gene expression in mouse liver. Proc Natl Acad Sci U S A (2003) 1.70
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet (2002) 1.63
Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. Diabetes (2002) 1.63
Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue. J Biol Chem (2008) 1.48
Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse. Eur J Neurosci (2002) 1.41
Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association. J Hum Genet (2009) 1.38
Gastrin-releasing peptide mediates photic entrainable signals to dorsal subsets of suprachiasmatic nucleus via induction of Period gene in mice. Mol Pharmacol (2002) 1.38
Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo. J Biol Chem (2002) 1.36
Genome-wide association study identifies three novel loci for type 2 diabetes. Hum Mol Genet (2013) 1.28
The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice. Eur J Neurosci (2009) 1.28
Potential roles of large mafs in cell lineages and developing pancreas. Pancreas (2006) 1.27
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet (2012) 1.23
In vivo monitoring of peripheral circadian clocks in the mouse. Curr Biol (2012) 1.19
Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice. Eur J Neurosci (2004) 1.19
Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects. J Hum Genet (2007) 1.19
Intra-axonal patterning: intrinsic compartmentalization of the axonal membrane in Drosophila neurons. Neuron (2009) 1.16
Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet. J Biol Rhythms (2007) 1.15
Mechanical strain on the human skull in a humanoid robotic model. Am J Orthod Dentofacial Orthop (2004) 1.11
Genetic variants of human beta-defensin-1 and chronic obstructive pulmonary disease. Biochem Biophys Res Commun (2002) 1.09
A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver: relationship to anti-obesity. J Lipid Res (2002) 1.08
The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women. Sleep Med (2011) 1.08
Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei. Eur J Neurosci (2004) 1.07
A balanced diet is necessary for proper entrainment signals of the mouse liver clock. PLoS One (2009) 1.07
Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet. Am J Physiol Endocrinol Metab (2007) 1.07
CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis. Nat Med (2012) 1.06
Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain. Pain (2005) 1.06
Titanium-based transition-edge photon number resolving detector with 98% detection efficiency with index-matched small-gap fiber coupling. Opt Express (2011) 1.05
Combination of starvation interval and food volume determines the phase of liver circadian rhythm in Per2::Luc knock-in mice under two meals per day feeding. Am J Physiol Gastrointest Liver Physiol (2010) 1.05
Brain response to a humanoid robot in areas implicated in the perception of human emotional gestures. PLoS One (2010) 1.05
Refeeding after fasting elicits insulin-dependent regulation of Per2 and Rev-erbα with shifts in the liver clock. J Biol Rhythms (2011) 1.04
Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice. Neurosci Res (2005) 1.04
Crosstalk between the circadian clock circuitry and the immune system. Chronobiol Int (2013) 1.03
Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice. J Circadian Rhythms (2009) 1.03
Attenuated fever response in mice lacking TRPV1. Neurosci Lett (2004) 1.03
Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice. Horm Behav (2007) 1.03
Autoimmune diabetes in HIV-infected patients on highly active antiretroviral therapy. J Clin Endocrinol Metab (2010) 1.02
Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus. Am J Hum Genet (2010) 1.01
Inhibition of increases in blood glucose and serum neutral fat by Momordica charantia saponin fraction. Biosci Biotechnol Biochem (2007) 1.00
Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction. J Allergy Clin Immunol (2011) 1.00
Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner. FEBS Lett (2006) 0.99
Genetic variations and haplotypes of CYP2C19 in a Japanese population. Drug Metab Pharmacokinet (2005) 0.99
Berberine inhibits hepatic stellate cell proliferation and prevents experimental liver fibrosis. Biol Pharm Bull (2009) 0.98
Clinical features and surgical outcomes of cervical spondylotic myelopathy in patients aged 80 years or older: a multi-center retrospective study. Eur Spine J (2011) 0.98
Endoscopic submucosal dissection for rectal carcinoid tumors. Surg Endosc (2009) 0.98
Motor discoordination in mutant mice lacking junctophilin type 3. Biochem Biophys Res Commun (2002) 0.97
Pdx1-transfected adipose tissue-derived stem cells differentiate into insulin-producing cells in vivo and reduce hyperglycemia in diabetic mice. Int J Dev Biol (2010) 0.96
Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice. J Physiol (2003) 0.96
Midline governs axon pathfinding by coordinating expression of two major guidance systems. Genes Dev (2009) 0.95
PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders. Biochem Biophys Res Commun (2007) 0.95
The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia. Proc Natl Acad Sci U S A (2008) 0.95
Individual nucleic amplification technology does not prevent all hepatitis B virus transmission by blood transfusion. Transfusion (2006) 0.94
Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects. Drug Metab Dispos (2009) 0.94
The adjustment and manipulation of biological rhythms by light, nutrition, and abused drugs. Adv Drug Deliv Rev (2010) 0.93
Meal frequency patterns determine the phase of mouse peripheral circadian clocks. Sci Rep (2012) 0.92
Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin. J Neurosci Res (2002) 0.92
Dietary intake is associated with human chronotype as assessed by both morningness-eveningness score and preferred midpoint of sleep in young Japanese women. Int J Food Sci Nutr (2011) 0.92
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese. J Hum Genet (2004) 0.92
Circadian Clock mutation in dams disrupts nursing behavior and growth of pups. Endocrinology (2006) 0.91
Time of day and nutrients in feeding govern daily expression rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liver. J Biol Chem (2010) 0.91
Identification of tuberculosis-associated proteins in whole blood supernatant. BMC Infect Dis (2011) 0.91
Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse. FEBS Lett (2004) 0.91
Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese. Pharmacogenet Genomics (2006) 0.91
Clinical features and surgical outcomes of lumbar spinal stenosis in patients aged 80 years or older: a multi-center retrospective study. Arch Orthop Trauma Surg (2013) 0.91
Development of an objective endoscopic surgical skill assessment system for pediatric surgeons: suture ligature model of the crura of the diaphragm in infant fundoplication. Pediatr Surg Int (2013) 0.91
Effect of chronic ethanol exposure on the liver of Clock-mutant mice. J Circadian Rhythms (2009) 0.90
Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver. Am J Physiol Endocrinol Metab (2004) 0.90
A patient with diabetes and breast cancer in whom virilization was caused by a testosterone-producing mature cystic teratoma containing a Brenner tumor. Am J Med Sci (2011) 0.89
Restricted feeding induces daily expression of clock genes and Pai-1 mRNA in the heart of Clock mutant mice. FEBS Lett (2002) 0.89
Vasoactive intestinal peptide produces long-lasting changes in neural activity in the suprachiasmatic nucleus. J Neurophysiol (2013) 0.89
Identification of a human cDNA sequence which encodes a novel membrane-associated protein containing a zinc metalloprotease motif. DNA Res (2003) 0.89
Optimization of dosing schedule of daily inhalant dexamethasone to minimize phase shifting of clock gene expression rhythm in the lungs of the asthma mouse model. Endocrinology (2007) 0.89
Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism. J Circadian Rhythms (2012) 0.89
SV40 vectors carrying minimal sequence of viral origin with exchangeable capsids. Virology (2008) 0.88
Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver. Chronobiol Int (2010) 0.88
Role of IRS and PHIP on insulin-induced tyrosine phosphorylation and distribution of IRS proteins. Cell Struct Funct (2007) 0.88
Rapid-onset type 1 diabetes associated with cytomegalovirus infection and islet autoantibody synthesis. Intern Med (2007) 0.87
Neonatal alloimmune thrombocytopenia caused by an antibody specific for a newly identified allele of human platelet antigen-7. Transfusion (2010) 0.87
Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice. Br J Pharmacol (2014) 0.86
MafA is critical for maintenance of the mature beta cell phenotype in mice. Diabetologia (2014) 0.86