Published in Appl Biosaf on January 01, 2010
Three-dimensional organization of Rift Valley fever virus revealed by cryoelectron tomography. J Virol (2008) 1.56
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy. J Virol (2006) 1.34
Single-particle cryo-electron microscopy of Rift Valley fever virus. Virology (2009) 1.34
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol (2005) 9.11
Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science (2003) 7.91
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A (2005) 6.64
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci U S A (2005) 5.64
Genetic characterization of Zika virus strains: geographic expansion of the Asian lineage. PLoS Negl Trop Dis (2012) 5.31
Chikungunya virus and the global spread of a mosquito-borne disease. N Engl J Med (2015) 5.16
Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci U S A (2006) 4.84
Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells. Proc Natl Acad Sci U S A (2006) 4.54
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology (2002) 4.34
Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature (2006) 3.73
A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature (2013) 3.55
Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med (2012) 3.54
Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy. Nature (2008) 3.54
Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus. J Virol (2006) 3.45
Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J Virol (2004) 3.43
De novo backbone trace of GroEL from single particle electron cryomicroscopy. Structure (2008) 3.41
EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Res (2010) 3.32
Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates. J Virol (2010) 3.18
Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol (2006) 3.14
Protein structure fitting and refinement guided by cryo-EM density. Structure (2008) 3.12
Visualizing hepatitis C virus infections in human liver by two-photon microscopy. Gastroenterology (2009) 3.07
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology (2002) 3.02
Refinement of protein structures into low-resolution density maps using rosetta. J Mol Biol (2009) 2.94
The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell (2003) 2.89
Mechanism of folding chamber closure in a group II chaperonin. Nature (2010) 2.85
Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells. J Virol (2004) 2.76
Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nat Struct Biol (2003) 2.76
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat Mater (2011) 2.71
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem (2005) 2.70
NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. J Virol (2008) 2.62
Common ancestry of herpesviruses and tailed DNA bacteriophages. J Virol (2005) 2.60
Identification of secondary structure elements in intermediate-resolution density maps. Structure (2007) 2.60
Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells. J Am Chem Soc (2008) 2.56
Public health and biosecurity. Adaptations of avian flu virus are a cause for concern. Science (2012) 2.52
Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. J Virol (2010) 2.51
Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy. Structure (2004) 2.50
Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions. J Struct Biol (2010) 2.48
The pore structure of the closed RyR1 channel. Structure (2005) 2.42
A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A (2010) 2.41
3' nontranslated RNA signals required for replication of hepatitis C virus RNA. J Virol (2003) 2.41
Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc Natl Acad Sci U S A (2012) 2.39
Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc Natl Acad Sci U S A (2007) 2.38
Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32
Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure (2004) 2.30
Global surveillance of emerging Influenza virus genotypes by mass spectrometry. PLoS One (2007) 2.29
West Nile virus in Mexico: evidence of widespread circulation since July 2002. Emerg Infect Dis (2003) 2.27
Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure (2006) 2.26
Epistatic roles of E2 glycoprotein mutations in adaption of chikungunya virus to Aedes albopictus and Ae. aegypti mosquitoes. PLoS One (2009) 2.22
4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc Natl Acad Sci U S A (2010) 2.17
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity (2012) 2.13
Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes. Proc Natl Acad Sci U S A (2011) 2.12
Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus. Nat Struct Mol Biol (2010) 2.12
Venezuelan encephalitis emergence mediated by a phylogenetically predicted viral mutation. Proc Natl Acad Sci U S A (2006) 2.07
Refinement of protein structures by iterative comparative modeling and CryoEM density fitting. J Mol Biol (2006) 2.06
The history and evolution of human dengue emergence. Adv Virus Res (2008) 2.05
An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate. Structure (2006) 2.04
Arbovirus evolution in vivo is constrained by host alternation. Proc Natl Acad Sci U S A (2008) 2.04
Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proc Natl Acad Sci U S A (2011) 2.03
Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses. J Virol (2011) 1.99
Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus. Gastroenterology (2010) 1.96
Sequential adaptive mutations enhance efficient vector switching by Chikungunya virus and its epidemic emergence. PLoS Pathog (2011) 1.95
Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope glycoprotein. Proc Natl Acad Sci U S A (2004) 1.95
Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency. J Struct Biol (2012) 1.94
Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography. J Mol Biol (2006) 1.90
Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm. J Struct Biol (2007) 1.90
GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS. J Virol (2006) 1.86
Fever from the forest: prospects for the continued emergence of sylvatic dengue virus and its impact on public health. Nat Rev Microbiol (2011) 1.86
Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. J Virol (2009) 1.85
The molecular architecture of the eukaryotic chaperonin TRiC/CCT. Structure (2012) 1.80
DNA packaging and delivery machines in tailed bacteriophages. Curr Opin Struct Biol (2007) 1.79
Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate. PLoS Pathog (2012) 1.79
A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol (2005) 1.78
Chimeric alphavirus vaccine candidates for chikungunya. Vaccine (2008) 1.78
4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. EMBO J (2011) 1.77
Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication. Proc Natl Acad Sci U S A (2012) 1.73
Genome sequence and attenuating mutations in West Nile virus isolate from Mexico. Emerg Infect Dis (2004) 1.73
Direct access to the cooperative substructure of proteins and the protein ensemble via cold denaturation. Nat Struct Mol Biol (2004) 1.73
Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure. Structure (2011) 1.71
Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. J Mol Biol (2010) 1.71
A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol (2004) 1.70
Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A (2008) 1.68
Negevirus: a proposed new taxon of insect-specific viruses with wide geographic distribution. J Virol (2012) 1.67
Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins. Nat Struct Mol Biol (2007) 1.67
Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy. J Struct Biol (2005) 1.67
Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. J Virol (2010) 1.66
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus. PLoS Pathog (2008) 1.66
Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses. Nat Med (2013) 1.65
Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol Cell (2005) 1.65
Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology (2008) 1.64
Analysis of Venezuelan equine encephalitis virus capsid protein function in the inhibition of cellular transcription. J Virol (2007) 1.64
Definition of a conserved immunodominant domain on hepatitis C virus E2 glycoprotein by neutralizing human monoclonal antibodies. J Virol (2008) 1.63
Hepatitis A virus: from discovery to vaccines. Hepatology (2006) 1.63
JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles. J Struct Biol (2008) 1.62
Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein. Virology (2002) 1.62
Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism. PLoS Pathog (2011) 1.62