Platelet-rich plasma releasate inhibits inflammatory processes in osteoarthritic chondrocytes.

PubWeight™: 1.40‹?› | Rank: Top 5%

🔗 View Article (PMID 21856929)

Published in Am J Sports Med on August 19, 2011

Authors

Gerben M van Buul1, Wendy L M Koevoet, Nicole Kops, P Koen Bos, Jan A N Verhaar, Harrie Weinans, Monique R Bernsen, Gerjo J V M van Osch

Author Affiliations

1: Departments of Orthopaedics and Otorhinolaryngology, Erasmus MC, Dr. Molewaterplein 50, Rotterdam, the Netherlands.

Associated clinical trials:

Comparison of Acetaminophen and PRP Therapy for Knee OA | NCT01782885

Articles citing this

Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors. Stem Cell Res Ther (2013) 1.56

Platelet-rich plasma for managing pain and inflammation in osteoarthritis. Nat Rev Rheumatol (2013) 1.43

Addition of Mesenchymal Stem Cells to Autologous Platelet-Enhanced Fibrin Scaffolds in Chondral Defects: Does It Enhance Repair? J Bone Joint Surg Am (2016) 1.42

Use of a bioactive scaffold to stimulate anterior cruciate ligament healing also minimizes posttraumatic osteoarthritis after surgery. Am J Sports Med (2013) 1.26

State-of-the-Art management of knee osteoarthritis. World J Clin Cases (2015) 1.06

Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surg Sports Traumatol Arthrosc (2013) 1.05

Biology of platelet-rich plasma and its clinical application in cartilage repair. Arthritis Res Ther (2014) 1.04

No positive bone healing after using platelet rich plasma in a skeletal defect. An observational prospective cohort study. Int Orthop (2012) 1.00

Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions. BMC Vet Res (2015) 0.91

A novel hypothesis: the application of platelet-rich plasma can promote the clinical healing of white-white meniscal tears. Med Sci Monit (2012) 0.87

Platelet-rich plasma therapy for knee joint problems: review of the literature, current practice and legal perspectives in Korea. Knee Surg Relat Res (2012) 0.86

Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction. Knee Surg Sports Traumatol Arthrosc (2014) 0.85

Establishing proof of concept: Platelet-rich plasma and bone marrow aspirate concentrate may improve cartilage repair following surgical treatment for osteochondral lesions of the talus. World J Orthop (2012) 0.85

Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide. BMC Musculoskelet Disord (2015) 0.82

Advantages of Pure Platelet-Rich Plasma Compared with Leukocyte- and Platelet-Rich Plasma in Treating Rabbit Knee Osteoarthritis. Med Sci Monit (2016) 0.82

Platelet rich plasma and knee surgery. Biomed Res Int (2014) 0.81

Safety of intra-articular use of atelocollagen for enhanced tissue repair. Open Orthop J (2012) 0.80

Stimulation of the superficial zone protein and lubrication in the articular cartilage by human platelet-rich plasma. Am J Sports Med (2015) 0.80

Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis. Mol Med Rep (2016) 0.79

Platelet concentrate in bovine reproduction: effects on in vitro embryo production and after intrauterine administration in repeat breeder cows. Reprod Biol Endocrinol (2015) 0.79

Anti-inflammatory strategies in cartilage repair. Tissue Eng Part B Rev (2014) 0.78

Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics. Curr Rev Musculoskelet Med (2015) 0.78

Bridge-enhanced ACL repair: A review of the science and the pathway through FDA investigational device approval. Ann Biomed Eng (2015) 0.77

Biologic Treatments for Sports Injuries II Think Tank-Current Concepts, Future Research, and Barriers to Advancement, Part 3: Articular Cartilage. Orthop J Sports Med (2016) 0.76

The role of platelet gel in osteoarticular injuries of young and old patients. Immun Ageing (2014) 0.76

Learning about PRP using cell-based models. Muscles Ligaments Tendons J (2014) 0.76

Canine Platelet-Rich Plasma Systems: A Prospective Analysis. Front Vet Sci (2016) 0.76

Platelet-Rich Plasma May Improve Osteochondral Donor Site Healing in a Rabbit Model. Cartilage (2016) 0.76

Platelet-rich plasma application in chondrogenesis. Adv Biomed Res (2014) 0.75

Advances in sports nutrition, exercise and medicine: Olympic issues, the legacy and beyond. BMC Med (2012) 0.75

PRP in OA knee - update, current confusions and future options. SICOT J (2017) 0.75

Neotendon infilling of a full thickness rotator cuff foot print tear following ultrasound guided liquid platelet rich plasma injection and percutaneous tenotomy: favourable outcome up to one year. F1000Res (2013) 0.75

Intradiscal and intra-articular facet infiltrations with plasma rich in growth factors reduce pain in patients with chronic low back pain. J Craniovertebr Junction Spine (2016) 0.75

Comparative evaluation of leukocyte- and platelet-rich plasma and pure platelet-rich plasma for cartilage regeneration. Sci Rep (2017) 0.75

Decrease of serum biomarker of type II Collagen degradation (Coll2-1) by intra-articular injection of an autologous plasma-rich-platelet in patients with unilateral primary knee osteoarthritis. Eur J Rheumatol (2017) 0.75

Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration. Curr Stem Cell Rep (2016) 0.75

Management of Hepple Stage V Osteochondral Lesion of the Talus with a Platelet-Rich Plasma Scaffold. Biomed Res Int (2017) 0.75

Bio-modulators in platelet-rich plasma: a comparison of the amounts in products from healthy donors and patients produced with three different techniques. Blood Transfus (2013) 0.75

Platelet Derived Biomaterials for Therapeutic Use: Review of Technical Aspects. Indian J Hematol Blood Transfus (2016) 0.75

Articles by these authors

Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA (2010) 4.68

Platelet-rich plasma injections in acute muscle injury. N Engl J Med (2014) 2.92

Medial knee osteoarthritis treated by insoles or braces: a randomized trial. Clin Orthop Relat Res (2010) 2.53

Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial. Ann Intern Med (2008) 2.45

Quantitative evaluation of mechanical properties in tissue-engineered auricular cartilage. Tissue Eng Part B Rev (2013) 2.14

Knee injury and Osteoarthritis Outcome Score or International Knee Documentation Committee Subjective Knee Form: which questionnaire is most useful to monitor patients with an anterior cruciate ligament rupture in the short term? Arthroscopy (2013) 2.10

The Dutch version of the Knee Injury and Osteoarthritis Outcome Score: a validation study. Health Qual Life Outcomes (2008) 1.93

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in vivo microfocal computed tomography study. Arthritis Rheum (2011) 1.92

An improved segmentation method for in vivo microCT imaging. J Bone Miner Res (2004) 1.85

The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches. Tissue Eng Part B Rev (2010) 1.81

Can platelet-rich plasma enhance tendon repair? A cell culture study. Am J Sports Med (2008) 1.78

A cam deformity is gradually acquired during skeletal maturation in adolescent and young male soccer players: a prospective study with minimum 2-year follow-up. Am J Sports Med (2014) 1.71

Fracture of an exeter stem 3 years after impaction allografting--a case report. Acta Orthop Scand (2002) 1.70

Does this patient have an instability of the shoulder or a labrum lesion? JAMA (2004) 1.59

Psychological factors affecting the outcome of total hip and knee arthroplasty: a systematic review. Semin Arthritis Rheum (2011) 1.57

Early identification of radiographic osteoarthritis of the hip using an active shape model to quantify changes in bone morphometric features: can hip shape tell us anything about the progression of osteoarthritis? Arthritis Rheum (2007) 1.57

Corticosteroid injections for greater trochanteric pain syndrome: a randomized controlled trial in primary care. Ann Fam Med (2011) 1.56

Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK). Ann Rheum Dis (2012) 1.48

Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. J Clin Oncol (2005) 1.48

Computer-assisted surgery is not more accurate or precise than conventional arthroscopic ACL reconstruction: a prospective randomized clinical trial. J Bone Joint Surg Am (2012) 1.43

Vitamin D status, bone mineral density, and the development of radiographic osteoarthritis of the knee: The Rotterdam Study. J Clin Rheumatol (2009) 1.42

One-year follow-up of platelet-rich plasma treatment in chronic Achilles tendinopathy: a double-blind randomized placebo-controlled trial. Am J Sports Med (2011) 1.41

Effects of iron oxide incorporation for long term cell tracking on MSC differentiation in vitro and in vivo. Biochem Biophys Res Commun (2008) 1.31

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models. BMC Musculoskelet Disord (2008) 1.30

Incidence and prevalence of upper-extremity musculoskeletal disorders. A systematic appraisal of the literature. BMC Musculoskelet Disord (2006) 1.26

In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells. BMC Musculoskelet Disord (2011) 1.26

The development of Cam-type deformity in adolescent and young male soccer players. Am J Sports Med (2012) 1.23

Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model. Arthritis Res Ther (2004) 1.20

Achilles tendinosis: changes in biochemical composition and collagen turnover rate. Am J Sports Med (2007) 1.19

Adverse effects of extra-articular corticosteroid injections: a systematic review. BMC Musculoskelet Disord (2010) 1.16

Identification of acid-sensing ion channels in bone. Biochem Biophys Res Commun (2005) 1.13

Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification. Tissue Eng Part A (2011) 1.12

Effects of Hypoxia on the Immunomodulatory Properties of Adipose Tissue-Derived Mesenchymal Stem cells. Front Immunol (2013) 1.11

The effect of high tibial osteotomy on the results of total knee arthroplasty: a matched case control study. BMC Musculoskelet Disord (2007) 1.10

Bone loss dynamics result in trabecular alignment in aging and ovariectomized rats. J Orthop Res (2006) 1.10

The whole leg radiograph: standing versus supine for determining axial alignment. Acta Orthop Scand (2003) 1.10

Opposite cortical fracture in high tibial osteotomy: lateral closing compared to the medial opening-wedge technique. Acta Orthop (2008) 1.09

Treatment of impingement syndrome: a systematic review of the effects on functional limitations and return to work. J Occup Rehabil (2006) 1.09

Intrinsic differentiation potential of adolescent human tendon tissue: an in-vitro cell differentiation study. BMC Musculoskelet Disord (2007) 1.07

Clinically translatable cell tracking and quantification by MRI in cartilage repair using superparamagnetic iron oxides. PLoS One (2011) 1.07

Chondrogenic priming of human bone marrow stromal cells: a better route to bone repair? Tissue Eng Part C Methods (2009) 1.06

Serum-free medium supplemented with high-concentration FGF2 for cell expansion culture of human ear chondrocytes promotes redifferentiation capacity. Tissue Eng (2002) 1.06

Cam impingement of the hip: a risk factor for hip osteoarthritis. Nat Rev Rheumatol (2013) 1.05

In vitro model to study chondrogenic differentiation in tendinopathy. Am J Sports Med (2009) 1.04

Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia. Pediatr Res (2003) 1.03

Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live fibulin-4 mice. Circ Cardiovasc Imaging (2010) 1.03

Hard tissue formation in a porous HA/TCP ceramic scaffold loaded with stromal cells derived from dental pulp and bone marrow. Tissue Eng Part A (2008) 1.03

Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study. BMC Musculoskelet Disord (2010) 1.03

Cationic Gd-DTPA liposomes for highly efficient labeling of mesenchymal stem cells and cell tracking with MRI. Cell Transplant (2011) 1.02

Osteoarthritis of the knee is associated with vertebral and nonvertebral fractures in the elderly: the Rotterdam Study. Arthritis Rheum (2003) 1.02

Alginate as a chondrocyte-delivery substance in combination with a non-woven scaffold for cartilage tissue engineering. Biomaterials (2002) 1.02

Total knee arthroplasty after high tibial osteotomy. A systematic review. BMC Musculoskelet Disord (2009) 1.01

Osteotomy for treating knee osteoarthritis. Cochrane Database Syst Rev (2014) 1.00

Microstructure and biomechanical characteristics of bone substitutes for trauma and orthopaedic surgery. BMC Musculoskelet Disord (2011) 1.00

Recovery of physical functioning after total hip arthroplasty: systematic review and meta-analysis of the literature. Phys Ther (2011) 0.99

High incidence and recurrence of shoulder and neck pain in nursing home employees was demonstrated during a 2-year follow-up. J Clin Epidemiol (2005) 0.98

Prognosis of hip pain in general practice: a prospective followup study. Arthritis Rheum (2007) 0.97

Infrapatellar fat pad of patients with end-stage osteoarthritis inhibits catabolic mediators in cartilage. Ann Rheum Dis (2011) 0.97

The dependence of the elastic properties of osteoporotic cancellous bone on volume fraction and fabric. J Biomech (2003) 0.97

Considerations on the use of ear chondrocytes as donor chondrocytes for cartilage tissue engineering. Biorheology (2004) 0.97

Long-term serotonin administration leads to higher bone mineral density, affects bone architecture, and leads to higher femoral bone stiffness in rats. J Cell Biochem (2006) 0.97

Work-related risk factors for the incidence and recurrence of shoulder and neck complaints among nursing-home and elderly-care workers. Scand J Work Environ Health (2004) 0.97

Analysis of mutations in B-RAF, N-RAS, and H-RAS genes in the differential diagnosis of Spitz nevus and spitzoid melanoma. Am J Surg Pathol (2005) 0.96

Multiplex ligation-dependent probe amplification for the detection of chromosomal gains and losses in formalin-fixed tissue. Diagn Mol Pathol (2005) 0.96

Selective laser melting-produced porous titanium scaffolds regenerate bone in critical size cortical bone defects. J Orthop Res (2012) 0.96