Published in PLoS One on August 15, 2011
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell (2013) 3.53
Mechanisms of protein delivery to melanosomes in pigment cells. Physiology (Bethesda) (2012) 1.19
Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site. J Biol Chem (2012) 1.07
Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet (2013) 1.03
Discovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-II. Small GTPases (2013) 0.98
The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway. Proc Natl Acad Sci U S A (2013) 0.94
30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology. Cell (2017) 0.92
TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane. PLoS One (2012) 0.89
Trs20 is required for TRAPP II assembly. Traffic (2013) 0.89
Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8. Cilia (2014) 0.87
miR379-410 cluster miRNAs regulate neurogenesis and neuronal migration by fine-tuning N-cadherin. EMBO J (2014) 0.82
Trs20 is required for TRAPP III complex assembly at the PAS and its function in autophagy. Traffic (2014) 0.81
NFκB signaling regulates embryonic and adult neurogenesis. Front Biol (Beijing) (2012) 0.77
Expression and function of NIK- and IKK2-binding protein (NIBP) in mouse enteric nervous system. Neurogastroenterol Motil (2013) 0.76
Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles. Sci Rep (2017) 0.75
Ayurvedic management of spondyloepiphyseal dysplasia tarda, a rare hereditary disorder. J Ayurveda Integr Med (2016) 0.75
Mutational analysis of the yeast TRAPP subunit Trs20p identifies roles in endocytic recycling and sporulation. PLoS One (2012) 0.75
Network organization of the human autophagy system. Nature (2010) 11.38
Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport. J Cell Biol (1995) 3.57
TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J (1998) 3.49
Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A (2010) 2.53
TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature (2007) 2.42
TRAPP stimulates guanine nucleotide exchange on Ypt1p. J Cell Biol (2000) 2.24
TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell (2001) 2.20
The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell (2006) 2.10
Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda. Nat Genet (1999) 1.80
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell (2003) 1.76
Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol (2005) 1.71
Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive mental retardation. Am J Hum Genet (2009) 1.58
A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly. Am J Hum Genet (2009) 1.55
mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell (2009) 1.55
TRAPP complexes in membrane traffic: convergence through a common Rab. Nat Rev Mol Cell Biol (2010) 1.50
TRAPP stably associates with the Golgi and is required for vesicle docking. EMBO J (2000) 1.50
NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation. J Biol Chem (2005) 1.47
Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem (2005) 1.42
The TRAPP complex: insights into its architecture and function. Traffic (2008) 1.40
Combination of linkage mapping and microarray-expression analysis identifies NF-kappaB signaling defect as a cause of autosomal-recessive mental retardation. Am J Hum Genet (2009) 1.38
mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. J Cell Biol (2006) 1.33
Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy (2005) 1.32
Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency. Gene Ther (1999) 1.31
TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. Traffic (2009) 1.18
Molecular architecture of the TRAPPII complex and implications for vesicle tethering. Nat Struct Mol Biol (2010) 1.16
Casein kinase I regulates membrane binding by ARF GAP1. Mol Biol Cell (2002) 1.01
X-linked spondyloepiphyseal dysplasia tarda: Novel and recurrent mutations in 13 European families. Hum Mutat (2004) 1.01
Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. J Cell Sci (2005) 0.99
SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1. PLoS One (2010) 0.99
Identification of the novel TRAPP associated protein Tca17. Traffic (2009) 0.98
Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and IKKbeta-binding protein. J Gen Virol (2010) 0.91
Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda. Biochem J (2009) 0.89
Loss of the SEDL gene product (Sedlin) causes X-linked spondyloepiphyseal dysplasia tarda: Identification of a molecular defect in a Japanese family. Am J Med Genet (2001) 0.88
Mutational analysis in X-linked spondyloepiphyseal dysplasia tarda. J Clin Endocrinol Metab (2001) 0.87
Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400). Eur J Hum Genet (2003) 0.83
X-linked spondyloepiphyseal dysplasia tarda: a novel SEDL mutation in a Jewish Ashkenazi family and clinical intervention considerations. Am J Med Genet A (2004) 0.78
The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1. PLoS One (2011) 0.78
A single nucleotide deletion of 293delT in SEDL gene causing spondyloepiphyseal dysplasia tarda in a four-generation Chinese family. Mutat Res (2003) 0.77
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet (2013) 3.87
TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature (2007) 2.42
Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Nat Cell Biol (2003) 1.81
An epididymis-specific beta-defensin is important for the initiation of sperm maturation. Nat Cell Biol (2004) 1.56
Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A (2003) 1.55
mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell (2009) 1.55
Cystic fibrosis transmembrane conductance regulator is vital to sperm fertilizing capacity and male fertility. Proc Natl Acad Sci U S A (2007) 1.44
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation. Free Radic Biol Med (2011) 1.34
Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy. Clin Cancer Res (2013) 1.26
Highly restricted expression of Cre recombinase in cerebellar Purkinje cells. Genesis (2004) 1.26
Identification of testis development and spermatogenesis-related genes in human and mouse testes using cDNA arrays. Mol Hum Reprod (2002) 1.12
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics. Chem Biol (2004) 1.05
Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori. Biochem J (2006) 1.04
Mechanosensitive gating of CFTR. Nat Cell Biol (2010) 1.03
Activation of the epithelial Na+ channel triggers prostaglandin E₂ release and production required for embryo implantation. Nat Med (2012) 1.01
STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta. Diabetes (2008) 1.01
Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2. J Physiol (2008) 1.01
Cl- is required for HCO3- entry necessary for sperm capacitation in guinea pig: involvement of a Cl-/HCO3- exchanger (SLC26A3) and CFTR. Biol Reprod (2008) 1.00
Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus. Antivir Ther (2005) 0.95
Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress. J Proteome Res (2015) 0.95
Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2. Hum Reprod (2012) 0.94
MicroRNAs and cystic fibrosis--an epigenetic perspective. Cell Biol Int (2011) 0.93
Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions. Development (2013) 0.92
CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. PLoS One (2013) 0.91
Involvement of CFTR in oviductal HCO3- secretion and its effect on soluble adenylate cyclase-dependent early embryo development. Hum Reprod (2010) 0.91
Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons. Invest Ophthalmol Vis Sci (2005) 0.91
Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. PLoS One (2011) 0.91
Inhibition of SARS coronavirus helicase by bismuth complexes. Chem Commun (Camb) (2007) 0.91
Estrogen-induced abnormally high cystic fibrosis transmembrane conductance regulator expression results in ovarian hyperstimulation syndrome. Mol Endocrinol (2005) 0.91
Regulation of male fertility by CFTR and implications in male infertility. Hum Reprod Update (2012) 0.90
Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer. Biochim Biophys Acta (2014) 0.90
Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer. Biochim Biophys Acta (2013) 0.90
Genome-wide haplotype association mapping in mice identifies a genetic variant in CER1 associated with BMD and fracture in southern Chinese women. J Bone Miner Res (2009) 0.90
A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori. J Biol Inorg Chem (2007) 0.90
Regulation of ion transport by 5-hydroxytryptamine in rat colon. Clin Exp Pharmacol Physiol (2004) 0.89
Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda. Biochem J (2009) 0.89
TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane. PLoS One (2012) 0.89
The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities. PLoS One (2012) 0.88
Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2. Biochemistry (2011) 0.88
The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus. PLoS One (2013) 0.88
Dedifferentiation-reprogrammed mesenchymal stem cells with improved therapeutic potential. Stem Cells (2011) 0.87
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer. Proc Natl Acad Sci U S A (2013) 0.87
Characterization of epithelial cell culture from human hydrosalpinges and effects of its conditioned medium on embryo development and sperm motility. Hum Reprod (2003) 0.87
CD9 is critical for cutaneous wound healing through JNK signaling. J Invest Dermatol (2011) 0.87
Overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) is associated with human cervical cancer malignancy, progression and prognosis. Gynecol Oncol (2012) 0.87
Trs130 participates in autophagy through GTPases Ypt31/32 in Saccharomyces cerevisiae. Traffic (2012) 0.87
New insights into the mechanisms underlying hydrosalpinx fluid formation and its adverse effect on IVF outcome. Hum Reprod Update (2002) 0.87
Differential expression and localization of CFTR and ENaC in mouse endometrium during pre-implantation. Cell Biol Int (2004) 0.87
CFTR negatively regulates cyclooxygenase-2-PGE(2) positive feedback loop in inflammation. J Cell Physiol (2012) 0.86
Autophagy is involved in adipogenic differentiation by repressesing proteasome-dependent PPARγ2 degradation. Am J Physiol Endocrinol Metab (2013) 0.86
The duality of LysU, a catalyst for both Ap4A and Ap3A formation. FEBS J (2006) 0.85
A novel biodegradable biliary stent in the normal duct hepaticojejunal anastomosis: an 18-month follow-up in a large animal model. J Gastrointest Surg (2007) 0.85
Regulation of smooth muscle contraction by the epithelium: role of prostaglandins. Physiology (Bethesda) (2011) 0.85
New insights into germ cell migration and survival/apoptosis in spermatogenesis: Lessons from CD147. Spermatogenesis (2012) 0.85
Regulatory mechanism underlying cyclic changes in mouse uterine bicarbonate secretion: role of estrogen. Reproduction (2010) 0.85
CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia. Hum Reprod (2012) 0.84
Functional asymmetry in the lysyl-tRNA synthetase explored by molecular dynamics, free energy calculations and experiment. BMC Struct Biol (2003) 0.84
Switching from bone marrow-derived neurons to epithelial cells through dedifferentiation and translineage redifferentiation. Cell Biol Int (2010) 0.84
Abnormally up-regulated cystic fibrosis transmembrane conductance regulator expression and uterine fluid accumulation contribute to Chlamydia trachomatis-induced female infertility. Fertil Steril (2010) 0.84
Abnormally enhanced cystic fibrosis transmembrane conductance regulator-mediated apoptosis in endometrial cells contributes to impaired embryo implantation in controlled ovarian hyperstimulation. Fertil Steril (2011) 0.83
Small colonic J-pouch improves colonic retention of liquids--randomized, controlled trial with scintigraphy. Dis Colon Rectum (2002) 0.83
Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability. J Cell Sci (2012) 0.83
Neuroprotective effects of Bak Foong Pill in 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine (MPTP)-induced Parkinson's disease model mice. Biol Pharm Bull (2004) 0.83
Differential inhibitory activities and stabilisation of DNA aptamers against the SARS coronavirus helicase. Chembiochem (2008) 0.83
CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Res (2012) 0.83
Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing. J Cell Physiol (2012) 0.83
Activation of GABAA receptor/Cl- channel and capacitation in rat spermatozoa: HCO3- and Cl- are essential. Syst Biol Reprod Med (2009) 0.82
Bak Foong Pills stimulate anion secretion across normal and cystic fibrosis pancreatic duct epithelia. Cell Biol Int (2002) 0.82
Involvement of calpain-I and microRNA34 in kanamycin-induced apoptosis of inner ear cells. Cell Biol Int (2010) 0.81
Cardiac glycosides block cancer growth through HIF-1α- and NF-κB-mediated Plk1. Carcinogenesis (2013) 0.81
Effects of Bak Foong Pill on blood coagulation and platelet aggregation. Biol Pharm Bull (2003) 0.81
Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection. J Obstet Gynaecol Res (2008) 0.81
Activation of apical CFTR and basolateral Ca(2+)-activated K+ channels by tetramethylpyrazine in Caco-2 cell line. Eur J Pharmacol (2005) 0.81
Bismuth complexes inhibit the SARS coronavirus. Angew Chem Int Ed Engl (2007) 0.81
Increased cystic fibrosis transmembrane conductance regulator (CFTR) expression in the human hydrosalpinx. Hum Reprod (2005) 0.81
Acrosome reaction in the cumulus oophorus revisited: involvement of a novel sperm-released factor NYD-SP8. Protein Cell (2011) 0.80
Establishment of a mouse primary co-culture of endometrial epithelial cells and peripheral blood leukocytes: effect on epithelial barrier function and leukocyte survival. Cell Biol Int (2006) 0.80
YWK-II protein as a novel G(o)-coupled receptor for Müllerian inhibiting substance in cell survival. J Cell Sci (2007) 0.80
A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis. J Cell Mol Med (2009) 0.80
Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK). PLoS One (2010) 0.80
Positional dependence of non-native polar mutations on folding of CFTR helical hairpins. Biochim Biophys Acta (2007) 0.80
Differential effects of Matrigel and its components on functional activity of CFTR and ENaC in mouse endometrial epithelial cells. Cell Biol Int (2003) 0.80
Long-term changes in hepatobiliary physiology after Roux-en-Y hepaticojejunostomy. J Surg Res (2007) 0.80
Traditional Chinese medicine Bak Foong Pills alters uterine quiescence - possible role in alleviation of dysmenorrhoeal symptoms. Cell Biol Int (2009) 0.80
The role of inducible nitric oxide synthase in gamete interaction and fertilization: a comparative study on knockout mice of three NOS isoforms. Cell Biol Int (2005) 0.80
CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis. Mol Hum Reprod (2011) 0.79
NYD-SP27, a novel intrinsic decapacitation factor in sperm. Asian J Androl (2009) 0.79
Immunization with Bin1b decreases sperm motility with compromised fertility in rats. Fertil Steril (2009) 0.79
Bak Foong Pills induce an analgesic effect by inhibiting nociception via the somatostatin pathway in mice. Cell Biol Int (2012) 0.79
Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis. Biochem Biophys Res Commun (2006) 0.79
Effective inhibition of xenografts of hepatocellular carcinoma (HepG2) by rapamycin and bevacizumab in an intrahepatic model. Mol Imaging Biol (2009) 0.79
Tertiary structure prediction of SARS coronavirus helicase. Biochem Biophys Res Commun (2006) 0.79
A protective mechanism against antibiotic-induced ototoxicity: role of prestin. PLoS One (2011) 0.78
CFTR is required for cellular entry and internalization of Chlamydia trachomatis. Cell Biol Int (2010) 0.78