PubRank

Gordon Ruthel

Author PubWeight™ 59.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature 2011 5.68
2 Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses. J Exp Med 2002 3.88
3 Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation. J Infect Dis 2003 3.15
4 Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proc Natl Acad Sci U S A 2005 2.35
5 In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding. Proc Natl Acad Sci U S A 2003 2.32
6 Ebola virus entry requires the host-programmed recognition of an intracellular receptor. EMBO J 2012 2.08
7 Dendritic cells endocytose Bacillus anthracis spores: implications for anthrax pathogenesis. J Immunol 2005 1.78
8 Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin. J Virol 2010 1.48
9 Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J Biol Chem 2006 1.47
10 Mechanical tension can specify axonal fate in hippocampal neurons. J Cell Biol 2002 1.46
11 Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis. PLoS Pathog 2013 1.28
12 Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. Antimicrob Agents Chemother 2009 1.26
13 Ebola virus uses clathrin-mediated endocytosis as an entry pathway. Virology 2010 1.23
14 Analysis of Ebola virus and VLP release using an immunocapture assay. J Virol Methods 2005 1.16
15 Ebola and Marburg virus-like particles activate human myeloid dendritic cells. Virology 2004 1.13
16 A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease. J Med Chem 2007 1.12
17 Anthrax lethal toxin impairs innate immune functions of alveolar macrophages and facilitates Bacillus anthracis survival. Infect Immun 2006 1.09
18 Nuclear export factor family protein participates in cytoplasmic mRNA trafficking. J Biol Chem 2005 1.09
19 Development of high-content imaging assays for lethal viral pathogens. J Biomol Screen 2010 1.06
20 Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by marburg and ebola viruses. J Virol 2006 1.05
21 Antiviral activity of a small-molecule inhibitor of filovirus infection. Antimicrob Agents Chemother 2010 1.02
22 Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules. PLoS One 2011 1.02
23 Primary cultures of embryonic chicken neurons for sensitive cell-based assay of botulinum neurotoxin: implications for therapeutic discovery. J Biomol Screen 2007 0.99
24 Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies. J Biomol Screen 2009 0.98
25 Human monocytes infected with Yersinia pestis express cell surface TLR9 and differentiate into dendritic cells. J Immunol 2004 0.97
26 A small molecule that mimics the BB-loop in the Toll interleukin-1 (IL-1) receptor domain of MyD88 attenuates staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice. J Biol Chem 2011 0.95
27 Reduced levels of protein tyrosine phosphatase CD45 protect mice from the lethal effects of Ebola virus infection. Cell Host Microbe 2009 0.94
28 Gaining ground: assays for therapeutics against botulinum neurotoxin. Trends Microbiol 2010 0.94
29 Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis. J Biol Chem 2009 0.94
30 NKp30-dependent cytolysis of filovirus-infected human dendritic cells. Cell Microbiol 2007 0.92
31 Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction. J Infect Dis 2007 0.91
32 Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway. Virology 2013 0.90
33 Pharmacophore Refinement Guides the Rational Design of Nanomolar-Range Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease. ACS Med Chem Lett 2010 0.89
34 Host IQGAP1 and Ebola virus VP40 interactions facilitate virus-like particle egress. J Virol 2013 0.89
35 MyD88-dependent pro-inflammatory cytokine response contributes to lethal toxicity of staphylococcal enterotoxin B in mice. Innate Immun 2010 0.85
36 CD44 Promotes intoxication by the clostridial iota-family toxins. PLoS One 2012 0.85
37 Pectin/zein beads for potential colon-specific drug delivery: synthesis and in vitro evaluation. Drug Deliv 2006 0.84
38 A host-oriented inhibitor of Junin Argentine hemorrhagic fever virus egress. J Virol 2014 0.83
39 Chemical genetic screening identifies critical pathways in anthrax lethal toxin-induced pathogenesis. Chem Biol 2007 0.83
40 In vitro inhibition of monkeypox virus production and spread by Interferon-β. Virol J 2012 0.81
41 Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin B by a synthetic dimeric BB-loop mimetic of MyD88. PLoS One 2012 0.81
42 Interleukin-15 increases vaccine efficacy through a mechanism linked to dendritic cell maturation and enhanced antibody titers. Clin Vaccine Immunol 2007 0.81
43 Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators. Infect Immun 2005 0.81
44 Efficacy of a capsule conjugate vaccine against inhalational anthrax in rabbits and monkeys. Vaccine 2011 0.81
45 In vitro intracellular trafficking of virulence antigen during infection by Yersinia pestis. PLoS One 2009 0.80
46 Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency. Botulinum J 2011 0.77