PubRank

James B McMahon

Author PubWeight™ 70.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol 2004 2.22
2 Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding. Structure 2006 2.16
3 Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp. J Biol Chem 2004 2.07
4 Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component. Proc Natl Acad Sci U S A 2009 1.87
5 Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat Struct Mol Biol 2009 1.84
6 Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Nucleic Acids Res 2005 1.75
7 Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening. J Natl Cancer Inst 2011 1.55
8 Neamphamide A, a new HIV-inhibitory depsipeptide from the Papua New Guinea marine sponge Neamphius huxleyi. J Nat Prod 2004 1.54
9 Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity. Structure 2010 1.33
10 A high-throughput cell-based assay for inhibitors of ABCG2 activity. J Biomol Screen 2006 1.26
11 Complete stereochemistry of neamphamide A and absolute configuration of the beta-methoxytyrosine residue in papuamide B. J Org Chem 2005 1.22
12 T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries. Proteomics 2006 1.20
13 Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin. Proteins 2007 1.20
14 New inhibitors of ABCG2 identified by high-throughput screening. Mol Cancer Ther 2007 1.18
15 Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression. J Biomol Screen 2006 1.17
16 Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. J Virol 2009 1.15
17 The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1. AIDS 2002 1.07
18 Botryllamides: natural product inhibitors of ABCG2. ACS Chem Biol 2009 1.05
19 Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium. Protein Expr Purif 2005 1.03
20 Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus. PLoS One 2013 1.03
21 A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1. J Biomol Screen 2006 1.02
22 The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors. J Mol Biol 2007 1.02
23 Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. J Nat Prod 2011 1.00
24 A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits". Mol Cancer Ther 2009 1.00
25 Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture. Protein Expr Purif 2005 0.98
26 Development of a high-throughput cell-based reporter assay to identify stabilizers of tumor suppressor Pdcd4. J Biomol Screen 2009 0.98
27 A cell-based high-throughput screen to identify synergistic TRAIL sensitizers. Cancer Immunol Immunother 2008 0.98
28 Isolation, structural elucidation, and absolute stereochemistry of enigmazole A, a cytotoxic phosphomacrolide from the Papua New Guinea marine sponge Cinachyrella enigmatica. J Am Chem Soc 2010 0.97
29 Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site. J Virol 2011 0.97
30 Monanchorin, a bicyclic alkaloid from the sponge Monanchora ungiculata. J Nat Prod 2004 0.95
31 A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H. J Nat Prod 2007 0.95
32 Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1. PLoS One 2012 0.95
33 Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4. J Nat Prod 2011 0.94
34 Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library. BMC Biotechnol 2007 0.93
35 Inhibition of thrombin-induced platelet aggregation using human single-chain Fv antibodies specific for TREM-like transcript-1. Thromb Haemost 2007 0.93
36 Potent anti-HIV activity of scytovirin domain 1 peptide. Peptides 2006 0.93
37 An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis. J Nat Prod 2007 0.91
38 Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. J Nat Prod 2009 0.90
39 Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers. J Nat Prod 2010 0.90
40 Chlorinated englerins with selective inhibition of renal cancer cell growth. J Nat Prod 2012 0.90
41 Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen. J Biomol Screen 2008 0.89
42 A capillary electrophoretic assay for ribonuclease H activity. Anal Biochem 2004 0.88
43 Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res 2011 0.88
44 The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells. Virology 2011 0.88
45 New candidaspongiolides, tedanolide analogues that selectively inhibit melanoma cell growth. Org Lett 2011 0.86
46 Identification and evaluation of soft coral diterpenes as inhibitors of HIF-2α induced gene expression. Bioorg Med Chem Lett 2011 0.83
47 HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis. J Nat Prod 2008 0.82
48 Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53. Bioorg Med Chem 2008 0.82
49 Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. Apoptosis 2012 0.82
50 Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera. J Nat Prod 2012 0.80
51 Natural products active in aberrant c-Kit signaling. Chem Biol Drug Des 2007 0.79
52 Inhibition of hypoxia inducible factor-2 transcription: isolation of active modulators from marine sponges. J Nat Prod 2012 0.79
53 Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. J Nat Prod 2011 0.78
54 Lack of a functional VHL gene product sensitizes renal cell carcinoma cells to the apoptotic effects of the protein synthesis inhibitor verrucarin A. Neoplasia 2012 0.78
55 High-throughput screening for identification of inhibitors of EpCAM-dependent growth of hepatocellular carcinoma cells. Chem Biol Drug Des 2013 0.78
56 Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima. J Nat Prod 2012 0.78
57 Growth inhibition of human colon carcinoma cells by sesquiterpenoids and tetralones of Zygogynum calothyrsum. J Nat Prod 2013 0.78
58 Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula. J Nat Prod 2011 0.77
59 High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41. J Biomol Screen 2002 0.77
60 Gymnangiamide, a cytotoxic pentapeptide from the marine hydroid Gymnangium regae. J Org Chem 2004 0.77
61 Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN. Virology 2013 0.77
62 Development of an image analysis screen for estrogen receptor alpha (ERα) ligands through measurement of nuclear translocation dynamics. J Steroid Biochem Mol Biol 2010 0.77
63 Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp. J Nat Prod 2002 0.77
64 Structural assignment of poecillastrins B and C, macrolide lactams from the deep-water Caribbean sponge Poecillastra species. J Nat Prod 2007 0.77
65 Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro. J Biomol Screen 2013 0.76
66 Isolation and characterization of anti-HIV peptides from Dorstenia contrajerva and Treculia obovoidea. FEBS Lett 2004 0.76
67 Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids. Bioorg Med Chem Lett 2010 0.76
68 Steroidal alkaloids from the marine sponge Corticium niger that inhibit growth of human colon carcinoma cells. J Nat Prod 2014 0.75
69 Isobutylhydroxyamides from the pericarp of Nepalese Zanthoxylum armatum inhibit NF1-defective tumor cell line growth. J Nat Prod 2012 0.75
70 Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. J Nat Prod 2011 0.75
71 Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett 2011 0.75
72 Caulibugulones A-F, novel cytotoxic isoquinoline quinones and iminoquinones from the marine bryozoan Caulibugula intermis. J Nat Prod 2004 0.75
73 Deguelins, Natural Product Modulators of NF1-Defective Astrocytoma Cell Growth Identified by High-Throughput Screening of Partially Purified Natural Product Extracts. J Nat Prod 2015 0.75
74 Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina. Org Lett 2017 0.75
75 Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold. J Org Chem 2016 0.75
76 New monoterpene glycosides and phenolic compounds from Distylium racemosum and their inhibitory activity against ribonuclease H. Bioorg Med Chem Lett 2011 0.75