Published in Blood on June 01, 1990
Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest (2002) 5.42
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am J Pathol (2005) 1.97
Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. J Exp Med (1990) 1.34
Bactericidal/permeability-increasing protein (BPI) is an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis. Clin Exp Immunol (1995) 1.24
Interference of Wegener's granulomatosis autoantibodies with neutrophil Proteinase 3 activity. Clin Exp Immunol (1992) 1.22
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Anti-myeloperoxidase autoantibodies react with native but not denatured myeloperoxidase. Clin Exp Immunol (1992) 1.17
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Relevance of classic anti-neutrophil cytoplasmic autoantibody (C-ANCA)-mediated inhibition of proteinase 3-alpha 1-antitrypsin complexation to disease activity in Wegener's granulomatosis. Clin Exp Immunol (1993) 1.04
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The pulmonary physician in critical care * illustrative case 3: pulmonary vasculitis. Thorax (2003) 0.88
B cell-mediated pathogenesis of ANCA-mediated vasculitis. Semin Immunopathol (2014) 0.85
Endothelial cells and renal epithelial cells do not express the Wegener's autoantigen, proteinase 3. Clin Exp Immunol (1995) 0.85
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Refractory Wegener's granulomatosis responds to tumor necrosis factor blockade. Wien Klin Wochenschr (2004) 0.82
Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice. Clin Exp Immunol (2004) 0.81
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A novel specificity of anticytoplasmic autoantibodies directed against eosinophil peroxidase. Clin Exp Immunol (1993) 0.79
Comparative aspects of murine proteinase 3. Rheumatol Int (2010) 0.78
Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1β secretion in response to anti-MPO antibodies. Sci Rep (2015) 0.78
Neutrophil Extracellular Traps Contain Selected Antigens of Anti-Neutrophil Cytoplasmic Antibodies. Front Immunol (2017) 0.78
Antineutrophil cytoplasmic antibodies in Bulgarian patients with rheumatoid arthritis: characterization and clinical associations. Rheumatol Int (2004) 0.77
Comparative effects of antilactoferrin antibodies and tumor necrosis factor on neutrophil adherence to matrix proteins. Clin Diagn Lab Immunol (1999) 0.77
Structural and functional characterization of elastases from horse neutrophils. Biochem J (1994) 0.76
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Theodore E. Woodward Award. Do ANCA cause small vessel vasculitis? Trans Am Clin Climatol Assoc (2001) 0.75
Identification of 4-Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH) as a Candidate Serum Autoantibody Target for Kawasaki Disease. PLoS One (2015) 0.75
Role of saliva proteinase 3 in dental caries. Int J Oral Sci (2015) 0.75
The antigenic significance and methods of detection of the anti-neutrophil cytoplasmic autoantibodies (ANCA). Postgrad Med J (1992) 0.75
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Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med (1988) 8.01
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Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci U S A (1990) 7.19
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell (1995) 4.47
Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci U S A (1995) 3.46
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Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature (1995) 3.23
Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest (1984) 2.88
Treatment of progressive membranous glomerulopathy. A randomized trial comparing cyclophosphamide and corticosteroids with corticosteroids alone. The Glomerular Disease Collaborative Network. Ann Intern Med (1992) 2.66
Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters. J Clin Invest (1988) 2.54
Clinical course of anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and systemic vasculitis. The Glomerular Disease Collaborative Network. Ann Intern Med (1990) 2.49
Anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and vasculitis. Am J Pathol (1989) 2.40
Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest (1979) 2.40
Neoantigen of the polymerized ninth component of complement. Characterization of a monoclonal antibody and immunohistochemical localization in renal disease. J Clin Invest (1983) 2.39
Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kidney Int (1992) 2.30
Antibodies against granule proteins activate neutrophils in vitro. J Leukoc Biol (1991) 2.14
Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol (1996) 2.08
Clinical and pathologic characteristics of focal segmental glomerulosclerosis pathologic variants. Kidney Int (2006) 2.06
Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity. Proc Natl Acad Sci U S A (1982) 1.99
Human fibronectin binding to staphylococcal surface protein and its relative inefficiency in promoting phagocytosis by human polymorphonuclear leukocytes, monocytes, and alveolar macrophages. Infect Immun (1981) 1.97
Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties. J Biol Chem (1991) 1.96
Treatment response and relapse in antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol (1996) 1.95
Antineutrophil cytoplasmic autoantibodies and associated diseases: a review. Am J Kidney Dis (1990) 1.95
Collapsing glomerulopathy: a clinically and pathologically distinct variant of focal segmental glomerulosclerosis. Kidney Int (1994) 1.91
The pathologic spectrum of pulmonary lesions in patients with anti-neutrophil cytoplasmic autoantibodies specific for anti-proteinase 3 and anti-myeloperoxidase. Am J Clin Pathol (1995) 1.91
ANCA small-vessel vasculitis. J Am Soc Nephrol (1997) 1.89
A review of therapeutic studies of idiopathic membranous glomerulopathy. Am J Kidney Dis (1995) 1.85
Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. J Clin Invest (2000) 1.84
Prevalence and pathologic features of sickle cell nephropathy and response to inhibition of angiotensin-converting enzyme. N Engl J Med (1992) 1.82
Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis. Kidney Int (2007) 1.77
C1q nephropathy: a distinct pathologic entity usually causing nephrotic syndrome. Am J Kidney Dis (1985) 1.64
Antineutrophil cytoplasmic antibodies and associated diseases: a review of the clinical and laboratory features. Kidney Int (2000) 1.64
Altered oxidative metabolic responses in vitro of alveolar macrophages from asymptomatic cigarette smokers. Am Rev Respir Dis (1981) 1.64
Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice. Kidney Int (2007) 1.64
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Cloning, genomic organization, chromosomal assignment and expression of a novel mosaic serine proteinase: epitheliasin. FEBS Lett (2000) 1.57
ANCA antigens, proteinase 3 and myeloperoxidase, are not expressed in endothelial cells. Kidney Int (2000) 1.53
Efficacy of treatment for unexplained infertility. Fertil Steril (1998) 1.48
Opsonic requirements for the uptake of Cryptococcus neoformans by human polymorphonuclear leukocytes and monocytes. J Infect Dis (1982) 1.47
Phagocytosis, bacterial killing, and metabolism by purified human lung phagocytes. J Infect Dis (1981) 1.46
Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages. J Clin Invest (1987) 1.43
Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane. Kidney Int (2001) 1.43
Dusts causing pneumoconiosis generate .OH and produce hemolysis by acting as Fenton catalysts. Arch Biochem Biophys (1989) 1.41
Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils. J Am Soc Nephrol (1997) 1.40
Alterations in leukocyte oxidative metabolism in cigarette smokers. Am Rev Respir Dis (1982) 1.36
Phagocytosis by polymorphonuclear leukocytes of Staphylococcus aureus and Pseudomonas aeruginosa adherent to plastic, agar, or glass. J Immunol Methods (1983) 1.36
Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. Am J Physiol (1992) 1.36
Silica exposure in anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and lupus nephritis. J Am Soc Nephrol (2001) 1.36
Human dipeptidyl-peptidase I. Gene characterization, localization, and expression. J Biol Chem (1997) 1.35
Peritoneal macrophages and opsonins: antibacterial defense in patients undergoing chronic peritoneal dialysis. J Infect Dis (1983) 1.35
Interleukin-8 delays spontaneous and tumor necrosis factor-alpha-mediated apoptosis of human neutrophils. Kidney Int (1998) 1.34
Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase. Am J Pathol (1996) 1.33
Localization of S protein and its relationship to the membrane attack complex of complement in renal tissue. Am J Pathol (1987) 1.33
Pulmonary inflammation due to oxygen toxicity: involvement of chemotactic factors and polymorphonuclear leukocytes. Am Rev Respir Dis (1981) 1.33
Clinical and pathologic features of fibrillary glomerulonephritis. Kidney Int (1992) 1.32
Monoclonal antibodies to human renal basement membranes: heterogenic and ontogenic changes. Kidney Int (1983) 1.31
Effect of tumor necrosis factor-alpha and interleukin-1 alpha on heme oxygenase-1 expression in human endothelial cells. Am J Physiol (1998) 1.31
The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice. J Immunol (1999) 1.30
Copper-dependent inflammation and nuclear factor-kappaB activation by particulate air pollution. Am J Respir Cell Mol Biol (1998) 1.30
Pathogenesis of the vascular and glomerular damage in ANCA-positive vasculitis. Nephrol Dial Transplant (1998) 1.28
Reactivity of anti-neutrophil cytoplasmic autoantibodies with HL-60 cells. Clin Immunol Immunopathol (1989) 1.28
Radioimmunoassay of the attack complex of complement in serum from patients with systemic lupus erythematosus. N Engl J Med (1985) 1.26
Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants. Am J Pathol (2001) 1.26
Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells. J Clin Invest (1992) 1.25
Pathogenesis of emphysema. Chest (1983) 1.22
Infections associated with subclavian Uldall catheters. Arch Intern Med (1983) 1.21
Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis. Hypertension (1997) 1.21
Pathologic differentiation between lupus and nonlupus membranous glomerulopathy. Kidney Int (1983) 1.20
Increased leucocyte oxidative metabolism in hyperlipoproteinaemia. Lancet (1982) 1.20
Lung phagocyte recruitment and metabolic alterations induced by cigarette smoke in humans and in hamsters. Am Rev Respir Dis (1982) 1.19
Reactivity of antineutrophil cytoplasmic autoantibodies with mononuclear phagocytes. J Leukoc Biol (1992) 1.19
Lung fibrosis and emphysema: divergent responses to a common injury? Science (1982) 1.18
Anti-myeloperoxidase autoantibodies react with native but not denatured myeloperoxidase. Clin Exp Immunol (1992) 1.17
Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation. J Immunol (1994) 1.17
Influence of subinhibitory concentrations of penicillin, cephalothin, and clindamycin on Staphylococcus aureus growth in human phagocytic cells. Antimicrob Agents Chemother (1982) 1.14
Lack of endothelial nitric oxide synthase aggravates murine accelerated anti-glomerular basement membrane glomerulonephritis. Am J Pathol (2000) 1.13