Opioid receptor blockade improves hypoglycemia-associated autonomic failure in type 1 diabetes mellitus.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMC 3205891)

Published in J Clin Endocrinol Metab on September 14, 2011

Authors

Septimiu Vele1, Sofiya Milman, Harry Shamoon, Ilan Gabriely

Author Affiliations

1: Department of Medicine, Albert Einstein College of Medicine, Belfer 702, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

Articles cited by this

Standards of medical care in diabetes--2011. Diabetes Care (2011) 21.94

Influences of glucose loading and of injected insulin on hepatic glucose output. Ann N Y Acad Sci (1959) 8.62

Hypoglycemia in diabetes. Diabetes Care (2003) 6.19

Epidemiology of severe hypoglycemia in the diabetes control and complications trial. The DCCT Research Group. Am J Med (1991) 5.46

The barrier of hypoglycemia in diabetes. Diabetes (2008) 4.50

Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes (1987) 2.95

Mechanisms of hypoglycemia-associated autonomic failure and its component syndromes in diabetes. Diabetes (2005) 2.86

Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia. J Clin Invest (1993) 2.35

Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes (1995) 2.30

Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest (1997) 2.16

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest (1994) 2.09

Long-term recovery from unawareness, deficient counterregulation and lack of cognitive dysfunction during hypoglycaemia, following institution of rational, intensive insulin therapy in IDDM. Diabetologia (1994) 1.34

Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis. Cell Mol Life Sci (2010) 1.27

Pharmacokinetics of naloxone in rats and in man: basis for its potency and short duration of action. Anesthesiology (1976) 1.26

Estimation of glucose turnover and recycling in rabbits using various [3H, 14C]glucose labels. Am J Physiol (1976) 1.21

Further defects in counterregulatory responses induced by recurrent hypoglycemia in IDDM. Diabetes (1992) 1.13

Pre- and postsynaptic actions of opioid and orphan opioid agonists in the rat arcuate nucleus and ventromedial hypothalamus in vitro. J Physiol (1999) 1.04

Substantial rise of plasma beta-endorphin levels after insulin-induced hypoglycemia in human subjects. J Clin Endocrinol Metab (1979) 1.03

mu-opioid receptor mRNA expression in identified hypothalamic neurons. J Comp Neurol (2005) 1.03

Opiate blockade enhances hypoglycemic counterregulation in normal and insulin-dependent diabetic subjects. Am J Physiol (1991) 0.96

Rostroventrolateral medullary neurons modulate glucose homeostasis in the rat. Am J Physiol Endocrinol Metab (2010) 0.96

Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure. Diabetes (2010) 0.96

Mediation of Endogenous beta-endorphin by Tetrandrine to Lower Plasma Glucose in Streptozotocin-induced Diabetic Rats. Evid Based Complement Alternat Med (2004) 0.93

Effect of antecedent hypoglycemia on cognitive function and on glycemic thresholds for counterregulatory hormone secretion in healthy humans. Diabetes Care (1994) 0.92

Hypoglycemia-associated autonomic failure is prevented by opioid receptor blockade. J Clin Endocrinol Metab (2009) 0.92

Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther (2003) 0.91

Adrenergic mediation of hypoglycemia-associated autonomic failure. Diabetes (2011) 0.89

Functional analysis of opioid receptor subtypes in the ventromedial hypothalamic nucleus of the rat. Eur J Pharmacol (1996) 0.89

Distribution of mu, delta, and kappa opioid receptors in the hypothalamus of the rat. Brain Res (1990) 0.89

Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro. Auton Neurosci (2001) 0.87

Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats. Horm Metab Res (2002) 0.86

Beta-endorphin inhibits hypoglycemia-induced gene expression of corticotropin-releasing factor in the rat hypothalamus. Endocrinology (1992) 0.84

Opioids suppress basal and nicotine-induced catecholamine secretion via a stabilizing effect on actin filaments. Endocrinology (2001) 0.83

[Detection of the pro-opiomelanocortin peptide fragments--beta-endorphin and ACTH--in the adrenals of rats and mice by immunohistochemistry]. Biull Eksp Biol Med (1986) 0.83

Evidence for the participation of endogenous opioids in the sympathoadrenal response to hypoglycaemia in man. Clin Endocrinol (Oxf) (1985) 0.82

Opioids inhibit dopamine secretion from PC12 rat pheochromocytoma cells in a naloxone-reversible manner. Life Sci (1996) 0.80

Comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques. Life Sci (1975) 0.79

Kappa1-opioid binding sites are the dominant opioid binding sites in surgical specimens of human pheochromocytomas and in a human pheochromocytoma (KAT45) cell line. Eur J Pharmacol (1999) 0.79

Articles by these authors

Hypoglycemia in diabetes. Diabetes Care (2003) 6.19

Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. Diabetes (2005) 4.81

Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity. J Clin Endocrinol Metab (2009) 2.04

Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci (2012) 1.76

Extreme longevity is associated with increased serum thyrotropin. J Clin Endocrinol Metab (2009) 1.66

Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. J Clin Endocrinol Metab (2007) 1.49

Plasma HDL levels highly correlate with cognitive function in exceptional longevity. J Gerontol A Biol Sci Med Sci (2002) 1.43

Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes. J Am Diet Assoc (2003) 1.22

Genetic studies reveal the role of the endocrine and metabolic systems in aging. J Clin Endocrinol Metab (2010) 1.13

Fructose improves the ability of hyperglycemia per se to regulate glucose production in type 2 diabetes. Diabetes (2002) 1.13

Hypoglycemia in diabetes: common, often unrecognized. Cleve Clin J Med (2004) 1.07

Aging is associated with resistance to effects of leptin on fat distribution and insulin action. J Gerontol A Biol Sci Med Sci (2002) 1.06

Developing a multidisciplinary model of comparative effectiveness research within a clinical and translational science award. Acad Med (2011) 1.03

Role of hepatic glycogen breakdown in defective counterregulation of hypoglycemia in intensively treated type 1 diabetes. Diabetes (2006) 0.99

Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects. Diabetes (2002) 0.98

GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia (2014) 0.97

Human cerebral blood flow and metabolism in acute insulin-induced hypoglycemia. J Cereb Blood Flow Metab (2005) 0.97

Obesity, fasting plasma insulin, and C-reactive protein levels in healthy children. Obes Res (2003) 0.93

Hypoglycemia-associated autonomic failure is prevented by opioid receptor blockade. J Clin Endocrinol Metab (2009) 0.92

Fructose amplifies counterregulatory responses to hypoglycemia in humans. Diabetes (2002) 0.86

Post-challenge hyperglycemia in older adults is associated with increased cardiovascular risk profile. J Clin Endocrinol Metab (2009) 0.84

Fasting plasma insulin modulates lipid levels and particle sizes in 2- to 3-year-old children. Obes Res (2003) 0.83

Fructose normalizes specific counterregulatory responses to hypoglycemia in patients with type 1 diabetes. Diabetes (2005) 0.82

Phenotypes and genotypes of high density lipoprotein cholesterol in exceptional longevity. Curr Vasc Pharmacol (2014) 0.82

Association of exceptional parental longevity and physical function in aging. Age (Dordr) (2014) 0.79

Opioid receptor blockade prevents exercise-associated autonomic failure in humans. Diabetes (2012) 0.77

Magnitude of exercise-induced β-endorphin response is associated with subsequent development of altered hypoglycemia counterregulation. J Clin Endocrinol Metab (2011) 0.76

Awakening from sleep and hypoglycemia in type 1 diabetes mellitus. PLoS Med (2007) 0.75

MEDULLARY THYROID CANCER THAT STAINS NEGATIVE FOR CA 19-9 HAS DECREASED METASTATIC POTENTIAL. Endocr Pract (2015) 0.75

Transforming research environments through institutional partnerships: creation of an academic home for clinical and translational research. Clin Transl Sci (2010) 0.75