Published in Chemistry on August 23, 2011
An animal model of adult T-cell leukemia: humanized mice with HTLV-1-specific immunity. Blood (2013) 1.47
Pericosines, antitumour metabolites from the sea hare-derived fungus Periconia byssoides. Structures and biological activities. Org Biomol Chem (2007) 1.18
Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance. J Biol Chem (2009) 1.13
Modulation of the cell division cycle by human papillomavirus type 18 E4. J Virol (2002) 1.09
Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis. Thromb Res (2008) 1.08
Micropatterning of cells using modulated magnetic fields. Langmuir (2005) 1.07
Membrane-proximal {alpha}/{beta} stalk interactions differentially regulate integrin activation. J Biol Chem (2005) 1.06
Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin VIP36. J Biol Chem (2007) 1.02
Double-chelation-assisted Rh-catalyzed intermolecular hydroacylation between salicylaldehydes and 1,4-penta- or 1,5-hexadienes. J Org Chem (2004) 0.97
Structural requirements for activation in alphaIIb beta3 integrin. J Biol Chem (2010) 0.92
Integration of human T-cell leukemia virus type 1 in genes of leukemia cells of patients with adult T-cell leukemia. Cancer Sci (2004) 0.92
Intracellular internalization mechanism of protein transfection reagents. Biol Pharm Bull (2012) 0.91
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II). Bioorg Med Chem (2005) 0.90
Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. Circulation (2002) 0.89
Gene mutation analysis and immunohistochemical study of beta-catenin in odontogenic tumors. Pathol Int (2006) 0.89
Re-Evaluation of the PBAN Receptor Molecule: Characterization of PBANR Variants Expressed in the Pheromone Glands of Moths. Front Endocrinol (Lausanne) (2012) 0.89
Comparative effects of pitavastatin and probucol on oxidative stress, Cu/Zn superoxide dismutase, PPAR-gamma, and aortic stiffness in hypercholesterolemia. Am J Physiol Heart Circ Physiol (2006) 0.88
Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells. Cancer Sci (2006) 0.88
Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients. Br J Clin Pharmacol (2010) 0.87
Diffusion-weighted imaging of retroperitoneal malignant peripheral nerve sheath tumor in a patient with neurofibromatosis type 1. Magn Reson Med Sci (2008) 0.86
Serum tri- and tetra-antennary N-glycan is a potential predictive biomarker for castration-resistant prostate cancer. Prostate (2014) 0.86
Absolute stereostructures of cell-adhesion inhibitors, peribysins A, E, F and G, produced by a sea hare-derived Periconia sp. J Antibiot (Tokyo) (2005) 0.86
Asymmetric Rh-catalyzed intermolecular hydroacylation of 1,5-hexadiene with salicylaldehyde. Chem Pharm Bull (Tokyo) (2009) 0.86
A 1H NMR-based metabolomics approach for mechanistic insight into acetaminophen-induced hepatotoxicity. Drug Metab Pharmacokinet (2011) 0.85
Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism. Org Biomol Chem (2003) 0.85
Design and efficient synthesis of 2 alpha-(omega-hydroxyalkoxy)-1 alpha,25-dihydroxyvitamin D3 Analogues, including 2-epi-ED-71 and their 20-epimers with HL-60 cell differentiation activity. J Org Chem (2004) 0.85
Design, synthesis, and biological activity of boronic acid-based histone deacetylase inhibitors. J Med Chem (2009) 0.85
Concentrations and distribution of mercury and other heavy metals in surface sediments of the Yatsushiro Sea including Minamata Bay, Japan. Bull Environ Contam Toxicol (2007) 0.85
Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients. J Pharm Sci (2011) 0.84
Variation in cytostatic constituents of a sponge-derived Gymnascella dankaliensis by manipulating the carbon source. J Nat Prod (2007) 0.84
Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells. Cancer Sci (2013) 0.83
Preparation of an active recombinant peptide of crustacean androgenic gland hormone. Peptides (2002) 0.83
Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-1. Retrovirology (2009) 0.83
Intracellular trafficking mechanism, from intracellular uptake to extracellular efflux, for phospholipid/cholesterol liposomes. Biomaterials (2012) 0.83
A flat squared conformation of an ascidiacyclamide derivative caused by chiral modification of an oxazoline residue. Biochem Biophys Res Commun (2002) 0.83
Up-regulation of Akt and eNOS induces vascular smooth muscle cell differentiation in hypertension in vivo. J Cardiovasc Pharmacol (2005) 0.83
Cyclo(-Cha-Oxz-D-Val-Thz-Ile-Oxz-D-Val-Thz-) N,N-dimethylacetamide dihydrate: a square form of cyclohexylalanine-incorporated ascidiacyclamide having the strongest cytotoxicity. Acta Crystallogr C (2003) 0.82
CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs. Drug Metab Dispos (2010) 0.82
Nitrile-promoted Rh-catalyzed intermolecular hydroacylation of olefins with salicylaldehyde. J Org Chem (2007) 0.82
Characterization of Bombyx mori nucleopolyhedrovirus orf68 gene that encodes a novel structural protein of budded virus. Virology (2002) 0.81
NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers. J Clin Biochem Nutr (2013) 0.81
Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3. Bioorg Med Chem Lett (2003) 0.81
Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains. J Biol Chem (2013) 0.81
Add-on therapy of EPA reduces oxidative stress and inhibits the progression of aortic stiffness in patients with coronary artery disease and statin therapy: a randomized controlled study. J Atheroscler Thromb (2011) 0.81
Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients. Drug Metab Pharmacokinet (2009) 0.81
Conformations of helical Aib peptides containing a pair of L-amino acid and D-amino acid. J Pept Sci (2012) 0.81
Cell-specific expression of enhanced green fluorescence protein under the control of neuropeptide gene promoters in the brain of the silkworm, Bombyx mori, using Bombyx mori nucleopolyhedrovirus-derived vectors. Insect Biochem Mol Biol (2003) 0.81
Effects of antipsychotic polypharmacy on side-effects and concurrent use of medications in schizophrenic outpatients. Psychiatry Clin Neurosci (2012) 0.81
Calcium antagonist reduces oxidative stress by upregulating Cu/Zn superoxide dismutase in stroke-prone spontaneously hypertensive rats. Hypertens Res (2004) 0.81
Controlling the helical screw sense of peptides with C-terminal L-valine. J Pept Sci (2010) 0.81
Ethnic differences of two non-synonymous single nucleotide polymorphisms in CDA gene. Drug Metab Pharmacokinet (2009) 0.81
Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy. Bioorg Med Chem Lett (2011) 0.80
Establishment of Sf9 Transformants Constitutively Expressing PBAN Receptor Variants: Application to Functional Evaluation. Front Endocrinol (Lausanne) (2012) 0.80
Genetic polymorphisms and haplotypes of por, encoding cytochrome p450 oxidoreductase, in a Japanese population. Drug Metab Pharmacokinet (2010) 0.80
(2S,2'R)-analogue of LG190178 is a major active isomer. Bioorg Med Chem Lett (2007) 0.80
Reduction of human T-cell leukemia virus type-1 infection in mice lacking nuclear factor-kappaB-inducing kinase. Cancer Sci (2008) 0.80
The genetic background as a determinant of human T-cell leukemia virus type 1 proviral load. Biochem Biophys Res Commun (2003) 0.80
Heme-mediated binding of α-casein to ferritin: evidence for preferential α-casein binding to ferrous iron. Biometals (2011) 0.79
Effects of angiotensin II type 1 receptor antagonist on smooth muscle cell phenotype in intramyocardial arteries from spontaneously hypertensive rats. Hypertens Res (2004) 0.79
Polyethylene glycol prevents in vitro aggregation of slightly negatively-charged liposomes induced by heparin in the presence of bivalent ions. Biol Pharm Bull (2012) 0.79
Characterization of tea cultivated at four different altitudes using 1H NMR analysis coupled with multivariate statistics. J Agric Food Chem (2011) 0.79
Effect of methyl substitution on the antioxidative property and genotoxicity of resveratrol. Chem Res Toxicol (2008) 0.79
Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubicin-bound block copolymers. Int J Pharm (2011) 0.79
Alterations in the detergent-induced membrane permeability and solubilization of saturated phosphatidylcholine/cholesterol liposomes: effects of poly(ethylene glycol)-conjugated lipid. Chem Pharm Bull (Tokyo) (2012) 0.79
The BRO proteins of Bombyx mori nucleopolyhedrovirus are nucleocytoplasmic shuttling proteins that utilize the CRM1-mediated nuclear export pathway. Virology (2006) 0.79
Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.78
Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma. Jpn J Clin Oncol (2013) 0.78
Fluorophotometric determination of hydrogen peroxide and other reactive oxygen species with fluorescein hydrazide (FH) and its crystal structure. Chem Pharm Bull (Tokyo) (2008) 0.78
Simultaneous determination of polyethylene glycol-conjugated liposome components by using reversed-phase high-performance liquid chromatography with UV and evaporative light scattering detection. AAPS PharmSciTech (2013) 0.78
Isolation and structural elucidation of cyclopentynafil and N-octylnortadalafil found in a dietary supplement. Chem Pharm Bull (Tokyo) (2009) 0.78
A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency. Thromb Haemost (2007) 0.78
Kinetic study of the electron-transfer oxidation of the phenolate anion of a vitamin E model by molecular oxygen generating superoxide anion in an aprotic medium. Org Biomol Chem (2003) 0.78
Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties. Bioorg Med Chem Lett (2008) 0.78
Studies of sex pheromone production under neuroendocrine control by analytical and morphological means in the oriental armyworm, Pseudaletia separata, Walker (Lepidoptera: Noctuidae). Gen Comp Endocrinol (2011) 0.77
Analysis of new biomarkers for cholangiocarcinoma. J Hepatobiliary Pancreat Sci (2014) 0.77
[A long-term survivor after relapsed acute myeloblastic leukemia with anthracycline dilated cardiomyopathy]. Gan To Kagaku Ryoho (2008) 0.77
Helical peptide-foldamers having a chiral five-membered ring amino acid with two azido functional groups. J Org Chem (2014) 0.77
Increasing the conformational stability by replacement of heme axial ligand in c-type cytochrome. FEBS Lett (2002) 0.77
Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant. Immunogenetics (2012) 0.77
Design and screening strategies for alpha-glucosidase inhibitors based on enzymological information. Curr Top Med Chem (2009) 0.77
Mucoepidermoid carcinoma of an adolescent epiglottis. Jpn J Radiol (2010) 0.77
Distal promoter regions are responsible for differential regulation of human orosomucoid-1 and -2 gene expression and acute phase responses. Biol Pharm Bull (2014) 0.77