Modification of hepatic iron metabolism induced by pravastatin during obstructive cholestasis in rats.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 21925516)

Published in Life Sci on September 10, 2011

Authors

Gabriela Kolouchova1, Eva Brcakova, Petra Hirsova, Jolana Cermanova, Leos Fuksa, Jaroslav Mokry, Petr Nachtigal, Hana Lastuvkova, Stanislav Micuda

Author Affiliations

1: Department of Pharmacology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Czech Republic.

Articles by these authors

The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia. J Histochem Cytochem (2008) 1.38

Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments. Int J Radiat Biol (2012) 1.07

Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines. Mol Cell Endocrinol (2008) 1.06

Dental pulp stem cells and their characterization. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub (2009) 0.96

Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis. Liver Int (2013) 0.96

Validation of nitrite and nitrate measurements in exhaled breath condensate. Respiration (2005) 0.95

Breast cancer and cancer stem cells: a mini-review. Tumori (2014) 0.94

Expression and transport activity of breast cancer resistance protein (Bcrp/Abcg2) in dually perfused rat placenta and HRP-1 cell line. J Pharmacol Exp Ther (2006) 0.92

Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics. Methods Mol Biol (2010) 0.91

Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo. Clin Exp Pharmacol Physiol (2006) 0.90

Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis. Stem Cells Dev (2010) 0.90

Atorvastatin has hypolipidemic and anti-inflammatory effects in apoE/LDL receptor-double-knockout mice. Life Sci (2008) 0.90

Selected metabolic parameters and the risk for uterine fibroids. Int J Gynaecol Obstet (2008) 0.88

Atorvastatin slows down the deterioration of inner ear function with age in mice. Neurosci Lett (2006) 0.87

Vimentin expression during altered spermatogenesis in rats. Acta Histochem (2005) 0.86

Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures. Toxicol Sci (2011) 0.84

Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol (2010) 0.84

Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways. J Pharmacol Exp Ther (2012) 0.84

Oxidative stress parameters in different systemic rheumatic diseases. J Pharm Pharmacol (2006) 0.83

Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions. Eur J Clin Pharmacol (2004) 0.82

A novel myoepithelial/progenitor cell marker in the breast? Virchows Arch (2007) 0.82

Proliferative potential and phenotypic analysis of long-term cultivated human granulosa cells initiated by addition of follicular fluid. J Assist Reprod Genet (2011) 0.81

Rhodanineacetic acid derivatives as potential drugs: preparation, hydrophobic properties and antifungal activity of (5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acids. Molecules (2009) 0.81

Atorvastatin Increases Endoglin, SMAD2, Phosphorylated SMAD2/3 and eNOS Expression in ApoE/LDLR Double Knockout Mice. J Atheroscler Thromb (2009) 0.81

The influence of simvastatin, atorvastatin and high-cholesterol diet on acetylcholinesterase activity, amyloid beta and cholesterol synthesis in rat brain. Steroids (2008) 0.80

The effects of lactoferrin in a rat model of catecholamine cardiotoxicity. Biometals (2008) 0.80

The novel iron chelator, 2-pyridylcarboxaldehyde 2-thiophenecarboxyl hydrazone, reduces catecholamine-mediated myocardial toxicity. Chem Res Toxicol (2009) 0.80

Dexamethasone reduces methotrexate biliary elimination and potentiates its hepatotoxicity in rats. Toxicology (2009) 0.80

Morphological and functional changes in p-glycoprotein during dexamethasone-induced hepatomegaly. Clin Exp Pharmacol Physiol (2007) 0.80

Epigallocatechin gallate enhances biliary cholesterol secretion in healthy rats and lowers plasma and liver cholesterol in ethinylestradiol-treated rats. Eur J Pharmacol (2012) 0.79

Synchronized activity of organic cation transporter 3 (Oct3/Slc22a3) and multidrug and toxin extrusion 1 (Mate1/Slc47a1) transporter in transplacental passage of MPP+ in rat. Toxicol Sci (2012) 0.79

Alteration of methotrexate biliary and renal elimination during extrahepatic and intrahepatic cholestasis in rats. Biol Pharm Bull (2009) 0.79

Cholesterol effects on endoglin and its downstream pathways in ApoE/LDLR double knockout mice. Circ J (2011) 0.79

The relationship between serum bilirubin and Crohn's disease. Inflamm Bowel Dis (2014) 0.79

Pravastatin modulates liver bile acid and cholesterol homeostasis in rats with chronic cholestasis. J Gastroenterol Hepatol (2011) 0.79

Methotrexate released in vitro from bone cement inhibits human stem cell proliferation in S/G2 phase. Int Orthop (2009) 0.79

Cell adhesion molecules and eNOS expression in aorta of normocholesterolemic mice with different predispositions to atherosclerosis. Heart Vessels (2014) 0.79

The anticancer activity of alpha-tomatine against mammary adenocarcinoma in mice. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub (2013) 0.78

Stem cells and the phenomena of plasticity and diversity: a limiting property of carcinogenesis. Stem Cells Dev (2008) 0.78

Zonation of multidrug resistance-associated protein 2 in rat liver after induction with dexamethasone. J Gastroenterol Hepatol (2007) 0.78

Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis. J Cell Mol Med (2015) 0.78

The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation. Int J Radiat Biol (2013) 0.78

Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats. Biopharm Drug Dispos (2008) 0.78

Cardiac biomarkers in a model of acute catecholamine cardiotoxicity. Hum Exp Toxicol (2009) 0.78

Endoglin as a possible marker of atorvastatin treatment benefit in atherosclerosis. Pharmacol Res (2011) 0.78

Organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter in the placenta and fetal tissues: expression profile and fetus protective role at different stages of gestation. Biol Reprod (2013) 0.78

Endoglin expression in hyper-cholesterolemia and after atorvastatin treatment in apoE-deficient mice. J Pharm Pharm Sci (2006) 0.78

Spirulina platensis and phycocyanobilin activate atheroprotective heme oxygenase-1: a possible implication for atherogenesis. Food Funct (2013) 0.77

Activation of TGF-β receptors and Smad proteins by atorvastatin is related to reduced atherogenesis in ApoE/LDLR double knockout mice. J Atheroscler Thromb (2011) 0.77

The effect of Mdr1 induction on the pharmacokinetics of rhodamine 123 in rats. Basic Clin Pharmacol Toxicol (2005) 0.77

High Levels of Soluble Endoglin Induce a Proinflammatory and Oxidative-Stress Phenotype Associated with Preserved NO-Dependent Vasodilatation in Aortas from Mice Fed a High-Fat Diet. J Vasc Res (2016) 0.77

Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2. Toxicology (2012) 0.76

P-glycoprotein function and expression during obstructive cholestasis in rats. Eur J Gastroenterol Hepatol (2008) 0.76

Chemical decellularization: a promising approach for preparation of extracellular matrix. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub (2013) 0.76

Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats. Shock (2014) 0.76

Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats. Pharmacol Res (2009) 0.76