Published in Hum Genet on September 29, 2011
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A multi-SNP locus-association method reveals a substantial fraction of the missing heritability. Am J Hum Genet (2012) 1.07
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Common DNA variants predict tall stature in Europeans. Hum Genet (2013) 0.87
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PIAS4 is associated with macro/microcephaly in the novel interstitial 19p13.3 microdeletion/microduplication syndrome. Eur J Hum Genet (2015) 0.81
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Targeted capture and massively parallel sequencing of 12 human exomes. Nature (2009) 33.96
Exome sequencing identifies the cause of a mendelian disorder. Nat Genet (2009) 32.06
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Many sequence variants affecting diversity of adult human height. Nat Genet (2008) 12.80
Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat Genet (2010) 12.63
Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet (2010) 9.53
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet (2009) 7.65
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet (2009) 4.24
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet (2010) 3.60
Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals. Nat Genet (2011) 2.74
Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height. Am J Hum Genet (2001) 2.50
Defects in chromosome congression and mitotic progression in KIF18A-deficient cells are partly mediated through impaired functions of CENP-E. Cell Cycle (2009) 1.62
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GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling. J Biol Chem (2009) 1.00
Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting. Hum Mol Genet (1999) 0.97
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet (2009) 7.65
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet (2011) 4.04
The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res (2012) 3.80
Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells (2005) 3.66
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J Clin Invest (2003) 3.02
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet (2008) 2.89
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Identification of new genetic risk variants for type 2 diabetes. PLoS Genet (2010) 2.62
Over- and under-expressed microRNAs in human colorectal cancer. Int J Oncol (2009) 2.34
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun (2013) 2.31
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. J Clin Invest (2003) 2.23
Planning the human variome project: the Spain report. Hum Mutat (2009) 2.22
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet (2004) 2.10
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
A Japanese Lung Cancer Registry study: prognosis of 13,010 resected lung cancers. J Thorac Oncol (2008) 2.01
Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents. Circ J (2014) 1.99
Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. Am J Cardiol (2003) 1.98
Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet (2011) 1.97
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer. PLoS Genet (2012) 1.91
The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med (2008) 1.87
The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet (2004) 1.86
Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. Am J Hum Genet (2010) 1.81
Tranilast attenuates myocardial fibrosis in association with suppression of monocyte/macrophage infiltration in DOCA/salt hypertensive rats. J Hypertens (2004) 1.79
Diagnosis and treatment of deep pulmonary laceration with intrathoracic hemorrhage from blunt trauma. Ann Thorac Surg (2010) 1.77
CD133+CD44+ population efficiently enriches colon cancer initiating cells. Ann Surg Oncol (2008) 1.76
Present status of anticoagulation treatment in Japanese patients with atrial fibrillation: a report from the J-RHYTHM Registry. Circ J (2011) 1.75
Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res (2002) 1.75
Remote triggering of deep earthquakes in the 2002 Tonga sequences. Nature (2003) 1.74
Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. Clin Cancer Res (2008) 1.73
A novel class of Pseudoautosomal region 1 deletions downstream of SHOX is associated with Leri-Weill dyschondrosteosis. Am J Hum Genet (2005) 1.67
Randomized, multicenter, warfarin-controlled phase II study of edoxaban in Japanese patients with non-valvular atrial fibrillation. Circ J (2012) 1.67
Exome sequencing is an efficient tool for genetic screening of Charcot-Marie-Tooth disease. Hum Mutat (2012) 1.65
Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II study). Europace (2010) 1.63
A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study. Breast Cancer Res (2012) 1.62
Biological and genetic characteristics of tumor-initiating cells in colon cancer. Ann Surg Oncol (2007) 1.62
Clinical significance of TROP2 expression in colorectal cancer. Clin Cancer Res (2006) 1.61
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci U S A (2010) 1.60
Copy number increase of 1p36.33 and mitochondrial genome amplification in Epstein-Barr virus-transformed lymphoblastoid cell lines. Cancer Genet Cytogenet (2007) 1.59
Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci. Arthritis Rheum (2011) 1.58
Optimal treatment strategy for patients with paroxysmal atrial fibrillation: J-RHYTHM Study. Circ J (2008) 1.57
CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status. Diabetes (2012) 1.56
Vagal activity modulates spontaneous augmentation of J-wave elevation in patients with idiopathic ventricular fibrillation. Heart Rhythm (2011) 1.56
CRTC3 links catecholamine signalling to energy balance. Nature (2010) 1.55
Association of common variations of 8q24 with the risk of prostate cancer in Koreans and a review of the Asian population. BJU Int (2012) 1.53
Identification of 15 loci influencing height in a Korean population. J Hum Genet (2009) 1.52
D-dimer level influences thromboembolic events in patients with atrial fibrillation. Int J Cardiol (2005) 1.51
Joint identification of multiple genetic variants via elastic-net variable selection in a genome-wide association analysis. Ann Hum Genet (2010) 1.51
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. Arthritis Rheum (2008) 1.51
Relation of left atrial blood stasis to clinical risk factors in atrial fibrillation. Int J Cardiol (2008) 1.49
Neuropilin 1 and neuropilin 2 co-expression is significantly correlated with increased vascularity and poor prognosis in nonsmall cell lung carcinoma. Cancer (2002) 1.48
Nonalcoholic fatty liver disease in 2 siblings with adult-onset type II citrullinemia. J Pediatr Gastroenterol Nutr (2010) 1.47
Validation of CHA₂DS₂-VASc and HAS-BLED scores in Japanese patients with nonvalvular atrial fibrillation: an analysis of the J-RHYTHM Registry. Circ J (2014) 1.47
A genome-wide association study of a coronary artery disease risk variant. J Hum Genet (2013) 1.46
Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men. Am J Clin Nutr (2011) 1.46
Microthoracoscopic one-port method for lung cancer. Ann Thorac Surg (2009) 1.46
Use of Warfarin in Elderly Patients With Non-Valvular Atrial Fibrillation - Subanalysis of the J-RHYTHM Registry. Circ J (2015) 1.45
Accumulation of risk factors enhances the prothrombotic state in atrial fibrillation. Int J Cardiol (2007) 1.44
A genome-wide association study of gestational diabetes mellitus in Korean women. Diabetes (2012) 1.41
Differing effects of adaptive servoventilation and continuous positive airway pressure on muscle sympathetic nerve activity in patients with heart failure. Circ J (2014) 1.41
Validation of Risk Scoring System Excluding Female Sex From CHA2DS2-VASc in Japanese Patients With Nonvalvular Atrial Fibrillation – Subanalysis of the J-RHYTHM Registry. Circ J (2015) 1.41
Target intensity of anticoagulation with warfarin in Japanese patients with valvular atrial fibrillation – subanalysis of the J-RHYTHM Registry. Circ J (2014) 1.40
Angiotensin-converting enzyme-gene polymorphism is associated with collagen I synthesis and QT dispersion in essential hypertension. J Hypertens (2003) 1.40
Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation. Hum Mol Genet (2003) 1.40
Imbalance of renal production between 5-hydroxytryptamine and dopamine in patients with essential hypertension complicated by microalbuminuria. Am J Hypertens (2012) 1.40
Enalapril preserves sinus node function in a canine atrial fibrillation model induced by rapid atrial pacing. J Cardiovasc Electrophysiol (2005) 1.39
Long-term treatment with low-dose, but not high-dose, guanethidine improves ventricular function and survival of rats with heart failure after myocardial infarction. J Am Coll Cardiol (2003) 1.39
Clinicopathological and prognostic significance of PDCD4 and microRNA-21 in human gastric cancer. Int J Oncol (2010) 1.39
Tripartite motif-containing 29 (TRIM29) is a novel marker for lymph node metastasis in gastric cancer. Ann Surg Oncol (2007) 1.38
Inappropriate secretion of antidiuretic hormone in a patient with chronic inflammatory demyelinating polyneuropathy. Intern Med (2005) 1.38
A computerized in-hospital alert system for thrombolysis in acute stroke. Stroke (2010) 1.35
Underdiagnosis and undertreatment of COPD in primary care settings. Respirology (2003) 1.33
Copy number variations in East-Asian population and their evolutionary and functional implications. Hum Mol Genet (2009) 1.33
Clinicopathologic significance of KIAA1199 overexpression in human gastric cancer. Ann Surg Oncol (2009) 1.31
Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice. J Hepatol (2005) 1.31
Cancer stem cells in human gastrointestinal cancers. Hum Cell (2006) 1.30
Inhibitory effect of a soluble transforming growth factor beta type II receptor on the activation of rat hepatic stellate cells in primary culture. J Hepatol (2003) 1.30
High incidence of PRSS1 and SPINK1 mutations in Korean children with acute recurrent and chronic pancreatitis. J Pediatr Gastroenterol Nutr (2011) 1.30
Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans. PLoS Genet (2013) 1.29
Frequent inactivation of SPARC by promoter hypermethylation in colon cancers. Int J Cancer (2007) 1.28
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation. Nat Med (2008) 1.27
Left atrial appendage function and abnormal hypercoagulability in patients with atrial flutter. Chest (2003) 1.27
High-density single-nucleotide polymorphism maps of the human genome. Genomics (2005) 1.27
Distribution and risk profile of paroxysmal, persistent, and permanent atrial fibrillation in routine clinical practice: insight from the real-life global survey evaluating patients with atrial fibrillation international registry. Circ Arrhythm Electrophysiol (2012) 1.26
The survival pathways phosphatidylinositol-3 kinase (PI3-K)/phosphoinositide-dependent protein kinase 1 (PDK1)/Akt modulate liver regeneration through hepatocyte size rather than proliferation. Hepatology (2009) 1.26
Long-term prognosis of probands with Brugada-pattern ST-elevation in leads V1-V3. Circ Arrhythm Electrophysiol (2009) 1.25
Molecular characterization of GDD1/TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia. Biochem Biophys Res Commun (2007) 1.25