Anesthetic Routines: The Anesthesiologist's Role in GI Recovery and Postoperative Ileus.

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Published in Adv Prev Med on December 29, 2010

Authors

John B Leslie1, Eugene R Viscusi, Joseph V Pergolizzi, Sunil J Panchal

Author Affiliations

1: Department of Anesthesiology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259-5404, USA.

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A clinical pathway to accelerate recovery after colonic resection. Ann Surg (2000) 3.04

Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motility. Aliment Pharmacol Ther (2004) 2.48

Postoperative ileus. Dig Dis Sci (1990) 2.48

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Acute pain management for opioid dependent patients. Anaesthesia (2006) 2.24

Does gum chewing ameliorate postoperative ileus? Results of a prospective, randomized, placebo-controlled trial. J Am Coll Surg (2006) 2.19

Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum (2004) 2.19

Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg (1998) 2.00

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The role of epidural anesthesia and analgesia in surgical practice. Ann Surg (2003) 1.65

Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis. Gastroenterology (1992) 1.62

Neuroimmune mechanisms in postoperative ileus. Gut (2009) 1.61

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Randomized controlled trial to examine the influence of thoracic epidural analgesia on postoperative ileus after laparoscopic sigmoid resection. Br J Surg (1999) 1.55

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Erythromycin and other macrolides as prokinetic agents. Gastroenterology (1993) 1.06

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