|
1
|
KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium.
|
Blood
|
2006
|
2.41
|
|
2
|
Dynamics and plasticity of Weibel-Palade bodies in endothelial cells.
|
Arterioscler Thromb Vasc Biol
|
2006
|
1.88
|
|
3
|
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.
|
J Allergy Clin Immunol
|
2011
|
1.60
|
|
4
|
Functional architecture of Weibel-Palade bodies.
|
Blood
|
2011
|
1.55
|
|
5
|
Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis.
|
Blood
|
2013
|
1.55
|
|
6
|
Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.
|
Blood
|
2013
|
1.49
|
|
7
|
The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells.
|
Blood
|
2012
|
1.46
|
|
8
|
The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura.
|
Thromb Haemost
|
2005
|
1.39
|
|
9
|
Biogenesis and exocytosis of Weibel-Palade bodies.
|
Histochem Cell Biol
|
2002
|
1.32
|
|
10
|
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF.
|
Blood
|
2009
|
1.27
|
|
11
|
Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
|
Blood
|
2013
|
1.18
|
|
12
|
Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP.
|
Thromb Haemost
|
2006
|
1.13
|
|
13
|
Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies.
|
Arterioscler Thromb Vasc Biol
|
2003
|
1.11
|
|
14
|
Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
|
Arterioscler Thromb Vasc Biol
|
2011
|
1.08
|
|
15
|
Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain.
|
Haematologica
|
2011
|
1.02
|
|
16
|
Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.
|
J Biol Chem
|
2013
|
1.01
|
|
17
|
Establishment of outgrowth endothelial cells from peripheral blood.
|
Nat Protoc
|
2012
|
1.01
|
|
18
|
IgG subclasses of anti-FVIII antibodies during immune tolerance induction in patients with hemophilia A.
|
Br J Haematol
|
2008
|
0.99
|
|
19
|
Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.
|
Blood
|
2008
|
0.99
|
|
20
|
Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells.
|
Blood
|
2008
|
0.99
|
|
21
|
Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura.
|
Haematologica
|
2011
|
0.99
|
|
22
|
Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells.
|
Haematologica
|
2009
|
0.94
|
|
23
|
Dynein-dynactin complex mediates protein kinase A-dependent clustering of Weibel-Palade bodies in endothelial cells.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.93
|
|
24
|
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.
|
Mol Cell Proteomics
|
2011
|
0.93
|
|
25
|
Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.
|
J Biol Chem
|
2003
|
0.92
|
|
26
|
Von Willebrand factor targets IL-8 to Weibel-Palade bodies in an endothelial cell line.
|
Exp Cell Res
|
2003
|
0.89
|
|
27
|
Immunobiology of inhibitor development in hemophilia A.
|
Semin Thromb Hemost
|
2003
|
0.89
|
|
28
|
Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease.
|
J Biol Chem
|
2011
|
0.89
|
|
29
|
Small GTP-binding protein Ral is involved in cAMP-mediated release of von Willebrand factor from endothelial cells.
|
Arterioscler Thromb Vasc Biol
|
2004
|
0.88
|
|
30
|
Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.
|
Blood
|
2012
|
0.88
|
|
31
|
Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.
|
Thromb Haemost
|
2006
|
0.87
|
|
32
|
The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies.
|
PLoS One
|
2012
|
0.87
|
|
33
|
Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies.
|
J Proteome Res
|
2012
|
0.86
|
|
34
|
The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells.
|
J Biol Chem
|
2012
|
0.84
|
|
35
|
Requirements for immune recognition and processing of factor VIII by antigen-presenting cells.
|
Blood Rev
|
2011
|
0.84
|
|
36
|
Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system.
|
Hum Gene Ther
|
2012
|
0.84
|
|
37
|
Two classes of germline genes both derived from the V(H)1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII.
|
Blood
|
2002
|
0.83
|
|
38
|
Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease.
|
Thromb Haemost
|
2006
|
0.83
|
|
39
|
Rational design of small molecules targeting the C2 domain of coagulation factor VIII.
|
Blood
|
2013
|
0.82
|
|
40
|
Effect of laminar shear stress on the distribution of Weibel-Palade bodies in endothelial cells.
|
Thromb Res
|
2012
|
0.80
|
|
41
|
Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.
|
Blood
|
2011
|
0.80
|
|
42
|
Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cells.
|
PLoS One
|
2011
|
0.80
|
|
43
|
Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII.
|
PLoS One
|
2013
|
0.80
|
|
44
|
Analysis of factor VIII inhibitors in a haemophilia A patient with an Arg593-->Cys mutation using phage display.
|
Br J Haematol
|
2002
|
0.79
|
|
45
|
Factor VIII inhibitor in a patient with mild haemophilia A and an Asn618-->Ser mutation responsive to immune tolerance induction and cyclophosphamide.
|
Br J Haematol
|
2002
|
0.78
|
|
46
|
Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.
|
Haematologica
|
2011
|
0.78
|
|
47
|
Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.
|
Thromb Haemost
|
2005
|
0.76
|
|
48
|
Evaluation of the haemostatic potential of factor VIII-heparin cofactor II hybrid proteins in a mouse model.
|
Br J Haematol
|
2003
|
0.76
|
|
49
|
Improving on nature: redesigning ADAMTS13.
|
Blood
|
2012
|
0.75
|
|
50
|
Getting rid of bad memory.
|
Blood
|
2011
|
0.75
|
|
51
|
Storage and secretion of naturally occurring von Willebrand factor A domain variants.
|
Br J Haematol
|
2014
|
0.75
|
|
52
|
Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship.
|
Haematologica
|
2007
|
0.75
|