Vadim Y Arshavsky

Author PubWeight™ 69.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 RGS expression rate-limits recovery of rod photoresponses. Neuron 2006 3.48
2 Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation. Neuron 2002 3.09
3 Beyond counting photons: trials and trends in vertebrate visual transduction. Neuron 2005 2.71
4 Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. Nature 2004 2.48
5 Light-driven translocation of signaling proteins in vertebrate photoreceptors. Trends Cell Biol 2006 2.36
6 Transducin translocation in rods is triggered by saturation of the GTPase-activating complex. J Neurosci 2007 2.09
7 RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia. Invest Ophthalmol Vis Sci 2003 2.00
8 Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin. J Neurosci 2006 1.95
9 R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. J Biol Chem 2005 1.93
10 Structure and function of the visual arrestin oligomer. EMBO J 2007 1.66
11 Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem 2003 1.60
12 Phosducin facilitates light-driven transducin translocation in rod photoreceptors. Evidence from the phosducin knockout mouse. J Biol Chem 2004 1.56
13 Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron 2005 1.54
14 The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J Neurosci 2003 1.51
15 The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors. J Cell Biol 2008 1.32
16 Specificity of G protein-RGS protein recognition is regulated by affinity adapters. Neuron 2003 1.30
17 Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia. Science 2009 1.29
18 Transducin gamma-subunit sets expression levels of alpha- and beta-subunits and is crucial for rod viability. J Neurosci 2008 1.26
19 Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors. J Biol Chem 2005 1.23
20 Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity. J Biol Chem 2002 1.14
21 Protein sorting, targeting and trafficking in photoreceptor cells. Prog Retin Eye Res 2013 1.13
22 Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration. Proc Natl Acad Sci U S A 2013 1.10
23 Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse. J Neurosci 2010 1.09
24 Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA. Neuron 2011 1.07
25 Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer. Biochemistry 2006 1.06
26 Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. Biochemistry 2009 1.04
27 Phosducin regulates the expression of transducin betagamma subunits in rod photoreceptors and does not contribute to phototransduction adaptation. J Gen Physiol 2007 1.03
28 Ubiquitylation of the transducin betagamma subunit complex. Regulation by phosducin. J Biol Chem 2002 1.02
29 Two temporal phases of light adaptation in retinal rods. J Gen Physiol 2002 1.01
30 Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells. Mol Cell Proteomics 2010 1.01
31 Kinetic mechanism of RGS9-1 potentiation by R9AP. Biochemistry 2006 0.99
32 Electrostatic and lipid anchor contributions to the interaction of transducin with membranes: mechanistic implications for activation and translocation. J Biol Chem 2008 0.99
33 Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light. J Neurosci 2010 0.99
34 Functional comparison of RGS9 splice isoforms in a living cell. Proc Natl Acad Sci U S A 2008 0.94
35 Biology and functions of the RGS9 isoforms. Prog Mol Biol Transl Sci 2009 0.93
36 A single valine residue plays an essential role in peripherin/rds targeting to photoreceptor outer segments. PLoS One 2013 0.92
37 CNG-modulin: a novel Ca-dependent modulator of ligand sensitivity in cone photoreceptor cGMP-gated ion channels. J Neurosci 2012 0.92
38 Noncatalytic domains of RGS9-1.Gbeta 5L play a decisive role in establishing its substrate specificity. J Biol Chem 2002 0.90
39 The relationship between slow photoresponse recovery rate and temporal resolution of vision. J Neurosci 2012 0.90
40 Direct allosteric regulation between the GAF domain and catalytic domain of photoreceptor phosphodiesterase PDE6. J Biol Chem 2008 0.90
41 Facilitative glucose transporter Glut1 is actively excluded from rod outer segments. J Cell Sci 2010 0.90
42 Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration. J Immunol 2010 0.89
43 Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration. J Proteome Res 2013 0.87
44 Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction. Bioconjug Chem 2005 0.87
45 Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina. Biochim Biophys Acta 2007 0.86
46 The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit. J Biol Chem 2006 0.86
47 Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors. J Neurosci 2011 0.85
48 Kinetic approaches to study the function of RGS9 isoforms. Methods Enzymol 2004 0.83
49 The identification of the inhibitory gamma-subunits of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase in non-retinal tissues: differential processing of mRNA transcripts. Genomics 2002 0.82
50 Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia. J Biol Chem 2012 0.80
51 Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions. Nat Struct Mol Biol 2011 0.79
52 Rapid and sensitive method for detection of Y402, H402, I62, and V62 variants of complement factor H in human plasma samples using mass spectrometry. Invest Ophthalmol Vis Sci 2008 0.79
53 RGS9 knockout causes a short delay in light responses of ON-bipolar cells. PLoS One 2011 0.79
54 Myosin III illuminates the mechanism of arrestin translocation. Neuron 2004 0.79
55 Phosphorylation of G protein-coupled receptor kinase 1 (GRK1) is regulated by light but independent of phototransduction in rod photoreceptors. J Biol Chem 2011 0.77
56 Introducing Kirill A. Martemyanov, the 2014 recipient of the Cogan Award. Invest Ophthalmol Vis Sci 2014 0.75