Biochemical regulation of sleep and sleep biomarkers.

Evaluating sleep and cognition in HIV. J Acquir Immune Defic Syndr (2013) 1.64

Salivary markers of inflammation in response to acute stress. Brain Behav Immun (2014) 1.06

Cytokine polymorphisms are associated with poor sleep maintenance in adults living with human immunodeficiency virus/acquired immunodeficiency syndrome. Sleep (2014) 0.89

The temporal structure of behaviour and sleep homeostasis. PLoS One (2012) 0.88

Fatigue is associated with poor sleep in people with multiple sclerosis and cognitive impairment. Mult Scler Int (2014) 0.87

Biomarkers: symptoms, survivorship, and quality of life. Semin Oncol Nurs (2012) 0.85

Sleep, recovery, and metaregulation: explaining the benefits of sleep. Nat Sci Sleep (2015) 0.83

The pathophysiology of insomnia. Chest (2015) 0.82

Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration. Am J Physiol Regul Integr Comp Physiol (2015) 0.79

Relationship of inflammatory markers and pain in patients with head and neck cancer prior to anticancer therapy. Braz J Med Biol Res (2014) 0.79

Genetic and immunologic aspects of sleep and sleep disorders. Chest (2013) 0.78

Homeostatic sleep pressure is the primary factor for activation of cortical nNOS/NK1 neurons. Neuropsychopharmacology (2014) 0.78

A review of sleep deprivation studies evaluating the brain transcriptome. Springerplus (2014) 0.77

Salivary biomarkers of physical fatigue as markers of sleep deprivation. J Clin Sleep Med (2013) 0.77

Effects of exercise on brain and peripheral inflammatory biomarkers induced by total sleep deprivation in rats. J Inflamm (Lond) (2015) 0.77

A case with anti-galactocerebroside antibody-positive Mycoplasma pneumoniae meningoencephalitis presenting secondary hypersomnia. Neurol Sci (2012) 0.76

Paradoxical sleep deprivation impairs mouse survival after infection with malaria parasites. Malar J (2015) 0.75

Interleukin-1 receptor (IL-1R) mediates epilepsy-induced sleep disruption. BMC Neurosci (2016) 0.75

The Physiological Role of Tumor Necrosis Factor in Human Immunity and Its Potential Implications in Spinal Manipulative Therapy: A Narrative Literature Review. J Chiropr Med (2016) 0.75

Slow-paced respiration therapy to treat symptoms in pulmonary arterial hypertension. Heart Lung (2016) 0.75

Towards a dynamic clamp for neurochemical modalities. Sensors (Basel) (2015) 0.75

Association of self-reported symptoms with serum levels of vitamin D and multivariate cytokine profile in healthy women. J Inflamm Res (2017) 0.75

Brainstem regulation of slow-wave-sleep. Curr Opin Neurobiol (2017) 0.75

Cytokine polymorphisms are associated with daytime napping in adults living with HIV. Sleep Med (2017) 0.75

Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med (2007) 11.62

Synaptic scaling mediated by glial TNF-alpha. Nature (2006) 6.76

Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med (2007) 4.23

IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol (2010) 3.27

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression. Endocrinology (2006) 2.82

Sleep as a fundamental property of neuronal assemblies. Nat Rev Neurosci (2008) 2.79

Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur J Pharmacol (2004) 2.60

Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist. J Clin Endocrinol Metab (2004) 2.11

Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. J Neurosci (2004) 2.09

Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J Immunol (2005) 2.09

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat. J Pharmacol Exp Ther (2006) 2.06

Extraction of sleep-promoting factor S from cerebrospinal fluid and from brains of sleep-deprived animals. J Neurophysiol (1975) 2.04

Gene expression in the brain across the sleep-waking cycle. Brain Res (2000) 1.96

Metabolic syndrome--neurotrophic hypothesis. Med Hypotheses (2005) 1.78

The role of cytokines in sleep regulation. Curr Pharm Des (2008) 1.73

Local functional state differences between rat cortical columns. Brain Res (2005) 1.64

Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem (2000) 1.63

Links between the innate immune system and sleep. J Allergy Clin Immunol (2005) 1.57

Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome. Obes Res (2005) 1.56

TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus. Neuron (2011) 1.54

Pro-inflammatory cytokines and their effects in the dentate gyrus. Prog Brain Res (2007) 1.54

Biochemical regulation of non-rapid-eye-movement sleep. Front Biosci (2003) 1.52

The composition of sleep-promoting factor isolated from human urine. J Biol Chem (1982) 1.46

Cytokines, stress and depressive illness: brain-immune interactions. Ann Med (2003) 1.44

Sleep-promoting effects of cerebrospinal fluid from sleep-deprived goats. Proc Natl Acad Sci U S A (1967) 1.30

Effects of interleukin-1 beta on sleep are mediated by the type I receptor. Am J Physiol (1998) 1.26

Mice lacking the TNF 55 kDa receptor fail to sleep more after TNFalpha treatment. J Neurosci (1997) 1.26

Tumour necrosis factor-alpha (-308) gene polymorphism in obstructive sleep apnoea-hypopnoea syndrome. Eur Respir J (2005) 1.21

Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Brain (2008) 1.19

Tumor necrosis factor alpha: activity dependent expression and promotion of cortical column sleep in rats. Neuroscience (2008) 1.18

Role of brain IL-1beta on fatigue after exercise-induced muscle damage. Am J Physiol Regul Integr Comp Physiol (2006) 1.17

SLEEP AND CYTOKINES. Sleep Med Clin (2007) 1.14

New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. J Neurosci (2008) 1.14

ATP and the purine type 2 X7 receptor affect sleep. J Appl Physiol (1985) (2010) 1.13

TNFalpha siRNA reduces brain TNF and EEG delta wave activity in rats. Brain Res (2007) 1.11

Endogenous sleep-promoting substances and sleep regulation. Physiol Rev (1989) 1.07

Spontaneous and influenza virus-induced sleep are altered in TNF-alpha double-receptor deficient mice. J Appl Physiol (1985) (2008) 1.07

The effect of interleukin-1 blockade on fatigue in rheumatoid arthritis--a pilot study. Rheumatol Int (2004) 1.07

Adenosine and sleep. Curr Neuropharmacol (2009) 1.05

Sleep-associated changes in interleukin-1beta mRNA in the brain. J Interferon Cytokine Res (1998) 1.05

Association between genetic variants of IL-1beta, IL-6 and TNF-alpha cytokines and cognitive performance in the elderly general population of the MEMO-study. Psychoneuroendocrinology (2007) 1.03

Sleep electroencephalogram delta-frequency amplitude, night plasma levels of tumor necrosis factor alpha, and human immunodeficiency virus infection. Proc Natl Acad Sci U S A (1995) 1.02

Diurnal variation of TNF alpha in the rat brain. Neuroreport (1997) 0.98

Intrapreoptic microinjection of TNF-alpha enhances non-REM sleep in rats. Brain Res (2002) 0.97

Comparative, behavioural and electrocortical effects of tumor necrosis factor-alpha and interleukin-1 microinjected into the locus coeruleus of rat. Life Sci (1997) 0.96

Interleukin-1beta enhances non-rapid eye movement sleep when microinjected into the dorsal raphe nucleus and inhibits serotonergic neurons in vitro. Eur J Neurosci (2003) 0.95

P2 purinergic receptor modulation of cytokine production. Purinergic Signal (2007) 0.93

Kindling stimuli delivered at different times in the sleep-wake cycle. Sleep (2004) 0.92

Diurnal variations of tumor necrosis factor alpha mRNA and alpha-tubulin mRNA in rat brain. Neuroimmunomodulation (1998) 0.90

The effect of surgical treatment of obstructive sleep apnea syndrome on the plasma TNF-alpha levels. Tohoku J Exp Med (2004) 0.90

Effects of total sleep deprivation in major depression: overnight improvement of mood is accompanied by increased pain sensitivity and augmented pain complaints. Psychosom Med (2007) 0.89

Clinical experience with soluble TNF p75 receptor in rheumatoid arthritis. Semin Arthritis Rheum (1999) 0.88

Corticotropin-releasing hormone involvement in stressor-induced alterations in sleep and in the regulation of waking. Adv Neuroimmunol (1995) 0.88

Enhancement of slow-wave sleep by tumor necrosis factor-alpha is mediated by cyclooxygenase-2 in rats. Neuroreport (1998) 0.88

[Neuromediators and hypnogenic factors]. Rev Neurol (Paris) (1984) 0.87

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome. Am J Hypertens (2005) 0.86

Ghrelin microinjection into forebrain sites induces wakefulness and feeding in rats. Am J Physiol Regul Integr Comp Physiol (2006) 1.88

Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity. J Neurochem (2006) 1.61

Links between the innate immune system and sleep. J Allergy Clin Immunol (2005) 1.57

Biochemical regulation of non-rapid-eye-movement sleep. Front Biosci (2003) 1.52

Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases. J Med Chem (2013) 1.49

Delta wave power: an independent sleep phenotype or epiphenomenon? J Clin Sleep Med (2011) 1.25

Circadian desynchronization of core body temperature and sleep stages in the rat. Proc Natl Acad Sci U S A (2007) 1.16

Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damage. Am J Physiol Regul Integr Comp Physiol (2007) 1.16

State-specific asymmetries in EEG slow wave activity induced by local application of TNFalpha. Brain Res (2004) 1.15

ATP and the purine type 2 X7 receptor affect sleep. J Appl Physiol (1985) (2010) 1.13

TNFalpha siRNA reduces brain TNF and EEG delta wave activity in rats. Brain Res (2007) 1.11

Sleep and innate immunity. Front Biosci (Schol Ed) (2011) 1.11

Intratracheal double-stranded RNA plus interferon-gamma: a model for analysis of the acute phase response to respiratory viral infections. Life Sci (2004) 1.10

Tumor necrosis factor alpha increases cytosolic calcium responses to AMPA and KCl in primary cultures of rat hippocampal neurons. Brain Res (2003) 1.09

Spontaneous and influenza virus-induced sleep are altered in TNF-alpha double-receptor deficient mice. J Appl Physiol (1985) (2008) 1.07

Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses. J Neurochem (2007) 1.05

Obestatin alters sleep in rats. Neurosci Lett (2006) 1.05

Spontaneous sleep in mice with targeted disruptions of neuronal or inducible nitric oxide synthase genes. Brain Res (2003) 1.05

Unilateral cortical application of interleukin-1beta (IL1beta) induces asymmetry in fos, IL1beta and nerve growth factor immunoreactivity: implications for sleep regulation. Brain Res (2006) 1.04

A network model for activity-dependent sleep regulation. J Theor Biol (2008) 1.04

Interleukin-1beta has a role in cerebral cortical state-dependent electroencephalographic slow-wave activity. Sleep (2005) 1.02

Diurnal effects of acute and chronic administration of ethanol on sleep in rats. Alcohol Clin Exp Res (2002) 1.02

State-dependent effects of light-dark cycle on somatosensory and visual cortex EEG in rats. Am J Physiol Regul Integr Comp Physiol (2005) 1.02

The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice. Proc Natl Acad Sci U S A (2009) 1.02

Brain distribution of cytokine mRNA induced by systemic administration of interleukin-1beta or tumor necrosis factor alpha. Brain Res (2006) 1.01

Circadian variation in swim performance. J Appl Physiol (1985) (2006) 1.00

GHRH and sleep. Sleep Med Rev (2004) 1.00

Ghrelin-induced sleep responses in ad libitum fed and food-restricted rats. Brain Res (2006) 0.99

Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice. Am J Physiol Regul Integr Comp Physiol (2009) 0.99

Involvement of cytokines in slow wave sleep. Prog Brain Res (2011) 0.98

Physiological markers of local sleep. Eur J Neurosci (2009) 0.98

Homer1a and 1bc levels in the rat somatosensory cortex vary with the time of day and sleep loss. Neurosci Lett (2004) 0.97

Cytokine mRNA induction by interleukin-1beta or tumor necrosis factor alpha in vitro and in vivo. Brain Res (2008) 0.97

Intrapreoptic microinjection of TNF-alpha enhances non-REM sleep in rats. Brain Res (2002) 0.97

5'-Ectonucleotidase-knockout mice lack non-REM sleep responses to sleep deprivation. Eur J Neurosci (2012) 0.97

Sleep loss changes microRNA levels in the brain: a possible mechanism for state-dependent translational regulation. Neurosci Lett (2007) 0.96

Unilateral cortical application of tumor necrosis factor alpha induces asymmetry in Fos- and interleukin-1beta-immunoreactive cells within the corticothalamic projection. Brain Res (2005) 0.95

Neural plasticity and the brain renin-angiotensin system. Neurosci Biobehav Rev (2002) 0.95

Whisker stimulation increases expression of nerve growth factor- and interleukin-1beta-immunoreactivity in the rat somatosensory cortex. Brain Res (2010) 0.94

Detection of mouse-adapted human influenza virus in the olfactory bulbs of mice within hours after intranasal infection. J Neurovirol (2007) 0.93

Rapid eye movement sleep is reduced in prolactin-deficient mice. J Neurosci (2005) 0.93

Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice. Am J Physiol Regul Integr Comp Physiol (2007) 0.93

MicroRNA 132 alters sleep and varies with time in brain. J Appl Physiol (1985) (2011) 0.92

Glutamate induces the expression and release of tumor necrosis factor-alpha in cultured hypothalamic cells. Brain Res (2005) 0.92

Influenza virus-induced glucocorticoid and hypothalamic and lung cytokine mRNA responses in dwarf lit/lit mice. Brain Behav Immun (2005) 0.92

Cannabinoid receptor 1-expressing neurons in the nucleus accumbens. Proc Natl Acad Sci U S A (2012) 0.92

A local, bottom-up perspective on sleep deprivation and neurobehavioral performance. Curr Top Med Chem (2011) 0.92

GHRH and IL1beta increase cytoplasmic Ca(2+) levels in cultured hypothalamic GABAergic neurons. Brain Res (2002) 0.90

Tolerance of chronic 90-minute time-in-bed restriction in older long sleepers. Sleep (2009) 0.90

Interferon type I receptor-deficient mice have altered disease symptoms in response to influenza virus. Brain Behav Immun (2006) 0.90

Sleep deprivation increases the activation of nuclear factor kappa B in lateral hypothalamic cells. Brain Res (2004) 0.90

Sleep and immune function: glial contributions and consequences of aging. Curr Opin Neurobiol (2013) 0.89

Attenuation of the influenza virus sickness behavior in mice deficient in Toll-like receptor 3. Brain Behav Immun (2009) 0.89

Sleep in mice with nonfunctional growth hormone-releasing hormone receptors. Am J Physiol Regul Integr Comp Physiol (2002) 0.89

Localized suppression of cortical growth hormone-releasing hormone receptors state-specifically attenuates electroencephalographic delta waves. J Neurosci (2010) 0.88

Influenza virus- and cytokine-immunoreactive cells in the murine olfactory and central autonomic nervous systems before and after illness onset. J Neuroimmunol (2009) 0.88

Influenza virus pathophysiology and brain invasion in mice with functional and dysfunctional Mx1 genes. Brain Behav Immun (2011) 0.88

Influenza virus-induced sleep responses in mice with targeted disruptions in neuronal or inducible nitric oxide synthases. J Appl Physiol (1985) (2004) 0.88

Vagotomy attenuates brain cytokines and sleep induced by peripherally administered tumor necrosis factor-α and lipopolysaccharide in mice. Sleep (2013) 0.87

Growth hormone-releasing hormone: cerebral cortical sleep-related EEG actions and expression. Am J Physiol Regul Integr Comp Physiol (2007) 0.87

Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice. Behav Brain Res (2004) 0.86

Sleep and body temperature responses in an acute viral infection model are altered in interferon type I receptor-deficient mice. Brain Behav Immun (2005) 0.86

REM sleep deprivation attenuates actin-binding protein cortactin: a link between sleep and hippocampal plasticity. Neurosci Lett (2006) 0.85

Humoral sleep regulation; interleukin-1 and tumor necrosis factor. Vitam Horm (2012) 0.85

Brain-specific interleukin-1 receptor accessory protein in sleep regulation. J Appl Physiol (1985) (2011) 0.84

Sleep loss alters synaptic and intrinsic neuronal properties in mouse prefrontal cortex. Brain Res (2011) 0.83

Sleep in spontaneous dwarf rats. Brain Res (2006) 0.82

MicroRNA 138, let-7b, and 125a inhibitors differentially alter sleep and EEG delta-wave activity in rats. J Appl Physiol (1985) (2012) 0.82

Sleep disturbances in the rotenone animal model of Parkinson disease. Brain Res (2005) 0.82

The role of nitric oxide synthases in the sleep responses to tumor necrosis factor-alpha. Brain Behav Immun (2004) 0.81

Time of day differences in IL1beta and TNFalpha mRNA levels in specific regions of the rat brain. Neurosci Lett (2003) 0.81

Lack of impairment in glucose tolerance: support for further investigation of sleep restriction in older long sleepers. J Sleep Res (2010) 0.80

Interleukin-8 promotes non-rapid eye movement sleep in rabbits and rats. J Sleep Res (2004) 0.80

Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochem Res (2011) 0.79

Panel discussion: current status of measuring sleepiness. J Clin Sleep Med (2011) 0.78

Different brain structures mediate drinking and sleep suppression elicited by the somatostatin analog, octreotide, in rats. Brain Res (2003) 0.78

The olfactory nerve has a role in the body temperature and brain cytokine responses to influenza virus. Brain Behav Immun (2009) 0.78

Ethanol-induced suppression of LTP can be attenuated with an angiotensin IV analog. Regul Pept (2003) 0.77

Synthetic ansamycins prepared by a ring-expanding Claisen rearrangement. Synthesis and biological evaluation of ring and conformational analogues of the Hsp90 molecular chaperone inhibitor geldanamycin. Org Biomol Chem (2007) 0.77

Alterations in EEG activity and sleep after influenza viral infection in GHRH receptor-deficient mice. J Appl Physiol (1985) (2003) 0.77

The anterolateral projections of the medial basal hypothalamus affect sleep. Am J Physiol Regul Integr Comp Physiol (2009) 0.77

A cyclooxygenase-2 inhibitor attenuates spontaneous and TNF-alpha-induced non-rapid eye movement sleep in rabbits. Am J Physiol Regul Integr Comp Physiol (2003) 0.77

Panel discussion: can there be a biomarker for sleepiness? J Clin Sleep Med (2011) 0.77

Habituation of the head-shake response induces changes in brain matrix metalloproteinases-3 (MMP-3) and -9. Behav Brain Res (2006) 0.77

Time of day differences in the number of cytokine-, neurotrophin- and NeuN-immunoreactive cells in the rat somatosensory or visual cortex. Brain Res (2010) 0.77

Olfactory bulb and hypothalamic acute-phase responses to influenza virus: effects of immunization. Neuroimmunomodulation (2013) 0.76

IL-6-trans-signalling increases rapid-eye-movement sleep in rats. Eur J Pharmacol (2009) 0.76

Bright light treatment for high-anxious young adults: a randomized controlled pilot study. Depress Anxiety (2011) 0.76

Neurotrophins 3 and 4 enhance non-rapid eye movement sleep in rabbits. Neurosci Lett (2003) 0.76

Local use-dependent sleep. Curr Top Med Chem (2011) 0.76

Energy homeostasis regulatory peptides in hibernating grizzly bears. Gen Comp Endocrinol (2010) 0.75

A hump-shaped relationship between isolation and abundance of Notonecta irrorata colonists in aquatic mesocosms. Ecology (2009) 0.75