Published in Pharm Res on October 19, 2011
Stability-enhanced hot-melt extruded amorphous solid dispersions via combinations of Soluplus® and HPMCAS-HF. AAPS PharmSciTech (2015) 0.91
Coating solid dispersions on microneedles via a molten dip-coating method: development and in vitro evaluation for transdermal delivery of a water-insoluble drug. J Pharm Sci (2014) 0.81
Hot Melt Extrusion: Development of an Amorphous Solid Dispersion for an Insoluble Drug from Mini-scale to Clinical Scale. AAPS PharmSciTech (2015) 0.80
Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica. Int J Nanomedicine (2012) 0.79
Porous starch: a novel carrier for solubility enhancement of carbamazepine. AAPS PharmSciTech (2013) 0.78
Application of carrier and plasticizer to improve the dissolution and bioavailability of poorly water-soluble baicalein by hot melt extrusion. AAPS PharmSciTech (2014) 0.78
Angelica gigas Nakai and Soluplus-Based Solid Formulations Prepared by Hot-Melting Extrusion: Oral Absorption Enhancing and Memory Ameliorating Effects. PLoS One (2015) 0.78
Exploring the cocrystallization potential of urea and benzamide. J Mol Model (2016) 0.77
The effects of polymer carrier, hot melt extrusion process and downstream processing parameters on the moisture sorption properties of amorphous solid dispersions. J Pharm Pharmacol (2015) 0.76
A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy. Int J Nanomedicine (2015) 0.75
Extrusion - back to the future: Using an established technique to reform automated chemical synthesis. Beilstein J Org Chem (2017) 0.75
Melt-Cast Noninvasive Ocular Inserts for Posterior Segment Drug Delivery. J Pharm Sci (2017) 0.75
Hydroxypropyl methylcellulose-based controlled release dosage by melt extrusion and 3D printing: Structure and drug release correlation. Carbohydr Polym (2017) 0.75
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
A human functional protein interaction network and its application to cancer data analysis. Genome Biol (2010) 4.73
The iPlant Collaborative: Cyberinfrastructure for Plant Biology. Front Plant Sci (2011) 4.16
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol (2012) 3.66
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Epidemiology of anesthesia-related mortality in the United States, 1999-2005. Anesthesiology (2009) 3.00
TransmiR: a transcription factor-microRNA regulation database. Nucleic Acids Res (2009) 2.80
Association between highly active antiretroviral therapy and hypertension in a large cohort of men followed from 1984 to 2003. AIDS (2005) 2.48
Contemporary epidemiology and characterization of newborn males with prune belly syndrome. Urology (2010) 2.30
Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood study. J Clin Endocrinol Metab (2011) 2.16
Gender assignment for newborns with 46XY cloacal exstrophy: a 6-year followup survey of pediatric urologists. J Urol (2011) 2.11
Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy. J Gastroenterol (2015) 2.01
Oxygen isotope anomaly observed in water vapor from Alert, Canada and the implication for the stratosphere. Proc Natl Acad Sci U S A (2013) 1.78
Bisphosphonates reduce local recurrence in extremity giant cell tumor of bone: a case-control study. Bone (2007) 1.77
Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimers Dement (2013) 1.77
Effect of perinatal antiretroviral drug exposure on hematologic values in HIV-uninfected children: An analysis of the women and infants transmission study. J Infect Dis (2006) 1.64
Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid. Ann Neurol (2013) 1.63
Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells. Mol Cell Biol (2005) 1.62
MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs. BMC Genomics (2012) 1.61
Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases. Bioinformatics (2010) 1.59
Shock wave lithotripsy vs ureteroscopy: variation in surgical management of kidney stones at freestanding children's hospitals. J Urol (2012) 1.53
Long-term incidence of urinary tract infection after ureteral reimplantation for primary vesicoureteral reflux. J Pediatr Urol (2012) 1.48
Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation. J Biol Chem (2010) 1.46
Risk factors for complications after esophageal cancer resection: a prospective population-based study in Sweden. Ann Surg (2006) 1.44
A comparative study of the cytotoxicity of silver-based dressings in monolayer cell, tissue explant, and animal models. Wound Repair Regen (2007) 1.44
Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiol Aging (2012) 1.43
Diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. Dermatol Surg (2012) 1.41
Durability of antireflux effect of ureteral reimplantation for primary vesicoureteral reflux: findings on long-term cystography. Urology (2012) 1.39
Rationales, design and recruitment of the Taizhou Longitudinal Study. BMC Public Health (2009) 1.39
Increased risk of hepatotoxicity in HIV-infected pregnant women receiving antiretroviral therapy independent of nevirapine exposure. AIDS (2009) 1.36
Hydrogen sulfide in the mammalian cardiovascular system. Antioxid Redox Signal (2012) 1.36
Subthreshold symptoms of depression in preadolescent girls are stable and predictive of depressive disorders. J Am Acad Child Adolesc Psychiatry (2008) 1.33
Hydrogen sulfide: neurophysiology and neuropathology. Antioxid Redox Signal (2011) 1.30
Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol Pharmacol (2008) 1.29
Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells. Proc Natl Acad Sci U S A (2007) 1.29
CD14(high)CD16(+) rather than CD14(low)CD16(+) monocytes correlate with disease progression in chronic HIV-infected patients. J Acquir Immune Defic Syndr (2009) 1.29
Potential impact of amyloid imaging on diagnosis and intended management in patients with progressive cognitive decline. Alzheimer Dis Assoc Disord (2013) 1.28
Cepred: predicting the co-expression patterns of the human intronic microRNAs with their host genes. PLoS One (2009) 1.27
Creation of the Chinese visible human data set. Anat Rec B New Anat (2003) 1.27
Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models. Aging Cell (2009) 1.22
Endogenous hydrogen sulfide in patients with COPD. Chest (2005) 1.22
Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease. Behav Brain Res (2010) 1.22
Metformin stimulates osteoprotegerin and reduces RANKL expression in osteoblasts and ovariectomized rats. J Cell Biochem (2011) 1.19
Familial neuralgia of occipital and intermedius nerves in a Chinese family. J Headache Pain (2011) 1.17
The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL. Blood (2006) 1.17
Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. J Proteome Res (2009) 1.17
The Chinese Visible Human (CVH) datasets incorporate technical and imaging advances on earlier digital humans. J Anat (2004) 1.16
Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B. J Biol Chem (2003) 1.16
Irradiation stability and cytotoxicity of gold nanoparticles for radiotherapy. Int J Nanomedicine (2009) 1.15
Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest. Eur J Contracept Reprod Health Care (2009) 1.12
A method for generation phage cocktail with great therapeutic potential. PLoS One (2012) 1.12
A spatial analysis of genetic structure of human populations in China reveals distinct difference between maternal and paternal lineages. Eur J Hum Genet (2008) 1.12
Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage-implications for the treatment of osteoporosis. Free Radic Biol Med (2011) 1.11
Two dimensional hard x-ray nanofocusing with crossed multilayer Laue lenses. Opt Express (2011) 1.11
Impact of oppositional defiant disorder dimensions on the temporal ordering of conduct problems and depression across childhood and adolescence in girls. J Child Psychol Psychiatry (2011) 1.10
Neutrophil count and the inflammation-based glasgow prognostic score predict survival in patients with advanced gastric cancer receiving first-line chemotherapy. Asian Pac J Cancer Prev (2014) 1.10
Predictive value of serum CEA, CA19-9 and CA72.4 in early diagnosis of recurrence after radical resection of gastric cancer. Hepatogastroenterology (2012) 1.09
Depression begets depression: comparing the predictive utility of depression and anxiety symptoms to later depression. J Child Psychol Psychiatry (2009) 1.08
Hypertrophic response and keloid diathesis: two very different forms of scar. Plast Reconstr Surg (2005) 1.07
Applications of diffusion-weighted MRI in thoracic spinal cord injury without radiographic abnormality. Int Orthop (2006) 1.07
LysGH15, a novel bacteriophage lysin, protects a murine bacteremia model efficiently against lethal methicillin-resistant Staphylococcus aureus infection. J Clin Microbiol (2010) 1.07
Antimicrobial activity and the mechanism of silver nanoparticle thermosensitive gel. Int J Nanomedicine (2011) 1.06
Increased incidence of asthma in HIV-infected children treated with highly active antiretroviral therapy in the National Institutes of Health Women and Infants Transmission Study. J Allergy Clin Immunol (2008) 1.05
Safety of influenza vaccine administration in egg-allergic patients. Pediatrics (2010) 1.04
Morbidity and mortality during the first two years of life among uninfected children born to human immunodeficiency virus type 1-infected women: the women and infants transmission study. Pediatr Infect Dis J (2005) 1.04
Population pharmacokinetic modeling of ustekinumab, a human monoclonal antibody targeting IL-12/23p40, in patients with moderate to severe plaque psoriasis. J Clin Pharmacol (2009) 1.03
The combination of green tea and tamoxifen is effective against breast cancer. Carcinogenesis (2006) 1.03
The molecular recognition of kink-turn structure by the L7Ae class of proteins. RNA (2013) 1.02
Influence of severity of anemia on clinical findings in infants with sickle cell anemia: analyses from the BABY HUG study. Pediatr Blood Cancer (2011) 1.02
DNA methylation in oocytes and liver of female mice and their offspring: effects of high-fat-diet-induced obesity. Environ Health Perspect (2013) 1.00
Lack of increased hepatotoxicity in HIV-infected pregnant women receiving nevirapine compared with other antiretrovirals. AIDS (2010) 1.00
ASEB: a web server for KAT-specific acetylation site prediction. Nucleic Acids Res (2012) 0.99
SOD1, ANG, TARDBP and FUS mutations in amyotrophic lateral sclerosis: a United States clinical testing lab experience. Amyotroph Lateral Scler (2012) 0.99
Whole-body diffusion-weighted imaging vs. FDG-PET for the detection of non-small-cell lung cancer. How do they measure up? Magn Reson Imaging (2010) 0.98
Nitroxyl inhibits breast tumor growth and angiogenesis. Int J Cancer (2008) 0.98
Comparison of the anti-tumor effects of denosumab and zoledronic acid on the neoplastic stromal cells of giant cell tumor of bone. Connect Tissue Res (2013) 0.97
Maternal neutralizing antibody and transmission of hepatitis C virus to infants. J Infect Dis (2008) 0.97
Site-specific proteomics approach for study protein S-nitrosylation. Anal Chem (2010) 0.97
Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. Neurosci Lett (2012) 0.97
Different fates of oocytes with DNA double-strand breaks in vitro and in vivo. Cell Cycle (2014) 0.96
Associations between 45T/G polymorphism of the adiponectin gene and plasma adiponectin levels with type 2 diabetes. Clin Exp Pharmacol Physiol (2007) 0.96
The high prevalence of knee osteoarthritis in a rural Chinese population: the Wuchuan osteoarthritis study. Arthritis Rheum (2009) 0.96
Effects of desferoxamine on retinal and visual function. Arch Ophthalmol (2007) 0.96
Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis. Arthritis Res Ther (2011) 0.96
Notch signaling is involved in ovarian follicle development by regulating granulosa cell proliferation. Endocrinology (2011) 0.95
Apoptosis of activated CD4+ and CD8+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction. Virology (2005) 0.95
Characterization and prediction of lysine (K)-acetyl-transferase specific acetylation sites. Mol Cell Proteomics (2011) 0.95
Hepatitis C virus coinfection and HIV load, CD4+ cell percentage, and clinical progression to AIDS or death among HIV-infected women: Women and Infants Transmission Study. Clin Infect Dis (2005) 0.95
Randomized controlled trial of minimally invasive surgery using acellular dermal matrix for complex anorectal fistula. World J Gastroenterol (2010) 0.94
Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates. J Neuropathol Exp Neurol (2014) 0.94
Complete genome sequence of Staphylococcus aureus bacteriophage GH15. J Virol (2012) 0.94
Quality of life in children with vesicoureteral reflux as perceived by children and parents. J Pediatr Urol (2011) 0.94
Potential of a suite of robot/computer-assisted motivating systems for personalized, home-based, stroke rehabilitation. J Neuroeng Rehabil (2007) 0.94
Polymorphic variations in manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and catalase (CAT) contribute to elevated plasma triglyceride levels in Chinese patients with type 2 diabetes or diabetic cardiovascular disease. Mol Cell Biochem (2011) 0.94
Persistent homology for the quantitative prediction of fullerene stability. J Comput Chem (2014) 0.93
Evaluating performance of local case-mix system by international comparison: a case study in Beijing, China. Int J Health Plann Manage (2012) 0.93
Dantrolene: effects on abnormal intracellular Ca(2+) handling and inotropy in postinfarcted rat myocardium. Eur J Pharmacol (2003) 0.92
Capitation combined with pay-for-performance improves antibiotic prescribing practices in rural China. Health Aff (Millwood) (2014) 0.92
Cyclooxygenase inhibitors in urinary bladder cancer: in vitro and in vivo effects. Mol Cancer Ther (2006) 0.91