|
1
|
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.
|
Nature
|
2011
|
3.53
|
|
2
|
Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.
|
Nat Genet
|
2005
|
2.92
|
|
3
|
In silico analysis of missense substitutions using sequence-alignment based methods.
|
Hum Mutat
|
2008
|
2.73
|
|
4
|
Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer.
|
Am J Hum Genet
|
2009
|
2.02
|
|
5
|
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.
|
JAMA
|
2011
|
1.85
|
|
6
|
Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus.
|
BMC Genet
|
2009
|
1.63
|
|
7
|
Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study.
|
Breast Cancer Res
|
2011
|
1.45
|
|
8
|
Classification of missense substitutions in the BRCA genes: a database dedicated to Ex-UVs.
|
Hum Mutat
|
2011
|
1.31
|
|
9
|
Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.
|
Breast Cancer Res
|
2008
|
1.28
|
|
10
|
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.
|
Carcinogenesis
|
2008
|
1.11
|
|
11
|
Polymorphisms in the initiators of RET (rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma.
|
J Clin Endocrinol Metab
|
2005
|
1.11
|
|
12
|
Description and validation of high-throughput simultaneous genotyping and mutation scanning by high-resolution melting curve analysis.
|
Hum Mutat
|
2009
|
1.08
|
|
13
|
Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.
|
Breast Cancer Res
|
2005
|
1.04
|
|
14
|
Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation.
|
Int J Cancer
|
2013
|
1.02
|
|
15
|
Common variants in RB1 gene and risk of invasive ovarian cancer.
|
Cancer Res
|
2006
|
1.01
|
|
16
|
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.
|
Breast Cancer Res
|
2014
|
1.00
|
|
17
|
Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas.
|
Mol Oncol
|
2008
|
1.00
|
|
18
|
Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States.
|
PLoS One
|
2013
|
0.94
|
|
19
|
An association study of 22 candidate genes in psoriasis families reveals shared genetic factors with other autoimmune and skin disorders.
|
J Invest Dermatol
|
2009
|
0.94
|
|
20
|
RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study.
|
PLoS One
|
2012
|
0.93
|
|
21
|
COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration.
|
Breast Cancer Res
|
2013
|
0.90
|
|
22
|
Allelic loss on chromosomes 2q21 and 19p 13.2 in oxyphilic thyroid tumors.
|
Int J Cancer
|
2004
|
0.90
|
|
23
|
The FOXE1 locus is a major genetic determinant for familial nonmedullary thyroid carcinoma.
|
Int J Cancer
|
2013
|
0.90
|
|
24
|
New founder germline mutations of CDKN2A in melanoma-prone families and multiple primary melanoma development in a patient receiving levodopa treatment.
|
Genes Chromosomes Cancer
|
2007
|
0.88
|
|
25
|
Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.
|
Int J Cancer
|
2014
|
0.82
|
|
26
|
Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma.
|
J Clin Endocrinol Metab
|
2004
|
0.82
|
|
27
|
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.
|
BMC Cancer
|
2005
|
0.81
|
|
28
|
Impact of polymorphic variation at 7p15.3, 3p22.1 and 2p23.3 loci on risk of multiple myeloma.
|
Br J Haematol
|
2012
|
0.78
|
|
29
|
[MITF: a genetic key to melanoma and renal cell carcinoma?].
|
Med Sci (Paris)
|
2012
|
0.78
|
|
30
|
Comprehensive investigation of genetic variation in the 8q24 region and multiple myeloma risk in the IMMEnSE consortium.
|
Br J Haematol
|
2012
|
0.78
|
|
31
|
Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2.
|
BMC Med Genomics
|
2011
|
0.77
|
|
32
|
Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review).
|
Int J Oncol
|
2011
|
0.77
|
|
33
|
Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.
|
Cancer Epidemiol Biomarkers Prev
|
2014
|
0.77
|
|
34
|
Polymorphisms in regulators of xenobiotic transport and metabolism genes PXR and CAR do not affect multiple myeloma risk: a case-control study in the context of the IMMEnSE consortium.
|
J Hum Genet
|
2013
|
0.76
|
|
35
|
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.
|
J Natl Cancer Inst
|
2017
|
0.75
|
|
36
|
Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.
|
Nature
|
2015
|
0.75
|
|
37
|
A Greek family with a follicular variant of familial papillary thyroid carcinoma: TCO, MNG1, fPTC/PRN, and NMTC1 excluded as susceptibility loci.
|
Thyroid
|
2005
|
0.75
|