PubRank

Michael E Boulton

Author PubWeight™ 55.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function. Hum Mol Genet 2007 2.05
2 Mitochondrial DNA damage and its potential role in retinal degeneration. Prog Retin Eye Res 2008 1.96
3 Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock. J Exp Med 2009 1.68
4 Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med 2012 1.59
5 Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics 2008 1.50
6 Intraretinal leakage and oxidation of LDL in diabetic retinopathy. Invest Ophthalmol Vis Sci 2008 1.42
7 Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy 2013 1.34
8 Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res 2009 1.31
9 The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Invest Ophthalmol Vis Sci 2008 1.28
10 Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration. Invest Ophthalmol Vis Sci 2011 1.20
11 The importance of mitochondria in age-related and inherited eye disorders. Ophthalmic Res 2010 1.13
12 Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction. Proc Natl Acad Sci U S A 2013 1.07
13 Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair. Mol Ther 2009 1.05
14 β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment. EMBO Mol Med 2012 1.05
15 PEDF regulates vascular permeability by a γ-secretase-mediated pathway. PLoS One 2011 1.05
16 Quantification of retinal transneuronal degeneration in human glaucoma: a novel multiphoton-DAPI approach. Invest Ophthalmol Vis Sci 2008 1.03
17 Autophagy in the retina: a potential role in age-related macular degeneration. Adv Exp Med Biol 2012 1.02
18 Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. PLoS One 2011 1.00
19 Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Invest Ophthalmol Vis Sci 2011 1.00
20 The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium. PLoS One 2012 0.99
21 γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. J Biol Chem 2011 0.98
22 A missense mutation in the murine Opa3 gene models human Costeff syndrome. Brain 2008 0.96
23 αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Mol Cancer Res 2011 0.95
24 Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow. Diabetes 2012 0.95
25 Advanced glycation end product (AGE) accumulation on Bruch's membrane: links to age-related RPE dysfunction. Invest Ophthalmol Vis Sci 2008 0.95
26 Using LC3 to monitor autophagy flux in the retinal pigment epithelium. Autophagy 2009 0.95
27 Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology. Proc Natl Acad Sci U S A 2013 0.94
28 Human RPE melanosomes protect from photosensitized and iron-mediated oxidation but become pro-oxidant in the presence of iron upon photodegradation. Invest Ophthalmol Vis Sci 2008 0.93
29 Retinal ganglion cell remodelling in experimental glaucoma. Adv Exp Med Biol 2006 0.93
30 Collagen ultrastructural changes during stromal wound healing in organ cultured bovine corneas. Exp Eye Res 2008 0.92
31 Adhesion of laser in situ keratomileusis-like flaps in the cornea: Effects of crosslinking, stromal fibroblasts, and cytokine treatment. J Cataract Refract Surg 2011 0.92
32 CNS inflammation and bone marrow neuropathy in type 1 diabetes. Am J Pathol 2013 0.92
33 Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3. PLoS One 2012 0.91
34 Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes. J Lipid Res 2014 0.89
35 Multiplex analysis of age-related protein and lipid modifications in human Bruch's membrane. FASEB J 2010 0.89
36 Poly(ADP-ribose) polymerase offers protection against oxidative and alkylation damage to the nuclear and mitochondrial genomes of the retinal pigment epithelium. Ophthalmic Res 2007 0.88
37 The phototoxicity of aged human retinal melanosomes. Photochem Photobiol 2007 0.88
38 Activation of the beta-catenin signaling pathway and its impact on RPE cell cycle. Invest Ophthalmol Vis Sci 2009 0.85
39 γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines. Invest Ophthalmol Vis Sci 2012 0.85
40 Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization. Am J Pathol 2013 0.85
41 In pursuit of new anti-angiogenic therapies for cancer treatment. Front Biosci (Landmark Ed) 2011 0.85
42 Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy 2015 0.85
43 Effects on collagen orientation in the cornea after trephine injury. Mol Vis 2009 0.84
44 Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes. PLoS One 2013 0.83
45 Cytotoxicity of all-trans-retinal increases upon photodegradation. Photochem Photobiol 2012 0.82
46 Nerve growth factor promotes endothelial progenitor cell-mediated angiogenic responses. Invest Ophthalmol Vis Sci 2012 0.82
47 Enhancing the function of CD34(+) cells by targeting plasminogen activator inhibitor-1. PLoS One 2013 0.81
48 Survivin expression is associated with lens epithelial cell proliferation and fiber cell differentiation. Mol Vis 2012 0.81
49 Epidermal growth factor: the driving force in initiation of RPE cell proliferation. Graefes Arch Clin Exp Ophthalmol 2011 0.81
50 Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development. Cancer Lett 2012 0.80
51 Erythropoietin: when liability becomes asset in neurovascular repair. J Clin Invest 2008 0.80
52 Non-dimensional analysis of retinal microaneurysms: critical threshold for treatment. Integr Biol (Camb) 2013 0.79
53 Concentration dependence of vitamin C in combinations with vitamin E and zeaxanthin on light-induced toxicity to retinal pigment epithelial cells. Photochem Photobiol 2012 0.78
54 Assessment of mitochondrial damage in retinal cells and tissues using quantitative polymerase chain reaction for mitochondrial DNA damage and extracellular flux assay for mitochondrial respiration activity. Methods Mol Biol 2013 0.76
55 Lipofuscin phototoxicity: reality or myth? J Cataract Refract Surg 2009 0.75