| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. | Proc Natl Acad Sci U S A | 2007 | 3.27 |
| 2 | Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. | Mol Cell | 2010 | 2.64 |
| 3 | Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays. | Clin Cancer Res | 2011 | 2.35 |
| 4 | Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924. | Cancer Cell | 2012 | 1.19 |
| 5 | Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905). | J Med Chem | 2011 | 0.80 |