John Bringas

Author PubWeight™ 41.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. Mol Ther 2006 2.41
2 Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents. J Neurosurg 2005 2.07
3 A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys. Mol Ther 2006 1.77
4 Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging. Brain Res Brain Res Protoc 2005 1.74
5 Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain. Hum Gene Ther 2006 1.72
6 Efficient gene therapy-based method for the delivery of therapeutics to primate cortex. Proc Natl Acad Sci U S A 2009 1.70
7 Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response. Hum Gene Ther 2009 1.55
8 Real-time MR imaging of adeno-associated viral vector delivery to the primate brain. Neuroimage 2008 1.53
9 Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys. Hum Gene Ther 2009 1.46
10 Biodistribution of adeno-associated virus type-2 in nonhuman primates after convection-enhanced delivery to brain. Mol Ther 2008 1.40
11 Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. J Neurosurg 2008 1.40
12 Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys. Hum Gene Ther 2009 1.36
13 Effects of the perivascular space on convection-enhanced delivery of liposomes in primate putamen. Exp Neurol 2005 1.32
14 Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC. Mol Ther 2010 1.31
15 Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates. Neuroimage 2009 1.24
16 Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys. Exp Neurol 2005 1.17
17 Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. J Neurosci 2010 1.14
18 Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors. Mol Ther 2010 1.09
19 Image-guided convection-enhanced delivery of GDNF protein into monkey putamen. Neuroimage 2010 1.02
20 Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum. Hum Gene Ther 2012 1.02
21 Basic fibroblast growth factor enhances transduction, distribution, and axonal transport of adeno-associated virus type 2 vector in rat brain. Hum Gene Ther 2004 1.00
22 Distribution of AAV2-hAADC-transduced cells after 3 years in Parkinsonian monkeys. Neuroreport 2006 1.00
23 Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics. J Neurosurg 2010 0.99
24 T2 imaging in monitoring of intraparenchymal real-time convection-enhanced delivery. Neurosurgery 2011 0.93
25 Design of an in-dwelling cannula for convection-enhanced delivery. J Neurosci Methods 2010 0.93
26 Comparison of two methods for the analysis of [18F]6-fluoro-L-m-tyrosine PET data. Neuroimage 2004 0.91
27 Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion. Exp Neurol 2011 0.89
28 Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain. Hum Gene Ther 2012 0.89
29 Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain. Magn Reson Med 2013 0.88
30 Merits of combination cortical, subcortical, and cerebellar injections for the treatment of Niemann-Pick disease type A. Mol Ther 2012 0.84
31 Invasive phenotype observed in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant sublines of 9L rat glioma cells: a tumor model mimicking a recurrent malignant glioma. J Neurosurg 2004 0.83
32 Anatomic compression caused by high-volume convection-enhanced delivery to the brain. Neurosurgery 2009 0.82
33 Evaluation of pressure-driven brain infusions in nonhuman primates by intra-operative 7 Tesla MRI. J Magn Reson Imaging 2012 0.77
34 The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys. Exp Neurol 2002 0.76