1
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PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis.
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Proc Natl Acad Sci U S A
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2009
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4.23
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2
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Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony.
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Mol Med
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2008
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2.93
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3
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De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial.
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Intensive Care Med
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2014
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2.77
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4
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Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock.
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Intensive Care Med
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2006
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2.56
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5
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Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25- lymphocytes.
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Crit Care Med
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2004
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2.51
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6
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Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients.
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Intensive Care Med
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2008
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2.34
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7
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Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis.
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Crit Care Med
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2003
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2.32
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8
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Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock.
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Intensive Care Med
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2010
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2.31
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9
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Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients.
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Crit Care Med
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2005
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2.07
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10
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Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients.
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Crit Care
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2011
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1.78
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11
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Assessment of pro-vasopressin and pro-adrenomedullin as predictors of 28-day mortality in septic shock patients.
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Intensive Care Med
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2009
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1.69
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12
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Decreased T-cell repertoire diversity in sepsis: a preliminary study.
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Crit Care Med
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2013
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1.62
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13
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Assessment of plasmatic immunoglobulin G, A and M levels in septic shock patients.
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Int Immunopharmacol
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2011
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1.60
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14
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Clinical and therapeutic features of nonpostoperative nosocomial intra-abdominal infections.
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Ann Surg
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2004
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1.57
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15
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Delayed increase of S100A9 messenger RNA predicts hospital-acquired infection after septic shock.
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Crit Care Med
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2011
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1.47
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16
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Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.
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Am J Respir Crit Care Med
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2015
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1.44
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17
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Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism.
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J Immunol
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2006
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1.41
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18
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IL-7 restores lymphocyte functions in septic patients.
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J Immunol
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2012
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1.39
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19
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Early assessment of leukocyte alterations at diagnosis of septic shock.
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Shock
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2010
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1.37
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20
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The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration.
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Immunol Lett
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2004
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1.37
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21
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Systemic transcriptional analysis in survivor and non-survivor septic shock patients: a preliminary study.
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Immunol Lett
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2006
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1.36
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22
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Clinical and microbiological profiles of community-acquired and nosocomial intra-abdominal infections: results of the French prospective, observational EBIIA study.
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J Antimicrob Chemother
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2009
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1.30
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23
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Analytical requirements for measuring monocytic human lymphocyte antigen DR by flow cytometry: application to the monitoring of patients with septic shock.
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Clin Chem
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2002
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1.20
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24
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Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock.
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Crit Care Med
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2005
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1.18
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25
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Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.
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Am J Respir Crit Care Med
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2012
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1.16
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26
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Decreased expression of the fractalkine receptor CX3CR1 on circulating monocytes as new feature of sepsis-induced immunosuppression.
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J Immunol
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2008
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1.09
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27
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Compliance with guidelines on antibiotic prophylaxis in total hip replacement surgery: results of a retrospective study of 416 patients in a teaching hospital.
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Infect Control Hosp Epidemiol
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2004
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1.02
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28
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Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
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Intensive Care Med
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2015
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0.98
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29
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Early- and late-onset ventilator-associated pneumonia acquired in the intensive care unit: comparison of risk factors.
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J Crit Care
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2007
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0.97
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30
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Development and validation of a questionnaire for quantitative assessment of perceived discomforts in critically ill patients.
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Intensive Care Med
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2010
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0.97
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31
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Clinical review: flow cytometry perspectives in the ICU - from diagnosis of infection to monitoring of injury-induced immune dysfunctions.
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Crit Care
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2011
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0.97
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32
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mRNA-based approach to monitor recombinant gamma-interferon restoration of LPS-induced endotoxin tolerance.
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Crit Care
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2011
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0.96
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33
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Inter-laboratory assessment of flow cytometric monocyte HLA-DR expression in clinical samples.
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Cytometry B Clin Cytom
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2012
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0.96
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34
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Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock.
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Crit Care
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2013
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0.94
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35
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Longitudinal study of cytokine and immune transcription factor mRNA expression in septic shock.
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Clin Immunol
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2005
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0.93
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36
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Prevention of ventilator-associated pneumonia in intensive care units: an international online survey.
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Antimicrob Resist Infect Control
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2013
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0.93
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37
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Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients.
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Crit Care
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2010
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0.92
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38
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Family participation in care to the critically ill: opinions of families and staff.
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Intensive Care Med
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2003
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0.92
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39
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Nosocomial infection after septic shock among intensive care unit patients.
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Infect Control Hosp Epidemiol
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2008
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0.91
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40
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Estimating attributable mortality due to nosocomial infections acquired in intensive care units.
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Infect Control Hosp Epidemiol
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2010
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0.89
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41
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Early-onset ventilator-associated pneumonia incidence in intensive care units: a surveillance-based study.
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BMC Infect Dis
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2011
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0.87
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42
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Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach.
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Intensive Care Med Exp
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2014
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0.85
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43
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Soluble human leukocyte antigen-G5 in septic shock: marked and persisting elevation as a predictor of survival.
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Crit Care Med
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2007
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0.85
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44
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The Th2 response as monitored by CRTH2 or CCR3 expression is severely decreased during septic shock.
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Clin Immunol
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2004
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0.84
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45
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Strategies of initiation and streamlining of antibiotic therapy in 41 French intensive care units.
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Crit Care
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2011
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0.84
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46
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Calcitonin gene related peptide and N-procalcitonin modulate CD11b upregulation in lipopolysaccharide activated monocytes and neutrophils.
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Intensive Care Med
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2003
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0.84
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47
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Elevated plasmatic level of soluble IL-7 receptor is associated with increased mortality in septic shock patients.
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Intensive Care Med
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2014
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0.82
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48
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Novel isoprenoyl nanoassembled prodrug for paclitaxel delivery.
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Bioconjug Chem
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2013
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0.81
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49
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Fast renal trapping of porcine luteinizing hormone (pLH) shown by 123I-scintigraphic imaging in rats explains its short circulatory half-life.
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Reprod Biol Endocrinol
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2003
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0.81
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50
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Proatrial natriuretic peptide is a better predictor of 28-day mortality in septic shock patients than proendothelin-1.
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Clin Chem Lab Med
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2010
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0.80
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51
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A dynamic view of mHLA-DR expression in management of severe septic patients.
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Crit Care
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2011
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0.80
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52
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Innovative therapeutic strategies for restoring lymphocyte functions in septic patients.
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Inflamm Allergy Drug Targets
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2008
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0.80
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53
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Persistent high level of circulating midregional-proadrenomedullin and increased risk of nosocomial infections after septic shock.
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J Trauma Acute Care Surg
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2012
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0.79
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54
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Reduction of urinary tract infections acquired in an intensive care unit during a 10-year surveillance program.
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Eur J Epidemiol
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2008
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0.79
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55
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Identification of biomarkers of response to IFNg during endotoxin tolerance: application to septic shock.
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PLoS One
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2013
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0.78
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56
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Increased MerTK expression in circulating innate immune cells of patients with septic shock.
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Intensive Care Med
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2013
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0.78
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57
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Assessment of a novel flow cytometry technique of one-step intracellular staining: example of FOXP3 in clinical samples.
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Cytometry B Clin Cytom
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2013
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0.76
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58
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Comparison of four skin preparation strategies to prevent catheter-related infection in intensive care unit (CLEAN trial): a study protocol for a randomized controlled trial.
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Trials
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2013
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0.75
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59
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Relevance of blood cultures in acute pyelonephritis in a single-center retrospective study.
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Intern Emerg Med
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2015
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0.75
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60
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Effect of standardized surveillance of intensive care unit-acquired infections on ventilator-associated pneumonia incidence.
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Infect Control Hosp Epidemiol
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2014
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0.75
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