Simon H S Pearce

Author PubWeight™ 63.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007 12.62
2 FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet 2007 5.93
3 Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice. J Clin Invest 2008 2.69
4 The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis. J Clin Endocrinol Metab 2008 2.35
5 Levothyroxine treatment of subclinical hypothyroidism, fatal and nonfatal cardiovascular events, and mortality. Arch Intern Med 2012 1.79
6 The incidence of ischemic heart disease and mortality in people with subclinical hypothyroidism: reanalysis of the Whickham Survey cohort. J Clin Endocrinol Metab 2010 1.58
7 Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility. J Clin Endocrinol Metab 2007 1.49
8 The genetics of autoimmune thyroid disease. J Clin Endocrinol Metab 2002 1.44
9 How should we treat patients with low serum thyrotropin concentrations? Clin Endocrinol (Oxf) 2009 1.43
10 Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study. Mech Ageing Dev 2011 1.36
11 Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome. J Clin Endocrinol Metab 2003 1.14
12 Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association. J Clin Endocrinol Metab 2007 1.13
13 Unrecognised severe vitamin D deficiency. BMJ 2008 1.12
14 Management of hypothyroidism in adults. BMJ 2008 1.11
15 Role of the CD40 locus in Graves' disease. Thyroid 2004 1.04
16 Treatment for primary hypothyroidism: current approaches and future possibilities. Drug Des Devel Ther 2011 1.02
17 Autoimmune Addison disease: pathophysiology and genetic complexity. Nat Rev Endocrinol 2012 1.00
18 Trends in thyroid hormone prescribing and consumption in the UK. BMC Public Health 2009 0.97
19 Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. J Clin Endocrinol Metab 2009 0.97
20 Diagnostic challenges due to phenocopies: lessons from Multiple Endocrine Neoplasia type1 (MEN1). Hum Mutat 2010 0.96
21 Left ventricular apical ballooning (takotsubo cardiomyopathy) in thyrotoxicosis. Thyroid 2007 0.94
22 Genetic association studies of the FOXP3 gene in Graves' disease and autoimmune Addison's disease in the United Kingdom population. J Mol Endocrinol 2006 0.94
23 Perrault syndrome: further evidence for genetic heterogeneity. J Neurol 2011 0.91
24 The effect of B cell depletion therapy on anti-TSH receptor antibodies and clinical outcome in glucocorticoid-refractory Graves' orbitopathy. Clin Endocrinol (Oxf) 2013 0.87
25 Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment. J Clin Endocrinol Metab 2013 0.87
26 Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people. J Clin Endocrinol Metab 2012 0.85
27 Anti-neutrophil cytoplasmic antibody (ANCA) associated small-vessel vasculitis in a patient with diabetic nephropathy and autoimmune polyendocrinopathy syndrome (APS) Type 2: a case report. Clin Nephrol 2013 0.85
28 Subclinical thyroid disorders: significance and clinical impact. J Clin Pathol 2010 0.85
29 Radioiodine treatment for benign thyroid disorders: results of a nationwide survey of UK endocrinologists. Clin Endocrinol (Oxf) 2007 0.84
30 Extracellular calcium-sensing receptor dysfunction is associated with two new phenotypes. Clin Endocrinol (Oxf) 2003 0.84
31 Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study. Eur J Hum Genet 2010 0.83
32 Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity. J Mol Med (Berl) 2009 0.81
33 No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease. Clin Endocrinol (Oxf) 2005 0.79
34 Prevention and treatment of vitamin D deficiency. Calcif Tissue Int 2012 0.78
35 Autoimmune Addison's disease. Presse Med 2012 0.78
36 Discordance for X-linked hypophosphataemic rickets in identical twin girls. Horm Res 2009 0.77
37 What is the evidence behind the evidence-base? The premature death of block-replace antithyroid drug regimens for Graves' disease. Eur J Endocrinol 2006 0.77
38 The role of a nonsynonymous CD226 (DNAX-accessory molecule-1) variant (Gly 307Ser) in isolated Addison's disease and autoimmune polyendocrinopathy type 2 pathogenesis. Clin Endocrinol (Oxf) 2011 0.77
39 Toward precise forecasting of autoimmune endocrinopathy. J Clin Endocrinol Metab 2004 0.77
40 The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease. Eur J Endocrinol 2012 0.76
41 Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells. Biochem Biophys Res Commun 2003 0.75
42 Study protocol for the randomised controlled trial: antiglucocorticoid augmentation of anti-Depressants in Depression (The ADD Study). BMC Psychiatry 2013 0.75
43 Sun and melanoma: Time to go to get your hat. BMJ 2008 0.75
44 Medical therapy of macroprolactinomas in males: I. Prevalence of hypopituitarism at diagnosis. II. Proportion of cases exhibiting recovery of pituitary function. Pituitary 2002 0.75
45 Saving lives of in-patients with adrenal insufficiency: implementation of an alert scheme within the Newcastle-upon-Tyne Hospitals e-Prescribing platform. Clin Endocrinol (Oxf) 2014 0.75
46 Do antithyroid drugs influence outcome after radioiodine therapy for hyperthyroidism? Nat Clin Pract Endocrinol Metab 2007 0.75
47 Primary hyperparathyroidism: just how 'primary' is it really? Ther Adv Endocrinol Metab 2010 0.75
48 Correction: Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus. PLoS One 2015 0.75
49 Subclinical hypothyroidism and cardiovascular disease-reply. Arch Intern Med 2012 0.75
50 How should I approach standard endocrine evaluation in patients with coeliac disease? Clin Endocrinol (Oxf) 2013 0.75
51 Current and emerging therapies for Addison's disease. Curr Opin Endocrinol Diabetes Obes 2014 0.75
52 Genetic progress towards the molecular basis of common autoimmunity. Discov Med 2006 0.75