| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells.
|
Cancer Res
|
2007
|
2.50
|
|
2
|
Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease.
|
Gastroenterology
|
2007
|
2.25
|
|
3
|
Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice.
|
Hepatology
|
2002
|
2.10
|
|
4
|
Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice.
|
Hepatology
|
2006
|
2.08
|
|
5
|
Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway.
|
Hepatology
|
2010
|
1.86
|
|
6
|
Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.
|
Hepatology
|
2005
|
1.81
|
|
7
|
An assessment of statin safety by hepatologists.
|
Am J Cardiol
|
2006
|
1.78
|
|
8
|
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor.
|
Cancer Res
|
2008
|
1.67
|
|
9
|
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation.
|
FASEB J
|
2004
|
1.61
|
|
10
|
The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology.
|
Am J Pathol
|
2005
|
1.49
|
|
11
|
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3.
|
J Biol Chem
|
2007
|
1.48
|
|
12
|
Shanthi V. Sitaraman, MD, PhD: physician, scientist, educator, and humanitarian.
|
Gastroenterology
|
2011
|
1.39
|
|
13
|
Racial differences in liver inflammation and fibrosis related to chronic hepatitis C.
|
Clin Gastroenterol Hepatol
|
2004
|
1.32
|
|
14
|
GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy.
|
PLoS One
|
2011
|
1.26
|
|
15
|
Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis.
|
Hepatology
|
2010
|
1.23
|
|
16
|
Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma.
|
Gastroenterology
|
2010
|
1.20
|
|
17
|
Epstein-Barr virus induced hepatitis: An important cause of cholestasis.
|
Hepatol Res
|
2005
|
1.20
|
|
18
|
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells.
|
J Cell Biochem
|
2003
|
1.19
|
|
19
|
Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet.
|
Am J Physiol Gastrointest Liver Physiol
|
2011
|
1.19
|
|
20
|
Leptin increases tissue inhibitor of metalloproteinase I (TIMP-1) gene expression by a specificity protein 1/signal transducer and activator of transcription 3 mechanism.
|
Mol Endocrinol
|
2006
|
1.09
|
|
21
|
Adiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS-3).
|
J Cell Biochem
|
2010
|
1.07
|
|
22
|
Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver.
|
Hepatology
|
2004
|
1.06
|
|
23
|
Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis.
|
Biochem J
|
2011
|
0.99
|
|
24
|
Antagonistic interaction between Wnt and Notch activity modulates the regenerative capacity of a zebrafish fibrotic liver model.
|
Hepatology
|
2014
|
0.90
|
|
25
|
The prevalence and clinical correlates of nonalcoholic fatty liver disease (NAFLD) in African Americans: the multiethnic study of atherosclerosis (MESA).
|
Dig Dis Sci
|
2013
|
0.88
|
|
26
|
Terbinafine hepatotoxicity resulting in chronic biliary ductopenia and portal fibrosis.
|
Am J Med
|
2002
|
0.87
|
|
27
|
The role of gastrointestinal hormones in hepatic lipid metabolism.
|
Semin Liver Dis
|
2013
|
0.83
|
|
28
|
Treatment of fibrosis in nonalcoholic fatty liver disease.
|
Curr Gastroenterol Rep
|
2007
|
0.78
|
|
29
|
Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity.
|
Am J Physiol Gastrointest Liver Physiol
|
2014
|
0.78
|
|
30
|
Adiponectin and alcoholic fatty liver: Is it, after all, about what you eat?
|
Hepatology
|
2005
|
0.77
|
|
31
|
Chlorzoxazone as a cause of acute liver failure requiring liver transplantation.
|
Dig Dis Sci
|
2007
|
0.77
|
|
32
|
Connecting the dots from fatty acids to nonalcoholic steatohepatitis: epigenetics in the spotlight.
|
Hepatology
|
2013
|
0.75
|
|
33
|
Increased liver enzyme levels and HNF-1beta gene mutation.
|
Clin Gastroenterol Hepatol
|
2008
|
0.75
|
|
34
|
The Diabetes Prevention Program and the metabolic syndrome.
|
Ann Intern Med
|
2005
|
0.75
|
|
35
|
Recent changes in relationships between medical school physicians and industry.
|
Gastroenterology
|
2010
|
0.75
|
|
36
|
Hepatorenal syndrome. Definition, pathophysiology, and intervention.
|
Crit Care Clin
|
2002
|
0.75
|