Published in Blood on October 31, 2011
IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients. Blood (2012) 1.65
International Consensus Document (ICON): Common Variable Immunodeficiency Disorders. J Allergy Clin Immunol Pract (2015) 1.11
Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans. J Autoimmun (2013) 1.07
Common variable immunodeficiency and idiopathic primary hypogammaglobulinemia: two different conditions within the same disease spectrum. Haematologica (2013) 0.88
Common variable immune deficiency in children--clinical characteristics varies depending on defect in peripheral B cell maturation. J Clin Immunol (2013) 0.79
Strategies for B-cell receptor repertoire analysis in primary immunodeficiencies: from severe combined immunodeficiency to common variable immunodeficiency. Front Immunol (2015) 0.79
Levels of somatic hypermutations in B cell receptors increase during childhood. Clin Exp Immunol (2014) 0.79
Reduced CD19 expression and decreased memory B cell numbers in transient hypogammaglobulinemia of infancy. Clin Exp Med (2012) 0.77
IgH sequences in common variable immune deficiency reveal altered B cell development and selection. Sci Transl Med (2015) 0.77
Long-term follow-up on affinity maturation and memory B-cell generation in patients with common variable immunodeficiency. J Clin Immunol (2013) 0.76
Immune Dysfunction in Children with CHARGE Syndrome: A Cross-Sectional Study. PLoS One (2015) 0.75
Impaired Antigen-Specific Immune Response to Vaccines in Children with Antibody Production Defects. Clin Vaccine Immunol (2015) 0.75
Phenotypic and Functional Comparison of Class Switch Recombination Deficiencies with a Subgroup of Common Variable Immunodeficiencies. J Clin Immunol (2016) 0.75
The 11q Terminal Deletion Disorder Jacobsen Syndrome is a Syndromic Primary Immunodeficiency. J Clin Immunol (2015) 0.75
Trying to Understand NK Cell Function in vivo Points towards a Severity Score for CVID Patients. EBioMedicine (2016) 0.75
Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia. Sci Rep (2017) 0.75
The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives. Haematologica (2016) 0.75
Somatic Hypermutation Defects in Common Variable Immune Deficiency. Curr Allergy Asthma Rep (2017) 0.75
Analysis of clinical and immunologic phenotype in a large cohort of children and adults with cartilage-hair hypoplasia. J Allergy Clin Immunol (2017) 0.75
A previously undescribed coronavirus associated with respiratory disease in humans. Proc Natl Acad Sci U S A (2004) 5.76
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med (2009) 4.97
Recent trends of cancer in Europe: a combined approach of incidence, survival and mortality for 17 cancer sites since the 1990s. Eur J Cancer (2008) 4.41
New common variants affecting susceptibility to basal cell carcinoma. Nat Genet (2009) 4.15
The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood (2007) 4.14
The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell (2008) 3.92
The natural course of infantile Pompe's disease: 20 original cases compared with 133 cases from the literature. Pediatrics (2003) 3.24
Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands. Gastroenterology (2008) 3.18
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. J Exp Med (2011) 2.96
Role of truncating mutations in MME gene in fetomaternal alloimmunisation and antenatal glomerulopathies. Lancet (2004) 2.82
An antibody-deficiency syndrome due to mutations in the CD19 gene. N Engl J Med (2006) 2.77
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling. J Exp Med (2005) 2.44
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood (2008) 2.37
Long-term intravenous treatment of Pompe disease with recombinant human alpha-glucosidase from milk. Pediatrics (2004) 2.33
Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis. Pediatr Pulmonol (2011) 2.32
Open lung ventilation improves functional residual capacity after extubation in cardiac surgery. Crit Care Med (2005) 2.28
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood (2011) 2.18
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell (2011) 2.18
Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways. Blood (2011) 2.15
Therapeutic drug monitoring of voriconazole. Ther Drug Monit (2008) 2.09
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence. Cancer (2005) 2.08
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion. J Exp Med (2007) 2.05
Intrathecal vincristine: 3 fatal cases and a review of the literature. J Pediatr Hematol Oncol (2009) 2.04
Carriage of Mycoplasma pneumoniae in the upper respiratory tract of symptomatic and asymptomatic children: an observational study. PLoS Med (2013) 1.95
Superior outcome of women with stage I/II cutaneous melanoma: pooled analysis of four European Organisation for Research and Treatment of Cancer phase III trials. J Clin Oncol (2012) 1.93
Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction. J Infect Dis (2003) 1.91
Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells. Proc Natl Acad Sci U S A (2009) 1.91
Nontuberculous mycobacterial infection in children: a 2-year prospective surveillance study in the Netherlands. Clin Infect Dis (2004) 1.85
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining. J Clin Invest (2008) 1.82
Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth. Pediatrics (2002) 1.82
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J Clin Invest (2010) 1.79
Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition. J Clin Oncol (2011) 1.71
Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency. Blood (2005) 1.63
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression. J Immunol (2005) 1.61
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation. J Clin Invest (2005) 1.59
Chromatin architecture and the generation of antigen receptor diversity. Cell (2009) 1.59
Intrinsic abnormalities of lymphocyte counts in children with down syndrome. J Pediatr (2005) 1.59
Enzyme replacement therapy in late-onset Pompe's disease: a three-year follow-up. Ann Neurol (2004) 1.58
Multidrug resistance in Aspergillus fumigatus. N Engl J Med (2002) 1.54
Is prevention of cancer by sun exposure more than just the effect of vitamin D? A systematic review of epidemiological studies. Eur J Cancer (2012) 1.54
Idiopathic CD4+ T lymphopenia without autoimmunity or granulomatous disease in the slipstream of RAG mutations. Blood (2011) 1.53
Macrolide resistance determination and molecular typing of Mycoplasma pneumoniae by pyrosequencing. J Microbiol Methods (2010) 1.53
The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene. Haematologica (2006) 1.52
Anti-TNF treatment blocks the induction of T cell-dependent humoral responses. Ann Rheum Dis (2012) 1.51
Progress in standard of care therapy and modest survival benefits in the treatment of non-small cell lung cancer patients in the Netherlands in the last 20 years. J Thorac Oncol (2012) 1.51
Sequence variations in RepMP2/3 and RepMP4 elements reveal intragenomic homologous DNA recombination events in Mycoplasma pneumoniae. Microbiology (2009) 1.48
An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity. DNA Repair (Amst) (2010) 1.46
[Contribution of lifestyle factors to cancer: secondary analysis of Dutch data over 2010 and a projection for 2020]. Ned Tijdschr Geneeskd (2014) 1.46
Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL. Blood (2002) 1.45
Nonsolar occupational risk factors for cutaneous melanoma. Int J Dermatol (2008) 1.44
Gender differences in melanoma survival: female patients have a decreased risk of metastasis. J Invest Dermatol (2010) 1.42
Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J Immunol (2004) 1.41
X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease. Blood (2010) 1.40
A randomized trial of cryo stripping versus conventional stripping of the great saphenous vein. J Vasc Surg (2008) 1.40
High-dose intravenous immunoglobulin does not reduce the numbers of circulating CD14(+)CD16(++) monocytes in patients with inflammatory disorders. Clin Immunol (2012) 1.39
[Basal cell carcinoma: often more than one]. Ned Tijdschr Geneeskd (2011) 1.39
Decreased expression of serum and microvascular vascular endothelial growth factor receptor-2 in meningococcal sepsis*. Pediatr Crit Care Med (2013) 1.38
Trichodysplasia spinulosa is characterized by active polyomavirus infection. J Clin Virol (2011) 1.36
1,3-beta-D-glucan in patients receiving intravenous amoxicillin-clavulanic acid. N Engl J Med (2006) 1.35
T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus? Arthritis Res Ther (2014) 1.34
Aspergillus species intrinsically resistant to antifungal agents. Med Mycol (2010) 1.33
After-hours colorectal surgery: a risk factor for anastomotic leakage. Int J Colorectal Dis (2009) 1.29
Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential. Blood (2005) 1.29
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules. Proc Natl Acad Sci U S A (2006) 1.24
Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2. Am J Hum Genet (2011) 1.24
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow. Blood (2002) 1.23
Clinical impact of RT-PCR for pediatric acute respiratory infections: a controlled clinical trial. Pediatrics (2011) 1.23
The nature of circulating CD27+CD43+ B cells. J Exp Med (2011) 1.22
Aspergillus fumigatus conidial melanin modulates host cytokine response. Immunobiology (2009) 1.21
Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection. Clin Cancer Res (2005) 1.21
Mutations in TTC37 cause trichohepatoenteric syndrome (phenotypic diarrhea of infancy). Gastroenterology (2010) 1.20
Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study. Hum Mutat (2012) 1.19
Gene therapy: is IL2RG oncogenic in T-cell development? Nature (2006) 1.18
BIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics. J Mol Diagn (2005) 1.17
Generation of flow cytometry data files with a potentially infinite number of dimensions. Cytometry A (2008) 1.16
Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL. Blood (2007) 1.15
Sunlight, vitamin D and the prevention of cancer: a systematic review of epidemiological studies. Eur J Cancer Prev (2009) 1.15
Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells. Am J Physiol Endocrinol Metab (2003) 1.15
Predominance of rhinovirus in the nose of symptomatic and asymptomatic infants. Pediatr Allergy Immunol (2003) 1.14