Published in Eur Cytokine Netw on September 01, 2011
Epithelial expression of interleukin-37b in inflammatory bowel disease. Clin Exp Immunol (2013) 1.28
Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A (2014) 1.14
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease. Front Immunol (2013) 1.11
IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity. J Transl Med (2014) 1.10
Elevated plasma IL-37, IL-18, and IL-18BP concentrations in patients with acute coronary syndrome. Mediators Inflamm (2014) 1.10
IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. PLoS Pathog (2014) 1.05
Interleukin-18 mediates interleukin-1-induced cardiac dysfunction. Am J Physiol Heart Circ Physiol (2014) 1.00
TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity. Front Immunol (2012) 0.99
Different Members of the IL-1 Family Come Out in Different Ways: DAMPs vs. Cytokines? Front Immunol (2013) 0.98
Cytokines in psoriasis. Cytokine (2015) 0.98
Elevated levels of cerebrospinal fluid and plasma interleukin-37 in patients with Guillain-Barré syndrome. Mediators Inflamm (2013) 0.96
Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure. Mol Med (2014) 0.95
Suppression of innate inflammation and immunity by interleukin-37. Eur J Immunol (2016) 0.94
Plasma levels of IL-37 and correlation with TNF-α, IL-17A, and disease activity during DMARD treatment of rheumatoid arthritis. PLoS One (2014) 0.94
B cells responses and cytokine production are regulated by their immune microenvironment. Cytokine (2015) 0.93
Serum interleukin-37 concentrations and HBeAg seroconversion in chronic HBV patients during telbivudine treatment. J Interferon Cytokine Res (2013) 0.92
Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV. Scientifica (Cairo) (2014) 0.92
MyD88 and its divergent toll in carcinogenesis. Trends Immunol (2013) 0.88
Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD. Thorax (2014) 0.88
IL-27 Regulates IL-18 binding protein in skin resident cells. PLoS One (2012) 0.87
IL-37b gene transfer enhances the therapeutic efficacy of mesenchumal stromal cells in DSS-induced colitis mice. Acta Pharmacol Sin (2015) 0.87
The possible role of the novel cytokines il-35 and il-37 in inflammatory bowel disease. Mediators Inflamm (2014) 0.86
IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance. Cytokine (2015) 0.85
Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis. J Neuroinflammation (2014) 0.85
Differential expression of interleukin-1/Toll-like receptor signaling regulators in microscopic and ulcerative colitis. World J Gastroenterol (2014) 0.84
Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc Natl Acad Sci U S A (2017) 0.84
The IL-1 cytokine family and its role in inflammation and fibrosis in the lung. Semin Immunopathol (2016) 0.83
Biomarkers of postoperative delirium and cognitive dysfunction. Front Aging Neurosci (2015) 0.82
Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer. J Exp Clin Cancer Res (2016) 0.81
Analysis of protein isoforms: can we do it better? Proteomics (2012) 0.80
Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37. Front Microbiol (2015) 0.80
Expression of IL-37 contributes to the immunosuppressive property of human CD4(+)CD25(+) regulatory T cells. Sci Rep (2015) 0.80
Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia. Clin Exp Immunol (2015) 0.80
Immunobiology of IL-37: mechanism of action and clinical perspectives. Expert Rev Clin Immunol (2014) 0.79
Immunology of hepatic diseases during pregnancy. Semin Immunopathol (2016) 0.78
Interleukin-37 is increased in ankylosing spondylitis patients and associated with disease activity. J Transl Med (2015) 0.78
Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells. Int J Clin Exp Med (2015) 0.77
Cytokine regulation of immune tolerance. Burns Trauma (2014) 0.77
Association of interleukin 1 family with systemic sclerosis. Inflammation (2014) 0.76
Expression and Regulation of Interleukin-37 in Pathogenesis of Nasal Polyps. Indian J Otolaryngol Head Neck Surg (2014) 0.76
Transfer of the IL-37b gene elicits anti-tumor responses in mice bearing 4T1 breast cancer. Acta Pharmacol Sin (2015) 0.76
Identification of a truncated splice variant of IL-18 receptor alpha in the human and rat, with evidence of wider evolutionary conservation. PeerJ (2014) 0.76
Anti-inflammatory effect of IL-37b in children with allergic rhinitis. Mediators Inflamm (2014) 0.76
Interleukin-37 gene variants segregated anciently coexist during hominid evolution. Eur J Hum Genet (2015) 0.76
IL-37 inhibits the production of pro-inflammatory cytokines in MSU crystal-induced inflammatory response. Clin Rheumatol (2015) 0.76
Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma. Sci Rep (2016) 0.76
The Low Expression of IL-37 Involved in Multiple Myeloma - Associated Angiogenesis. Med Sci Monit (2016) 0.75
Elevated plasma interleukin-37 playing an important role in acute coronary syndrome through suppression of ROCK activation. Oncotarget (2017) 0.75
Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice. Sci Rep (2015) 0.75
Intracellular IL-37b interacts with Smad3 to suppress multiple signaling pathways and the metastatic phenotype of tumor cells. Oncogene (2017) 0.75
Interleukin-37 Enhances the Suppressive Activity of Naturally Occurring CD4(+)CD25(+) Regulatory T Cells. Sci Rep (2016) 0.75
The chicken IL-1 family: evolution in the context of the studied vertebrate lineage. Immunogenetics (2014) 0.75
Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus. Sci Rep (2016) 0.75
Genomic Variant in IL-37 Confers A Significant Risk of Coronary Artery Disease. Sci Rep (2017) 0.75
Outcomes of Interferon/Ribavirin Therapy in Patients with HCV Defined by Expression of Plasma Soluble Human Leukocyte Antigen-G but Not IL-37. Med Sci Monit (2016) 0.75
Development and characterization of monoclonal antibody against human IL-37b. Cytotechnology (2017) 0.75
IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells. Mol Med (2017) 0.75
IL-37 restrains autoimmune diseases. Oncotarget (2015) 0.75
Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma. Inflammation (2016) 0.75
The emerging role of interleukin-37 in cardiovascular diseases. Immun Inflamm Dis (2017) 0.75
The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice. Int J Mol Sci (2017) 0.75
Plasma IL-37 Elevated in Patients with Chronic Heart Failure and Predicted Major Adverse Cardiac Events: A 1-Year Follow-Up Study. Dis Markers (2017) 0.75
Elevated IL-37 levels in the plasma of patients with severe coronary artery calcification. J Geriatr Cardiol (2017) 0.75
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood (2008) 4.63
Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation (2003) 4.09
IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A (2003) 3.80
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med (2003) 3.54
Interleukin-32: a cytokine and inducer of TNFalpha. Immunity (2005) 3.39
IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol (2010) 3.27
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci U S A (2009) 3.07
The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A (2002) 2.91
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc Natl Acad Sci U S A (2014) 2.86
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat Med (2006) 2.86
Inflammasome activation and IL-1β and IL-18 processing during infection. Trends Immunol (2011) 2.75
IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A (2006) 2.67
CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J Immunol (2005) 2.63
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res (2007) 2.62
The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proc Natl Acad Sci U S A (2004) 2.61
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A (2005) 2.46
Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect. Proc Natl Acad Sci U S A (2004) 2.41
Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease. Proc Natl Acad Sci U S A (2010) 2.38
Time evolution of the nanoparticle protein corona. ACS Nano (2010) 2.30
IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol (2011) 2.25
Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. J Clin Invest (2008) 2.23
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum (2009) 2.23
Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthritis Rheum (2005) 2.13
The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo. Mol Med (2006) 2.11
Histone hyperacetylation is associated with amelioration of experimental colitis in mice. J Immunol (2006) 2.09
The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J Immunol (2008) 2.08
Interleukin 37 expression protects mice from colitis. Proc Natl Acad Sci U S A (2011) 2.06
Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci U S A (2010) 2.04
Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism. PLoS Med (2006) 2.04
Self-harm or attempted suicide? Do suicide notes help us decide the level of intent in those who survive? Accid Emerg Nurs (2007) 2.03
Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J Hepatol (2011) 2.02
Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia. Ann Thorac Surg (2008) 1.91
Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. J Pharmacol Exp Ther (2007) 1.88
Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice. Gut (2013) 1.84
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol (2010) 1.82
IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol (2010) 1.79
IL-1 family nomenclature. Nat Immunol (2010) 1.79
A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci U S A (2002) 1.78
Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway. Cancer Res (2009) 1.78
Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial. Crit Care Med (2016) 1.76
IL-18 in autoimmunity: review. Eur Cytokine Netw (2006) 1.76
Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria. Infect Immun (2003) 1.75
Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality. Am J Respir Crit Care Med (2008) 1.73
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem (2009) 1.67
Exercise training and heart failure: a systematic review of current evidence. Br J Gen Pract (2002) 1.67
The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis. J Immunol (2009) 1.65
Interleukin-1beta and the autoinflammatory diseases. N Engl J Med (2009) 1.63
Type 2 diabetes mellitus in nursing home patients: effects on bone turnover, bone mass, and fracture risk. J Clin Endocrinol Metab (2006) 1.63
Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proc Natl Acad Sci U S A (2005) 1.61
Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis. Am J Physiol Cell Physiol (2007) 1.58
Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney Int (2004) 1.57
The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest (2010) 1.57
Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem J (2004) 1.57
Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol (2002) 1.56
Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood (2005) 1.53
alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A (2008) 1.53
Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum (2011) 1.52
Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study. J Am Geriatr Soc (2003) 1.51
Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood (2006) 1.48
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 1.47
Endogenous IL-32 controls cytokine and HIV-1 production. J Immunol (2008) 1.47
Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care (2012) 1.46
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911. J Immunol (2007) 1.45
Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. J Immunol (2009) 1.45
IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites. Eur J Immunol (2006) 1.43
Comment on "Power of rare diseases: found in translation". Sci Transl Med (2014) 1.43
Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels. J Infect Dis (2007) 1.42
Identification of the most active interleukin-32 isoform. Immunology (2008) 1.41
Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1α. Proc Natl Acad Sci U S A (2011) 1.41
Differences in signaling pathways by IL-1beta and IL-18. Proc Natl Acad Sci U S A (2004) 1.40
Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci U S A (2008) 1.38
Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol (2009) 1.37
Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. J Infect Dis (2009) 1.37
Interleukin-32 induces the differentiation of monocytes into macrophage-like cells. Proc Natl Acad Sci U S A (2008) 1.37
Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. Am J Respir Cell Mol Biol (2004) 1.36
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. J Leukoc Biol (2006) 1.34
Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis (2006) 1.34
Proteinase 3 is an IL-32 binding protein. Proc Natl Acad Sci U S A (2006) 1.32
IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 1.31
Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir. Mol Med (2011) 1.30
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Mol Med (2012) 1.27
In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis. ScientificWorldJournal (2011) 1.27
Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice. Am J Physiol Renal Physiol (2005) 1.26
Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behcet's disease: an open-label pilot study. Ann Rheum Dis (2011) 1.26
Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. J Mol Cell Cardiol (2011) 1.23
Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. FASEB J (2009) 1.23
The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. J Acquir Immune Defic Syndr (2010) 1.22
Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Mol Med (2011) 1.21
Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. Eur J Heart Fail (2010) 1.19