Karl Werdan

Author PubWeight™ 142.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 2012 9.22
2 Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial. Lancet 2012 6.42
3 Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet 2013 4.39
4 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011 3.68
5 Rehabilitation in Patients With Coronary Heart Disease: Participation and Its Effect on Prognosis. Dtsch Arztebl Int 2015 2.69
6 Right ventricular function in myocardial infarction complicated by cardiogenic shock: Improvement with levosimendan. Crit Care Med 2009 2.16
7 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009 2.10
8 Autonomic dysfunction predicts mortality in patients with multiple organ dysfunction syndrome of different age groups. Crit Care Med 2005 1.99
9 Intravascular embolization of venous catheter--causes, clinical signs, and management: a systematic review. JPEN J Parenter Enteral Nutr 2009 1.94
10 Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes. J Am Coll Cardiol 2013 1.89
11 Mirror, mirror on the wall, which is the fairest meta-analysis of all? Crit Care Med 2007 1.86
12 Intra-aortic balloon counterpulsation in patients with acute myocardial infarction complicated by cardiogenic shock: the prospective, randomized IABP SHOCK Trial for attenuation of multiorgan dysfunction syndrome. Crit Care Med 2010 1.84
13 Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. Am J Respir Crit Care Med 2004 1.72
14 Autonomic dysfunction predicts both 1- and 2-month mortality in middle-aged patients with multiple organ dysfunction syndrome. Crit Care Med 2008 1.66
15 Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial. Am Heart J 2012 1.65
16 Surgical trauma affects the proinflammatory status after cardiac surgery to a higher degree than cardiopulmonary bypass. J Thorac Cardiovasc Surg 2005 1.53
17 Transcoronary pacing in a porcine model--impact of guidewire insulation. J Invasive Cardiol 2011 1.42
18 Disseminated intravascular coagulation: a matter for immune globulins in sepsis? Crit Care Med 2006 1.41
19 Septic cardiomyopathy - A not yet discovered cardiomyopathy? Exp Clin Cardiol 2006 1.36
20 Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study. BMC Cardiovasc Disord 2005 1.33
21 Communication of end-of-life decisions in European intensive care units. Intensive Care Med 2005 1.28
22 Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction. Intensive Care Med 2003 1.25
23 Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ Cardiovasc Genet 2010 1.23
24 Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006. Eur J Epidemiol 2009 1.22
25 Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease. Nutr Metab (Lond) 2006 1.20
26 Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery? Dtsch Arztebl Int 2009 1.18
27 Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome. Intensive Care Med 2006 1.15
28 Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms. Innate Immun 2008 1.13
29 Cellular cardiomyoplasty: improvement of left ventricular function correlates with the release of cardioactive cytokines. Stem Cells 2006 1.13
30 Endotoxin impairs the human pacemaker current If. Shock 2007 1.10
31 Hemodynamic effects of intra-aortic balloon counterpulsation in patients with acute myocardial infarction complicated by cardiogenic shock: the prospective, randomized IABP shock trial. Shock 2012 1.04
32 Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy. Shock 2008 1.03
33 Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor. Proteomics 2007 1.01
34 Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use. Intensive Care Med 2002 0.99
35 Divergent siblings: E2F2 and E2F4 but not E2F1 and E2F3 induce DNA synthesis in cardiomyocytes without activation of apoptosis. Circ Res 2005 0.99
36 Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006. BMC Public Health 2011 0.98
37 Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study. PLoS One 2013 0.97
38 Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I (f) (funny channel current) inhibitor ivabradine : MODI (f)Y trial. Clin Res Cardiol 2011 0.96
39 Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock. Cochrane Database Syst Rev 2015 0.95
40 Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock. Cochrane Database Syst Rev 2011 0.94
41 The importance of genetic variants in TNFα for periodontal disease in a cohort of coronary patients. J Clin Periodontol 2012 0.94
42 Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys. Eur J Cardiovasc Prev Rehabil 2011 0.94
43 Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits. Biosci Rep 2002 0.94
44 Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6. Mol Med 2007 0.93
45 Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices. Europace 2007 0.93
46 Chemo- and ergoreflexes in health, disease and ageing. Int J Cardiol 2005 0.92
47 Intraaortic balloon support for cardiogenic shock. N Engl J Med 2013 0.91
48 Association of occupation with prevalent hypertension in an elderly East German population: an exploratory cross-sectional analysis. Int Arch Occup Environ Health 2010 0.90
49 Decreased beating rate variability of spontaneously contracting cardiomyocytes after co-incubation with endotoxin. J Endotoxin Res 2007 0.90
50 Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains. J Physiol 2013 0.90
51 Inhibition of p53 after acute myocardial infarction: reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture. J Mol Cell Cardiol 2010 0.90
52 Predictors of 30-day mortality in patients with refractory cardiogenic shock following acute myocardial infarction despite a patent infarct artery. Am Heart J 2009 0.89
53 Embolic events caused by aortic thrombi: an underestimated entity? J Thromb Thrombolysis 2013 0.89
54 Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. Hum Mol Genet 2012 0.88
55 Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production. Am J Physiol Heart Circ Physiol 2009 0.88
56 E2F2 expression induces proliferation of terminally differentiated cardiomyocytes in vivo. Cardiovasc Res 2008 0.88
57 Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study. Clin Res Cardiol 2011 0.88
58 PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: the AtheroGene study. J Lipid Res 2008 0.87
59 Apoptosis-modulating interaction of the neuregulin/erbB pathway with anthracyclines in regulating Bcl-xS and Bcl-xL in cardiomyocytes. J Mol Cell Cardiol 2005 0.87
60 Gender differences in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial. Clin Res Cardiol 2014 0.86
61 Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis. J Cell Mol Med 2011 0.86
62 The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis--novel genomic variants and functional consequences. Hum Mutat 2002 0.86
63 Relation between the tumor necrosis factor-alpha (TNF-alpha) gene and protein expression, and clinical, biochemical, and genetic markers: age, body mass index and uric acid are independent predictors for an elevated TNF-alpha plasma level in a complex risk model. Eur Cytokine Netw 2004 0.86
64 Interleukin-6, -7, -8 and -10 predict outcome in acute myocardial infarction complicated by cardiogenic shock. Clin Res Cardiol 2012 0.85
65 High serum thyrotropin levels are associated with current but not with incident hypertension. Thyroid 2013 0.85
66 Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures. J Cell Mol Med 2011 0.85
67 Is external defibrillation an electric threat for bystanders? Resuscitation 2009 0.85
68 In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves. Thromb Res 2010 0.85
69 Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome. Cochrane Database Syst Rev 2014 0.84
70 Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition. J Cardiovasc Pharmacol 2008 0.84
71 Anticoagulant and/or antiplatelet treatment in patients with atrial fibrillation after percutaneous coronary intervention. A single-center experience. Med Klin (Munich) 2008 0.83
72 Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury. Biochim Biophys Acta 2006 0.83
73 Phospholipid transfer protein in hemodialysis patients. Am J Nephrol 2007 0.82
74 Growth-differentiation factor 15 and osteoprotegerin in acute myocardial infarction complicated by cardiogenic shock: a biomarker substudy of the IABP-SHOCK II-trial. Eur J Heart Fail 2014 0.81
75 Neutrophils process interleukin-1beta and interleukin-18 precursors in a caspase-1-like fashion--processing is inhibited by human vascular smooth muscle cells. Eur Cytokine Netw 2006 0.81
76 Prognostic impact of autonomic information flow in multiple organ dysfunction syndrome patients. Int J Cardiol 2005 0.81
77 Proteome analysis of myocardial tissue following ischemia and reperfusion--effects of complement inhibition. Biochim Biophys Acta 2006 0.81
78 Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis. BMC Res Notes 2012 0.81
79 Endogenous ADP-ribosylation of elongation factor-2 by interleukin-1β. Mol Cell Biochem 2010 0.81
80 Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats. Circulation 2007 0.81
81 Optimal maximum tracking rate of dual-chamber pacemakers required by children and young adults for a maximal cardiorespiratory performance. Pacing Clin Electrophysiol 2005 0.81
82 Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosis. Clin Res Cardiol 2013 0.80
83 Comparison of outcome in 1809 patients treated with drug-eluting stents or bare-metal stents in a real-world setting. Vasc Health Risk Manag 2011 0.80
84 Role of LDL receptor-related protein (LRP) in coronary atherosclerosis. Int J Cardiol 2003 0.80
85 The direct thrombin inhibitor argatroban effectively prevents cardiac catheter thrombosis in vitro. Thromb Haemost 2010 0.80
86 Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice. Shock 2013 0.80
87 Differential reduction of HCN channel activity by various types of lipopolysaccharide. J Mol Cell Cardiol 2011 0.80
88 Comparison of unfractionated heparin, low-molecular-weight heparin, low-dose and high-dose rivaroxaban in preventing thrombus formation on mechanical heart valves: results of an in vitro study. J Thromb Thrombolysis 2011 0.80
89 The ageing heart: influence of cellular and tissue ageing on total content and distribution of the variants of elongation factor-2. Mech Ageing Dev 2002 0.80
90 Endogenous IgG hypogammaglobulinaemia in critically ill adults with sepsis: systematic review and meta-analysis. Intensive Care Med 2015 0.80
91 Prevalence and Incidence of Hypertension in the General Adult Population: Results of the CARLA-Cohort Study. Medicine (Baltimore) 2015 0.80
92 Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock. Crit Care Med 2007 0.80
93 The impact of impaired renal function on mortality in patients with acutely decompensated chronic heart failure. Eur J Heart Fail 2010 0.79
94 Intra-aortic balloon counterpulsation in the treatment of infarction-related cardiogenic shock--review of the current evidence. Artif Organs 2012 0.79
95 Genetic impact of TNF-beta on risk factors for coronary atherosclerosis. Eur Cytokine Netw 2006 0.79
96 Staphylococcus aureus α-toxin triggers the synthesis of B-cell lymphoma 3 by human platelets. Toxins (Basel) 2011 0.79
97 Temporary trans-coronary pacing by coated guidewires: a safe and reliable method during percutaneous coronary intervention. Clin Res Cardiol 2006 0.78
98 The human FGF2 level is influenced by genetic predisposition. Int J Cardiol 2005 0.78
99 The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist. Auton Autacoid Pharmacol 2002 0.78
100 Early and sustained haemodynamic improvement with levosimendan compared to intraaortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction. Acute Card Care 2008 0.78
101 Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis. Cell Cycle 2006 0.78
102 Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha. J Endotoxin Res 2007 0.78
103 Ivabradine in combination with beta-blocker therapy for the treatment of stable angina pectoris in every day clinical practice. Clin Res Cardiol 2010 0.78
104 Cholesteryl ester transfer protein activity and cardiovascular events in patients with chronic kidney disease stage V. Nephrol Dial Transplant 2008 0.78
105 Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy. Mol Med 2008 0.78
106 Association of health behaviour with heart rate variability: a population-based study. BMC Cardiovasc Disord 2010 0.78
107 A novel approach for transcoronary pacing in a porcine model. J Invasive Cardiol 2012 0.78
108 Optimizing of transcoronary pacing in a porcine model. J Invasive Cardiol 2009 0.77
109 Beta-blockade does not alter plasma cytokine concentrations and ventricular function in young adults with right ventricular dysfunction secondary to operated congenital heart disease. Circ J 2008 0.77
110 In-vitro comparison of fondaparinux, unfractionated heparin, and enoxaparin in preventing cardiac catheter-associated thrombus. Coron Artery Dis 2008 0.77
111 Argatroban and bivalirudin compared to unfractionated heparin in preventing thrombus formation on mechanical heart valves. Results of an in-vitro study. Thromb Haemost 2009 0.77
112 INR matters: a case on managing argatroban for bridging oral anticoagulation in a patient with heparin induced thrombocytopenia type II after mechanical heart valve replacement. Thromb Res 2008 0.77
113 Efficacy of enoxaparin, certoparin and dalteparin in preventing cardiac catheter thrombosis: an in vitro approach. J Thromb Thrombolysis 2010 0.77
114 Sex-specific associations between thyrotropin and serum lipid profiles. Thyroid 2013 0.77
115 Serum phospholipid transfer protein activity after a high fat meal in patients with insulin-treated type 2 diabetes. Lipids 2010 0.77
116 Neutrophil adherence to activated saphenous vein and mammary endothelium after graft preparation. Ann Thorac Surg 2006 0.76
117 Analysis of complex physiological systems by information flow: a time scale-specific complexity assessment. Biomed Tech (Berl) 2006 0.76
118 Thyroid analytes TSH, FT3 and FT4 in serum of healthy elderly subjects as measured by the Roche modular system: do we need age and gender dependent reference levels? Clin Lab 2014 0.76
119 The alteration of autonomic function in multiple organ dysfunction syndrome. Crit Care Clin 2008 0.76
120 Immunoglobulin treatment in sepsis--is the answer "no"? Crit Care Med 2006 0.76
121 Ivabradine in combination with beta-blocker reduces symptoms and improves quality of life in elderly patients with stable angina pectoris: age-related results from the ADDITIONS study. Exp Gerontol 2014 0.76
122 Comparison of bivalirudin, enoxaparin, and unfractionated heparin in preventing cardiac catheter thrombosis. Results of an in-vitro study. Thromb Haemost 2008 0.76
123 Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity. Intensive Care Med 2004 0.76
124 Non-compaction cardiomyopathy with diffuse left coronary artery fistulae as a rare cause of congestive heart failure. Eur Heart J 2012 0.76
125 ACE-inhibitor therapy and survival among patients with multiorgan dysfunction syndrome (MODS) of cardiac and non-cardiac origin. Int J Cardiol 2009 0.76
126 Effect of inflammatory mediators on cardiovascular function. Curr Opin Crit Care 2016 0.76
127 Elevated troponin in septic patients in the emergency department: frequency, causes, and prognostic implications. Clin Res Cardiol 2014 0.75
128 Assessment of vagal activity during transcutaneous vagus nerve stimulation in mice. Crit Care Med 2008 0.75
129 Intra-aortic balloon counterpulsation in septic shock--really? Crit Care Med 2009 0.75
130 Secondary prevention following myocardial infarction--there is still more to be done. Dtsch Arztebl Int 2011 0.75
131 Evaluation of medical emergency rooms. Dtsch Arztebl Int 2010 0.75
132 The investigation of syncope: strengths and weaknesses of emergency medicine. Dtsch Arztebl Int 2012 0.75
133 Do not get in RAGE in cardiogenic shock: it is detrimental! Crit Care Med 2012 0.75
134 [Intensive care medicine 2004]. Med Klin (Munich) 2004 0.75
135 Massive ascites generation following pacemaker infection: a case report. Clin Res Cardiol 2011 0.75
136 [Required monitoring in the intensive care unit]. Herz 2006 0.75
137 Reducing Elevated Heart Rates in Patients with Multiple Organ Dysfunction Syndrome with the If (Funny Channel Current) Inhibitor Ivabradine. Shock 2017 0.75
138 ADP receptor antagonists in patients with acute myocardial infarction complicated by cardiogenic shock: a post hoc IABP-SHOCK II trial subgroup analysis. EuroIntervention 2016 0.75
139 Cytokines in chronic heart failure: possible interaction in the neurohormonal and the cytokine system at the cAMP level? Eur Cytokine Netw 2003 0.75
140 Genetic variants in TNFα and the one-year cardiovascular outcome in patients with coronary heart disease. Int J Cardiol 2013 0.75
141 Transesophageal echocardiographic image of a thrombus crossing a persistent foramen ovale from the right into the left atrium. J Am Soc Echocardiogr 2005 0.75
142 In memoriam of Dr. Heinz Rupp: associate editor of the Canadian Journal of Physiology and Pharmacology. Can J Physiol Pharmacol 2014 0.75
143 Positive impact of the β-blocker celiprolol on panic, anxiety, and cardiovascular parameters in patients with mitral valve prolapse syndrome. J Clin Psychopharmacol 2011 0.75
144 Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in mice. J Mol Cell Cardiol 2008 0.75
145 Detection of a left atrial thrombus under fondaparinux treatment: a case report. Curr Drug Saf 2011 0.75
146 A late presentation of giant traumatic pulmonary artery aneurysm. Circulation 2010 0.75
147 [Update cardiogenic shock]. Dtsch Med Wochenschr 2016 0.75
148 In vitro comparison of the novel, dual-acting FIIa/FXa-inhibitor EP217609C101, unfractionated heparin, enoxaparin, and fondaparinux in preventing cardiac catheter thrombosis. J Thromb Thrombolysis 2014 0.75
149 Transcoronary mapping of ventricular asynchrony due to left bundle branch block in a porcine model. J Invasive Cardiol 2014 0.75
150 Atypical course of a persistent left superior vena cava through the left atrium. Eur J Echocardiogr 2011 0.75
151 The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload. Mol Cell Biochem 2002 0.75
152 Attenuated autonomic function in multiple organ dysfunction syndrome across three age groups. Biomed Tech (Berl) 2006 0.75