|
1
|
A critical reassessment of the role of mitochondria in tumorigenesis.
|
PLoS Med
|
2005
|
1.96
|
|
2
|
Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels.
|
Neuron
|
2007
|
1.84
|
|
3
|
Association of ESR1 gene tagging SNPs with breast cancer risk.
|
Hum Mol Genet
|
2009
|
1.58
|
|
4
|
Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects.
|
Hum Mutat
|
2003
|
1.54
|
|
5
|
TGFβ1 SNPs and radio-induced toxicity in prostate cancer patients.
|
Radiother Oncol
|
2012
|
1.49
|
|
6
|
The average cumulative risks of breast and ovarian cancer for carriers of mutations in BRCA1 and BRCA2 attending genetic counseling units in Spain.
|
Clin Cancer Res
|
2008
|
1.43
|
|
7
|
The breast cancer low-penetrance allele 1100delC in the CHEK2 gene is not present in Spanish familial breast cancer population.
|
Int J Cancer
|
2004
|
1.24
|
|
8
|
Establishment of a Radiogenomics Consortium.
|
Int J Radiat Oncol Biol Phys
|
2010
|
1.23
|
|
9
|
Multiplex SNaPshot for detection of BRCA1/2 common mutations in Spanish and Spanish related breast/ovarian cancer families.
|
BMC Med Genet
|
2007
|
1.19
|
|
10
|
Is mitochondrial DNA variation associated with sporadic breast cancer risk?
|
Cancer Res
|
2008
|
1.18
|
|
11
|
Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes.
|
Hum Genet
|
2005
|
1.13
|
|
12
|
Characterization of BRCA1 and BRCA2 splicing variants: a collaborative report by ENIGMA consortium members.
|
Breast Cancer Res Treat
|
2011
|
1.11
|
|
13
|
Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.
|
J Med Genet
|
2012
|
1.04
|
|
14
|
Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer.
|
Clin Chem
|
2006
|
1.03
|
|
15
|
Detection of a large rearrangement in PALB2 in Spanish breast cancer families with male breast cancer.
|
Breast Cancer Res Treat
|
2011
|
1.03
|
|
16
|
Over-representation of two specific haplotypes among chromosomes harbouring BRCA1 mutations.
|
Eur J Hum Genet
|
2003
|
1.02
|
|
17
|
Radiogenomics: the search for genetic predictors of radiotherapy response.
|
Future Oncol
|
2014
|
1.01
|
|
18
|
Investigating the role of mitochondrial haplogroups in genetic predisposition to meningococcal disease.
|
PLoS One
|
2009
|
1.01
|
|
19
|
Comparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testing.
|
Clin Chem
|
2013
|
1.01
|
|
20
|
Mutation spectra of ABCC8 gene in Spanish patients with Hyperinsulinism of Infancy (HI).
|
Hum Mutat
|
2006
|
1.00
|
|
21
|
Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer.
|
Radiother Oncol
|
2013
|
0.99
|
|
22
|
High mitochondrial DNA stability in B-cell chronic lymphocytic leukemia.
|
PLoS One
|
2009
|
0.99
|
|
23
|
Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers.
|
Breast Cancer Res Treat
|
2009
|
0.97
|
|
24
|
Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations?
|
BMC Med Genet
|
2009
|
0.94
|
|
25
|
Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk.
|
Br J Haematol
|
2010
|
0.93
|
|
26
|
Analysis of PALB2 gene in BRCA1/BRCA2 negative Spanish hereditary breast/ovarian cancer families with pancreatic cancer cases.
|
PLoS One
|
2013
|
0.92
|
|
27
|
Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients.
|
Radiother Oncol
|
2012
|
0.92
|
|
28
|
Evaluation of a 5-tier scheme proposed for classification of sequence variants using bioinformatic and splicing assay data: inter-reviewer variability and promotion of minimum reporting guidelines.
|
Hum Mutat
|
2013
|
0.91
|
|
29
|
International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation.
|
Breast Cancer Res Treat
|
2010
|
0.91
|
|
30
|
Annular elastolytic giant cell granuloma associated to late-onset X-linked dominant protoporphyria.
|
Dermatology
|
2013
|
0.90
|
|
31
|
Evaluation of rare variants in the new fanconi anemia gene ERCC4 (FANCQ) as familial breast/ovarian cancer susceptibility alleles.
|
Hum Mutat
|
2013
|
0.88
|
|
32
|
Indian signatures in the westernmost edge of the European Romani diaspora: new insight from mitogenomes.
|
PLoS One
|
2013
|
0.88
|
|
33
|
No evidence of association between common European mitochondrial DNA variants in Alzheimer, Parkinson, and migraine in the Spanish population.
|
Am J Med Genet B Neuropsychiatr Genet
|
2014
|
0.88
|
|
34
|
Ligneous conjunctivitis: a clinicopathological, immunohistochemical, and genetic study including the treatment of two sisters with multiorgan involvement.
|
Virchows Arch
|
2007
|
0.88
|
|
35
|
Breast cancer genes: beyond BRCA1 and BRCA2.
|
Front Biosci (Landmark Ed)
|
2013
|
0.88
|
|
36
|
In vivo functional analysis of the counterbalance of hyperactive phosphatidylinositol 3-kinase p110 catalytic oncoproteins by the tumor suppressor PTEN.
|
Cancer Res
|
2007
|
0.87
|
|
37
|
The variant E233G of the RAD51D gene could be a low-penetrance allele in high-risk breast cancer families without BRCA1/2 mutations.
|
Int J Cancer
|
2004
|
0.84
|
|
38
|
Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families.
|
Eur J Hum Genet
|
2012
|
0.84
|
|
39
|
Characterization of TGM1 c.984+1G>A mutation identified in a homozygous carrier of lamellar ichthyosis.
|
Int J Dermatol
|
2012
|
0.83
|
|
40
|
BRCA1 mutations do not increase prostate cancer risk: results from a meta-analysis including new data.
|
Prostate
|
2011
|
0.82
|
|
41
|
Multiple local and recent founder effects of TGM1 in Spanish families.
|
PLoS One
|
2012
|
0.82
|
|
42
|
RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.
|
Breast Cancer Res Treat
|
2014
|
0.81
|
|
43
|
About 1% of the breast and ovarian Spanish families testing negative for BRCA1 and BRCA2 are carriers of RAD51D pathogenic variants.
|
Int J Cancer
|
2014
|
0.80
|
|
44
|
Limited family structure and triple-negative breast cancer (TNBC) subtype as predictors of BRCA mutations in a genetic counseling cohort of early-onset sporadic breast cancers.
|
Breast Cancer Res Treat
|
2014
|
0.77
|
|
45
|
Haplotype and quantitative transcript analyses of Portuguese breast/ovarian cancer families with the BRCA1 R71G founder mutation of Galician origin.
|
Fam Cancer
|
2009
|
0.76
|
|
46
|
The 'Pokemon' (ZBTB7) Gene: No Evidence of Association with Sporadic Breast Cancer.
|
Clin Med Oncol
|
2008
|
0.75
|