PubRank

C Oliver Kappe

Author PubWeight™ 82.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microwave-assisted synthesis of colloidal inorganic nanocrystals. Angew Chem Int Ed Engl 2011 1.55
2 Continuous flow organic synthesis under high-temperature/pressure conditions. Chem Asian J 2010 1.43
3 Microwave-assisted synthesis in water as solvent. Chem Rev 2007 1.36
4 The Liebeskind-Srogl C-C cross-coupling reaction. Angew Chem Int Ed Engl 2009 1.17
5 Nonthermal microwave effects revisited: on the importance of internal temperature monitoring and agitation in microwave chemistry. J Org Chem 2007 1.14
6 Microwave chemistry in silicon carbide reaction vials: separating thermal from nonthermal effects. Angew Chem Int Ed Engl 2009 1.13
7 PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes. Proc Natl Acad Sci U S A 2011 1.00
8 Rapid solid-phase synthesis of a calmodulin-binding peptide using controlled microwave irradiation. Nat Protoc 2007 0.98
9 Heterogeneous versus homogeneous palladium catalysts for ligandless mizoroki-heck reactions: a comparison of batch/microwave and continuous-flow processing. Chemistry 2009 0.97
10 Rapid nickel-catalyzed Suzuki-Miyaura cross-couplings of aryl carbamates and sulfamates utilizing microwave heating. J Org Chem 2011 0.96
11 One-pot, multicomponent route to pyrazoloquinolizinones. Org Lett 2007 0.95
12 On the importance of simultaneous infrared/fiber-optic temperature monitoring in the microwave-assisted synthesis of ionic liquids. Org Biomol Chem 2009 0.94
13 Microwave-enhanced and metal-catalyzed functionalizations of the 4-aryl-dihydropyrimidone template. J Comb Chem 2005 0.94
14 Heterogeneous catalytic hydrogenation reactions in continuous-flow reactors. ChemSusChem 2011 0.94
15 High-throughput microwave-assisted organic synthesis: moving from automated sequential to parallel library-generation formats in silicon carbide microtiter plates. J Comb Chem 2007 0.92
16 Microwave-assisted synthesis involving immobilized catalysts. Top Curr Chem 2004 0.92
17 Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis. Nat Protoc 2007 0.91
18 Automated generation of a dihydropyrimidine compound library using microwave-assisted processing. Nat Protoc 2007 0.90
19 Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. J Med Chem 2010 0.90
20 Solid-phase synthesis of difficult peptide sequences at elevated temperatures: a critical comparison of microwave and conventional heating technologies. J Org Chem 2008 0.89
21 Microwave-assisted high-throughput acid hydrolysis in silicon carbide microtiter platforms--a rapid and low volume sample preparation technique for total amino acid analysis in proteins and peptides. J Chromatogr A 2010 0.89
22 Microwave-assisted solution- and solid-phase synthesis of 2-amino-4-arylpyrimidine derivatives. J Comb Chem 2007 0.88
23 Tunable carbon-carbon and carbon-sulfur cross-coupling of boronic acids with 3,4-dihydropyrimidine-2-thiones. Org Lett 2004 0.88
24 A unified mechanistic view on the Morita-Baylis-Hillman reaction: computational and experimental investigations. J Org Chem 2010 0.87
25 Silicon carbide passive heating elements in microwave-assisted organic synthesis. J Org Chem 2006 0.87
26 Activation and deactivation of a chemical transformation by an electromagnetic field: evidence for specific microwave effects in the formation of Grignard reagents. Angew Chem Int Ed Engl 2011 0.87
27 Reply to the Correspondence on microwave effects in organic synthesis. Angew Chem Int Ed Engl 2013 0.87
28 Tuning of chemo- and regioselectivities in multicomponent condensations of 5-aminopyrazoles, dimedone, and aldehydes. J Org Chem 2008 0.87
29 Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment. J Org Chem 2012 0.87
30 Heterogeneous hydrogenation reactions using a continuous flow high pressure device. J Comb Chem 2005 0.86
31 The application of "click chemistry" for the decoration of 2(1H)-pyrazinone scaffold: generation of templates. J Comb Chem 2005 0.86
32 Microwave-assisted three-component synthesis of 7-aryl-2-alkylthio-4,7-dihydro-1,2,4-triazolo[1,5-a]-pyrimidine-6-carboxamides and their selective reduction. J Comb Chem 2006 0.85
33 Palladium-catalyzed direct arylation of heteroaromatic compounds: improved conditions utilizing controlled microwave heating. J Org Chem 2011 0.85
34 Kinetic resolution of rac-1-phenylethanol with immobilized lipases: a critical comparison of microwave and conventional heating protocols. J Org Chem 2009 0.85
35 Direct solid-phase synthesis of the beta-amyloid (1-42) peptide using controlled microwave heating. J Org Chem 2010 0.85
36 Synthesis of 5-substituted 1H-tetrazoles from nitriles and hydrazoic acid by using a safe and scalable high-temperature microreactor approach. Angew Chem Int Ed Engl 2010 0.85
37 Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow. ChemSusChem 2014 0.84
38 Microwave-assisted Negishi and Kumada cross-coupling reactions of aryl chlorides. Chem Commun (Camb) 2004 0.84
39 Understanding microwave heating effects in single mode type cavities-theory and experiment. Phys Chem Chem Phys 2010 0.84
40 Continuous flow synthesis of α-halo ketones: essential building blocks of antiretroviral agents. J Org Chem 2014 0.84
41 Palladium(0)-catalyzed, copper(I)-mediated coupling of boronic acids with cyclic thioamides. selective carbon-carbon bond formation for the functionalization of heterocycles. J Org Chem 2007 0.83
42 5-aroyl-3,4-dihydropyrimidin-2-one library generation via automated sequential and parallel microwave-assisted synthesis techniques. J Comb Chem 2007 0.83
43 Microwave-assisted ring-closing metathesis revisited. On the question of the nonthermal microwave effect. J Org Chem 2003 0.83
44 High-speed microwave-assisted synthesis of the trifluoromethylpyrazol-derived canonical transient receptor potential (TRPC) channel inhibitor Pyr3. ChemMedChem 2009 0.83
45 Sintered silicon carbide: a new ceramic vessel material for microwave chemistry in single-mode reactors. Chemistry 2010 0.83
46 Continuous flow generation and reactions of anhydrous diazomethane using a Teflon AF-2400 tube-in-tube reactor. Org Lett 2013 0.83
47 Microwave-assisted and continuous flow multistep synthesis of 4-(pyrazol-1-yl)carboxanilides. J Org Chem 2011 0.82
48 Combining Biginelli multicomponent and click chemistry: generation of 6-(1,2,3-triazol-1-yl)-dihydropyrimidone libraries. J Comb Chem 2004 0.82
49 Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols. J Proteomics 2012 0.82
50 On the energy efficiency of microwave-assisted organic reactions. ChemSusChem 2008 0.82
51 Continuous flow ozonolysis in a laboratory scale reactor. Org Lett 2011 0.82
52 The microwave-to-flow paradigm: translating high-temperature batch microwave chemistry to scalable continuous-flow processes. Chemistry 2011 0.82
53 Microwave-assisted cross-coupling and hydrogenation chemistry by using heterogeneous transition-metal catalysts: an evaluation of the role of selective catalyst heating. Chemistry 2009 0.82
54 In situ preparation of silver nanocomposites on cellulosic fibers--microwave vs. conventional heating. Carbohydr Polym 2013 0.81
55 The effect of pressure on microwave-enhanced Diels-Alder reactions. A case study. Org Biomol Chem 2003 0.81
56 Microwave-assisted asymmetric organocatalysis. A probe for nonthermal microwave effects and the concept of simultaneous cooling. J Org Chem 2007 0.81
57 A TRPC3 blocker, ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (Pyr3), prevents stent-induced arterial remodeling. J Pharmacol Exp Ther 2012 0.80
58 Direct arylation of benzene with aryl bromides using high-temperature/high-pressure process windows: expanding the scope of C-H activation chemistry. Chemistry 2012 0.80
59 Microwave-assisted derivatization procedures for gas chromatography/mass spectrometry analysis. Mol Divers 2010 0.80
60 Parallel synthesis of an amide library based on the 6,8-dioxa-3-azabicyclo[3.2.1]octane scaffold by direct aminolysis of methyl esters. J Comb Chem 2007 0.80
61 Investigating the existence of nonthermal/specific microwave effects using silicon carbide heating elements as power modulators. J Org Chem 2008 0.80
62 Investigation of the formation of CuInS2 nanoparticles by the oleylamine route: comparison of microwave-assisted and conventional syntheses. Inorg Chem 2010 0.80
63 Enantioseparation of racemic 4-aryl-3,4-dihydro-2(1H)-pyrimidones on chiral stationary phases based on 3,5-dimethylanilides of N-(4-alkylamino-3,5-dinitro)benzoyl L-alpha-amino acids. Chirality 2003 0.80
64 Combinatorial synthesis of functionalized 1,3-thiazine libraries using a combined polymer-supported reagent/catch-and-release strategy. Angew Chem Int Ed Engl 2004 0.80
65 In situ generated iron oxide nanocrystals as efficient and selective catalysts for the reduction of nitroarenes using a continuous flow method. Angew Chem Int Ed Engl 2012 0.79
66 An algorithm for the deconvolution of mass spectroscopic patterns in isotope labeling studies. Evaluation for the hydrogen-deuterium exchange reaction in ketones. J Org Chem 2007 0.79
67 A continuous-flow protocol for light-induced benzylic fluorinations. J Org Chem 2014 0.79
68 Hydrazine-mediated reduction of nitro and azide functionalities catalyzed by highly active and reusable magnetic iron oxide nanocrystals. J Org Chem 2013 0.78
69 Diversity-oriented synthesis of dibenzoazocines and dibenzoazepines via a microwave-assisted intramolecular A(3)-coupling reaction. Org Lett 2010 0.78
70 Continuous-flow synthesis of CdSe quantum dots: a size-tunable and scalable approach. Chemistry 2013 0.78
71 A three step continuous flow synthesis of the biaryl unit of the HIV protease inhibitor Atazanavir. Org Biomol Chem 2013 0.78
72 A two-step continuous-flow synthesis of N-(2-aminoethyl)acylamides through ring-opening/hydrogenation of oxazolines. Chemistry 2011 0.78
73 High-speed microwave-promoted hetero-Diels-Alder reactions of 2(1H)-pyrazinones in ionic liquid doped solvents. J Org Chem 2002 0.78
74 Rapid solid-phase peptide synthesis using thermal and controlled microwave irradiation. J Pept Sci 2006 0.78
75 Microwave-assisted scavenging of electrophiles utilizing polymer-supported sequestration reagents. Application to the synthesis of N3-acylated dihydropyrimidine libraries. Mol Divers 2003 0.78
76 Shifting chemical equilibria in flow--efficient decarbonylation driven by annular flow regimes. Angew Chem Int Ed Engl 2014 0.78
77 Unusual behavior in the reactivity of 5-substituted-1H-tetrazoles in a resistively heated microreactor. Beilstein J Org Chem 2011 0.78
78 Rapid parallel synthesis of polymer-bound enones utilizing microwave-assisted solid-phase chemistry. J Comb Chem 2002 0.78
79 Parallel microwave chemistry in silicon carbide reactor platforms: an in-depth investigation into heating characteristics. Mol Divers 2009 0.78
80 Design and evaluation of improved magnetic stir bars for single-mode microwave reactors. Org Biomol Chem 2013 0.78
81 Rapid formation of triarylphosphines by microwave-assisted transition metal-catalyzed C-p cross-coupling reactions. Org Lett 2002 0.77
82 Microwave-assisted multistep synthesis of functionalized 4-arylquinolin-2(1H)-ones using palladium-catalyzed cross-coupling chemistry. J Org Chem 2005 0.77
83 In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins. Angew Chem Int Ed Engl 2013 0.77
84 Copper-catalyzed C-C coupling of thiol esters and boronic acids under aerobic conditions. Angew Chem Int Ed Engl 2008 0.77
85 Symmetrical bisquinolones via metal-catalyzed cross-coupling and homocoupling reactions. J Org Chem 2006 0.77
86 Stereoconservative Negishi arylation and alkynylation as an efficient approach to enantiopure 2,2'-diarylated 1,1'-binaphthyls. Chem Commun (Camb) 2004 0.77
87 Electromagnetic simulations of microwave heating experiments using reaction vessels made out of silicon carbide. Phys Chem Chem Phys 2010 0.76
88 Continuous flow reduction of artemisinic acid utilizing multi-injection strategies-closing the gap towards a fully continuous synthesis of antimalarial drugs. Chemistry 2015 0.76
89 Structure-activity relationships and molecular docking of novel dihydropyrimidine-based mitotic Eg5 inhibitors. ChemMedChem 2010 0.76
90 Palladium(0)-catalyzed, copper(i)-mediated coupling of cyclic thioamides with alkenylboronic acids, organostannanes, and siloxanes. J Org Chem 2009 0.76
91 Direct preparation of nitriles from carboxylic acids in continuous flow. J Org Chem 2013 0.76
92 Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study. Org Biomol Chem 2014 0.76
93 An evaluation of microwave-assisted derivatization procedures using hyphenated mass spectrometric techniques. J Chromatogr A 2009 0.76
94 High-throughput experimentation platform: parallel microwave chemistry in HPLC/GC vials. J Comb Chem 2009 0.76
95 Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis. Org Lett 2014 0.76
96 Parallel microwave synthesis of 2-styrylquinazolin-4(3H)-ones in a high-throughput platform using HPLC/GC vials as reaction vessels. J Comb Chem 2010 0.75
97 Simulating microwave chemistry in a resistance-heated autoclave made of semiconducting silicon carbide ceramic. Chemistry 2013 0.75
98 Anthropogenic reaction parameters--the missing link between chemical intuition and the available chemical space. Chem Soc Rev 2014 0.75
99 Synthesis of bisquinolone-based mono- and diphosphine ligands of the Aza-BINAP type. J Org Chem 2008 0.75
100 Synthesis of functionalized 1,3-thiazine libraries combining solid-phase synthesis and post-cleavage modification methods. Chemistry 2004 0.75
101 Microwave-assisted forced degradation using high-throughput microtiter platforms. J Pharm Biomed Anal 2011 0.75
102 A high-throughput platform for low-volume high-temperature/pressure sealed vessel solvent extractions. Anal Chim Acta 2011 0.75
103 Traceless solid-phase synthesis of bicyclic dihydropyrimidones using multidirectional cyclization cleavage. J Comb Chem 2002 0.75
104 A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines. Mol Divers 2003 0.75
105 Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats. Chemistry 2012 0.75
106 Microwave-enhanced transition metal-catalyzed decoration of 2(1H)-pyrazinone scaffolds. Mol Divers 2003 0.75
107 Microwaves have truly revolutionized "chemistry" in the kitchen. Mol Divers 2003 0.75
108 Microwave-assisted synthesis of CdSe quantum dots: can the electromagnetic field influence the formation and quality of the resulting nanocrystals? Nanoscale 2012 0.75
109 Continuous-flow synthesis of adipic acid from cyclohexene using hydrogen peroxide in high-temperature explosive regimes. ChemSusChem 2013 0.75
110 A scalable procedure for light-induced benzylic brominations in continuous flow. J Org Chem 2013 0.75
111 An investigation of wall effects in microwave-assisted ring-closing metathesis and cyclotrimerization reactions. J Org Chem 2010 0.75
112 A critical assessment of the specific role of microwave irradiation in the synthesis of ZnO micro- and nanostructured materials. Chemistry 2012 0.75
113 Microwave-assisted high-throughput derivatization techniques utilizing silicon carbide microtiter platforms. J Chromatogr A 2009 0.75
114 Preparation of thioamide building blocks via microwave-promoted three-component kindler reactions. J Comb Chem 2003 0.75
115 On the mechanism of the Dakin-West reaction. Org Biomol Chem 2012 0.75
116 High-throughput synthesis of N3-acylated dihydropyrimidines combining microwave-assisted synthesis and scavenging techniques. Org Lett 2003 0.75
117 Mechanistic insights on azide-nitrile cycloadditions: on the dialkyltin oxide-trimethylsilyl azide route and a new Vilsmeier-Haack-type organocatalyst. J Am Chem Soc 2011 0.75
118 An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions. J Org Chem 2012 0.75
119 Amphiphilic polymers based on higher alkylene oxides Synthesis and characterization by different chromatographic techniques. J Chromatogr A 2008 0.75