Published in Sci Signal on November 22, 2011
Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3. Nat Genet (2012) 1.53
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Claudin-14 underlies Ca⁺⁺-sensing receptor-mediated Ca⁺⁺ metabolism via NFAT-microRNA-based mechanisms. J Am Soc Nephrol (2013) 0.90
Decreased transcriptional activity of calcium-sensing receptor gene promoter 1 is associated with calcium nephrolithiasis. J Clin Endocrinol Metab (2013) 0.84
Engendering biased signalling from the calcium-sensing receptor for the pharmacotherapy of diverse disorders. Br J Pharmacol (2014) 0.84
Total calcium-sensing receptor expression in circulating monocytes is increased in rheumatoid arthritis patients with severe coronary artery calcification. Arthritis Res Ther (2014) 0.81
Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv (2016) 0.79
Determination and modulation of total and surface calcium-sensing receptor expression in monocytes in vivo and in vitro. PLoS One (2013) 0.77
Structural mechanism of ligand activation in human calcium-sensing receptor. Elife (2016) 0.77
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Cytoskeletal changes induced by allosteric modulators of calcium-sensing receptor in esophageal epithelial cells. Physiol Rep (2015) 0.76
Voltage Dependence of a Neuromodulator-Activated Ionic Current. eNeuro (2016) 0.76
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Calcium Sensing Receptor as a Novel Mediator of Adipose Tissue Dysfunction: Mechanisms and Potential Clinical Implications. Front Physiol (2016) 0.75
14-3-3 Proteins Buffer Intracellular Calcium Sensing Receptors to Constrain Signaling. PLoS One (2015) 0.75
Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer. Sci Rep (2017) 0.75
The Calcium-Sensing Receptor and the Parathyroid: Past, Present, Future. Front Physiol (2016) 0.75
Recent advances in understanding the extracellular calcium-sensing receptor. F1000Res (2016) 0.75
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. Mol Cell Biol (2003) 2.68
Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site. J Biol Chem (2003) 1.23
High affinity interaction with filamin A protects against calcium-sensing receptor degradation. J Biol Chem (2005) 1.16
Pharmacochaperone-mediated rescue of calcium-sensing receptor loss-of-function mutants. Mol Endocrinol (2009) 1.04
Generation of epitope-tagged proteins by inverse polymerase chain reaction mutagenesis. Methods Mol Biol (2002) 1.03
Rescue of calcium-sensing receptor mutants by allosteric modulators reveals a conformational checkpoint in receptor biogenesis. J Biol Chem (2007) 1.01
Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinct mechanisms: role of G protein-coupled receptor kinases, protein kinase C and beta-arrestins. Endocrinology (2007) 0.97
Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin. J Biol Chem (2006) 0.95
Calcium sensing receptor activation by a calcimimetic suggests a link between cooperativity and intracellular calcium oscillations. J Biol Chem (2002) 0.90
Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif. Cell Physiol Biochem (2010) 0.87
The cargo receptor p24A facilitates calcium sensing receptor maturation and stabilization in the early secretory pathway. Biochem Biophys Res Commun (2010) 0.86
Cellular calcium dynamics in lactation and breast cancer: from physiology to pathology. Am J Physiol Cell Physiol (2013) 0.84
Calcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retention. J Biol Chem (2010) 0.82
GIRK channels: hierarchy of control. Focus on "PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells". Am J Physiol Cell Physiol (2005) 0.80
Calcium signaling regulates trafficking of familial hypocalciuric hypercalcemia (FHH) mutants of the calcium sensing receptor. Mol Endocrinol (2012) 0.78
Human calcium-sensing receptor can be suppressed by antisense sequences. Biochem Biophys Res Commun (2003) 0.77
Beta-adrenergic receptors and Ca(2+). Focus on "Beta-adrenergic potentiation of endoplasmic reticulum Ca(2+) release in brown fat cells". Am J Physiol Cell Physiol (2002) 0.75
Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones. Adv Pharmacol (2011) 0.75