Published in Sci Am on November 01, 2011
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy. Sci Transl Med (2011) 2.56
Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species. Drug Metab Dispos (2003) 1.57
An extra quiet sun. Sci Am (2010) 1.38
Tissue disposition of 2'-O-(2-methoxy) ethyl modified antisense oligonucleotides in monkeys. J Pharm Sci (2004) 1.20
Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2'-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN. Biochem Pharmacol (2009) 0.95
Planets Everywhere. Systematic searches are revealing a plenitude of alien worlds. Sci Am (2012) 0.75
Sayonara, supergiant. Sci Am (2013) 0.75
Tensions over taikonauts. Sci Am (2012) 0.75
Laying odds on the apocalypse. Sci Am (2010) 0.75
Not too close for comfort. Sci Am (2013) 0.75
More mysterious methane. Sci Am (2009) 0.75
Damp rocks from space. Sci Am (2010) 0.75
A star's last breath: Supernova dust fell to earth in Antarctic meteorites. Sci Am (2013) 0.75
Stuff that designs itself. Self-assembling nanoparticles may be key to new materials. Sci Am (2012) 0.75
Gender gaps. Sci Am (2013) 0.75
Frothy physics. Sci Am (2013) 0.75
Anybody home? Sci Am (2013) 0.75
Fire and water. Sci Am (2012) 0.75
Mission: risk-averse. Sci Am (2013) 0.75
No star left behind. What fuels a white dwarf's luminous nuclear detonation? Sci Am (2012) 0.75
The dwindling web. Sci Am (2012) 0.75
A new wrinkle in time. Sci Am (2012) 0.75
Diamond planets. Sci Am (2013) 0.75
Shields up. Magnetized rock sets start of magnetic field closer to life. Sci Am (2010) 0.75
Preventing the next Chelyabinsk. Sci Am (2013) 0.75
Renewable energy's hidden costs. Sci Am (2013) 0.75
The last frontier. Sci Am (2012) 0.75
Lunar pencil lead. Sci Am (2010) 0.75
Closer to home. Sci Am (2013) 0.75
Buying a better bulb. Sci Am (2012) 0.75
Hawking was right (probably). Researchers may have re-created an elusive black hole phenomenon in the lab. Sci Am (2010) 0.75
Nobel pursuits: The tools of science have changed since the golden age of physics, but many of the same questions remain. Sci Am (2012) 0.75
Does infinity come in different sizes? Sci Am (2008) 0.75
Not set in stone (or ice). Sci Am (2009) 0.75
Feeling the heat. Sci Am (2011) 0.75
Tag--you're sick: patterns of personal contact in a hospital reveal true pathways of transmission. Sci Am (2012) 0.75
Space age wasteland. Debris in orbit is here to stay. Sci Am (2012) 0.75
12 events that will change everything. Sci Am (2010) 0.75
Ring theory. Sci Am (2013) 0.75
Swimming on Mars. The Red Planet may have once been home to an ocean. Sci Am (2012) 0.75
You are here. Sci Am (2012) 0.75
Filth in the spice rack. Imported seasonings are rife with all sorts of extras. Sci Am (2014) 0.75
Physics. Cloaking made simpler. Sci Am (2009) 0.75
Monopole position. Sci Am (2009) 0.75
High and dry in the food desert. Sci Am (2012) 0.75