Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.
|
N Engl J Med
|
2009
|
46.35
|
2
|
AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer.
|
N Engl J Med
|
2015
|
7.11
|
3
|
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer.
|
J Clin Oncol
|
2005
|
5.10
|
4
|
CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study.
|
Lancet Oncol
|
2013
|
4.30
|
5
|
Thoracic radiotherapy with or without daily low-dose carboplatin in elderly patients with non-small-cell lung cancer: a randomised, controlled, phase 3 trial by the Japan Clinical Oncology Group (JCOG0301).
|
Lancet Oncol
|
2012
|
2.03
|
6
|
Epidermal growth factor receptor mutation status in circulating free DNA in serum: from IPASS, a phase III study of gefitinib or carboplatin/paclitaxel in non-small cell lung cancer.
|
J Thorac Oncol
|
2012
|
1.86
|
7
|
Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort.
|
J Thorac Oncol
|
2011
|
1.71
|
8
|
Japanese-US common-arm analysis of paclitaxel plus carboplatin in advanced non-small-cell lung cancer: a model for assessing population-related pharmacogenomics.
|
J Clin Oncol
|
2009
|
1.61
|
9
|
A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer.
|
J Thorac Oncol
|
2008
|
1.53
|
10
|
EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan.
|
J Clin Oncol
|
2008
|
1.50
|
11
|
Randomized pharmacokinetic and pharmacodynamic study of docetaxel: dosing based on body-surface area compared with individualized dosing based on cytochrome P450 activity estimated using a urinary metabolite of exogenous cortisol.
|
J Clin Oncol
|
2005
|
1.50
|
12
|
Severe interstitial lung disease associated with amrubicin treatment.
|
J Thorac Oncol
|
2010
|
1.48
|
13
|
Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung.
|
Cancer Sci
|
2007
|
1.47
|
14
|
Influence of previous chemotherapy on the efficacy of subsequent docetaxel therapy in advanced non-small cell lung cancer patients.
|
J Thorac Oncol
|
2008
|
1.47
|
15
|
Detection of EGFR mutations in archived cytologic specimens of non-small cell lung cancer using high-resolution melting analysis.
|
Am J Clin Pathol
|
2006
|
1.36
|
16
|
Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non small cell lung cancer treated with gefitinib.
|
Clin Cancer Res
|
2007
|
1.34
|
17
|
Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer.
|
Clin Cancer Res
|
2008
|
1.31
|
18
|
Risk factors for interstitial lung disease and predictive factors for tumor response in patients with advanced non-small cell lung cancer treated with gefitinib.
|
Lung Cancer
|
2004
|
1.27
|
19
|
Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.
|
J Thorac Oncol
|
2014
|
1.19
|
20
|
Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes.
|
Carcinogenesis
|
2010
|
1.15
|
21
|
Tumor response to chemotherapy: the validity and reproducibility of RECIST guidelines in NSCLC patients.
|
Cancer Sci
|
2003
|
1.08
|
22
|
Clinical responses of large cell neuroendocrine carcinoma of the lung to cisplatin-based chemotherapy.
|
Lung Cancer
|
2005
|
1.06
|
23
|
Figitumumab combined with carboplatin and paclitaxel in treatment-naïve Japanese patients with advanced non-small cell lung cancer.
|
Invest New Drugs
|
2011
|
1.02
|
24
|
Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients.
|
Cancer Chemother Pharmacol
|
2009
|
1.01
|
25
|
Abrogation of the interaction between osteopontin and alphavbeta3 integrin reduces tumor growth of human lung cancer cells in mice.
|
Lung Cancer
|
2007
|
1.01
|
26
|
Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer.
|
J Clin Oncol
|
2010
|
1.00
|
27
|
Postmarketing surveillance study of erlotinib in Japanese patients with non-small-cell lung cancer (NSCLC): an interim analysis of 3488 patients (POLARSTAR).
|
J Thorac Oncol
|
2012
|
0.99
|
28
|
Proteomic signature corresponding to the response to gefitinib (Iressa, ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor in lung adenocarcinoma.
|
Clin Cancer Res
|
2007
|
0.99
|
29
|
Lung cancer working group report.
|
Jpn J Clin Oncol
|
2010
|
0.98
|
30
|
Genetic variations and frequencies of major haplotypes in SLCO1B1 encoding the transporter OATP1B1 in Japanese subjects: SLCO1B1*17 is more prevalent than *15.
|
Drug Metab Pharmacokinet
|
2007
|
0.97
|
31
|
Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer.
|
Cancer Sci
|
2009
|
0.96
|
32
|
Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung.
|
Pathol Int
|
2013
|
0.96
|
33
|
Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.
|
J Thorac Oncol
|
2011
|
0.96
|
34
|
Phase I study of cisplatin, vinorelbine, and concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer.
|
Cancer Sci
|
2004
|
0.95
|
35
|
Proteomic biomarkers for acute interstitial lung disease in gefitinib-treated Japanese lung cancer patients.
|
PLoS One
|
2011
|
0.94
|
36
|
Circulating endothelial cells in non-small cell lung cancer patients treated with carboplatin and paclitaxel.
|
J Thorac Oncol
|
2009
|
0.93
|
37
|
Epidermal growth factor receptor mutation, but not sex and smoking, is independently associated with favorable prognosis of gefitinib-treated patients with lung adenocarcinoma.
|
Cancer Sci
|
2008
|
0.93
|
38
|
Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.
|
Drug Metab Dispos
|
2008
|
0.91
|
39
|
Risk factors for treatment-related death associated with chemotherapy and thoracic radiotherapy for lung cancer.
|
J Thorac Oncol
|
2012
|
0.89
|
40
|
Phase III study comparing amrubicin plus cisplatin with irinotecan plus cisplatin in the treatment of extensive-disease small-cell lung cancer: JCOG 0509.
|
J Clin Oncol
|
2014
|
0.89
|
41
|
Characterization of the immunophenotype of the tumor budding and its prognostic implications in squamous cell carcinoma of the lung.
|
Lung Cancer
|
2011
|
0.89
|
42
|
Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma.
|
J Cancer Res Clin Oncol
|
2013
|
0.88
|
43
|
Renal toxicity caused by brand-name versus generic cisplatin: a comparative analysis.
|
Jpn J Clin Oncol
|
2013
|
0.88
|
44
|
Effect of platinum combined with irinotecan or paclitaxel against large cell neuroendocrine carcinoma of the lung.
|
Jpn J Clin Oncol
|
2007
|
0.88
|
45
|
Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients.
|
Br J Clin Pharmacol
|
2010
|
0.87
|
46
|
Osteopontin induces angiogenesis of murine neuroblastoma cells in mice.
|
Int J Cancer
|
2002
|
0.87
|
47
|
Risk factors for skeletal-related events in patients with non-small cell lung cancer treated by chemotherapy.
|
Lung Cancer
|
2008
|
0.87
|
48
|
Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens.
|
Lung Cancer
|
2011
|
0.86
|
49
|
Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study.
|
Jpn J Clin Oncol
|
2014
|
0.86
|
50
|
Retrospective analysis of steroid therapy for radiation-induced lung injury in lung cancer patients.
|
Radiother Oncol
|
2006
|
0.85
|
51
|
Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.
|
Drug Metab Dispos
|
2005
|
0.84
|
52
|
Safety and pharmacokinetic study of nab-paclitaxel plus carboplatin in chemotherapy-naïve patients with advanced non-small cell lung cancer.
|
Invest New Drugs
|
2011
|
0.84
|
53
|
Moderate renal dysfunction may not require a cisplatin dose reduction: a retrospective study of cancer patients with renal impairment.
|
Int J Clin Oncol
|
2012
|
0.84
|
54
|
Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients.
|
J Pharm Sci
|
2011
|
0.84
|
55
|
Functional analysis of four naturally occurring variants of human constitutive androstane receptor.
|
Mol Genet Metab
|
2005
|
0.83
|
56
|
Risk factors associated with fatal pulmonary hemorrhage in locally advanced non-small cell lung cancer treated with chemoradiotherapy.
|
BMC Cancer
|
2012
|
0.83
|
57
|
Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung.
|
J Cancer Res Clin Oncol
|
2013
|
0.83
|
58
|
Treatment of small cell lung cancer in the elderly based on a critical literature review of clinical trials.
|
Cancer Treat Rev
|
2004
|
0.82
|
59
|
Genetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population.
|
Drug Metab Pharmacokinet
|
2008
|
0.82
|
60
|
Final safety and efficacy of erlotinib in the phase 4 POLARSTAR surveillance study of 10 708 Japanese patients with non-small-cell lung cancer.
|
Cancer Sci
|
2014
|
0.81
|
61
|
Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation.
|
Pathol Int
|
2013
|
0.81
|
62
|
Pharmacokinetics and pharmacodynamics of weekly epoetin beta in lung cancer patients.
|
Jpn J Clin Oncol
|
2006
|
0.81
|
63
|
Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients.
|
Drug Metab Pharmacokinet
|
2009
|
0.81
|
64
|
Relation between elective nodal failure and irradiated volume in non-small-cell lung cancer (NSCLC) treated with radiotherapy using conventional fields and doses.
|
Radiother Oncol
|
2009
|
0.81
|
65
|
Phase II study of docetaxel and cisplatin administered as three consecutive weekly infusions for advanced non-small cell lung cancer.
|
Lung Cancer
|
2002
|
0.81
|
66
|
Clinical outcome of small cell lung cancer with pericardial effusion but without distant metastasis.
|
J Thorac Oncol
|
2011
|
0.80
|
67
|
Randomized phase 2 dose-finding study of weekly administration of darbepoetin alpha in anemic patients with lung or ovarian cancer receiving multicycle platinum-containing chemotherapy.
|
Jpn J Clin Oncol
|
2010
|
0.80
|
68
|
Genetic polymorphisms and haplotypes of por, encoding cytochrome p450 oxidoreductase, in a Japanese population.
|
Drug Metab Pharmacokinet
|
2010
|
0.80
|
69
|
Gender differences in treatment outcomes among patients with non-small cell lung cancer given a combination of carboplatin and paclitaxel.
|
Oncology
|
2008
|
0.80
|
70
|
Common arm analysis: one approach to develop the basis for global standardization in clinical trials of non-small cell lung cancer.
|
Lung Cancer
|
2006
|
0.80
|
71
|
CYP2C8 haplotype structures and their influence on pharmacokinetics of paclitaxel in a Japanese population.
|
Pharmacogenet Genomics
|
2007
|
0.80
|
72
|
Development of Cushing's syndrome during effective chemotherapy for small cell lung cancer.
|
Intern Med
|
2011
|
0.80
|
73
|
A dose-finding and pharmacokinetic study of nedaplatin in elderly patients with advanced non-small cell lung cancer.
|
Cancer Chemother Pharmacol
|
2009
|
0.80
|
74
|
Dose-escalation study of thoracic radiotherapy in combination with pemetrexed plus Cisplatin followed by pemetrexed consolidation therapy in Japanese patients with locally advanced nonsquamous non-small-cell lung cancer.
|
Clin Lung Cancer
|
2012
|
0.80
|
75
|
Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.
|
Cancer Chemother Pharmacol
|
2007
|
0.80
|
76
|
Brain metastases after definitive concurrent chemoradiotherapy in patients with stage III lung adenocarcinoma: carcinoembryonic antigen as a potential predictive factor.
|
Cancer Sci
|
2012
|
0.79
|
77
|
A phase I study of enzastaurin combined with pemetrexed in advanced non-small cell lung cancer.
|
J Thorac Oncol
|
2010
|
0.79
|
78
|
Genetic variations of VDR/NR1I1 encoding vitamin D receptor in a Japanese population.
|
Drug Metab Pharmacokinet
|
2007
|
0.79
|
79
|
Feasibility study of zoledronic acid plus cisplatin-docetaxel as first-line treatment for advanced non-small cell lung cancer with bone metastases.
|
Anticancer Res
|
2012
|
0.79
|
80
|
Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment.
|
Cancer Sci
|
2009
|
0.79
|
81
|
Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer.
|
Jpn J Clin Oncol
|
2004
|
0.79
|
82
|
Phase I/II study of 3-week cycle cisplatin-gemcitabine in advanced non-small cell lung cancer.
|
Jpn J Clin Oncol
|
2002
|
0.78
|
83
|
Phase I study of concurrent high-dose three-dimensional conformal radiotherapy with chemotherapy using cisplatin and vinorelbine for unresectable stage III non-small-cell lung cancer.
|
Int J Radiat Oncol Biol Phys
|
2011
|
0.78
|
84
|
Concurrent chemoradiotherapy for limited-disease small cell lung cancer in elderly patients aged 75 years or older.
|
Jpn J Clin Oncol
|
2007
|
0.78
|
85
|
Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.
|
Clin Pharmacol Ther
|
2006
|
0.78
|
86
|
Gender difference in treatment outcomes in patients with stage III non-small cell lung cancer receiving concurrent chemoradiotherapy.
|
Jpn J Clin Oncol
|
2009
|
0.78
|
87
|
Erlotinib in lung cancer.
|
N Engl J Med
|
2005
|
0.78
|
88
|
Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung.
|
J Cancer Res Clin Oncol
|
2015
|
0.78
|
89
|
Gender difference in hematological toxicity among lung cancer patients receiving amrubicin monotherapy.
|
Jpn J Clin Oncol
|
2012
|
0.78
|
90
|
Pharmacokinetic and pharmacodynamic study on amrubicin and amrubicinol in Japanese patients with lung cancer.
|
Cancer Chemother Pharmacol
|
2011
|
0.78
|
91
|
Antitumor activity of TZT-1027 (Soblidotin) against vascular endothelial growth factor-secreting human lung cancer in vivo.
|
Cancer Sci
|
2003
|
0.78
|
92
|
Comparative chemotherapeutic efficacy in non-small cell lung cancer patients with postoperative recurrence and stage IV disease.
|
J Thorac Oncol
|
2009
|
0.77
|
93
|
Phase I study of cisplatin analogue nedaplatin, paclitaxel, and thoracic radiotherapy for unresectable stage III non-small cell lung cancer.
|
Jpn J Clin Oncol
|
2007
|
0.77
|
94
|
Cancer-initiating cell marker-positive cells generate metastatic tumors that recapitulate the histology of the primary tumors.
|
Pathol Int
|
2013
|
0.77
|
95
|
Once-weekly epoetin-beta improves hemoglobin levels in cancer patients with chemotherapy-induced anemia: A randomized, double-blind, dose-finding study.
|
Jpn J Clin Oncol
|
2006
|
0.77
|
96
|
Study of paclitaxel and dose escalation of cisplatin in patients with advanced non-small cell lung cancer.
|
Jpn J Clin Oncol
|
2003
|
0.77
|
97
|
Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
|
Pharmacogenomics
|
2011
|
0.77
|
98
|
Comparison of the pharmacokinetics of erlotinib administered in complete fasting and 2 h after a meal in patients with lung cancer.
|
Cancer Chemother Pharmacol
|
2015
|
0.76
|
99
|
Safety and efficacy of platinum agents plus etoposide for patients with small cell lung cancer with interstitial lung disease.
|
Anticancer Res
|
2013
|
0.76
|
100
|
Surgical outcomes after initial surgery for clinical single-station N2 non-small-cell lung cancer.
|
Jpn J Clin Oncol
|
2013
|
0.76
|
101
|
Genetic variations and haplotype structures of the glutathione S-transferase genes, GSTT1 and GSTM1, in a Japanese patient population.
|
Drug Metab Pharmacokinet
|
2009
|
0.76
|
102
|
Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity.
|
Cancer Sci
|
2007
|
0.75
|
103
|
Three novel single nucleotide polymorphisms in UGT1A10.
|
Drug Metab Pharmacokinet
|
2002
|
0.75
|
104
|
Dose-Escalation Study of Thoracic Radiotherapy in Combination With Pemetrexed Plus Cisplatin in Japanese Patients With Locally Advanced Nonsquamous Non-Small Cell Lung Cancer: A Post Hoc Analysis of Survival and Recurrent Sites.
|
Am J Clin Oncol
|
2016
|
0.75
|
105
|
[Recent progress in the treatment of ED small cell lung cancer].
|
Nihon Rinsho
|
2002
|
0.75
|
106
|
Serum total bilirubin as a predictive factor for severe neutropenia in lung cancer patients treated with cisplatin and irinotecan.
|
Jpn J Clin Oncol
|
2007
|
0.75
|
107
|
Differences in the quality of information on the internet about lung cancer between the United States and Japan.
|
J Thorac Oncol
|
2009
|
0.75
|
108
|
Problems with registration-directed clinical trials for lung cancer in Japan.
|
Tohoku J Exp Med
|
2007
|
0.75
|
109
|
Enhanced antitumor activities of TZT-1027 against TNF-alpha or IL-6 secreting Lewis lung carcinoma in vivo.
|
Cancer Chemother Pharmacol
|
2002
|
0.75
|
110
|
A phase II study of hyperfractionated accelerated radiotherapy (HART) after induction cisplatin (CDDP) and vinorelbine (VNR) for stage III non-small-cell lung cancer (NSCLC).
|
Int J Radiat Oncol Biol Phys
|
2005
|
0.75
|
111
|
[Cancer treatment system and a new guideline for cancer treatment hospitals in Japan].
|
Nihon Rinsho
|
2015
|
0.75
|