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1
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Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
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Nat Genet
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2013
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7.44
|
|
2
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Vesicle trafficking: pleasure and pain from SM genes.
|
Trends Cell Biol
|
2003
|
2.60
|
|
3
|
Conformational switch of syntaxin-1 controls synaptic vesicle fusion.
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Science
|
2008
|
2.44
|
|
4
|
Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity.
|
Neuron
|
2007
|
2.32
|
|
5
|
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.
|
Science
|
2010
|
2.12
|
|
6
|
Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes.
|
Cell
|
2009
|
2.06
|
|
7
|
Fast vesicle fusion in living cells requires at least three SNARE complexes.
|
Science
|
2010
|
2.06
|
|
8
|
Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability.
|
Am J Hum Genet
|
2010
|
2.02
|
|
9
|
Munc18-1 in secretion: lonely Munc joins SNARE team and takes control.
|
Trends Neurosci
|
2007
|
1.96
|
|
10
|
Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission.
|
Neuron
|
2013
|
1.74
|
|
11
|
Dissecting docking and tethering of secretory vesicles at the target membrane.
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EMBO J
|
2006
|
1.70
|
|
12
|
Docking of secretory vesicles is syntaxin dependent.
|
PLoS One
|
2006
|
1.55
|
|
13
|
Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.
|
J Neurosci
|
2007
|
1.50
|
|
14
|
Automated analysis of neuronal morphology, synapse number and synaptic recruitment.
|
J Neurosci Methods
|
2010
|
1.36
|
|
15
|
Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size.
|
Proc Natl Acad Sci U S A
|
2006
|
1.35
|
|
16
|
Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies.
|
PLoS One
|
2010
|
1.26
|
|
17
|
Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.
|
J Neurochem
|
2005
|
1.21
|
|
18
|
Presynaptic signal transduction pathways that modulate synaptic transmission.
|
Curr Opin Neurobiol
|
2009
|
1.21
|
|
19
|
DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties.
|
J Neurochem
|
2006
|
1.12
|
|
20
|
Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.
|
EMBO J
|
2012
|
1.11
|
|
21
|
Multiple Ca2+ sensors in secretion: teammates, competitors or autocrats?
|
Trends Neurosci
|
2011
|
1.06
|
|
22
|
Matrix-dependent local retention of secretory vesicle cargo in cortical neurons.
|
J Neurosci
|
2009
|
1.03
|
|
23
|
Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain.
|
J Neurochem
|
2005
|
1.01
|
|
24
|
Somatodendritic secretion in oxytocin neurons is upregulated during the female reproductive cycle.
|
J Neurosci
|
2003
|
1.00
|
|
25
|
Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.
|
J Neurosci
|
2013
|
0.99
|
|
26
|
Trophic support delays but does not prevent cell-intrinsic degeneration of neurons deficient for munc18-1.
|
Eur J Neurosci
|
2004
|
0.98
|
|
27
|
Neurobeachin regulates neurotransmitter receptor trafficking to synapses.
|
J Cell Biol
|
2012
|
0.97
|
|
28
|
Differential involvement of the dorsal hippocampus in passive avoidance in C57bl/6J and DBA/2J mice.
|
Hippocampus
|
2008
|
0.97
|
|
29
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Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release.
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Elife
|
2014
|
0.96
|
|
30
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Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites.
|
Traffic
|
2006
|
0.95
|
|
31
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Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms.
|
J Biol Chem
|
2012
|
0.95
|
|
32
|
Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane.
|
J Biol Chem
|
2004
|
0.93
|
|
33
|
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity.
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Diabetes
|
2012
|
0.92
|
|
34
|
Dendritic position is a major determinant of presynaptic strength.
|
J Cell Biol
|
2012
|
0.89
|
|
35
|
The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1.
|
PLoS One
|
2007
|
0.89
|
|
36
|
Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.
|
Traffic
|
2010
|
0.88
|
|
37
|
Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.
|
PLoS One
|
2012
|
0.88
|
|
38
|
Munc18 and Munc13 regulate early neurite outgrowth.
|
Biol Cell
|
2010
|
0.87
|
|
39
|
Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner.
|
J Cell Biol
|
2014
|
0.87
|
|
40
|
Automated quantification of cellular traffic in living cells.
|
J Neurosci Methods
|
2008
|
0.86
|
|
41
|
Finding the right motivation: genotype-dependent differences in effective reinforcements for spatial learning.
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Behav Brain Res
|
2011
|
0.85
|
|
42
|
The role of Munc18-1 in docking and exocytosis of peptide hormone vesicles in the anterior pituitary.
|
Biol Cell
|
2005
|
0.85
|
|
43
|
Munc13 controls the location and efficiency of dense-core vesicle release in neurons.
|
J Cell Biol
|
2012
|
0.84
|
|
44
|
Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.
|
PLoS One
|
2011
|
0.84
|
|
45
|
TRIM3 regulates the motility of the kinesin motor protein KIF21B.
|
PLoS One
|
2013
|
0.84
|
|
46
|
A sequential vesicle pool model with a single release sensor and a Ca(2+)-dependent priming catalyst effectively explains Ca(2+)-dependent properties of neurosecretion.
|
PLoS Comput Biol
|
2013
|
0.82
|
|
47
|
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake.
|
Diabetologia
|
2014
|
0.81
|
|
48
|
Correction: CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.
|
Elife
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2015
|
0.80
|
|
49
|
Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release.
|
J Neurosci
|
2013
|
0.80
|
|
50
|
Bidirectional modulation of classical fear conditioning in mice by 5-HT(1A) receptor ligands with contrasting intrinsic activities.
|
Neuropharmacology
|
2009
|
0.80
|
|
51
|
Development of the mouse hypothalamo-neurohypophysial system in the munc18-1 null mutant that lacks regulated secretion.
|
Eur J Neurosci
|
2004
|
0.80
|
|
52
|
Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.
|
Brain Struct Funct
|
2014
|
0.80
|
|
53
|
Chronic activation of the 5-HT(2) receptor reduces 5-HT neurite density as studied in organotypic slice cultures.
|
Brain Res
|
2009
|
0.79
|
|
54
|
FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain.
|
PLoS One
|
2013
|
0.78
|
|
55
|
Within-strain variation in behavior differs consistently between common inbred strains of mice.
|
Mamm Genome
|
2015
|
0.77
|
|
56
|
Neurodegeneration: new road leads back to the synapse.
|
Neuron
|
2012
|
0.76
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57
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Genes encoding heterotrimeric G-proteins are associated with gray matter volume variations in the medial frontal cortex.
|
Cereb Cortex
|
2012
|
0.76
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58
|
Automated analysis of secretory vesicle distribution at the ultrastructural level.
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J Neurosci Methods
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2008
|
0.76
|
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59
|
Crashpilot underachieves due to acetylation at the nerve terminal.
|
Neuron
|
2011
|
0.75
|
|
60
|
Molecular machines in the synapse: overlapping protein sets control distinct steps in neurosecretion.
|
PLoS Comput Biol
|
2012
|
0.75
|
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61
|
Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate.
|
Elife
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2015
|
0.75
|