PubRank

Nir Hacohen

Author PubWeight™ 226.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nat Biotechnol 2011 53.86
2 Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009 35.48
3 A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 2006 18.81
4 SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011 11.07
5 Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 2013 9.24
6 Highly parallel identification of essential genes in cancer cells. Proc Natl Acad Sci U S A 2008 7.45
7 Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature 2013 6.50
8 Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science 2009 6.07
9 Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods 2006 5.96
10 Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol 2009 5.44
11 Peroxisomes are signaling platforms for antiviral innate immunity. Cell 2010 5.24
12 A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. Cell 2009 4.98
13 Genome-scale loss-of-function screening with a lentiviral RNAi library. Nat Methods 2006 4.12
14 Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells. Nat Biotechnol 2011 3.81
15 Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science 2008 3.17
16 Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory. Diabetes 2002 3.12
17 A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol Cell 2012 3.04
18 Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science 2014 2.77
19 Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science 2014 2.63
20 Synaptotagmin-mediated vesicle fusion regulates cell migration. Nat Immunol 2010 2.09
21 IAP inhibitors enhance co-stimulation to promote tumor immunity. J Exp Med 2010 2.07
22 Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. J Exp Med 2009 1.84
23 Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 2011 1.83
24 Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell Microbiol 2010 1.77
25 B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity 2012 1.70
26 Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion. Blood 2013 1.67
27 Principles and strategies for developing network models in cancer. Cell 2011 1.65
28 Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Mol Cell Proteomics 2012 1.58
29 The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. Immunity 2009 1.53
30 RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. Mol Biol Cell 2006 1.49
31 Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes. Nat Biotechnol 2015 1.47
32 Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. J Exp Med 2002 1.32
33 The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity. Nat Immunol 2013 1.29
34 Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov 2014 1.26
35 Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. J Exp Med 2014 1.25
36 Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity 2011 1.24
37 Strategies to discover regulatory circuits of the mammalian immune system. Nat Rev Immunol 2011 1.10
38 Immunology. Flow cytometry, amped up. Science 2011 1.06
39 MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties. J Immunol 2011 1.04
40 Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. J Clin Invest 2015 1.03
41 Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. Nat Biotechnol 2013 1.03
42 Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol 2012 1.02
43 Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia. Nano Lett 2012 1.01
44 Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans. J Clin Invest 2011 1.01
45 Carbohydrate-mediated targeting of antigen to dendritic cells leads to enhanced presentation of antigen to T cells. Chembiochem 2008 1.00
46 RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels. J Immunol 2009 0.98
47 TGF-β suppresses β-catenin-dependent tolerogenic activation program in dendritic cells. PLoS One 2011 0.94
48 Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells. PLoS One 2010 0.91
49 Systems biology approaches to dissect mammalian innate immunity. Curr Opin Immunol 2010 0.89
50 An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. Proc Natl Acad Sci U S A 2014 0.88
51 Forward RNAi screens in primary human hematopoietic stem/progenitor cells. Blood 2009 0.87
52 A role for Toll-like receptor 4 in dendritic cell activation and cytolytic CD8+ T cell differentiation in response to a recombinant heat shock fusion protein. J Immunol 2004 0.82
53 An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion. PLoS One 2011 0.81
54 Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches. Semin Immunol 2013 0.80
55 Semiconductor-based DNA sequencing of histone modification states. Nat Commun 2013 0.78
56 CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis. J Immunol 2014 0.76
57 RNAi screen for kinases and phosphatases that play a role in antigen presentation by dendritic cells. Eur J Immunol 2012 0.76