Published in Neuropsychopharmacology on January 01, 2012
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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol (2009) 2.72
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PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. Curr Biol (2003) 1.62
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Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis. J Clin Invest (2012) 1.45
Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells. Clin Cancer Res (2008) 1.43
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Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications. Biochemistry (2006) 1.36
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Ordered and disordered phases coexist in plasma membrane vesicles of RBL-2H3 mast cells. An ESR study. Biophys J (2003) 1.29
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Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem (2009) 1.10
Kinetic analysis of a mammalian phospholipase D: allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides. J Biol Chem (2005) 1.10
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Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry (2008) 1.08
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Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype. J Neurochem (2009) 1.01
Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells. Mol Pharmacol (2002) 1.01
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Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry. Nat Chem Biol (2010) 0.99
Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcepsilonRI. J Cell Sci (2003) 0.97
Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells. J Med Chem (2013) 0.95
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells. J Biol Chem (2013) 0.95
A hereditary bleeding disorder of dogs caused by a lack of platelet procoagulant activity. Blood (2002) 0.94
PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fc{gamma}-receptor-stimulated ROS production in neutrophils. J Cell Sci (2011) 0.93
Measurement of G protein-coupled receptor-stimulated phospholipase D activity in intact cells. Methods Mol Biol (2004) 0.93
Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. Blood (2007) 0.92
Sum of the parts: mass spectrometry-based metabolomics. Biochemistry (2013) 0.92
Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish. Dev Biol (2009) 0.92
A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. Mol Biol Cell (2014) 0.91
Extensive sphingolipid depletion does not affect lipid raft integrity or lipid raft localization and efflux function of the ABC transporter MRP1. Biochem J (2010) 0.90
Specificity of Rho insert-mediated activation of phospholipase D1. J Biol Chem (2002) 0.89
Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates. Mol Pharmacol (2009) 0.89
Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. J Lipid Res (2013) 0.87
Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116. Cell Rep (2013) 0.86
Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency. PLoS Genet (2013) 0.85
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem (2013) 0.84
Diacylglycerol kinase delta promotes lipogenesis. Biochemistry (2013) 0.84
Molecular species of phosphatidylinositol-cycle intermediates in the endoplasmic reticulum and plasma membrane. Biochemistry (2010) 0.83
Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation. J Biol Chem (2013) 0.82
Evidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry (2009) 0.81
Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strains. ChemMedChem (2014) 0.80
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Cobalt carbonyl complexes as probes for alkyne-tagged lipids. J Lipid Res (2013) 0.80
Biochemical characterization of a Pseudomonas aeruginosa phospholipase D. Biochemistry (2015) 0.78
Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes. ACS Chem Biol (2014) 0.77
Long term myriocin treatment increases MRP1 transport activity. Int J Biochem Cell Biol (2012) 0.77
Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2. J Leukoc Biol (2010) 0.75