Published in Angew Chem Int Ed Engl on December 08, 2011
A general strategy for organocatalytic activation of C-H bonds via photoredox catalysis: direct arylation of benzylic ethers. J Am Chem Soc (2013) 1.24
Synthetically tractable click hydrogels for three-dimensional cell culture formed using tetrazine-norbornene chemistry. Biomacromolecules (2013) 1.17
3D biofabrication strategies for tissue engineering and regenerative medicine. Annu Rev Biomed Eng (2014) 1.12
Synthesis and orthogonal photopatterning of hyaluronic acid hydrogels with thiol-norbornene chemistry. Biomaterials (2013) 1.01
Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cells. J Am Chem Soc (2012) 1.01
Activation of C-H bonds via the merger of photoredox and organocatalysis: a coupling of benzylic ethers with Schiff bases. J Am Chem Soc (2014) 1.01
Three-dimensional hMSC motility within peptide-functionalized PEG-based hydrogels of varying adhesivity and crosslinking density. Acta Biomater (2013) 0.98
Transition metal photoredox catalysis of radical thiol-ene reactions. J Org Chem (2012) 0.96
Hydrogels in Healthcare: From Static to Dynamic Material Microenvironments. Acta Mater (2013) 0.94
Progress in material design for biomedical applications. Proc Natl Acad Sci U S A (2015) 0.90
Covalently tethered transforming growth factor beta in PEG hydrogels promotes chondrogenic differentiation of encapsulated human mesenchymal stem cells. Drug Deliv Transl Res (2012) 0.88
Biomaterials and emerging anticancer therapeutics: engineering the microenvironment. Nat Rev Cancer (2015) 0.88
Mechanical Properties and Degradation of Chain and Step Polymerized Photodegradable Hydrogels. Macromolecules (2013) 0.87
Thiol-norbornene photo-click hydrogels for tissue engineering applications. J Appl Polym Sci (2015) 0.86
Recent advances in crosslinking chemistry of biomimetic poly(ethylene glycol) hydrogels. RSC Adv (2015) 0.86
In vitro models of tumor vessels and matrix: engineering approaches to investigate transport limitations and drug delivery in cancer. Adv Drug Deliv Rev (2013) 0.85
Photo-click living strategy for controlled, reversible exchange of biochemical ligands. Adv Mater (2014) 0.84
Covalently tethered TGF-β1 with encapsulated chondrocytes in a PEG hydrogel system enhances extracellular matrix production. J Biomed Mater Res A (2014) 0.84
Multiscale assembly for tissue engineering and regenerative medicine. Trends Biotechnol (2015) 0.84
Characterizing the effects of heparin gel stiffness on function of primary hepatocytes. Tissue Eng Part A (2013) 0.84
Synthetic mimics of the extracellular matrix: how simple is complex enough? Ann Biomed Eng (2015) 0.83
Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective. Adv Mater (2013) 0.82
Facile preparation of photodegradable hydrogels by photopolymerization. Polymer (Guildf) (2013) 0.81
Cardiac valve cells and their microenvironment--insights from in vitro studies. Nat Rev Cardiol (2014) 0.79
Bioactive hydrogels: Lighting the way. Nat Mater (2013) 0.78
Photoactive Electrospun Polymeric Meshes: Spatiotemporally Wetting of Textured 3-Dimensional Structures. J Mater Chem B Mater Biol Med (2014) 0.78
3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments. Dis Model Mech (2017) 0.78
Encoding Hydrogel Mechanics via Network Cross-Linking Structure. ACS Biomater Sci Eng (2015) 0.77
Materials science: Cell environments programmed with light. Nature (2012) 0.77
Dynamic three-dimensional micropatterned cell co-cultures within photocurable and chemically degradable hydrogels. J Tissue Eng Regen Med (2013) 0.77
Nano- and microstructured materials for in vitro studies of the physiology of vascular cells. Beilstein J Nanotechnol (2016) 0.77
Engineered Models of Confined Cell Migration. Annu Rev Biomed Eng (2016) 0.76
Strategies to balance covalent and non-covalent biomolecule attachment within collagen-GAG biomaterials. Biomater Sci (2014) 0.76
Creating biomaterials with spatially organized functionality. Exp Biol Med (Maywood) (2016) 0.75
Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes. Exp Biol Med (Maywood) (2016) 0.75
Dynamic 3D patterning of biochemical cues by using photoinduced bioorthogonal reactions. Angew Chem Int Ed Engl (2012) 0.75
In vitro selection technologies to enhance biomaterial functionality. Exp Biol Med (Maywood) (2016) 0.75
Dynamically Tunable Cell Culture Platforms for Tissue Engineering and Mechanobiology. Prog Polym Sci (2016) 0.75
Synthesis of non-linear protein dimers through a genetically encoded Thiol-ene reaction. PLoS One (2014) 0.75
Amplified Photodegradation of Cell-Laden Hydrogels via an Addition-Fragmentation Chain Transfer Reaction. Adv Mater (2017) 0.75
Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation. Adv Mater (2017) 0.75
Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science (2009) 5.68
Designing materials to direct stem-cell fate. Nature (2009) 4.86
Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng (2009) 4.72
Thiol-ene click chemistry. Angew Chem Int Ed Engl (2010) 4.42
Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65
Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts in vitro. J Biomater Sci Polym Ed (2000) 3.61
Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat Mater (2009) 3.29
A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization. Adv Mater (2009) 3.07
Materials science. Hydrogel cell cultures. Science (2007) 2.70
Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration. Biomaterials (2008) 2.23
Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions. Nat Chem (2011) 2.04
Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chem Mater (2010) 1.32
Endothelial cell guidance in 3D patterned scaffolds. Adv Mater (2010) 1.16
Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responses. Tissue Eng Part A (2010) 1.11
A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry. Tetrahedron Lett (2011) 0.96
Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science (2009) 5.68
Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng (2009) 4.72
Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials (2002) 4.45
Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. J Biomed Mater Res (2002) 3.47
Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat Mater (2009) 3.29
Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells. Nat Mater (2008) 3.24
Materials science. Hydrogel cell cultures. Science (2007) 2.70
Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility. Biomaterials (2009) 2.65
Synthetic hydrogel niches that promote hMSC viability. Matrix Biol (2005) 2.61
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res (2004) 2.45
PEG hydrogels for the controlled release of biomolecules in regenerative medicine. Pharm Res (2008) 2.44
In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials (2009) 2.41
Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage. J Biomed Mater Res A (2003) 2.37
Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A (2005) 2.17
Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions. Nat Chem (2011) 2.04
Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels. Biomaterials (2005) 2.02
Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production. Biotechnol Bioeng (2004) 1.97
Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms. Nat Protoc (2010) 1.92
The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials (2008) 1.82
Thiol-Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks. Macromolecules (2008) 1.81
Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng (2004) 1.79
The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation. Biomaterials (2006) 1.78
Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels. Biomaterials (2009) 1.77
The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels. Biomaterials (2011) 1.75
Photocrosslinking of gelatin macromers to synthesize porous hydrogels that promote valvular interstitial cell function. Tissue Eng Part A (2009) 1.67
Chondrogenic differentiation potential of human mesenchymal stem cells photoencapsulated within poly(ethylene glycol)-arginine-glycine-aspartic acid-serine thiol-methacrylate mixed-mode networks. Tissue Eng (2007) 1.66
In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels. J Biomed Mater Res A (2004) 1.66
Manipulations in hydrogel chemistry control photoencapsulated chondrocyte behavior and their extracellular matrix production. J Biomed Mater Res A (2003) 1.63
Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation. Acta Biomater (2005) 1.62
Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration. Biomaterials (2006) 1.61
Mechanical properties of cellularly responsive hydrogels and their experimental determination. Adv Mater (2010) 1.60
Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery. Biomaterials (2009) 1.56
Robust polymer microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP). Lab Chip (2004) 1.52
Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials (2005) 1.51
Nanobiomaterial applications in orthopedics. J Orthop Res (2007) 1.51
The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials (2007) 1.51
Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials (2009) 1.49
Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. Matrix Biol (2005) 1.49
Spatial and temporal control of the alkyne-azide cycloaddition by photoinitiated Cu(II) reduction. Nat Chem (2011) 1.48
Three-dimensional biochemical patterning of click-based composite hydrogels via thiolene photopolymerization. Biomacromolecules (2008) 1.46
Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. J Control Release (2002) 1.46
PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomater (2005) 1.46
Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A (2004) 1.43
The effect of ethylene glycol methacrylate phosphate in PEG hydrogels on mineralization and viability of encapsulated hMSCs. Biomaterials (2005) 1.42
Tunable hydrogels for external manipulation of cellular microenvironments through controlled photodegradation. Adv Mater (2010) 1.42
Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One (2012) 1.41
Cell-matrix interactions improve beta-cell survival and insulin secretion in three-dimensional culture. Tissue Eng Part A (2008) 1.40
Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing beta-cell function. Proc Natl Acad Sci U S A (2011) 1.38
Dexamethasone-functionalized gels induce osteogenic differentiation of encapsulated hMSCs. J Biomed Mater Res A (2006) 1.38
Encapsulating chondrocytes in copolymer gels: bimodal degradation kinetics influence cell phenotype and extracellular matrix development. J Biomed Mater Res A (2004) 1.37
Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. FASEB J (2008) 1.37
Macromolecular Monomers for the Synthesis of Hydrogel Niches and Their Application in Cell Encapsulation and Tissue Engineering. Prog Polym Sci (2008) 1.36
The influence of the RGD peptide motif and its contextual presentation in PEG gels on human mesenchymal stem cell viability. J Tissue Eng Regen Med (2008) 1.36
Degradable thiol-acrylate photopolymers: polymerization and degradation behavior of an in situ forming biomaterial. Biomaterials (2005) 1.34
Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet survival and function. J Biomed Mater Res A (2009) 1.34
Synthesis and characterization of photocrosslinkable, degradable poly(vinyl alcohol)-based tissue engineering scaffolds. Biomaterials (2002) 1.33
Delivering DNA from photocrosslinked, surface eroding polyanhydrides. J Control Release (2004) 1.32
Advances in bioactive hydrogels to probe and direct cell fate. Annu Rev Chem Biomol Eng (2012) 1.32
Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chem Mater (2010) 1.32
The effect on osteoblast function of colocalized RGD and PHSRN epitopes on PEG surfaces. Biomaterials (2005) 1.31
DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality. J Control Release (2004) 1.31
Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels. Acta Biomater (2004) 1.29
Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res (2004) 1.29
Substrate properties influence calcification in valvular interstitial cell culture. J Heart Valve Dis (2008) 1.28
Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels. Adv Funct Mater (2009) 1.26
A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration. Integr Biol (Camb) (2009) 1.25
Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion. Matrix Biol (2008) 1.23
Exogenously triggered, enzymatic degradation of photopolymerized hydrogels with polycaprolactone subunits: experimental observation and modeling of mass loss behavior. Biomacromolecules (2006) 1.21
Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A (2013) 1.20
Photoinitiated crosslinked degradable copolymer networks for tissue engineering applications. Biomaterials (2003) 1.19
Synthetically tractable click hydrogels for three-dimensional cell culture formed using tetrazine-norbornene chemistry. Biomacromolecules (2013) 1.17
Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition. Acta Biomater (2012) 1.16
Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol (2009) 1.16
Thiol-ene photopolymerizations provide a facile method to encapsulate proteins and maintain their bioactivity. Biomacromolecules (2012) 1.15
Tailoring the degradation of hydrogels formed from multivinyl poly(ethylene glycol) and poly(vinyl alcohol) macromers for cartilage tissue engineering. Biomacromolecules (2003) 1.12
Controlling cartilaginous matrix evolution in hydrogels with degradation triggered by exogenous addition of an enzyme. Tissue Eng (2007) 1.12
Enzyme-mediated redox initiation for hydrogel generation and cellular encapsulation. Biomacromolecules (2009) 1.12
Material-based regulation of the myofibroblast phenotype. Biomaterials (2007) 1.11
Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery. J Biomed Mater Res A (2012) 1.11
Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation. Tissue Eng (2006) 1.11
Gene delivery in tissue engineering: a photopolymer platform to coencapsulate cells and plasmid DNA. Pharm Res (2003) 1.11
Multifunctional hydrogels that promote osteogenic hMSC differentiation through stimulation and sequestering of BMP2. Adv Funct Mater (2007) 1.10
Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materials. Soft Matter (2010) 1.10
Glucagon-like peptide-1 functionalized PEG hydrogels promote survival and function of encapsulated pancreatic beta-cells. Biomacromolecules (2009) 1.10
Synthesis of immunoisolation barriers that provide localized immunosuppression for encapsulated pancreatic islets. Bioconjug Chem (2006) 1.09
Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems. Adv Mater (2013) 1.08
Kinetic chain lengths in highly cross-linked networks formed by the photoinitiated polymerization of divinyl monomers: a gel permeation chromatography investigation. Biomacromolecules (2003) 1.08
Gel Permeation Chromatography Characterization of the Chain Length Distributions in Thiol-Acrylate Photopolymer Networks. Macromolecules (2006) 1.07
The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells. Biomaterials (2008) 1.07
Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels. Biomacromolecules (2009) 1.07
Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge. Dev Cell (2013) 1.07
An initial investigation of photocurable three-dimensional lactic acid based scaffolds in a critical-sized cranial defect. Biomaterials (2003) 1.05
Hemodynamic and cellular response feedback in calcific aortic valve disease. Circ Res (2013) 1.05
Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A (2007) 1.05
Glucose oxidase-mediated polymerization as a platform for dual-mode signal amplification and biodetection. Biotechnol Bioeng (2011) 1.05
Dynamic microenvironments: the fourth dimension. Sci Transl Med (2012) 1.04
Regulating MCP-1 diffusion in affinity hydrogels for enhancing immuno-isolation. J Control Release (2009) 1.04
Photodegradable, Photoadaptable Hydrogels via Radical-Mediated Disulfide Fragmentation Reaction. Macromolecules (2011) 1.04
Controlling network structure in degradable thiol-acrylate biomaterials to tune mass loss behavior. Biomacromolecules (2006) 1.03
Functionalized PEG hydrogels through reactive dip-coating for the formation of immunoactive barriers. Biomaterials (2011) 1.03