Alisha R Elford

Author PubWeight™ 39.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. Cell 2011 3.61
2 Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo. Nat Med 2003 2.62
3 Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proc Natl Acad Sci U S A 2011 1.98
4 TCR affinity and negative regulation limit autoimmunity. Nat Med 2004 1.94
5 Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. Nat Med 2009 1.78
6 TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice. J Clin Invest 2007 1.63
7 Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection. J Exp Med 2011 1.60
8 Cellular FLICE-inhibitory protein is required for T cell survival and cycling. J Exp Med 2005 1.52
9 Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance. J Exp Med 2002 1.48
10 CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity. Proc Natl Acad Sci U S A 2008 1.48
11 Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. Mol Cell Biol 2005 1.26
12 CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. J Exp Med 2002 1.22
13 CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J Immunol 2007 1.18
14 A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. Science 2006 1.16
15 PKCtheta signals activation versus tolerance in vivo. J Exp Med 2004 1.15
16 NF-kappaB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis in vivo. J Immunol 2005 1.08
17 DNA damage- and stress-induced apoptosis occurs independently of PIDD. Apoptosis 2009 1.05
18 Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges. J Immunol 2012 1.05
19 Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells. Nat Med 2011 1.03
20 c-Rel but not NF-kappaB1 is important for T regulatory cell development. Eur J Immunol 2010 1.01
21 IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses. Eur J Immunol 2008 0.98
22 Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development. Eur J Immunol 2007 0.96
23 CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. Mol Cell Biol 2007 0.85
24 Targeting of pancreatic glia in type 1 diabetes. Diabetes 2008 0.85
25 Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch. J Immunol 2013 0.84
26 Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage. J Immunol 2009 0.83
27 Immunological perspective of self versus tumor antigens: insights from the RIP-gp model. Immunol Rev 2011 0.82
28 c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance. Eur J Immunol 2010 0.81
29 Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity. PLoS One 2011 0.79
30 Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death. Eur J Immunol 2010 0.78
31 In vivo generation of cytotoxic T cells from epitopes displayed on peptide-based delivery vehicles. J Immunol 2002 0.77