Published in Free Radic Biol Med on December 13, 2011
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury. Neurochem Int (2012) 0.99
Thioredoxin reductase and its inhibitors. Curr Protein Pept Sci (2014) 0.89
Multiple classes of environmental chemicals are associated with liver disease: NHANES 2003-2004. Int J Hyg Environ Health (2013) 0.87
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA. J Toxicol (2012) 0.86
Cerebrospinal fluid of newly diagnosed amyotrophic lateral sclerosis patients exhibits abnormal levels of selenium species including elevated selenite. Neurotoxicology (2013) 0.80
Thioredoxin system regulation in the central nervous system: experimental models and clinical evidence. Oxid Med Cell Longev (2014) 0.78
Biomarkers of adverse response to mercury: histopathology versus thioredoxin reductase activity. J Biomed Biotechnol (2012) 0.78
Oral exposure to methylmercury modifies the prostatic microenvironment in adult rats. Int J Exp Pathol (2012) 0.77
Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation. Protein Sci (2016) 0.75
Methylmercury Induced Neurotoxicity and the Influence of Selenium in the Brains of Adult Zebrafish (Danio rerio). Int J Mol Sci (2017) 0.75
Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury. Redox Biol (2017) 0.75
Subchronic toxicity of Nile tilapia with different exposure routes to Microcystis aeruginosa: Histopathology, liver functions, and oxidative stress biomarkers. Vet World (2017) 0.75
The toxic influence of dibromoacetic acid on the hippocampus and pre-frontal cortex of rat: involvement of neuroinflammation response and oxidative stress. Metab Brain Dis (2017) 0.75
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med (2002) 23.42
Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
Hypothalamic regulation of sleep and circadian rhythms. Nature (2005) 8.23
Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet (2009) 6.35
Altered microRNA expression in human heart disease. Physiol Genomics (2007) 5.64
Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21
Sleep state switching. Neuron (2010) 4.94
Thioredoxin and related molecules--from biology to health and disease. Antioxid Redox Signal (2007) 3.50
From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal (2007) 3.49
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology (2003) 3.19
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A (2008) 3.13
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10
Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid Redox Signal (2004) 3.04
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci U S A (2007) 3.00
The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells. Cell (2008) 2.94
Pathway level analysis of gene expression using singular value decomposition. BMC Bioinformatics (2005) 2.78
A broad role for melanopsin in nonvisual photoreception. J Neurosci (2003) 2.78
The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology (2011) 2.71
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat Immunol (2008) 2.70
Glutaredoxin systems. Biochim Biophys Acta (2008) 2.65
A preliminary report of penile transplantation. Eur Urol (2006) 2.54
MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci U S A (2010) 2.53
The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis (2014) 2.46
The thioredoxin system in cancer. Semin Cancer Biol (2006) 2.42
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev (2009) 2.41
Differential rescue of light- and food-entrainable circadian rhythms. Science (2008) 2.20
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol (2009) 2.18
Probing the chemistry of thioredoxin catalysis with force. Nature (2007) 2.17
Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci (2003) 2.15
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc Natl Acad Sci U S A (2007) 2.11
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization. Blood (2009) 2.11
Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochem Biophys Res Commun (2010) 2.09
Selenoproteins. J Biol Chem (2008) 2.02
Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems. Proc Natl Acad Sci U S A (2002) 2.00
Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol (2007) 2.00
Roads to polyploidy: the megakaryocyte example. J Cell Physiol (2002) 2.00
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. Am J Physiol Heart Circ Physiol (2006) 1.99
The hypothalamic integrator for circadian rhythms. Trends Neurosci (2005) 1.99
Reassessment of the structural basis of the ascending arousal system. J Comp Neurol (2011) 1.93
Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers. Proc Natl Acad Sci U S A (2004) 1.89
RNA catalyses nuclear pre-mRNA splicing. Nature (2013) 1.86
Afferents to the ventrolateral preoptic nucleus. J Neurosci (2002) 1.86
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J (2005) 1.86
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice. Gastroenterology (2010) 1.85
Thioredoxins and glutaredoxins as facilitators of protein folding. Biochim Biophys Acta (2008) 1.85
New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis (2002) 1.80
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus. Chem Biol (2011) 1.80
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. Sci Transl Med (2012) 1.80
Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis. Arch Biochem Biophys (2002) 1.78
A minimal domain responsible for Munc13 activity. Nat Struct Mol Biol (2005) 1.68
Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor. Proc Natl Acad Sci U S A (2005) 1.68
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta (2009) 1.66
Two-dimensional nanocrystals produced by exfoliation of Ti3 AlC2. Adv Mater (2011) 1.66
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. J Biol Chem (2005) 1.64
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell (2012) 1.61
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat Struct Mol Biol (2010) 1.58
The relationship between PTH and 25-hydroxy vitamin D early in pregnancy. Clin Endocrinol (Oxf) (2011) 1.56
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase. J Biol Chem (2003) 1.55
Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression. Proc Natl Acad Sci U S A (2008) 1.54
SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Res (2012) 1.50
A hierarchical model for estimating response time distributions. Psychon Bull Rev (2005) 1.50
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat Commun (2012) 1.49
The effect of repeated etomidate anesthesia on adrenocortical function during a course of electroconvulsive therapy. J ECT (2011) 1.49
Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity. Cancer Res (2006) 1.48
Exogenous surfactant may improve oxygenation but not mortality in adult patients with acute lung injury/acute respiratory distress syndrome: a meta-analysis of 9 clinical trials. J Cardiothorac Vasc Anesth (2012) 1.47
Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. J Biol Chem (2008) 1.45
Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg (2007) 1.44
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun (2013) 1.43
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. Proc Natl Acad Sci U S A (2010) 1.43
The pontine REM switch: past and present. J Physiol (2007) 1.42
An introduction to Bayesian hierarchical models with an application in the theory of signal detection. Psychon Bull Rev (2005) 1.42
Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53. EMBO J (2011) 1.42
Two-dimensional transition metal carbides. ACS Nano (2012) 1.42
Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One (2011) 1.41
Structure and function of the interacting domains of Spire and Fmn-family formins. Proc Natl Acad Sci U S A (2011) 1.36
Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys (2011) 1.33
Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase. J Biol Chem (2006) 1.33
Chemical enhancement of torsinA function in cell and animal models of torsion dystonia. Dis Model Mech (2010) 1.33
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest (2010) 1.33
Thioredoxin system in cell death progression. Antioxid Redox Signal (2012) 1.32
Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues. J Biol Chem (2008) 1.32
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nat Struct Mol Biol (2011) 1.32
Basal ganglia control of sleep-wake behavior and cortical activation. Eur J Neurosci (2010) 1.32
Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell (2010) 1.31
Chaperone properties of Escherichia coli thioredoxin and thioredoxin reductase. Biochem J (2003) 1.30
HDAC inhibitors: a potential new category of anti-tumor agents. Cell Mol Immunol (2007) 1.25
Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. J Am Chem Soc (2006) 1.25
Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. PLoS One (2009) 1.25
The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol (2006) 1.25
Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential. BMC Mol Biol (2007) 1.24
Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J (2012) 1.24
FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells. Breast Cancer Res Treat (2011) 1.22