New therapies in cystic fibrosis.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 22229570)

Published in Curr Pharm Des on January 01, 2012

Authors

Felix Ratjen1, Hartmut Grasemann

Author Affiliations

1: Division of Respiratory Medicine, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada. felix.ratjen@sickkids.ca

Articles by these authors

Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest (2010) 2.29

Innate immune collectin surfactant protein D simultaneously binds both neutrophil extracellular traps and carbohydrate ligands and promotes bacterial trapping. J Immunol (2011) 1.89

Diagnostic value of nasal nitric oxide measured with non-velum closure techniques for children with primary ciliary dyskinesia. J Pediatr (2011) 1.81

Longitudinal decline in lung volume in a population of children with sickle cell disease. Am J Respir Crit Care Med (2008) 1.73

Sputum induction in routine clinical care of children with cystic fibrosis. J Pediatr (2010) 1.67

beta2 adrenoceptor gene polymorphisms in cystic fibrosis lung disease. Pharmacogenetics (2002) 1.54

Lower airway nitric oxide is increased in children with sickle cell disease. J Pediatr (2011) 1.49

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma. Am J Physiol Lung Cell Mol Physiol (2009) 1.37

Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med (2011) 1.25

Interacting genetic loci cause airway hyperresponsiveness. Physiol Genomics (2005) 1.15

Akt is essential to induce NADPH-dependent NETosis and to switch the neutrophil death to apoptosis. Blood (2014) 1.00

Diagnostic value of serum antibodies in early Pseudomonas aeruginosa infection in cystic fibrosis patients. Pediatr Pulmonol (2007) 1.00

Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis. Pediatr Pulmonol (2008) 0.98

Influence of interleukin-10 on Aspergillus fumigatus infection in patients with cystic fibrosis. J Infect Dis (2005) 0.96

Role of respiratory viruses in pulmonary exacerbations in children with cystic fibrosis. J Cyst Fibros (2012) 0.96

Developmental changes in arginase expression and activity in the lung. Am J Physiol Lung Cell Mol Physiol (2008) 0.94

Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels. Am J Respir Crit Care Med (2003) 0.93

Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma. Respir Res (2011) 0.89

Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients. J Cyst Fibros (2011) 0.88

P2Y2 receptor polymorphisms and haplotypes in cystic fibrosis and their impact on Ca2+ influx. Pharmacogenet Genomics (2006) 0.88

Disease modifying genes in cystic fibrosis: therapeutic option or one-way road? Naunyn Schmiedebergs Arch Pharmacol (2006) 0.87

Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. Am J Respir Cell Mol Biol (2013) 0.87

Necrotizing pneumonia complicated by early and late pneumatoceles. Can Respir J (2008) 0.85

CFTR mutations in Turkish and North African cystic fibrosis patients in Europe: implications for screening. Genet Test (2008) 0.85

Cystic fibrosis: detecting changes in airway inflammation with FDG PET/CT. Radiology (2012) 0.84

Asymmetric dimethylarginine and asthma. Eur Respir J (2014) 0.81

Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. Free Radic Biol Med (2011) 0.80

The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction. J Allergy Clin Immunol (2012) 0.79

Human adenosine 2B receptor: SNP discovery and evaluation of expression in patients with cystic fibrosis. Pharmacogenet Genomics (2005) 0.79

A child with autoimmune polyendocrinopathy candidiasis and ectodermal dysplasia treated with immunosuppression: a case report. J Med Case Rep (2013) 0.78

Airway nitric oxide in Duchenne muscular dystrophy. J Pediatr (2002) 0.78

SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance. Orphanet J Rare Dis (2009) 0.78

Energy expenditure and nutritional status in pediatric patients before and after lung transplantation. J Pediatr (2013) 0.77

Chronic hypercapnia downregulates arginase expression and activity and increases pulmonary arterial smooth muscle relaxation in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2009) 0.77

Do the cysteine proteinases cathepsin B and S contribute to cystic fibrosis lung disease? Pediatr Pulmonol (2010) 0.77

Flow-independent exhaled nitric oxide parameters in pediatric lung and cardiac transplant recipients. Transplantation (2011) 0.75

Editorial: leukocyte trafficking and matrix metalloproteinase-8 in obliterative bronchiolitis. J Leukoc Biol (2010) 0.75

Gender-specific disease modification by NOS3. Br J Haematol (2004) 0.75

Arginine metabolism in patients with cystic fibrosis. J Pediatr (2013) 0.75

Index of suspicion. Pediatr Rev (2008) 0.75

Cardiopulmonary magnetic resonance imaging in children after lung transplantation: preliminary observations. J Heart Lung Transplant (2011) 0.75

New developments in pharmaceutical treatments for cystic fibrosis. Curr Pharm Des (2012) 0.75

Nasal nitric oxide is reduced in children after solid-organ transplantation. J Heart Lung Transplant (2010) 0.75