PubRank

Cosima T Baldari

Author PubWeight™ 61.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat Cell Biol 2009 2.94
2 Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. J Exp Med 2005 1.90
3 The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J Exp Med 2003 1.87
4 Anthrax toxins: a weapon to systematically dismantle the host immune defenses. Mol Aspects Med 2009 1.61
5 The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. J Biol Chem 2002 1.55
6 Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia. Blood 2010 1.43
7 The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells. J Leukoc Biol 2009 1.40
8 p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells. Mol Cell Biol 2004 1.38
9 T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions. Proc Natl Acad Sci U S A 2003 1.37
10 Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering. Biochem J 2003 1.35
11 Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases. FASEB J 2005 1.31
12 Intracellular mediators of CXCR4-dependent signaling in T cells. Immunol Lett 2007 1.19
13 Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling. Cell Microbiol 2006 1.15
14 F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts. Eur J Immunol 2002 1.14
15 p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells. Blood 2007 1.09
16 Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system. J Cell Sci 2014 1.05
17 Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival. Oncogene 2005 1.02
18 Nonsteroidal anti-inflammatory drugs suppress T-cell activation by inhibiting p38 MAPK induction. J Biol Chem 2001 1.02
19 The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling. PLoS Pathog 2009 1.00
20 T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck. Eur J Immunol 2003 0.99
21 Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis. Proc Natl Acad Sci U S A 2012 0.99
22 T lymphocytes as targets of statins: molecular mechanisms and therapeutic perspectives. Inflamm Allergy Drug Targets 2007 0.97
23 Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis. Infect Immun 2008 0.97
24 Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. Eur J Immunol 2006 0.92
25 SRC family kinases as potential therapeutic targets for malignancies and immunological disorders. Curr Med Chem 2008 0.92
26 The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse. J Exp Med 2011 0.92
27 Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells. Eur J Immunol 2006 0.92
28 Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus. J Leukoc Biol 2009 0.91
29 Intraflagellar transport: a new player at the immune synapse. Trends Immunol 2011 0.91
30 Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium. Immunol Rev 2013 0.90
31 S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis. Blood 2012 0.88
32 SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling. J Immunol 2011 0.88
33 Apoptosis and oxidative stress-related diseases: the p66Shc connection. Curr Mol Med 2009 0.87
34 The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of T(H)17 cell development. J Allergy Clin Immunol 2011 0.86
35 The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity. Blood 2008 0.86
36 Conditional up-regulation of IL-2 production by p38 MAPK inactivation is mediated by increased Erk1/2 activity. J Leukoc Biol 2006 0.86
37 p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells. J Cell Physiol 2007 0.86
38 Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters. Immunol Rev 2009 0.85
39 The glycerophosphoinositols: from lipid metabolites to modulators of T-cell signaling. Front Immunol 2013 0.84
40 Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects. Blood 2005 0.83
41 The thrombin peptide, TP508, enhances cytokine release and activates signaling events. Peptides 2004 0.83
42 Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling. Blood 2004 0.83
43 T-cell-based immunotherapy of autoimmune diseases. Expert Rev Vaccines 2013 0.82
44 Distinct spatial and temporal distribution of ZAP70 and Lck following stimulation of interferon and T-cell receptors. J Mol Biol 2005 0.81
45 Glycerophosphoinositol-4-phosphate enhances SDF-1alpha-stimulated T-cell chemotaxis through PTK-dependent activation of Vav. Cell Signal 2007 0.81
46 Regulation of vesicular traffic at the T cell immune synapse: lessons from the primary cilium. Traffic 2015 0.81
47 Normal B-1 cell development but defective BCR signaling in Lck-/- mice. Eur J Immunol 2003 0.81
48 Expression in T-cells of the proapoptotic protein p66SHC is controlled by promoter demethylation. Biochem Biophys Res Commun 2006 0.80
49 The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine production. Cell Microbiol 2007 0.79
50 Impaired TH2 response in patients with Vav1-deficient common variable immunodeficiency with T-cell defects. J Allergy Clin Immunol 2010 0.79
51 T cell targeting by anthrax toxins: two faces of the same coin. Toxins (Basel) 2011 0.78
52 Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation. J Immunol 2009 0.78
53 Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation. Eur J Immunol 2008 0.77
54 p66Shc-dependent apoptosis requires Lck and CamKII activity. Apoptosis 2012 0.77
55 p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics. J Leukoc Biol 2013 0.76
56 p66Shc is a negative regulator of FcεRI-dependent signaling in mast cells. J Immunol 2011 0.76
57 The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation. PLoS One 2011 0.76
58 Signaling at the immune synapse: vesicular trafficking takes the stage. Cell Mol Immunol 2013 0.75
59 Shigella targets T cells. Cell Host Microbe 2011 0.75
60 The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development. J Leukoc Biol 2013 0.75
61 DNA methylation and TLR9 ligands: not only a matter of semantics. Immunol Lett 2008 0.75
62 Negative regulation of immunoreceptor signaling by protein adapters: Shc proteins join the club. FEBS Lett 2010 0.75
63 Inhibition of ShcA isoforms p46/p52Shc enhances HIV-1 replication in CD4+ T-lymphocytes. J Cell Physiol 2004 0.75