Published in J Virol on January 11, 2012
Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome. Cell Host Microbe (2013) 1.97
Camouflage and misdirection: the full-on assault of ebola virus disease. Cell (2014) 1.07
The L-VP35 and L-L interaction domains reside in the amino terminus of the Ebola virus L protein and are potential targets for antivirals. Virology (2013) 0.89
The VP3 factor from viruses of Birnaviridae family suppresses RNA silencing by binding both long and small RNA duplexes. PLoS One (2012) 0.88
Innate immune evasion by filoviruses. Virology (2015) 0.82
Did silencing suppression counter-defensive strategy contribute to origin and evolution of the triple gene block coding for plant virus movement proteins? Front Plant Sci (2012) 0.80
HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs. RNA Biol (2015) 0.76
Acquisition of Full-Length Viral Helicase Domains by Insect Retrotransposon-Encoded Polypeptides. Front Microbiol (2015) 0.75
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
A species of small antisense RNA in posttranscriptional gene silencing in plants. Science (1999) 19.34
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17.64
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci U S A (2003) 8.73
P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction. Dev Cell (2003) 8.42
Gene silencing in mammals by small interfering RNAs. Nat Rev Genet (2002) 7.80
Sequence requirements for micro RNA processing and function in human cells. RNA (2003) 7.46
The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A (2000) 5.46
Induction and suppression of RNA silencing: insights from viral infections. Nat Rev Genet (2005) 4.98
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. J Virol (2003) 4.73
Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study. Lancet (2010) 4.52
Initiation and maintenance of virus-induced gene silencing Plant Cell (1998) 4.50
The diversity of RNA silencing pathways in plants. Trends Genet (2006) 4.32
Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems. J Virol (1999) 4.32
A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs. EMBO J (2002) 3.95
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc Natl Acad Sci U S A (2004) 3.85
Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J Virol (2006) 3.84
Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase. Pharmacol Ther (1998) 3.64
Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections. J Infect Dis (1999) 3.62
Silencing on the spot. Induction and suppression of RNA silencing in the Agrobacterium-mediated transient expression system. Plant Physiol (2001) 3.43
Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nat Med (2010) 3.25
Virus counterdefense: diverse strategies for evading the RNA-silencing immunity. Annu Rev Microbiol (2006) 3.15
Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors. EMBO J (2006) 3.00
The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein. Mol Cell (2002) 2.80
The Ebola virus VP35 protein is a suppressor of RNA silencing. PLoS Pathog (2007) 2.48
Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells. Hum Gene Ther (1998) 2.29
Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence. J Virol (2006) 2.14
Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J Virol (2009) 2.10
Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat Struct Mol Biol (2010) 2.01
The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR. J Virol (2006) 2.00
Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus. J Virol (2008) 1.96
The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants. J Gen Virol (2004) 1.93
Evasion of interferon responses by Ebola and Marburg viruses. J Interferon Cytokine Res (2009) 1.91
Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery. PLoS Pathog (2009) 1.78
Adenosine kinase inhibition and suppression of RNA silencing by geminivirus AL2 and L2 proteins. J Virol (2005) 1.76
Viral suppressors of RNA silencing. Trends Plant Sci (2011) 1.73
Structure of the Ebola VP35 interferon inhibitory domain. Proc Natl Acad Sci U S A (2009) 1.71
Ebola virus selectively inhibits responses to interferons, but not to interleukin-1beta, in endothelial cells. J Virol (1999) 1.68
Chimpanzee adenovirus vaccine protects against Zaire Ebola virus. Virology (2005) 1.63
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc Natl Acad Sci U S A (2009) 1.48
Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain. J Virol (2009) 1.46
Direct and indirect roles of viral suppressors of RNA silencing in pathogenesis. Annu Rev Phytopathol (2008) 1.40
HIV-1 Tat RNA silencing suppressor activity is conserved across kingdoms and counteracts translational repression of HIV-1. Proc Natl Acad Sci U S A (2009) 1.39
A call to arms: coevolution of animal viruses and host innate immune responses. Trends Genet (2007) 1.38
Molecular basis for PKR activation by PACT or dsRNA. Proc Natl Acad Sci U S A (2006) 1.28
Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway. J Virol (2011) 1.28
Human influenza virus NS1 protein enhances viral pathogenicity and acts as an RNA silencing suppressor in plants. J Gen Virol (2004) 1.26
Protection against lethal challenge by Ebola virus-like particles produced in insect cells. Virology (2008) 1.22
Enhanced protection against Ebola virus mediated by an improved adenovirus-based vaccine. PLoS One (2009) 1.16
RNA silencing directed against geminiviruses: post-transcriptional and epigenetic components. Biochim Biophys Acta (2010) 1.08
Anti-viral RNA silencing: do we look like plants? Retrovirology (2006) 1.03
Highly efficient regulation of gene expression by tetracycline in a replication-defective herpes simplex viral vector. Mol Ther (2006) 0.93
Ebola and Marburg viruses: pathogenesis and development of countermeasures. Curr Mol Med (2005) 0.93
Human viruses under attack by small inhibitory RNA. Trends Microbiol (2003) 0.91
Herpes simplex virus type 1 suppresses RNA-induced gene silencing in mammalian cells. J Virol (2009) 0.89
Adenosine kinase inhibition and suppression of RNA silencing by geminivirus AL2 and L2 proteins. J Virol (2005) 1.76
Viral genome methylation as an epigenetic defense against geminiviruses. J Virol (2008) 1.58
Geminivirus AL2 and L2 proteins interact with and inactivate SNF1 kinase. Plant Cell (2003) 1.47
Adenosine kinase is inactivated by geminivirus AL2 and L2 proteins. Plant Cell (2003) 1.43
Suppression of methylation-mediated transcriptional gene silencing by βC1-SAHH protein interaction during geminivirus-betasatellite infection. PLoS Pathog (2011) 1.30
Geminivirus AL2 and L2 proteins suppress transcriptional gene silencing and cause genome-wide reductions in cytosine methylation. J Virol (2009) 1.25
Identification of a minimal sequence required for activation of the tomato golden mosaic virus coat protein promoter in protoplasts. Virology (2003) 1.16
RNA silencing directed against geminiviruses: post-transcriptional and epigenetic components. Biochim Biophys Acta (2010) 1.08
Functional modulation of the geminivirus AL2 transcription factor and silencing suppressor by self-interaction. J Virol (2007) 1.07
Contribution of the 3'- to 5'-exonuclease activity of herpes simplex virus type 1 DNA polymerase to the fidelity of DNA synthesis. J Biol Chem (2004) 1.03
The herpes simplex virus type 1 DNA polymerase processivity factor increases fidelity without altering pre-steady-state rate constants for polymerization or excision. J Biol Chem (2003) 1.03
Arabidopsis double-stranded RNA binding protein DRB3 participates in methylation-mediated defense against geminiviruses. J Virol (2013) 1.00
Phylogenetic analysis and the evolution of the 18S rRNA gene typing system of Acanthamoeba. J Eukaryot Microbiol (2015) 0.97
Functional interaction between the herpes simplex virus type 1 polymerase processivity factor and origin-binding proteins: enhancement of UL9 helicase activity. J Virol (2003) 0.94
Evidence against a simple tethering model for enhancement of herpes simplex virus DNA polymerase processivity by accessory protein UL42. J Virol (2002) 0.93
Production of carboxylic acids from hydrolyzed corn meal by immobilized cell fermentation in a fibrous-bed bioreactor. Bioresour Technol (2002) 0.92
Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity. J Biol Chem (2007) 0.90
3' to 5' exonuclease activity of herpes simplex virus type 1 DNA polymerase modulates its strand displacement activity. J Virol (2003) 0.89
Herpes simplex virus type 1 suppresses RNA-induced gene silencing in mammalian cells. J Virol (2009) 0.89
Changes in subcellular localization reveal interactions between human cytomegalovirus terminase subunits. Virol J (2012) 0.88
Improved expression of recombinant GFP using a replicating vector based on Beet curly top virus in leaf-disks and infiltrated Nicotiana benthamiana leaves. Plant Mol Biol (2007) 0.87
Effects of the crinivirus coat protein-interacting plant protein SAHH on post-transcriptional RNA silencing and its suppression. Mol Plant Microbe Interact (2013) 0.84
C4 protein of Beet severe curly top virus is a pathomorphogenetic factor in Arabidopsis. Plant Cell Rep (2010) 0.84
Development of a gene silencing DNA vector derived from a broad host range geminivirus. Plant Methods (2009) 0.83
On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase. DNA Repair (Amst) (2004) 0.82
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites. DNA Repair (Amst) (2007) 0.82
Processing of lagging-strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase. J Virol (2010) 0.80
The herpes simplex virus type 1 DNA polymerase processivity factor, UL42, does not alter the catalytic activity of the UL9 origin-binding protein but facilitates its loading onto DNA. Nucleic Acids Res (2005) 0.79
Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98. J Gen Virol (2011) 0.79
Identification of a promoter motif involved in Curtovirus sense-gene expression in transgenic Arabidopsis. Mol Cells (2008) 0.77
Isolation, morphologic, serologic and molecular identification of Acanthamoeba T4 genotype from the liver of a Temminck's tragopan (Tragopan temminckii). Vet Parasitol (2010) 0.77
Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymerase. J Nucleic Acids (2010) 0.75
Expression of recombinant endostatin in Agrobacterium-inoculated leaf disks of Nicotiana tabacum var. Xanthi. Biotechnol Lett (2004) 0.75