Remission in early rheumatoid arthritis: predicting treatment response.

Clinical response within 12 weeks as a predictor of future low disease activity in patients with early RA: results from the TEAR Trial. J Rheumatol (2013) 0.96

Early remission is associated with improved survival in patients with inflammatory polyarthritis: results from the Norfolk Arthritis Register. Ann Rheum Dis (2013) 0.88

Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: patient global health is a confounder. Arthritis Res Ther (2013) 0.85

Window of opportunity to achieve major outcomes in early rheumatoid arthritis patients: how persistence with therapy matters. Arthritis Res Ther (2015) 0.83

ACPA-positive and ACPA-negative rheumatoid arthritis differ in their requirements for combination DMARDs and corticosteroids: secondary analysis of a randomized controlled trial. Arthritis Res Ther (2014) 0.82

Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? BMC Med (2013) 0.82

Molecular characterization of rheumatoid arthritis with magnetic resonance imaging. Top Magn Reson Imaging (2011) 0.79

Rheumatoid factor positivity is associated with increased joint destruction and upregulation of matrix metalloproteinase 9 and cathepsin k gene expression in the peripheral blood in rheumatoid arthritic patients treated with methotrexate. Int J Rheumatol (2013) 0.79

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med (2013) 11.93

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis (2013) 10.92

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis (2010) 10.03

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature (2005) 7.72

An SCN9A channelopathy causes congenital inability to experience pain. Nature (2006) 7.01

A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature (2009) 5.65

Influenza A viruses of migrating wild aquatic birds in North America. Vector Borne Zoonotic Dis (2004) 4.89

Clozapine alone versus clozapine and risperidone with refractory schizophrenia. N Engl J Med (2006) 4.16

A randomized placebo-controlled trial of methotrexate in psoriatic arthritis. Rheumatology (Oxford) (2012) 3.56

Lateral gene transfer and the origins of prokaryotic groups. Annu Rev Genet (2003) 3.50

Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell (2012) 3.30

The influenza virus gene pool in a poultry market in South central china. Virology (2003) 3.25

Characterization of H5N1 influenza viruses that continue to circulate in geese in southeastern China. J Virol (2002) 2.97

Influenza in migratory birds and evidence of limited intercontinental virus exchange. PLoS Pathog (2007) 2.94

119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10-12 October 2003, Naarden, The Netherlands. Neuromuscul Disord (2004) 2.85

Interstitial lung disease has a poor prognosis in rheumatoid arthritis: results from an inception cohort. Rheumatology (Oxford) (2010) 2.67

Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase. AIDS (2010) 2.57

Troponin T as a predictive marker of morbidity in patients with fractured neck of femur. Injury (2008) 2.30

Distinct psychological distress trajectories in rheumatoid arthritis: findings from an inception cohort. J Psychosom Res (2011) 2.20

Presentation of childhood CNS tumours: a systematic review and meta-analysis. Lancet Oncol (2007) 2.18

The diagnosis and prognosis of early arthritis: rationale for new prognostic criteria. Arthritis Rheum (2002) 2.15

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus. J Neurosci (2006) 2.01

The effects of violent video game habits on adolescent hostility, aggressive behaviors, and school performance. J Adolesc (2004) 1.97

Mutant KRAS codon 12 and 13 alleles in patients with metastatic colorectal cancer: assessment as prognostic and predictive biomarkers of response to panitumumab. J Clin Oncol (2012) 1.97

Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol (2008) 1.94

Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity. Mol Pharmacol (2010) 1.93

Climate change effects on plague and tularemia in the United States. Vector Borne Zoonotic Dis (2007) 1.92

Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology (2002) 1.91

Fibromyalgia syndrome module at OMERACT 9: domain construct. J Rheumatol (2009) 1.87

An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nat Chem Biol (2007) 1.83

Physical function and health related quality of life: analysis of 2-year data from randomized, controlled studies of leflunomide, sulfasalazine, or methotrexate in patients with active rheumatoid arthritis. J Rheumatol (2005) 1.81

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology (2009) 1.80

A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning. Mol Pharmacol (2009) 1.76

Opportunistic and systematic screening for chlamydia: a study of consultations by young adults in general practice. Br J Gen Pract (2006) 1.75

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts. Arthritis Rheum (2009) 1.75

Investigating Black-White differences in prostate cancer prognosis: A systematic review and meta-analysis. Int J Cancer (2008) 1.73

Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis. Ann Rheum Dis (2007) 1.73

Combined influence of physical activity and screen time recommendations on childhood overweight. J Pediatr (2008) 1.70

Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity. Mol Pharmacol (2008) 1.68

Predicted exposures to steroid estrogens in U.K. rivers correlate with widespread sexual disruption in wild fish populations. Environ Health Perspect (2006) 1.67

Rickettsia sibirica isolation from a patient and detection in ticks, Portugal. Emerg Infect Dis (2006) 1.63

Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nat Rev Rheumatol (2012) 1.62

The risk of prostate cancer amongst black men in the United Kingdom: the PROCESS cohort study. Eur Urol (2007) 1.62

Illness beliefs predict disability in rheumatoid arthritis. J Psychosom Res (2009) 1.62

Identifying core domains to assess flare in rheumatoid arthritis: an OMERACT international patient and provider combined Delphi consensus. Ann Rheum Dis (2012) 1.62

Statistical modeling suggests that antiandrogens in effluents from wastewater treatment works contribute to widespread sexual disruption in fish living in English rivers. Environ Health Perspect (2009) 1.61

Microbial community dynamics in a seasonally anoxic fjord: Saanich Inlet, British Columbia. Environ Microbiol (2009) 1.60

Annual Report of the Chief Medical Officer: infection and the rise of antimicrobial resistance. Lancet (2013) 1.56

Remission in early rheumatoid arthritis. J Rheumatol (2010) 1.55

Economic aspects of treatment options in rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis (2010) 1.54

The risk of prostate cancer amongst South Asian men in southern England: the PROCESS cohort study. BJU Int (2008) 1.53

Television and video game exposure and the development of attention problems. Pediatrics (2010) 1.53

Effect of the early use of the anti-tumor necrosis factor adalimumab on the prevention of job loss in patients with early rheumatoid arthritis. Arthritis Rheum (2008) 1.52

Identification of a specific isoform of tomato lipoxygenase (TomloxC) involved in the generation of fatty acid-derived flavor compounds. Plant Physiol (2004) 1.51

First-line DMARD choice in early rheumatoid arthritis--do prognostic factors play a role? Rheumatology (Oxford) (2009) 1.49

Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study). Am J Cardiol (2009) 1.45

Impact of locoregional therapy and alpha-fetoprotein on outcomes in transplantation for liver cancer: a UNOS Region 6 pooled analysis. Clin Transplant (2012) 1.44

Foot pain in rheumatoid arthritis prevalence, risk factors and management: an epidemiological study. Clin Rheumatol (2009) 1.42

The role of outcome measures in assessing change in the at-risk rheumatoid foot. J Tissue Viability (2004) 1.40

Cost-effectiveness of combination nonbiologic disease-modifying antirheumatic drug strategies in patients with early rheumatoid arthritis. J Rheumatol (2011) 1.40

Prescribed exercise in people with fibromyalgia: parallel group randomised controlled trial. BMJ (2002) 1.37

Clinical application of SPHARM-PDM to quantify temporomandibular joint osteoarthritis. Comput Med Imaging Graph (2010) 1.36

Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade. Arthritis Rheum (2007) 1.34

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions. Ann Rheum Dis (2012) 1.33

Evaluation of a multiple ecological level child obesity prevention program: Switch what you Do, View, and Chew. BMC Med (2009) 1.33

Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice. J Neurosci (2012) 1.33

Influenza A viruses in feral Canadian ducks: extensive reassortment in nature. J Gen Virol (2004) 1.32

Live bird markets of Bangladesh: H9N2 viruses and the near absence of highly pathogenic H5N1 influenza. PLoS One (2011) 1.32

The biological basis of injury and neuroprotection in the fetal and neonatal brain. Int J Dev Neurosci (2011) 1.31

Osteochondral alterations in osteoarthritis. Bone (2011) 1.31

Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis. Arthritis Rheum (2011) 1.31

Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. ChemMedChem (2009) 1.29

DNA extraction from 0.22 microM Sterivex filters and cesium chloride density gradient centrifugation. J Vis Exp (2009) 1.28

Unmet supportive care needs and interest in services among patients with a brain tumour and their carers. Patient Educ Couns (2008) 1.28

Interstitial vascularity in fibrosing alveolitis. Am J Respir Crit Care Med (2002) 1.27

Validity of the work productivity and activity impairment questionnaire--general health version in patients with rheumatoid arthritis. Arthritis Res Ther (2010) 1.26

Modeling the progression of rheumatoid arthritis: a two-country model to estimate costs and consequences of rheumatoid arthritis. Arthritis Rheum (2002) 1.26

Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on antiretroviral therapy (ART) in sub-Saharan Africa: frequency and clinical significance. AIDS Res Ther (2008) 1.22

Huntingtin associates with acidic phospholipids at the plasma membrane. J Biol Chem (2005) 1.22

Intron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS. J Neurosci (2008) 1.22

Fibromyalgic rheumatoid arthritis and disease assessment. Rheumatology (Oxford) (2010) 1.21

Using a Delphi process to develop an effective train-the-trainers program to train health and social care professionals throughout Europe. J Trauma Stress (2012) 1.21

High rate of loss to clinical follow up among African HIV-infected patients attending a London clinic: a retrospective analysis of a clinical cohort. J Int AIDS Soc (2010) 1.21

Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors. Arthritis Rheum (2010) 1.21

State of knowledge and concerns on cyanobacterial blooms and cyanotoxins. Environ Int (2013) 1.19

Influenza a virus migration and persistence in North American wild birds. PLoS Pathog (2013) 1.19

Antigenic and molecular characterization of avian influenza A(H9N2) viruses, Bangladesh. Emerg Infect Dis (2013) 1.19

Co-morbidities in established rheumatoid arthritis. Best Pract Res Clin Rheumatol (2011) 1.19

Quality of life among patients with a brain tumor and their carers. J Psychosom Res (2007) 1.18

HIV care and the incidence of acute renal failure. Clin Infect Dis (2008) 1.18

The presence of eschars, but not greater severity, in Portuguese patients infected with Israeli spotted fever. Ann N Y Acad Sci (2005) 1.18

Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway. Ann Rheum Dis (2012) 1.17

Puzzling inefficiency of H5N1 influenza vaccines in Egyptian poultry. Proc Natl Acad Sci U S A (2010) 1.17

The relationship between social deprivation, disease outcome measures, and response to treatment in patients with stable, long-standing rheumatoid arthritis. J Rheumatol (2005) 1.16