Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
2
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
3
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
4
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
5
|
Genome-wide association analysis identifies 20 loci that influence adult height.
|
Nat Genet
|
2008
|
16.92
|
6
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
7
|
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
Nat Genet
|
2011
|
13.25
|
8
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
9
|
Genome-wide association study identifies eight loci associated with blood pressure.
|
Nat Genet
|
2009
|
12.44
|
10
|
Prepublication data sharing.
|
Nature
|
2009
|
12.24
|
11
|
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
Nat Genet
|
2009
|
12.19
|
12
|
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
|
Lancet
|
2012
|
12.10
|
13
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
14
|
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
|
Nat Genet
|
2010
|
8.55
|
15
|
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
|
Science
|
2012
|
7.94
|
16
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
17
|
LDL-cholesterol concentrations: a genome-wide association study.
|
Lancet
|
2008
|
6.44
|
18
|
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
|
Nat Genet
|
2009
|
6.31
|
19
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
20
|
The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome.
|
BMC Cardiovasc Disord
|
2008
|
5.33
|
21
|
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.
|
JAMA
|
2009
|
5.32
|
22
|
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
|
PLoS Genet
|
2009
|
4.97
|
23
|
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.
|
Am J Hum Genet
|
2008
|
4.79
|
24
|
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
|
Am J Hum Genet
|
2008
|
4.69
|
25
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
26
|
Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
|
Arterioscler Thromb Vasc Biol
|
2010
|
4.08
|
27
|
Genetic loci influencing kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
3.75
|
28
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
29
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
30
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
31
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
32
|
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
Nat Genet
|
2011
|
3.18
|
33
|
Genetic variation in LIN28B is associated with the timing of puberty.
|
Nat Genet
|
2009
|
3.09
|
34
|
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
|
Nat Genet
|
2011
|
2.73
|
35
|
CUBN is a gene locus for albuminuria.
|
J Am Soc Nephrol
|
2011
|
2.70
|
36
|
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus.
|
Nature
|
2011
|
2.59
|
37
|
Use of genome-wide association studies for drug repositioning.
|
Nat Biotechnol
|
2012
|
2.51
|
38
|
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|
Nat Genet
|
2012
|
2.12
|
39
|
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.
|
PLoS Genet
|
2009
|
2.09
|
40
|
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
|
Proc Natl Acad Sci U S A
|
2011
|
2.01
|
41
|
Male-pattern baldness susceptibility locus at 20p11.
|
Nat Genet
|
2008
|
1.87
|
42
|
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.
|
Atherosclerosis
|
2009
|
1.78
|
43
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
44
|
A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study.
|
Am J Hum Genet
|
2004
|
1.71
|
45
|
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
|
Nat Genet
|
2010
|
1.67
|
46
|
Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index.
|
Int J Epidemiol
|
2011
|
1.61
|
47
|
High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study.
|
Ann Intern Med
|
2002
|
1.58
|
48
|
Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study.
|
Atherosclerosis
|
2007
|
1.36
|
49
|
Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).
|
Am J Cardiol
|
2005
|
1.32
|
50
|
Dose-dependent positive association between cigarette smoking, abdominal obesity and body fat: cross-sectional data from a population-based survey.
|
BMC Public Health
|
2011
|
1.32
|
51
|
The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors.
|
BMC Psychiatry
|
2009
|
1.29
|
52
|
Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study.
|
Am Heart J
|
2003
|
1.28
|
53
|
Metagenomics: the role of the microbiome in cardiovascular diseases.
|
Curr Opin Lipidol
|
2006
|
1.25
|
54
|
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.
|
PLoS Genet
|
2010
|
1.25
|
55
|
Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array.
|
Hypertension
|
2010
|
1.22
|
56
|
Prevalence, awareness, treatment and control of high blood pressure in a Swiss city general population: the CoLaus study.
|
Eur J Cardiovasc Prev Rehabil
|
2009
|
1.22
|
57
|
Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
|
PLoS Genet
|
2009
|
1.18
|
58
|
Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.
|
PLoS Genet
|
2012
|
1.14
|
59
|
Alcohol drinking and cardiovascular risk in a population with high mean alcohol consumption.
|
Am J Cardiol
|
2008
|
1.12
|
60
|
A genome-wide association study of neuroticism in a population-based sample.
|
PLoS One
|
2010
|
1.09
|
61
|
Nutrigenomics and nutrigenetics.
|
Curr Opin Lipidol
|
2004
|
1.09
|
62
|
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
|
Am J Clin Nutr
|
2013
|
1.08
|
63
|
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins.
|
Hum Mol Genet
|
2009
|
1.08
|
64
|
Insulin-secreting beta-cell dysfunction induced by human lipoproteins.
|
J Biol Chem
|
2003
|
1.08
|
65
|
Prevalence of obesity and abdominal obesity in the Lausanne population.
|
BMC Public Health
|
2008
|
1.05
|
66
|
Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes.
|
Neurobiol Aging
|
2008
|
1.03
|
67
|
Methods for testing association between uncertain genotypes and quantitative traits.
|
Biostatistics
|
2010
|
1.02
|
68
|
Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation.
|
Diabetes
|
2012
|
1.00
|
69
|
Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia.
|
J Lipid Res
|
2005
|
1.00
|
70
|
Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.
|
PLoS One
|
2011
|
0.99
|
71
|
Association between C-reactive protein and adiposity in women.
|
J Clin Endocrinol Metab
|
2009
|
0.98
|
72
|
Genetic and functional association of FAM5C with myocardial infarction.
|
BMC Med Genet
|
2008
|
0.96
|
73
|
Effects of particulate matter on inflammatory markers in the general adult population.
|
Part Fibre Toxicol
|
2012
|
0.94
|
74
|
Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study.
|
PLoS One
|
2011
|
0.92
|
75
|
Contribution of major cardiovascular risk factors to familial premature coronary artery disease: the GENECARD project.
|
J Am Coll Cardiol
|
2002
|
0.92
|
76
|
Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland.
|
Eur J Cardiovasc Prev Rehabil
|
2008
|
0.91
|
77
|
Distribution of plasma levels of adiponectin and leptin in an adult Caucasian population.
|
Clin Endocrinol (Oxf)
|
2009
|
0.91
|
78
|
Not all inflammatory markers are linked to kidney function: results from a population-based study.
|
Am J Nephrol
|
2012
|
0.91
|
79
|
Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study.
|
BMC Public Health
|
2011
|
0.90
|
80
|
Hyperlipidemia in HIV-infected children treated with protease inhibitors: relevance for cardiovascular diseases.
|
J Acquir Immune Defic Syndr
|
2002
|
0.89
|
81
|
Prevalence, treatment and control of dyslipidaemia in Switzerland: still a long way to go.
|
Eur J Cardiovasc Prev Rehabil
|
2010
|
0.88
|
82
|
Predictive accuracy of original and recalibrated Framingham risk score in the Swiss population.
|
Int J Cardiol
|
2008
|
0.88
|
83
|
Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.
|
Hum Mol Genet
|
2011
|
0.87
|
84
|
Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort.
|
BMC Genomics
|
2012
|
0.86
|
85
|
Prevalence of normal weight obesity in Switzerland: effect of various definitions.
|
Eur J Nutr
|
2008
|
0.85
|
86
|
Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology.
|
J Invest Dermatol
|
2013
|
0.85
|
87
|
Patients' sibling history was sensitive for hypertension and specific for diabetes.
|
J Clin Epidemiol
|
2004
|
0.84
|
88
|
Genetic deficiency of plasma lipoprotein-associated phospholipase A2 (PLA2G7 V297F null mutation) and risk of Alzheimer's disease in Japan.
|
J Alzheimers Dis
|
2010
|
0.83
|
89
|
Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia.
|
J Clin Endocrinol Metab
|
2007
|
0.83
|
90
|
The APOE locus and the pharmacogenetics of lipid response.
|
Curr Opin Lipidol
|
2002
|
0.83
|
91
|
Surrogate markers for atherosclerosis in overweight subjects with atherogenic dyslipidemia: the GEMS project.
|
Angiology
|
2008
|
0.82
|
92
|
Serum calcium levels are associated with novel cardiometabolic risk factors in the population-based CoLaus study.
|
PLoS One
|
2011
|
0.82
|
93
|
FGF21 signalling pathway and metabolic traits - genetic association analysis.
|
Eur J Hum Genet
|
2010
|
0.81
|
94
|
Truncated robust distance for clinical laboratory safety data monitoring and assessment.
|
J Biopharm Stat
|
2012
|
0.80
|
95
|
Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes.
|
Pharmacogenet Genomics
|
2008
|
0.80
|
96
|
High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease--the GENECARD project.
|
Atherosclerosis
|
2006
|
0.79
|
97
|
Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells.
|
Mol Endocrinol
|
2009
|
0.79
|
98
|
Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension.
|
Hum Mol Genet
|
2012
|
0.79
|
99
|
Association of ABCB1 genetic variants with renal function in Africans and in Caucasians.
|
BMC Med Genomics
|
2008
|
0.78
|
100
|
Short-term administration of isotretinoin elevates plasma triglyceride concentrations without affecting insulin sensitivity in healthy humans.
|
Metabolism
|
2004
|
0.78
|
101
|
Efficacy and safety of fluvastatin in hyperlipidemic protease inhibitor-treated HIV-infected patients.
|
AIDS
|
2002
|
0.78
|
102
|
Reply to Rational drug repositioning by medical genetics.
|
Nat Biotechnol
|
2013
|
0.78
|
103
|
A genomewide association study of smoking relapse in four European population-based samples.
|
Psychiatr Genet
|
2013
|
0.77
|
104
|
Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.
|
Front Genet
|
2011
|
0.75
|
105
|
Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.
|
Int J Mol Epidemiol Genet
|
2011
|
0.75
|
106
|
European lipoprotein club: report of the 25th ELC annual conference. Tutzing, 9-12 September 2002.
|
Atherosclerosis
|
2003
|
0.75
|
107
|
Use of constant denaturant capillary electrophoresis of pooled blood samples to identify single-nucleotide polymorphisms in the genes (Scnn1a and Scnn1b) encoding the alpha and beta subunits of the epithelial sodium channel.
|
Clin Chem
|
2002
|
0.75
|
108
|
'Omic' approaches and lipid metabolism: are these new technologies holding their promises?
|
Curr Opin Lipidol
|
2003
|
0.75
|
109
|
Glucose-induced insulin secretion in dyslipidemic and normolipidemic patients with normal glucose tolerance.
|
Diabetes Care
|
2005
|
0.75
|
110
|
Cardiovascular risk estimation and eligibility for statins in primary prevention comparing different strategies.
|
Am J Cardiol
|
2009
|
0.75
|
111
|
Smoking offsets the metabolic benefits of parental longevity in women: the CoLaus study.
|
Prev Med
|
2008
|
0.75
|
112
|
Genes, lipids and aging: is it all accounted for by cardiovascular disease risk?: editorial review.
|
Curr Opin Lipidol
|
2005
|
0.75
|
113
|
[Dyslipidemias and cardiovascular diseases: towards a new perspective].
|
Rev Med Suisse Romande
|
2002
|
0.75
|
114
|
[Dyslipidemia and metabolic syndrome].
|
Rev Med Suisse Romande
|
2002
|
0.75
|
115
|
Prevalence and characteristics of homeopathy users in a representative sample of the Lausanne population: CoLaus study.
|
Pharmacoepidemiol Drug Saf
|
2008
|
0.75
|
116
|
LDLs induce fibroblast spreading independently of the LDL receptor via activation of the p38 MAPK pathway.
|
J Lipid Res
|
2003
|
0.75
|