Published in Biochem J on April 15, 2012
The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape. Sci Signal (2013) 0.94
Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53. Cell Death Differ (2015) 0.88
The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors. Front Mol Biosci (2015) 0.82
Pontin is a critical regulator for AML1-ETO-induced leukemia. Leukemia (2013) 0.80
Discovery of new membrane-associated proteins overexpressed in small-cell lung cancer. J Thorac Oncol (2014) 0.80
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Nat Commun (2015) 0.80
ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy. Adv Cancer Res (2014) 0.80
Substrate recognition and function of the R2TP complex in response to cellular stress. Front Genet (2015) 0.79
Reptin and Pontin oligomerization and activity are modulated through histone H3 N-terminal tail interaction. J Biol Chem (2014) 0.78
Molecular determinants of the human α2C-adrenergic receptor temperature-sensitive intracellular traffic. Mol Pharmacol (2015) 0.78
Chromosome Missegregation Associated with RUVBL1 Deficiency. PLoS One (2015) 0.76
Vinardo: A Scoring Function Based on Autodock Vina Improves Scoring, Docking, and Virtual Screening. PLoS One (2016) 0.75
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS Med (2007) 2.39
Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo. PLoS Biol (2007) 2.28
In vivo MR imaging of intravascularly injected magnetically labeled mesenchymal stem cells in rat kidney and liver. Radiology (2004) 2.22
Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. PLoS Biol (2009) 2.15
HIV-1 integrase crosslinked oligomers are active in vitro. Nucleic Acids Res (2005) 1.96
In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence. J Hepatol (2010) 1.71
Synthesis and biological activity of phosphonate analogues and geometric isomers of the highly potent phosphoantigen (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate. J Med Chem (2008) 1.52
Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis. Am J Pathol (2006) 1.36
Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice. J Hepatol (2005) 1.29
Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration. Life Sci (2003) 1.29
Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts. Lab Invest (2002) 1.23
Replication of mitochondrial DNA occurs throughout the mitochondria of cultured human cells. Exp Cell Res (2003) 1.19
The multifaceted proteins Reptin and Pontin as major players in cancer. Biochim Biophys Acta (2010) 1.19
Mitochondria: from bioenergetics to the metabolic regulation of carcinogenesis. Front Biosci (Landmark Ed) (2009) 1.16
Pontin and reptin, two related ATPases with multiple roles in cancer. Cancer Res (2008) 1.15
Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS Biol (2010) 1.15
Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C. Proteomics (2005) 1.14
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients. Cell Div (2007) 1.13
Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. Int J Cancer (2009) 1.12
Nuclear entry of hepatitis B virus capsids involves disintegration to protein dimers followed by nuclear reassociation to capsids. PLoS Pathog (2009) 1.10
Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma. Hepatology (2007) 1.08
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. Free Radic Biol Med (2004) 1.08
Inhibition of rat liver fibrogenesis through noradrenergic antagonism. Hepatology (2002) 1.06
Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion. Lab Invest (2004) 1.05
3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase. J Chem Biol (2009) 1.05
Cellular retinol-binding protein-1 expression in normal and fibrotic/cirrhotic human liver: different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations. J Hepatol (2004) 1.03
Spiroplasma citri Spiralin Acts In Vitro as a Lectin Binding to Glycoproteins from Its Insect Vector Circulifer haematoceps. Phytopathology (2005) 1.02
Physiological type I collagen organization induces the formation of a novel class of linear invadosomes. Mol Biol Cell (2011) 1.01
Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis. Am J Physiol Gastrointest Liver Physiol (2007) 1.01
Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism. Hepatology (2009) 1.00
Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death. Mol Cancer Ther (2012) 1.00
Regulation of 3-phosphoinositide-dependent protein kinase 1 activity by homodimerization in live cells. Sci Signal (2010) 0.99
H(2)O(2), which causes macrophage-related stress, triggers induction of expression of virulence-associated plasmid determinants in Rhodococcus equi. Infect Immun (2002) 0.98
Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. Life Sci (2003) 0.97
Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model. Nucleic Acids Res (2011) 0.97
Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR-TAR* and TAR-aptamer. Nucleic Acids Res (2003) 0.97
Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology (2012) 0.97
Hepatocellular adenoma subtypes: the impact of overweight and obesity. Liver Int (2012) 0.96
Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis. Wound Repair Regen (2004) 0.95
Plasma membrane localization of Solanum tuberosum remorin from group 1, homolog 3 is mediated by conformational changes in a novel C-terminal anchor and required for the restriction of potato virus X movement]. Plant Physiol (2012) 0.95
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. J Hepatol (2006) 0.94
A charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis. FASEB J (2010) 0.93
PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol. Int J Biochem Cell Biol (2002) 0.93
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells. Int J Cancer (2003) 0.92
Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells. Int J Cancer (2002) 0.92
Cytokines pattern after surgical radiofrequency ablation of liver colorectal metastases. Gastroenterol Clin Biol (2007) 0.91
NMR and molecular modeling of wine tannins binding to saliva proteins: revisiting astringency from molecular and colloidal prospects. FASEB J (2010) 0.89
Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1. Blood (2012) 0.89
Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices. Lab Invest (2006) 0.89
The Agaricus bisporus cox1 gene: the longest mitochondrial gene and the largest reservoir of mitochondrial group i introns. PLoS One (2010) 0.89
Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism. J Biol Chem (2003) 0.89
The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinoma. Mol Cancer Res (2012) 0.88
Expression and activity of the cytolethal distending toxin of Helicobacter hepaticus. Biochem Biophys Res Commun (2004) 0.88
Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. Biochimie (2009) 0.88
Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells. Biol Cell (2012) 0.87
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. Neoplasia (2006) 0.87
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα. Cancer Res (2013) 0.87
Abnormal hepatic expression of fibrillin-1 in children with cholestasis. Am J Surg Pathol (2002) 0.87
Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance. Mol Cell Biol (2014) 0.87
Thrombin inhibits migration of human hepatic myofibroblasts. Am J Physiol Gastrointest Liver Physiol (2007) 0.85
Purification and characterization of an endo-exonuclease from Podospora anserina mitochondria. Biochim Biophys Acta (2002) 0.85
Hydrogen/deuterium exchange on yeast ATPase supramolecular protein complex analyzed at high sensitivity by MALDI mass spectrometry. J Am Soc Mass Spectrom (2003) 0.85
Expression of protease-activated receptors and tissue factor in human liver. Virchows Arch (2005) 0.85
Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic trioxide on CYP1A1 induction by polycyclic aromatic hydrocarbons. J Pharmacol Exp Ther (2003) 0.85
Innervation of the sinusoidal wall: regulation of the sinusoidal diameter. Anat Rec A Discov Mol Cell Evol Biol (2004) 0.85
Screening for toxic amyloid in yeast exemplifies the role of alternative pathway responsible for cytotoxicity. PLoS One (2009) 0.84
Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 Å resolution. Angew Chem Int Ed Engl (2013) 0.84
A protective role for CD154 in hepatic steatosis in mice. Hepatology (2010) 0.83
The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts. Int J Biochem Cell Biol (2005) 0.83
Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition. J Am Chem Soc (2008) 0.83
Absence of accessory subunit in the DNA polymerase gamma purified from yeast mitochondria. Mitochondrion (2004) 0.83
The elongation factor 1A: a novel regulator in the DNA replication/repair protein network in wheat cells? Plant Physiol Biochem (2007) 0.83
The ARE-associated factor AUF1 binds poly(A) in vitro in competition with PABP. Biochem J (2006) 0.82
Comparison of IMAC and MOAC for phosphopeptide enrichment by column chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.82
Base composition at mtDNA boundaries suggests a DNA triple helix model for human mitochondrial DNA large-scale rearrangements. Mol Genet Metab (2002) 0.82
Expression of tissue factor pathway inhibitor-2 in murine and human liver regulation during inflammation. Thromb Haemost (2004) 0.82
The colloidal state of tannins impacts the nature of their interaction with proteins: the case of salivary proline-rich protein/procyanidins binding. Langmuir (2012) 0.81
AlphaScreen-based characterization of the bifunctional kinase/RNase IRE1alpha: a novel and atypical drug target. J Biomol Screen (2010) 0.81
Chemical details on nucleolipid supramolecular architecture: molecular modeling and physicochemical studies. Langmuir (2012) 0.81
Complexomics study of two Helicobacter pylori strains of two pathological origins: potential targets for vaccine development and new insight in bacteria metabolism. Mol Cell Proteomics (2010) 0.81
Solution structure of quinoline- and pyridine-derived oligoamide foldamers. Chemistry (2005) 0.81
Three-dimensional structure and dynamics of wine tannin-saliva protein complexes. A multitechnique approach. Biochemistry (2003) 0.81
MD studies of the DIS/DIS kissing complex solution and x-ray structures. Oligonucleotides (2003) 0.80
Role of apoptosis in the remodeling of cholestatic liver injury following release of the mechanical stress. Virchows Arch (2003) 0.80
Engineering a G protein-coupled receptor for structural studies: stabilization of the BLT1 receptor ground state. Protein Sci (2009) 0.79
Structural and conformational analysis of two native procyanidin trimers. Magn Reson Chem (2007) 0.79
Expression of leukemia inhibitory factor (LIF) and its receptor gp190 in human liver and in cultured human liver myofibroblasts. Cloning of new isoforms of LIF mRNA. Comp Hepatol (2004) 0.79
Closing the gap on drug-induced liver injury. Hepatology (2012) 0.79
Reversible transition between alpha-helix and beta-sheet conformation of a transmembrane domain. Biochim Biophys Acta (2009) 0.79
Identification and biochemical analysis of a mitochondrial endonuclease of Podospora anserina related to curved-DNA binding proteins. Biochim Biophys Acta (2006) 0.79
Self-organisation of an oligodeoxynucleotide containing the G- and C-rich stretches of the direct repeats of the human mitochondrial DNA. Biochimie (2005) 0.79
A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid. Biochem J (2012) 0.78
A red wine polyphenolic extract reduces the activation phenotype of cultured human liver myofibroblasts. World J Gastroenterol (2008) 0.78