Published in IARC Sci Publ on January 01, 1990
A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res (1988) 17.88
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. Mutagenesis (2003) 2.29
DNA sequence analysis of revertants of the hisD3052 allele of Salmonella typhimurium TA98 using the polymerase chain reaction and direct sequencing: application to 1-nitropyrene-induced revertants. Mutat Res (1991) 1.94
Assessment of the reproductive toxicity of a complex mixture of 25 groundwater contaminants in mice and rats. Fundam Appl Toxicol (1995) 1.58
Collagen in tendon, ligament, and bone healing. A current review. Clin Orthop Relat Res (1995) 1.50
The DeltauvrB mutations in the Ames strains of Salmonella span 15 to 119 genes. Mutat Res (2001) 1.37
Primary immunolocalization of estrogen and progesterone target cells in the human anterior cruciate ligament. J Orthop Res (1996) 1.37
Toxicological interactions among arsenic, cadmium, chromium, and lead in human keratinocytes. Toxicol Sci (2001) 1.35
Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice. Environ Health Perspect (1989) 1.34
Effects of different exercise modes on mineralization, structure, and biomechanical properties of growing bone. J Appl Physiol (1985) (2003) 1.25
Comparative cytogenetic analysis of bone marrow damage induced in male B6C3F1 mice by multiple exposures to gaseous 1,3-butadiene. Environ Mutagen (1987) 1.24
In vivo rodent erythrocyte micronucleus assay. Mutat Res (1994) 1.22
Hotspot sites for acridine-induced frameshift mutations in bacteriophage T4 correspond to sites of action of the T4 type II topoisomerase. J Mol Biol (1988) 1.20
Guidelines for the conduct of micronucleus assays in mammalian bone marrow erythrocytes. Mutat Res (1987) 1.20
High incidence rate of hip fracture in Taiwan: estimated from a nationwide health insurance database. Osteoporos Int (2004) 1.18
Results of in vitro and in vivo genetic toxicity tests on methyl isocyanate. Environ Health Perspect (1987) 1.16
Excessive cycling converts PCR products to random-length higher molecular weight fragments. Nucleic Acids Res (1991) 1.14
Expandable endoprosthesis reconstruction in skeletally immature patients with tumors. Clin Orthop Relat Res (2000) 1.14
Mechanism and optimization of pH sensing using SnO2 nanobelt field effect transistors. Nano Lett (2008) 1.11
DNA damage and repair with age in individual human lymphocytes. Mutat Res (1990) 1.09
Abundant alkali-sensitive sites in DNA of human and mouse sperm. Exp Cell Res (1989) 1.08
Toxicology studies of a chemical mixture of 25 groundwater contaminants. III. Male reproduction study in B6C3F1 mice. Fundam Appl Toxicol (1989) 1.08
Hypoglycemic effect of guava juice in mice and human subjects. Am J Chin Med (1983) 1.05
A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides. Mutat Res (1991) 1.03
Microscopic laminotomies for degenerative lumbar spinal stenosis. J Spinal Disord (1998) 1.02
Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect. Mutat Res (2005) 1.01
Induction of genetic damage in human lymphocytes and mutations in Salmonella by trihalomethanes: role of red blood cells and GSTT1-1 polymorphism. Mutagenesis (1999) 1.01
Exploration of an interaction threshold for the joint toxicity of trichloroethylene and 1,1-dichloroethylene: utilization of a PBPK model. Arch Toxicol (1996) 1.01
Genotoxicity of tobacco smoke and tobacco smoke condensate. Mutat Res (1983) 1.00
Cytogenetic effects of inhaled benzene in murine bone marrow: induction of sister chromatid exchanges, chromosomal aberrations, and cellular proliferation inhibition in DBA/2 mice. Proc Natl Acad Sci U S A (1980) 1.00
In vivo analysis of cellular replication. Proc Natl Acad Sci U S A (1977) 1.00
Pharmacokinetics and metabolism of hexachlorobenzene in the rat and the rhesus monkey. J Agric Food Chem (1978) 1.00
Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation. Am Ind Hyg Assoc J (1996) 0.99
ICCVAM evaluation of the murine local lymph node assay. Conclusions and recommendations of an independent scientific peer review panel. Regul Toxicol Pharmacol (2001) 0.99
Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling. Arch Toxicol (2001) 0.98
The antimutagenic effect of vanillin and cinnamaldehyde on spontaneous mutation in Salmonella TA104 is due to a reduction in mutations at GC but not AT sites. Mutat Res (2001) 0.98
Methyl isocyanate: an evaluation of in vivo cytogenetic activity. Environ Mutagen (1987) 0.96
Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and Kepone. Arch Toxicol (1996) 0.95
Rhodostomin, a snake venom disintegrin, inhibits angiogenesis elicited by basic fibroblast growth factor and suppresses tumor growth by a selective alpha(v)beta(3) blockade of endothelial cells. Mol Pharmacol (2001) 0.95
Sister-chromatid exchange: second report of the Gene-Tox Program. Mutat Res (1993) 0.95
Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 rats. Toxicol Appl Pharmacol (1996) 0.94
Chemical mixtures from a public health perspective: the importance of research for informed decision making. Toxicology (1995) 0.94
Physiologically based pharmacokinetic/pharmacodynamic modeling of chemical mixtures and possible applications in risk assessment. Toxicology (1995) 0.93
A proposed approach to study the toxicology of complex mixtures of petroleum products: the integrated use of QSAR, lumping analysis and PBPK/PD modeling. Environ Health Perspect (1997) 0.93
Toxicology studies of a chemical mixture of 25 groundwater contaminants: hepatic and renal assessment, response to carbon tetrachloride challenge, and influence of treatment-induced water restriction. J Toxicol Environ Health (1994) 0.93
Pharmacokinetics, metabolism, and carcinogenicity of arsenic. Rev Environ Contam Toxicol (2001) 0.92
Toxicology studies of a chemical mixture of 25 groundwater contaminants. II. Immunosuppression in B6C3F1 mice. Fundam Appl Toxicol (1989) 0.92
Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent. Carcinogenesis (2001) 0.91
Regulation of quantal secretion by neurotrophic factors at developing motoneurons in Xenopus cell cultures. J Physiol (1997) 0.91
Risk assessment of chemical mixtures: biologic and toxicologic issues. Fundam Appl Toxicol (1993) 0.91
Bioassay-directed fractionation of 1-nitropyrene metabolites: generation of mutagrams by coupling reverse-phase HPLC with microsuspension mutagenicity assays. Mutagenesis (1990) 0.91
Enzymic sulphation of p-nitrophenol and steroids by larval gut tissues of the southern armyworm (Prodenia evidania Cramer). Biochem J (1972) 0.91
Vitamin D stores of urban women in Taipei: effect on bone density and bone turnover, and seasonal variation. Bone (1997) 0.91
ICCVAM evaluation of the murine local lymph node assay. Data analyses completed by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods. Regul Toxicol Pharmacol (2001) 0.90
Efficacy of a 24-week aerobic exercise program for osteopenic postmenopausal women. Calcif Tissue Int (2000) 0.90
Genetic toxicity of the benzene metabolite trans, trans-muconaldehyde in mammalian and bacterial cells. Mutat Res (1990) 0.89
Home-based trunk-strengthening exercise for osteoporotic and osteopenic postmenopausal women without fracture--a pilot study. Clin Rehabil (2005) 0.89
Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes. Recent Results Cancer Res (1998) 0.88
Enzymatic degradation of diazinon by rat liver microsomes. Life Sci (1969) 0.88
The effect of exposure regimen and duration on benzene-induced bone-marrow damage in mice. I. Sex comparison in DBA/2 mice. Mutat Res (1988) 0.88
Cytokinetic analysis of the impaired proliferative response of peripheral lymphocytes from aged humans to phytohemagglutinin. J Exp Med (1979) 0.88
A novel arylsulfatase A protein variant and genotype in two patients with major depression. J Affect Disord (1996) 0.87
Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): a computational method. Fundam Appl Toxicol (1996) 0.87
Biomarker assays in nipple aspirate fluid. Breast J (2002) 0.86
Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique. Mutat Res (1992) 0.86
Bone densitometry of proximal femur in Chinese subjects: gender differences in bone mass and bone areas. Bone (1997) 0.86
Antagonistic interactions of an arsenic-containing mixture in a multiple organ carcinogenicity bioassay. Cancer Lett (1998) 0.86
Periprosthetic bone mineral density of the distal femur after total knee arthroplasty. Int Orthop (1995) 0.86
Examination of the additivity assumption using the spiral and standard Salmonella assays to evaluate binary combinations of mutagens. Mutat Res (1995) 0.86
Development of source testing, analytical, and mutagenicity bioassay procedures for evaluating emissions from municipal and hospital waste combustors. Environ Health Perspect (1992) 0.85
Induction of micronuclei in mouse bone marrow cells: an evaluation of nucleoside analogues used in the treatment of AIDS. Environ Mol Mutagen (1991) 0.85
Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice. Mol Carcinog (1994) 0.85
Flexor tendon graft for late management of isolated rupture of the profundus tendon. J Trauma (1997) 0.85
Use of the microscreen phage-induction assay to assess the genotoxicity of 14 hazardous industrial wastes. Environ Mol Mutagen (1988) 0.85
The effect of aging on sister chromatid exchange. Mech Ageing Dev (1979) 0.85
In vivo rotational stability of the kinematic rotating hinge knee prosthesis. Clin Orthop Relat Res (1997) 0.84
Effects of caffeine and exercise on the development of bone: a densitometric and histomorphometric study in young Wistar rats. Bone (2002) 0.84
Test data--how much is not enough? Environ Mutagen (1984) 0.84
Responses of transgenic mouse lines p53(+/-) and Tg.AC to agents tested in conventional carcinogenicity bioassays. Toxicol Sci (2000) 0.84
In vivo genotoxicity of dichloroacetic acid: evaluation with the mouse peripheral blood micronucleus assay and the single cell gel assay. Environ Mol Mutagen (1996) 0.84
Use of Biobrane in pediatric scald burns--experience in 106 children. Burns (1998) 0.84
An analysis of gamma-ray-induced DNA damage in human blood leukocytes, lymphocytes and granulocytes. Mutat Res (1993) 0.84
Bromodeoxyuridine differential chromatid staining technique: a new approach to examining sister chromatid exchange and cell replication kinetics. Methods Cell Biol (1978) 0.84
In vivo BUdR labeling of mammalian chromosomes. Exp Cell Res (1976) 0.84
Influence of treatment to sacrifice time and the presence of BrdUrd on chemically-induced aberration rates in mouse marrow cells. Mutat Res (1990) 0.84
Primary vascular leiomyosarcoma of the femoral vein leading to metastases of scalp and lungs. Clin Oncol (R Coll Radiol) (2005) 0.84
Aneuploidy in mammalian somatic cells in vivo. Mutat Res (1986) 0.84
Comparison of cytogenetic effects of 3,4-epoxy-1-butene and 1,2:3, 4-diepoxybutane in mouse, rat and human lymphocytes following in vitro G0 exposures. Mutat Res (1999) 0.83
Sulphotransferases and phosphotransferases in insects. Comp Biochem Physiol B (1973) 0.83
Lethality and hepatotoxicity of complex waste mixtures. Environ Res (1988) 0.82
Evaluation of the nephrotoxicity of complex mixtures containing organics and metals: advantages and disadvantages of the use of real-world complex mixtures. Environ Health Perspect (1995) 0.82
The effectiveness of cyclic and continuous oral clodronate therapy on bone density and markers in osteopenic postmenopausal women. Calcif Tissue Int (1999) 0.82
Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals. Environ Mol Mutagen (1993) 0.82
Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella. Genetics (1994) 0.82
The use of bromodeoxyuridine labeling in the human lymphocyte HGPRT somatic mutation assay. Mutat Res (1987) 0.81
Thrombin enhances the adhesion and migration of human colon adenocarcinoma cells via increased beta 3-integrin expression on the tumour cell surface and their inhibition by the snake venom peptide, rhodostomin. Br J Cancer (1996) 0.81
Genotoxicity of inhibitors of DNA topoisomerases I (camptothecin) and II (m-AMSA) in vivo and in vitro. Mutagenesis (1990) 0.81
Use of four short-term tests to evaluate the mutagenicity of municipal water. J Toxicol Environ Health (1982) 0.81
Statistical design, analysis, and inference issues in studies using sister chromatid exchange. Basic Life Sci (1984) 0.81