Heterogeneity of vascular muscarinic receptors.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 2229100)

Published in J Auton Pharmacol on August 01, 1990

Authors

R M Eglen1, R L Whiting

Author Affiliations

1: Institute of Pharmacology, Syntex Research, Palo Alto, California 94303.

Articles citing this

Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current. Br J Pharmacol (1999) 0.99

Vasodilatation and smooth muscle membrane potential changes in arterioles from the guinea-pig small intestine. J Physiol (1995) 0.93

Release of endothelium-derived hyperpolarizing factor (EDHF) by M3 receptor stimulation in guinea-pig coronary artery. Br J Pharmacol (1995) 0.84

Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br J Pharmacol (1993) 0.83

Heterogeneity of muscarinic receptors in lamb isolated coronary resistance arteries. Br J Pharmacol (1993) 0.82

Actions of vasodilator nerves on arteriolar smooth muscle and neurotransmitter release from sympathetic nerves in the guinea-pig small intestine. J Physiol (1995) 0.81

The cholinomimetic agent bethanechol activates IK(ACh) in feline atrial myocytes. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.79

Contribution of the M3 muscarinic receptors to the vasodilator response to acetylcholine in the human forearm vascular bed. Br J Clin Pharmacol (2008) 0.78

Mechanisms underlying ACh induced modulation of neurogenic and applied ATP constrictions in the submucosal arterioles of the guinea-pig small intestine. Br J Pharmacol (1999) 0.75

Effect of the effluent released from the canine internal mammary artery after intraluminal and extraluminal perfusion of acetylcholine and adenosine diphosphate. J Biomed Sci (2009) 0.75

Articles by these authors

Muscarinic receptor subtypes: a critique of the current classification and a proposal for a working nomenclature. J Auton Pharmacol (1986) 1.79

The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro. Br J Pharmacol (1995) 1.57

Characterization of 5-HT3 and 'atypical' 5-HT receptors mediating guinea-pig ileal contractions in vitro. Br J Pharmacol (1990) 1.46

Methoctramine, a polymethylene tetraamine, differentiates three subtypes of muscarinic receptor in direct binding studies. Eur J Pharmacol (1988) 1.32

Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-beta-hydroxylase. Br J Pharmacol (1997) 1.29

Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat. Br J Pharmacol (1974) 1.27

Action of agonists and antagonists at muscarinic receptors present on ileum and atria in vitro. Br J Pharmacol (1985) 1.24

Identification of a single alpha 1-adrenoceptor corresponding to the alpha 1A-subtype in rat submaxillary gland. Br J Pharmacol (1989) 1.23

Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol. J Pharmacol Exp Ther (1990) 1.23

Differences between the alpha 2-adrenoceptor in rat submaxillary gland and the alpha 2A-and alpha 2B-adrenoceptor subtypes. Br J Pharmacol (1989) 1.20

5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch Pharmacol (1990) 1.20

The action of prostanoid receptor agonists and antagonists on smooth muscle and platelets. Br J Pharmacol (1988) 1.16

An improved valve device for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. J Pharm Pharmacol (1972) 1.14

Competitive and non-competitive antagonism exhibited by 'selective' antagonists at atrial and ileal muscarinic receptor subtypes. Br J Pharmacol (1987) 1.13

The pharmacological properties of the peptide, endothelin. Br J Pharmacol (1989) 1.12

Pharmacological characterization of RS 25259-197, a novel and selective 5-HT3 receptor antagonist, in vivo. Br J Pharmacol (1995) 1.04

Direct binding studies on ileal and cardiac muscarinic receptors. Br J Pharmacol (1987) 1.02

Characterization of the muscarinic receptor subtype mediating contractions of the guinea-pig uterus. Br J Pharmacol (1989) 1.01

Methoctramine reveals heterogeneity of M2 muscarinic receptors in longitudinal ileal smooth muscle membranes. Eur J Pharmacol (1988) 1.00

An improved technique for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. Br J Pharmacol (1972) 1.00

The interaction of parafluorohexahydrosiladiphenidol at muscarinic receptors in vitro. Br J Pharmacol (1990) 0.98

Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br J Pharmacol (1991) 0.97

The interaction of methoctramine and himbacine at atrial, smooth muscle and endothelial muscarinic receptors in vitro. Br J Pharmacol (1988) 0.96

Negative and positive inotropic responses to muscarinic agonists in guinea pig and rat atria in vitro. J Pharmacol Exp Ther (1988) 0.95

Comparison of the muscarinic receptors of the guinea-pig oesophageal muscularis mucosae and trachea in vitro. J Auton Pharmacol (1988) 0.92

Muscarinic activity of McN-A-343 and its value in muscarinic receptor classification. Br J Pharmacol (1987) 0.92

On the interaction of gallamine with muscarinic receptor subtypes. Eur J Pharmacol (1990) 0.91

The mechanism of the antihypertensive action of -methyldopa in hypertensive rats. Eur J Pharmacol (1973) 0.91

Direct labeling of rat M3-muscarinic receptors by [3H]4DAMP. Eur J Pharmacol (1989) 0.90

Analysis of muscarinic cholinoceptors mediating phosphoinositide hydrolysis in guinea pig cardiac muscle. Eur J Pharmacol (1992) 0.90

Affinity of muscarinic receptor antagonists for three putative muscarinic receptor binding sites. Br J Pharmacol (1989) 0.90

Interaction of p-F-HHSiD (p-Fluoro-hexahydrosila-difenidol) at muscarinic receptors in guinea-pig trachea. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.89

Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line. Naunyn Schmiedebergs Arch Pharmacol (1989) 0.89

Effects of anxiolytic and anxiogenic drugs on exploratory activity in a simple model of anxiety in mice. Neuropharmacology (1989) 0.88

Characterization of the prostanoid receptor profile of enprostil and isomers in smooth muscle and platelets in vitro. Br J Pharmacol (1989) 0.88

The binding of [3H]4-diphenylacetoxy-N-methylpiperidine methiodide to longitudinal ileal smooth muscle muscarinic receptors. Eur J Pharmacol (1990) 0.87

Investigation of the prostacyclin (IP) receptor antagonist RO1138452 on isolated blood vessel and platelet preparations. Br J Pharmacol (2006) 0.87

Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. Neurochem Res (1991) 0.87

Estimation of apparent agonist affinity constants using desensitization of the ileal muscarinic receptor. J Pharmacol Exp Ther (1987) 0.86

Determination of the muscarinic receptor subtype mediating vasodilatation. Br J Pharmacol (1985) 0.86

Functional and direct binding studies using subtype selective muscarinic receptor antagonists. Br J Pharmacol (1988) 0.85

Agonist action of indole derivatives at 5-HT1-like, 5-HT3, and 5HT4 receptors in vitro. J Auton Pharmacol (1992) 0.85

Problems associated with the application of the Cheng-Prusoff relationship to estimate atropine affinity constants using functional tissue responses. Life Sci (1989) 0.84

Pharmacology and structure-activity relationships of alpha 2-adrenoceptor antagonists. Prog Med Chem (1986) 0.83

Assessment of imiloxan as a selective alpha 2B-adrenoceptor antagonist. Br J Pharmacol (1990) 0.83

Comparison of the positive chronotropic response to 5-hydroxytryptamine with beta-adrenoceptor agonists on the guinea pig atria in vitro. J Cardiovasc Pharmacol (1989) 0.82

The human astrocytoma cell line 1321 N1 contains M2-glandular type muscarinic receptors linked to phosphoinositide turnover. Br J Pharmacol (1989) 0.82

Structure-activity relationships for 2-substituted imidazoles as alpha 2-adrenoceptor antagonists. J Med Chem (1982) 0.80

(R) and (S) RS 56532: mixed 5-HT3 and 5-HT4 receptor ligands with opposing enantiomeric selectivity. Neuropharmacology (1994) 0.80

The mode of action of -methyldopa. Br J Pharmacol (1972) 0.80

The interaction of hexamethonium with muscarinic receptor subtypes in vitro. Br J Pharmacol (1989) 0.80

PC12 phaeochromocytoma cells contain an atypical muscarinic receptor binding site. Br J Pharmacol (1989) 0.80

RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther (1993) 0.80

Characterization of muscarinic receptors mediating release of epithelial derived relaxant factor (EpDRF) in guinea-pig isolated trachea. Naunyn Schmiedebergs Arch Pharmacol (1991) 0.80

Differential effects of pertussis toxin and lithium on muscarinic responses in the atria and ileum: evidence for receptor heterogeneity. Br J Pharmacol (1987) 0.79

Differential effects of pertussis toxin on muscarinic responses in isolated atria and smooth muscle. J Auton Pharmacol (1988) 0.78

First pharmacological characterization of TRH receptors linked to phosphoinositide hydrolysis in GH3 pituitary cells using agonist specificity of eight TRH analogs. Biochem Biophys Res Commun (1989) 0.78

Acute desensitization of muscarinic receptors in the isolated guinea-pig ileal longitudinal muscle. J Auton Pharmacol (1992) 0.78

RS-61756-007: a potent and selective thromboxane receptor (TP) agonist. J Pharm Pharmacol (1989) 0.78

Comparative properties of the dopamine transport complex in dog and rodent brain: striatal [(3)H]GBR12935 binding and [(3)H]dopamine uptake. Neurochem Int (1989) 0.77

Pharmacological characterization of the N-methyl-D-aspartate (NMDA) receptor-channel in rodent and dog brain and rat spinal cord using [3H]MK-801 binding. Neurochem Res (1991) 0.77

The action of (+/-)L-660,863 [(+/-)3-(3-amino-1,2,4-oxadiazole-5-yl)-quinuclidine] at muscarinic receptor subtypes in vitro. Naunyn Schmiedebergs Arch Pharmacol (1992) 0.77

M3 muscarinic receptors on murine HSDM1C1 cells: further functional, regulatory, and receptor binding studies. Neurochem Res (1995) 0.77

Analogs of thyrotropin-releasing hormone (TRH): receptor affinities in brains, spinal cords, and pituitaries of different species. Neurochem Res (1991) 0.77

Radioligand binding characteristics of the chicken cardiac muscarinic receptor. Naunyn Schmiedebergs Arch Pharmacol (1989) 0.77

Stimulation of prostaglandin D2 receptors on human platelets by analogs of prostacyclin. Prostaglandins (1991) 0.77

Desensitization and functional antagonism by beta-adrenoceptor and muscarinic receptor agonists, respectively: a comparison with receptor alkylation for calculation of apparent agonist affinity. Br J Pharmacol (1991) 0.77

Proceedings: BRL 13776: a novel antihypertensive agent with interesting noradrenaline-depleting properties. Br J Pharmacol (1976) 0.77

Chronic manipulation of dietary salt modulates renal physiology and kidney dopamine receptor subtypes: functional and autoradiographic studies. Gen Pharmacol (1995) 0.76

The neuropeptide bradykinin stimulates phosphoinositide turnover in HSDM1C1 cells: B2-antagonist-sensitive responses and receptor binding studies. Neurochem Res (1993) 0.76

The effect of the 5-HT3 receptor antagonist, RS-42358-197, in animal models of anxiety. Eur J Pharmacol (1993) 0.76

Characterization of the interaction of the cervane alkaloid, imperialine, at muscarinic receptors in vitro. Naunyn Schmiedebergs Arch Pharmacol (1992) 0.76

Proceedings: Changes in serum and tissue lipid levels induced by metacorticoid hypertension in rats. Br J Pharmacol (1973) 0.75

BRL 13776: a novel antihypertensive agent with interesting monoamine depleting properties. Br J Pharmacol (1977) 0.75

The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys. Neuroreport (1996) 0.75

On-line computation of peripheral resistance and stroke volume in the conscious cat obtained by the use of chronically-implanted electromagnetic flow transducer [proceedings]. Br J Pharmacol (1977) 0.75

Heterogeneity of muscarinic receptors in bovine adrenal medulla. Proc West Pharmacol Soc (1989) 0.75

Pharmacological profile of the dopamine agonist, RS-45946. Proc West Pharmacol Soc (1990) 0.75

Cellular action of nicardipine. Am J Cardiol (1989) 0.75

Quantitative autoradiography demonstrates selective modulation of rat brain regional dopamine (D1 and D2) receptor subtypes after chronic manipulation of dietary salt. Neurochem Res (1995) 0.75

Prognosis for expanded u.s. Production of crude oil. Science (1974) 0.75

A pharmacological comparison of [3H]GBR12935 binding to rodent striatal and kidney homogenates: binding to dopamine transporters? Neurochem Int (1992) 0.75

Synthesis and antihypertensive activity of a series of 8-substituted 1-oxa-3,8-diazaspiro[4.5]decan-2-ones. J Med Chem (1981) 0.75

Antihypertensive 1-acyl-4-[2-(1,4-benzodioxan-2-yl)-2-hydroxyethylamino]pip eridines. J Pharm Sci (1987) 0.75

Antihypertensive 9-substituted 1-oxa-4,9-diazaspiro[5.5]undecan-3-ones. J Med Chem (1983) 0.75

Antihypertensive aminotetralins related to labetalol and medroxalol. J Pharm Sci (1986) 0.75

Pharmacological properties of endothelin in vitro. Proc West Pharmacol Soc (1989) 0.75

BRL 8242 (2-[2-benzimidazolyl]-amino-2-imidazoline dihydrochloride), a new inhibitor of dopamine-beta-hydroxylase with antihypertensive activity. Eur J Pharmacol (1976) 0.75

Pharmacological profile of the dopamine (DA) agonists, RS-12254. Proc West Pharmacol Soc (1991) 0.75

Syntheses and hypotensive properties of substituted 2-aminotetralins. J Pharm Sci (1985) 0.75

Animal pharmacology of nicardipine and its clinical relevance. Am J Cardiol (1987) 0.75

Stimulation of inositol phosphate production in clonal HSDM1C1 cells by endothelins and sarafotoxin. Biochem Pharmacol (1990) 0.75

Dog cerebral cortex contains mu-, delta- and kappa-opioid receptors at different densities: apparent lack of evidence for subtypes of the kappa-receptor using selective radioligands. Brain Res (1990) 0.75

Differential affinities of TRH analogs at the mammalian spinal cord TRH receptor: implications for therapy in spinal injuries. Neurosci Lett (1989) 0.75

Identification of B(2)-bradykinin receptors in guinea pig brain regions, spinal cord and peripheral tissues. Neurochem Int (1991) 0.75

Cardiovascular effects of nepicastat (RS-25560-197), a novel dopamine beta-hydroxylase inhibitor. J Cardiovasc Pharmacol (1998) 0.75